Ganglioside GM3 (BioDeep_00000844583)

   


代谢物信息卡片


Ganglioside GM3

化学式: C59H108N2O21 (1180.7444198)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)CO)O)OC3(CC(C(C(O3)C(C(CO)O)O)NC(=O)C)O)C(=O)O)O)O)O)C(C=CCCCCCCCCCCCCC)O
InChI: InChI=1S/C59H108N2O21/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(69)61-40(41(66)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-77-56-51(73)50(72)53(45(37-64)79-56)80-57-52(74)55(49(71)44(36-63)78-57)82-59(58(75)76)34-42(67)47(60-39(3)65)54(81-59)48(70)43(68)35-62/h30,32,40-45,47-57,62-64,66-68,70-74H,4-29,31,33-38H2,1-3H3,(H,60,65)(H,61,69)(H,75,76)/b32-30+/t40-,41+,42-,43+,44+,45+,47+,48+,49-,50+,51+,52+,53+,54+,55-,56+,57-,59-/m0/s1

描述信息

同义名列表

1 个代谢物同义名

Ganglioside GM3



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yuanqing Gu, Björn M Reinhard. Membrane fluidity properties of lipid-coated polylactic acid nanoparticles. Nanoscale. 2024 May; 16(17):8533-8545. doi: 10.1039/d3nr06464f. [PMID: 38595322]
  • Fangni Zhang, Kan Li, Wenhui Zhang, Ziyan Zhao, Fangyuan Chang, Jie Du, Xu Zhang, Kaiwen Bao, Chunyong Zhang, Lei Shi, Zongwei Liu, Xiangchen Dai, Chen Chen, Dao Wen Wang, Zhong Xian, Hongfeng Jiang, Ding Ai. Ganglioside GM3 Protects Against Abdominal Aortic Aneurysm by Suppressing Ferroptosis in Vascular Smooth Muscle Cells. Circulation. 2023 Nov; ?(?):. doi: 10.1161/circulationaha.123.066110. [PMID: 38018467]
  • Mariko Komuro, Hinano Mizugaki, Masaki Nagane, Misako Morimoto, Tomoki Fukuyama, Kikumi Ogihara, Yuko Naya, Emi Yokomori, Kimika Kaneshima, Yasushi Kawakami, Junichi Kamiie, Yuki Shibata, Mira Suzuki, Takuto Shimizu, Nagako Kawashima, Mariko Okamoto, Teruo Ikeda, Tadashi Yamashita. Ganglioside GM3 deficiency enhances mast cell sensitivity. The FEBS journal. 2023 09; 290(17):4268-4280. doi: 10.1111/febs.16806. [PMID: 37098812]
  • Tanushree Das, Chaitali Mukhopadhyay. Comparison and Possible Binding Orientations of SARS-CoV-2 Spike N-Terminal Domain for Gangliosides GM3 and GM1. The journal of physical chemistry. B. 2023 08; 127(31):6940-6948. doi: 10.1021/acs.jpcb.3c02286. [PMID: 37523476]
  • Motohide Murate, Noriko Yokoyama, Nario Tomishige, Ludovic Richert, Nicolas Humbert, Brigitte Pollet, Asami Makino, Nozomu Kono, Laura Mauri, Junken Aoki, Yasushi Sako, Sandro Sonnino, Naoko Komura, Hiromune Ando, Mika K Kaneko, Yukinari Kato, Kei-Ichiro Inamori, Jin-Ichi Inokuchi, Yves Mély, Kazuhisa Iwabuchi, Toshihide Kobayashi. Cell density-dependent membrane distribution of ganglioside GM3 in melanoma cells. Cellular and molecular life sciences : CMLS. 2023 May; 80(6):167. doi: 10.1007/s00018-023-04813-9. [PMID: 37249637]
  • Simon Fridolf, Quoc Dat Pham, Jon Pallbo, Katja Bernfur, Sara Linse, Daniel Topgaard, Emma Sparr. Ganglioside GM3 stimulates lipid-protein co-assembly in α-synuclein amyloid formation. Biophysical chemistry. 2023 02; 293(?):106934. doi: 10.1016/j.bpc.2022.106934. [PMID: 36493587]
  • Giulia Lunghi, Maria Fazzari, Maria Grazia Ciampa, Laura Mauri, Erika Di Biase, Elena Chiricozzi, Sandro Sonnino. Regulation of signal transduction by gangliosides in lipid rafts: focus on GM3-IR and GM1-TrkA interactions. FEBS letters. 2022 12; 596(24):3124-3132. doi: 10.1002/1873-3468.14532. [PMID: 36331354]
  • Han Zang, Menna Siddiqui, Suryaram Gummuluru, Wilson W Wong, Björn M Reinhard. Ganglioside-Functionalized Nanoparticles for Chimeric Antigen Receptor T-Cell Activation at the Immunological Synapse. ACS nano. 2022 11; 16(11):18408-18420. doi: 10.1021/acsnano.2c06516. [PMID: 36282488]
  • Tong Rong, Bo Wei, Meiying Ao, Haonan Zhao, Yuanfang Li, Yang Zhang, Ying Qin, Jinhua Zhou, Fenfen Zhou, Yong Chen. Enhanced Anti-Atherosclerotic Efficacy of pH-Responsively Releasable Ganglioside GM3 Delivered by Reconstituted High-Density Lipoprotein. International journal of molecular sciences. 2021 Dec; 22(24):. doi: 10.3390/ijms222413624. [PMID: 34948420]
  • Mira Suzuki, Masaki Nagane, Kazuhiro Kato, Akinori Yamauchi, Takuto Shimizu, Hiroko Yamashita, Naoyuki Aihara, Junichi Kamiie, Nagako Kawashima, Shokichi Naito, Tadashi Yamashita. Endothelial ganglioside GM3 regulates angiogenesis in solid tumors. Biochemical and biophysical research communications. 2021 09; 569(?):10-16. doi: 10.1016/j.bbrc.2021.06.063. [PMID: 34216992]
  • Mikito Nakano, Shinya Hanashima, Toshiaki Hara, Kazuya Kabayama, Yuya Asahina, Hironobu Hojo, Naoko Komura, Hiromune Ando, Thomas K M Nyholm, J Peter Slotte, Michio Murata. FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers. Biochimica et biophysica acta. Biomembranes. 2021 08; 1863(8):183623. doi: 10.1016/j.bbamem.2021.183623. [PMID: 33933428]
  • Shiomi Koudatsu, Tatsunori Masatani, Rikako Konishi, Masahito Asada, Hassan Hakimi, Yuna Kurokawa, Kanna Tomioku, Osamu Kaneko, Akikazu Fujita. Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane. Scientific reports. 2021 07; 11(1):14890. doi: 10.1038/s41598-021-94037-3. [PMID: 34290278]
  • Shuqiang Chen, Ming Wang, Li Li, Jun Wang, Xuhui Ma, Hengde Zhang, Yang Cai, Bin Kang, Jianlei Huang, Bo Li. High-coverage targeted lipidomics revealed dramatic lipid compositional changes in asthenozoospermic spermatozoa and inverse correlation of ganglioside GM3 with sperm motility. Reproductive biology and endocrinology : RB&E. 2021 Jul; 19(1):105. doi: 10.1186/s12958-021-00792-3. [PMID: 34233713]
  • Hai Yu, Madhusudhan Reddy Gadi, Yuanyuan Bai, Libo Zhang, Lei Li, Jun Yin, Peng G Wang, Xi Chen. Chemoenzymatic Total Synthesis of GM3 Gangliosides Containing Different Sialic Acid Forms and Various Fatty Acyl Chains. The Journal of organic chemistry. 2021 07; 86(13):8672-8682. doi: 10.1021/acs.joc.1c00450. [PMID: 34152144]
  • Rhona McGonigal, Jennifer A Barrie, Denggao Yao, Lauren E Black, Mark McLaughlin, Hugh J Willison. Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice. Journal of neurochemistry. 2021 07; 158(2):217-232. doi: 10.1111/jnc.15365. [PMID: 33864399]
  • Marjorie Damian, Maxime Louet, Antoniel Augusto Severo Gomes, Céline M'Kadmi, Séverine Denoyelle, Sonia Cantel, Sophie Mary, Paulo M Bisch, Jean-Alain Fehrentz, Laurent J Catoire, Nicolas Floquet, Jean-Louis Banères. Allosteric modulation of ghrelin receptor signaling by lipids. Nature communications. 2021 06; 12(1):3938. doi: 10.1038/s41467-021-23756-y. [PMID: 34168117]
  • Xu-Guang Yin, Jie Lu, Jian Wang, Ru-Yan Zhang, Xi-Feng Wang, Chun-Miao Liao, Xiao-Peng Liu, Zheng Liu, Jun Guo. Synthesis and Evaluation of Liposomal Anti-GM3 Cancer Vaccine Candidates Covalently and Noncovalently Adjuvanted by αGalCer. Journal of medicinal chemistry. 2021 02; 64(4):1951-1965. doi: 10.1021/acs.jmedchem.0c01186. [PMID: 33539088]
  • Takuto Shimizu, Masaki Nagane, Mira Suzuki, Akinori Yamauchi, Kazuhiro Kato, Nagako Kawashima, Yuki Nemoto, Takuya Maruo, Yasushi Kawakami, Tadashi Yamashita. Tumor hypoxia regulates ganglioside GM3 synthase, which contributes to oxidative stress resistance in malignant melanoma. Biochimica et biophysica acta. General subjects. 2020 12; 1864(12):129723. doi: 10.1016/j.bbagen.2020.129723. [PMID: 32861756]
  • Hirotaka Kanoh, Takahiro Nitta, Shinji Go, Kei-Ichiro Inamori, Lucas Veillon, Wataru Nihei, Mayu Fujii, Kazuya Kabayama, Atsushi Shimoyama, Koichi Fukase, Umeharu Ohto, Toshiyuki Shimizu, Taku Watanabe, Hiroki Shindo, Sorama Aoki, Kenichi Sato, Mika Nagasaki, Yutaka Yatomi, Naoko Komura, Hiromune Ando, Hideharu Ishida, Makoto Kiso, Yoshihiro Natori, Yuichi Yoshimura, Asia Zonca, Anna Cattaneo, Marilena Letizia, Maria Ciampa, Laura Mauri, Alessandro Prinetti, Sandro Sonnino, Akemi Suzuki, Jin-Ichi Inokuchi. Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity. The EMBO journal. 2020 06; 39(12):e101732. doi: 10.15252/embj.2019101732. [PMID: 32378734]
  • Zhixiong Deng, Xuemei Lu, Cheng Xu, Bing Yuan, Kai Yang. Lipid-specific interactions determine the organization and dynamics of membrane-active peptide melittin. Soft matter. 2020 Apr; 16(14):3498-3504. doi: 10.1039/d0sm00046a. [PMID: 32215386]
  • Bo Hyun Kim, Won Seok Ju, Ji-Su Kim, Sun-Uk Kim, Soon Ju Park, Sean M Ward, Ju Hyeong Lyu, Young-Kug Choo. Effects of Gangliosides on Spermatozoa, Oocytes, and Preimplantation Embryos. International journal of molecular sciences. 2019 Dec; 21(1):. doi: 10.3390/ijms21010106. [PMID: 31877897]
  • Carmen Bedia, Miriam Badia, Laia Muixí, Thierry Levade, Romà Tauler, Angels Sierra. GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells. Scientific reports. 2019 10; 9(1):14241. doi: 10.1038/s41598-019-50761-5. [PMID: 31578452]
  • Meiying Ao, Kun Wang, Xing Zhou, Guo Chen, Yun Zhou, Bo Wei, Wenxiang Shao, Jie Huang, Huanhuan Liao, Zhexuan Wang, Yanan Sun, Sufen Zeng, Yong Chen. Exogenous GM3 ganglioside inhibits atherosclerosis via multiple steps: A potential atheroprotective drug. Pharmacological research. 2019 10; 148(?):104445. doi: 10.1016/j.phrs.2019.104445. [PMID: 31526872]
  • Pieter Vrijens, Sam Noppen, Talitha Boogaerts, Els Vanstreels, Roberto Ronca, Paola Chiodelli, Manon Laporte, Evelien Vanderlinden, Sandra Liekens, Annelies Stevaert, Lieve Naesens. Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway. The Journal of general virology. 2019 04; 100(4):583-601. doi: 10.1099/jgv.0.001235. [PMID: 30762518]
  • Christophe Paget, Shenglou Deng, Daphnée Soulard, David A Priestman, Silvia Speca, Johanna von Gerichten, Anneliese O Speak, Ashish Saroha, Yael Pewzner-Jung, Anthony H Futerman, Thierry Mallevaey, Christelle Faveeuw, Xiaobo Gu, Frances M Platt, Roger Sandhoff, François Trottein. TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells. PLoS biology. 2019 03; 17(3):e3000169. doi: 10.1371/journal.pbio.3000169. [PMID: 30822302]
  • Wataru Nihei, Masakazu Nagafuku, Hirotaka Hayamizu, Yuta Odagiri, Yumi Tamura, Yui Kikuchi, Lucas Veillon, Hirotaka Kanoh, Kei-Ichiro Inamori, Kenta Arai, Kazuya Kabayama, Koichi Fukase, Jin-Ichi Inokuchi. NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains. Journal of lipid research. 2018 11; 59(11):2181-2187. doi: 10.1194/jlr.m089201. [PMID: 30242108]
  • Fangda Xu, Asanga Bandara, Hisashi Akiyama, Behnaz Eshaghi, David Stelter, Tom Keyes, John E Straub, Suryaram Gummuluru, Björn M Reinhard. Membrane-wrapped nanoparticles probe divergent roles of GM3 and phosphatidylserine in lipid-mediated viral entry pathways. Proceedings of the National Academy of Sciences of the United States of America. 2018 09; 115(39):E9041-E9050. doi: 10.1073/pnas.1804292115. [PMID: 30190430]
  • Kei-Ichiro Inamori, Hideki Ito, Yumi Tamura, Takahiro Nitta, Xiaohua Yang, Wataru Nihei, Fumi Shishido, Susumu Imazu, Sohei Tsukita, Tetsuya Yamada, Hideki Katagiri, Jin-Ichi Inokuchi. Deficient ganglioside synthesis restores responsiveness to leptin and melanocortin signaling in obese KKAy mice. Journal of lipid research. 2018 08; 59(8):1472-1481. doi: 10.1194/jlr.m085753. [PMID: 29880531]
  • Xueheng Zhao, Marion G Brusadelli, Sharon Sauter, Melinda Butsch Kovacic, Wujuan Zhang, Lindsey E Romick-Rosendale, Paul F Lambert, Kenneth D R Setchell, Susanne I Wells. Lipidomic Profiling Links the Fanconi Anemia Pathway to Glycosphingolipid Metabolism in Head and Neck Cancer Cells. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 06; 24(11):2700-2709. doi: 10.1158/1078-0432.ccr-17-3686. [PMID: 29530934]
  • Kenichi G N Suzuki, Hiromune Ando, Naoko Komura, Miku Konishi, Akihiro Imamura, Hideharu Ishida, Makoto Kiso, Takahiro K Fujiwara, Akihiro Kusumi. Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs. Methods in enzymology. 2018; 598(?):267-282. doi: 10.1016/bs.mie.2017.06.038. [PMID: 29306438]
  • Kenichi G N Suzuki, Hiromune Ando, Naoko Komura, Takahiro K Fujiwara, Makoto Kiso, Akihiro Kusumi. Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging. Biochimica et biophysica acta. General subjects. 2017 Oct; 1861(10):2494-2506. doi: 10.1016/j.bbagen.2017.07.012. [PMID: 28734966]
  • Fumi Shishido, Satoshi Uemura, Takahiro Nitta, Jin-Ichi Inokuchi. Identification of a new liver-specific c-type mRNA transcriptional variant for mouse ST3GAL5 (GM3/GM4 synthase). Glycoconjugate journal. 2017 10; 34(5):651-659. doi: 10.1007/s10719-017-9788-1. [PMID: 28808804]
  • Martin Dufresne, Daniel Guneysu, Nathan Heath Patterson, Mieczyslaw Martin Marcinkiewicz, Anthony Regina, Michel Demeule, Pierre Chaurand. Multimodal detection of GM2 and GM3 lipid species in the brain of mucopolysaccharidosis type II mouse by serial imaging mass spectrometry and immunohistochemistry. Analytical and bioanalytical chemistry. 2017 Feb; 409(5):1425-1433. doi: 10.1007/s00216-016-0076-x. [PMID: 27873002]
  • Duncan Hieu M Dam, Xiao-Qi Wang, Sarah Sheu, Mahima Vijay, Desmond Shipp, Luke Miller, Amy S Paller. Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility. The Journal of investigative dermatology. 2017 02; 137(2):440-448. doi: 10.1016/j.jid.2016.09.028. [PMID: 27729281]
  • Robin B Chan, Adler J Perotte, Bowen Zhou, Christopher Liong, Evan J Shorr, Karen S Marder, Un J Kang, Cheryl H Waters, Oren A Levy, Yimeng Xu, Hong Bin Shim, Itsik Pe'er, Gilbert Di Paolo, Roy N Alcalay. Elevated GM3 plasma concentration in idiopathic Parkinson's disease: A lipidomic analysis. PloS one. 2017; 12(2):e0172348. doi: 10.1371/journal.pone.0172348. [PMID: 28212433]
  • George Hedger, David Shorthouse, Heidi Koldsø, Mark S P Sansom. Free Energy Landscape of Lipid Interactions with Regulatory Binding Sites on the Transmembrane Domain of the EGF Receptor. The journal of physical chemistry. B. 2016 08; 120(33):8154-63. doi: 10.1021/acs.jpcb.6b01387. [PMID: 27109430]
  • J M Wentworth, G Naselli, K Ngui, G K Smyth, R Liu, P E O'Brien, C Bruce, J Weir, M Cinel, P J Meikle, L C Harrison. GM3 ganglioside and phosphatidylethanolamine-containing lipids are adipose tissue markers of insulin resistance in obese women. International journal of obesity (2005). 2016 Apr; 40(4):706-13. doi: 10.1038/ijo.2015.223. [PMID: 26499445]
  • Fangda Xu, Michael Reiser, Xinwei Yu, Suryaram Gummuluru, Lee Wetzler, Björn M Reinhard. Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona Formation. ACS nano. 2016 Jan; 10(1):1189-200. doi: 10.1021/acsnano.5b06501. [PMID: 26720275]
  • David Shorthouse, George Hedger, Heidi Koldsø, Mark S P Sansom. Molecular simulations of glycolipids: Towards mammalian cell membrane models. Biochimie. 2016 Jan; 120(?):105-9. doi: 10.1016/j.biochi.2015.09.033. [PMID: 26427555]
  • Dayong Xu, Libin Yang, Yunpeng Li, Yongqiang Sun. Clinical study of ganglioside (GM) combined with methylprednisolone (MP) for early acute spinal injury. Pakistan journal of pharmaceutical sciences. 2015 Mar; 28(2 Suppl):701-4. doi: ". [PMID: 25796161]
  • Masakazu Nagafuku, Takashige Sato, Saya Sato, Kyoko Shimizu, Toshio Taira, Jin-Ichi Inokuchi. Control of homeostatic and pathogenic balance in adipose tissue by ganglioside GM3. Glycobiology. 2015 Mar; 25(3):303-18. doi: 10.1093/glycob/cwu112. [PMID: 25303960]
  • Nadia Martinez-Martin, Abel Viejo-Borbolla, Rocío Martín, Soledad Blanco, Jeffrey L Benovic, Marcus Thelen, Antonio Alcamí. Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization. Nature communications. 2015 Jan; 6(?):6163. doi: 10.1038/ncomms7163. [PMID: 25625471]
  • Igor Vukovic, Josko Bozic, Anita Markotic, Srecko Ljubicic, Tina Ticinovic Kurir. The missing link - likely pathogenetic role of GM3 and other gangliosides in the development of diabetic nephropathy. Kidney & blood pressure research. 2015; 40(3):306-14. doi: 10.1159/000368506. [PMID: 26043887]
  • Francesca Margheri, Laura Papucci, Nicola Schiavone, Riccardo D'Agostino, Silvana Trigari, Simona Serratì, Anna Laurenzana, Alessio Biagioni, Cristina Luciani, Anastasia Chillà, Elena Andreucci, Tommaso Del Rosso, Giancarlo Margheri, Mario Del Rosso, Gabriella Fibbi. Differential uPAR recruitment in caveolar-lipid rafts by GM1 and GM3 gangliosides regulates endothelial progenitor cells angiogenesis. Journal of cellular and molecular medicine. 2015 Jan; 19(1):113-23. doi: 10.1111/jcmm.12410. [PMID: 25313007]
  • Mari L DeMarco. Molecular dynamics simulations of membrane- and protein-bound glycolipids using GLYCAM. Methods in molecular biology (Clifton, N.J.). 2015; 1273(?):379-90. doi: 10.1007/978-1-4939-2343-4_23. [PMID: 25753721]
  • Kazuya I P J Hidari, Maho Yamaguchi, Fumihiko Ueno, Tomoko Abe, Kazuhiro Yoshida, Takashi Suzuki. Influenza virus utilizes N-linked sialoglycans as receptors in A549 cells. Biochemical and biophysical research communications. 2013 Jul; 436(3):394-9. doi: 10.1016/j.bbrc.2013.05.112. [PMID: 23747419]
  • G Margheri, R D'Agostino, M Del Rosso, S Trigari. Fabrication of GM3-enriched sphingomyelin/cholesterol solid-supported lipid membranes on Au/SiO2 plasmonic substrates. Lipids. 2013 Jul; 48(7):739-47. doi: 10.1007/s11745-013-3789-z. [PMID: 23591593]
  • Qiu Yan, Daniel Q Bach, Nandita Gatla, Ping Sun, Ji-Wei Liu, Jian-Yun Lu, Amy S Paller, Xiao-Qi Wang. Deacetylated GM3 promotes uPAR-associated membrane molecular complex to activate p38 MAPK in metastatic melanoma. Molecular cancer research : MCR. 2013 Jun; 11(6):665-75. doi: 10.1158/1541-7786.mcr-12-0270-t. [PMID: 23525268]
  • Jacques Fantini, Nouara Yahi. The driving force of alpha-synuclein insertion and amyloid channel formation in the plasma membrane of neural cells: key role of ganglioside- and cholesterol-binding domains. Advances in experimental medicine and biology. 2013; 991(?):15-26. doi: 10.1007/978-94-007-6331-9_2. [PMID: 23775688]
  • G Dawson, M Fuller, K M Helmsley, J J Hopwood. Abnormal gangliosides are localized in lipid rafts in Sanfilippo (MPS3a) mouse brain. Neurochemical research. 2012 Jun; 37(6):1372-80. doi: 10.1007/s11064-012-0761-x. [PMID: 22484966]
  • Qianli Wang, Zhifang Zhou, Shouchu Tang, Zhongwu Guo. Carbohydrate-monophosphoryl lipid a conjugates are fully synthetic self-adjuvanting cancer vaccines eliciting robust immune responses in the mouse. ACS chemical biology. 2012 Jan; 7(1):235-40. doi: 10.1021/cb200358r. [PMID: 22013921]
  • Kazuya Kabayama. [Modulation of growth factor receptors in membrane microdomains]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2012; 132(4):417-23. doi: 10.1248/yakushi.132.417. [PMID: 22465916]
  • Satoshi Uemura. [The regulation of ganglioside GM3 synthesis]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2012; 132(8):895-901. doi: 10.1248/yakushi.132.895. [PMID: 22864347]
  • Bernard Desbat, Eloïse Lancelot, Tino Krell, Marie-Claire Nicolaï, Fred Vogel, Michel Chevalier, Frédéric Ronzon. Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface. Langmuir : the ACS journal of surfaces and colloids. 2011 Nov; 27(22):13675-83. doi: 10.1021/la2027175. [PMID: 21981550]
  • Vireak Thon, Kam Lau, Hai Yu, Bao K Tran, Xi Chen. PmST2: a novel Pasteurella multocida glycolipid α2-3-sialyltransferase. Glycobiology. 2011 Sep; 21(9):1206-16. doi: 10.1093/glycob/cwr054. [PMID: 21515586]
  • Marine Hovakimyan, Oliver Stachs, Maria Reichard, Hermann Mascher, Jan Lukas, Moritz Johannes Frech, Rudolf Guthoff, Martin Witt, Arndt Rolfs, Andreas Wree. Morphological alterations of the cornea in the mouse model of niemann-pick disease type c1. Cornea. 2011 Jul; 30(7):796-803. doi: 10.1097/ico.0b013e3182012a33. [PMID: 21317782]
  • A Miranda, J de León, L Roque-Navarro, L E Fernández. Cytofluorimetric evaluation of N-glycolylated GM3 ganglioside expression on murine leukocytes. Immunology letters. 2011 Jun; 137(1-2):38-45. doi: 10.1016/j.imlet.2011.02.001. [PMID: 21324343]
  • Ünal Coskun, Michał Grzybek, David Drechsel, Kai Simons. Regulation of human EGF receptor by lipids. Proceedings of the National Academy of Sciences of the United States of America. 2011 May; 108(22):9044-8. doi: 10.1073/pnas.1105666108. [PMID: 21571640]
  • Daniel W Bergner, Theresa B Kuhlenschmidt, William P Hanafin, Lawrence D Firkins, Mark S Kuhlenschmidt. Inhibition of rotavirus infectivity by a neoglycolipid receptor mimetic. Nutrients. 2011 02; 3(2):228-44. doi: 10.3390/nu3020228. [PMID: 22254094]
  • Anthony Rusciani, Laurent Duca, Hervé Sartelet, Aurore Chatron-Colliet, Hélène Bobichon, Dominique Ploton, Richard Le Naour, Sébastien Blaise, Laurent Martiny, Laurent Debelle. Elastin peptides signaling relies on neuraminidase-1-dependent lactosylceramide generation. PloS one. 2010 Nov; 5(11):e14010. doi: 10.1371/journal.pone.0014010. [PMID: 21103358]
  • Karin Ilg, Elif Yavuz, Carola Maffioli, Bernard Priem, Markus Aebi. Glycomimicry: display of the GM3 sugar epitope on Escherichia coli and Salmonella enterica sv Typhimurium. Glycobiology. 2010 Oct; 20(10):1289-97. doi: 10.1093/glycob/cwq091. [PMID: 20574043]
  • Einat B Vitner, Frances M Platt, Anthony H Futerman. Common and uncommon pathogenic cascades in lysosomal storage diseases. The Journal of biological chemistry. 2010 Jul; 285(27):20423-7. doi: 10.1074/jbc.r110.134452. [PMID: 20430897]
  • Daniel Freund, Ana-Violeta Fonseca, Peggy Janich, Martin Bornhäuser, Denis Corbeil. Differential expression of biofunctional GM1 and GM3 gangliosides within the plastic-adherent multipotent mesenchymal stromal cell population. Cytotherapy. 2010 Apr; 12(2):131-42. doi: 10.3109/14653240903476438. [PMID: 20196693]
  • Nouara Yahi, Anaïs Aulas, Jacques Fantini. How cholesterol constrains glycolipid conformation for optimal recognition of Alzheimer's beta amyloid peptide (Abeta1-40). PloS one. 2010 Feb; 5(2):e9079. doi: 10.1371/journal.pone.0009079. [PMID: 20140095]
  • Sandro Sonnino, Alessandro Prinetti. Gangliosides as regulators of cell membrane organization and functions. Advances in experimental medicine and biology. 2010; 688(?):165-84. doi: 10.1007/978-1-4419-6741-1_12. [PMID: 20919654]
  • Sandra Ristori, Emanuela Di Cola, Carlotta Lunghi, Barbara Richichi, Cristina Nativi. Structural study of liposomes loaded with a GM3 lactone analogue for the targeting of tumor epitopes. Biochimica et biophysica acta. 2009 Dec; 1788(12):2518-25. doi: 10.1016/j.bbamem.2009.10.005. [PMID: 19837046]
  • Kazutoshi Iijima, Norihiro Soga, Teruhiko Matsubara, Toshinori Sato. Observations of the distribution of GM3 in membrane microdomains by atomic force microscopy. Journal of colloid and interface science. 2009 Sep; 337(2):369-74. doi: 10.1016/j.jcis.2009.05.032. [PMID: 19524935]
  • Mirjam Langeveld, Johannes M F G Aerts. Glycosphingolipids and insulin resistance. Progress in lipid research. 2009 May; 48(3-4):196-205. doi: 10.1016/j.plipres.2009.03.002. [PMID: 19303901]
  • Patricia V Miranda, Alicia Allaire, Julian Sosnik, Pablo E Visconti. Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm. Biology of reproduction. 2009 May; 80(5):897-904. doi: 10.1095/biolreprod.108.075242. [PMID: 19144954]
  • Mari L DeMarco, Robert J Woods. Atomic-resolution conformational analysis of the GM3 ganglioside in a lipid bilayer and its implications for ganglioside-protein recognition at membrane surfaces. Glycobiology. 2009 Apr; 19(4):344-55. doi: 10.1093/glycob/cwn137. [PMID: 19056784]
  • Masanori Inagaki, Takeshi Saito, Tomofumi Miyamoto, Ryuichi Higuchi. Isolation and structure of hematoside-type ganglioside from the starfish Linckia laevigata. Chemical & pharmaceutical bulletin. 2009 Feb; 57(2):204-6. doi: 10.1248/cpb.57.204. [PMID: 19182413]
  • Yoshimi Haga, Sen-itiroh Hakomori, Kenichi Hatanaka. Quantitative analysis of EGFR affinity to immobilized glycolipids by surface plasmon resonance. Carbohydrate research. 2008 Dec; 343(18):3034-8. doi: 10.1016/j.carres.2008.09.002. [PMID: 18828994]
  • Yong Chen, Jie Qin, Zheng W Chen. Fluorescence-topographic NSOM directly visualizes peak-valley polarities of GM1/GM3 rafts in cell membrane fluctuations. Journal of lipid research. 2008 Oct; 49(10):2268-75. doi: 10.1194/jlr.d800031-jlr200. [PMID: 18603643]
  • Stéphane Woerly, Sébastien Fort, Isabelle Pignot-Paintrand, Cécile Cottet, Carole Carcenac, Marc Savasta. Development of a sialic acid-containing hydrogel of poly[N-(2-hydroxypropyl) methacrylamide]: characterization and implantation study. Biomacromolecules. 2008 Sep; 9(9):2329-37. doi: 10.1021/bm800234r. [PMID: 18715030]
  • Hao Li, Stephen D Turley, Benny Liu, Joyce J Repa, John M Dietschy. GM2/GD2 and GM3 gangliosides have no effect on cellular cholesterol pools or turnover in normal or NPC1 mice. Journal of lipid research. 2008 Aug; 49(8):1816-28. doi: 10.1194/jlr.m800180-jlr200. [PMID: 18450647]
  • Purna Mukherjee, Anthony C Faber, Laura M Shelton, Rena C Baek, Thomas C Chiles, Thomas N Seyfried. Thematic review series: sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a. Journal of lipid research. 2008 May; 49(5):929-38. doi: 10.1194/jlr.r800006-jlr200. [PMID: 18287616]
  • Karen Ghauharali-van der Vlugt, Mirjam Langeveld, Aldi Poppema, Sijmen Kuiper, Carla E M Hollak, Johannes M Aerts, Johanna E M Groener. Prominent increase in plasma ganglioside GM3 is associated with clinical manifestations of type I Gaucher disease. Clinica chimica acta; international journal of clinical chemistry. 2008 Mar; 389(1-2):109-13. doi: 10.1016/j.cca.2007.12.001. [PMID: 18164265]
  • Yoshimi Haga, Kenichi Hatanaka, Sen-itiroh Hakomori. Effect of lipid mimetics of GM3 and lyso-GM3 dimer on EGF receptor tyrosine kinase and EGF-induced signal transduction. Biochimica et biophysica acta. 2008 Mar; 1780(3):393-404. doi: 10.1016/j.bbagen.2007.10.018. [PMID: 18036568]
  • Tomohisa Kato, Atsushi Miyagawa, Maria Carmelita Z Kasuya, Ayaka Ito, Kenichi Hatanaka. Purification by centrifugal partition chromatography of amphiphilic compounds, glycolipids and pseudo-glycolipids synthesized by using cells. Journal of chromatography. A. 2008 Jan; 1178(1-2):154-9. doi: 10.1016/j.chroma.2007.11.094. [PMID: 18082172]
  • Kazuya I P J Hidari, Shizumi Shimada, Yasuo Suzuki, Takashi Suzuki. Binding kinetics of influenza viruses to sialic acid-containing carbohydrates. Glycoconjugate journal. 2007 Dec; 24(9):583-90. doi: 10.1007/s10719-007-9055-y. [PMID: 17624609]
  • Marcello Sega, Renzo Vallauri, Paola Brocca, Laura Cantù, Simone Melchionna. Short-range structure of a GM3 ganglioside membrane: comparison between experimental WAXS and computer simulation results. The journal of physical chemistry. B. 2007 Sep; 111(37):10965-9. doi: 10.1021/jp072834a. [PMID: 17718468]
  • Kazuya Kabayama, Takashige Sato, Kumiko Saito, Nicoletta Loberto, Alessandro Prinetti, Sandro Sonnino, Masataka Kinjo, Yasuyuki Igarashi, Jin-ichi Inokuchi. Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 2007 Aug; 104(34):13678-83. doi: 10.1073/pnas.0703650104. [PMID: 17699617]
  • S Roperto, G Borzacchiello, R Casellato, P Galati, V Russo, S Sonnino, F Roperto. Sialic acid and GM3 ganglioside expression in papillomavirus-associated urinary bladder tumours of cattle with chronic enzootic haematuria. Journal of comparative pathology. 2007 Aug; 137(2-3):87-93. doi: 10.1016/j.jcpa.2007.03.008. [PMID: 17624364]
  • Satoshi Uemura, Fei Feng, Maya Kume, Kuriko Yamada, Kazuya Kabayama, Shin-Ichiro Nishimura, Yasuyuki Igarashi, Jin-Ichi Inokuchi. Cell growth arrest by sialic acid clusters in ganglioside GM3 mimetic polymers. Glycobiology. 2007 Jun; 17(6):568-77. doi: 10.1093/glycob/cwm020. [PMID: 17317719]
  • Akikazu Fujita, Jinglei Cheng, Minako Hirakawa, Koichi Furukawa, Susumu Kusunoki, Toyoshi Fujimoto. Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. Molecular biology of the cell. 2007 Jun; 18(6):2112-22. doi: 10.1091/mbc.e07-01-0071. [PMID: 17392511]
  • Matthew E C Caines, Mark D Vaughan, Chris A Tarling, Susan M Hancock, R Antony J Warren, Stephen G Withers, Natalie C J Strynadka. Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms. The Journal of biological chemistry. 2007 May; 282(19):14300-8. doi: 10.1074/jbc.m611455200. [PMID: 17329247]
  • Peggy Janich, Denis Corbeil. GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells. FEBS letters. 2007 May; 581(9):1783-7. doi: 10.1016/j.febslet.2007.03.065. [PMID: 17428477]
  • Jin-ichi Inokuchi. Insulin resistance as a membrane microdomain disorder. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2007 Apr; 127(4):579-86. doi: 10.1248/yakushi.127.579. [PMID: 17409686]
  • Paul A Nuzzi, Melissa A Senetar, Anna Huttenlocher. Asymmetric localization of calpain 2 during neutrophil chemotaxis. Molecular biology of the cell. 2007 Mar; 18(3):795-805. doi: 10.1091/mbc.e06-09-0876. [PMID: 17192410]
  • Zak Martinez, Min Zhu, Shubo Han, Anthony L Fink. GM1 specifically interacts with alpha-synuclein and inhibits fibrillation. Biochemistry. 2007 Feb; 46(7):1868-77. doi: 10.1021/bi061749a. [PMID: 17253773]
  • Christine Grauby-Heywang, Jean-Marie Turlet. Study of the cholesterol-GM3 ganglioside interaction by surface pressure measurements and fluorescence microscopy. Colloids and surfaces. B, Biointerfaces. 2007 Feb; 54(2):211-6. doi: 10.1016/j.colsurfb.2006.10.025. [PMID: 17137761]
  • P H Thiesen, H Rosenfeld, P Konidala, V M Garamus, L He, A Prange, B Niemeyer. Glycolipids from a colloid chemical point of view. Journal of biotechnology. 2006 Jun; 124(1):284-301. doi: 10.1016/j.jbiotec.2006.03.032. [PMID: 16707183]
  • Rea Valaperta, Vanna Chigorno, Luisa Basso, Alessandro Prinetti, Roberto Bresciani, Augusto Preti, Taeko Miyagi, Sandro Sonnino. Plasma membrane production of ceramide from ganglioside GM3 in human fibroblasts. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2006 Jun; 20(8):1227-9. doi: 10.1096/fj.05-5077fje. [PMID: 16645048]
  • Vanna Chigorno, Mariateresa Sciannamblo, Joanna Mikulak, Alessandro Prinetti, Sandro Sonnino. Efflux of sphingolipids metabolically labeled with [1-3H]sphingosine, L-[3- 3H]serine and [9,10- 3H]palmitic acid from normal cells in culture. Glycoconjugate journal. 2006 May; 23(3-4):159-65. doi: 10.1007/s10719-006-7921-7. [PMID: 16691499]
  • Xiao-Qi Wang, Amy S Paller. Lipid rafts: membrane triage centers. The Journal of investigative dermatology. 2006 May; 126(5):951-3. doi: 10.1038/sj.jid.5700282. [PMID: 16619013]
  • Elena Sottocornola, Roberta Misasi, Vincenzo Mattei, Laura Ciarlo, Roberto Gradini, Tina Garofalo, Bruno Berra, Irma Colombo, Maurizio Sorice. Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells. The FEBS journal. 2006 Apr; 273(8):1821-30. doi: 10.1111/j.1742-4658.2006.05203.x. [PMID: 16623716]
  • Christine Grauby-Heywang, Jean-Marie Turlet. Behavior of GM3 ganglioside in lipid monolayers mimicking rafts or fluid phase in membranes. Chemistry and physics of lipids. 2006 Jan; 139(1):68-76. doi: 10.1016/j.chemphyslip.2005.10.003. [PMID: 16310758]
  • T Garofalo, A M Giammarioli, R Misasi, A Tinari, V Manganelli, L Gambardella, A Pavan, W Malorni, M Sorice. Lipid microdomains contribute to apoptosis-associated modifications of mitochondria in T cells. Cell death and differentiation. 2005 Nov; 12(11):1378-89. doi: 10.1038/sj.cdd.4401672. [PMID: 15947792]
  • Toshiyuki Hikita, Keiko Tadano-Aritomi, Naoko Iida-Tanaka, Ineo Ishizuka, Senitiroh Hakomori. De-N-acetyllactotriaosylceramide as a novel cationic glycosphingolipid of bovine brain white matter: isolation and characterization. Biochemistry. 2005 Jul; 44(27):9555-62. doi: 10.1021/bi0504411. [PMID: 15996110]