SKF-96365 free base (BioDeep_00000844546)
代谢物信息卡片
SKF-96365 free base
化学式: C22H26N2O3 (366.1943)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC=C(C=C1)CCCOC(CN2C=CN=C2)C3=CC=C(C=C3)OC
InChI: InChI=1S/C22H26N2O3/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19/h5-14,17,22H,3-4,15-16H2,1-2H3
描述信息
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers
D000077264 - Calcium-Regulating Hormones and Agents
D049990 - Membrane Transport Modulators
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:145122
- ChEBI: CHEBI:91847
- PubChem: 104956
- ChEMBL: CHEMBL258502
- CAS: 162849-90-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Yingjun Zang, Shuang Liu, Aili Cao, Xiangyu Shan, Wenjuan Deng, Zhijun Li, Hao Wang, Yunman Wang, Li Wang, Wen Peng. Astragaloside IV inhibits palmitic acid-induced apoptosis through regulation of calcium homeostasis in mice podocytes.
Molecular biology reports.
2021 Feb; 48(2):1453-1464. doi:
10.1007/s11033-021-06204-4. [PMID: 33606151] - Guangyi Ba, Ru Tang, Xiwen Sun, Zhipeng Li, Hai Lin, Weitian Zhang. Therapeutic effects of SKF-96365 on murine allergic rhinitis induced by OVA.
International journal of immunopathology and pharmacology.
2021 Jan; 35(?):20587384211015054. doi:
10.1177/20587384211015054. [PMID: 33983057] - Jinrui Xu, Yuquan Yang, Zhaoyuan Hou, Hao Jia, Yujiong Wang. TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions.
Theranostics.
2021; 11(15):7379-7390. doi:
10.7150/thno.58781. [PMID: 34158856] - Akshaya Chandrasekaran, May Y Lee, Xuexin Zhang, Shaheen Hasan, Habben Desta, Scott A Tenenbaum, J Andrés Melendez. Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype.
Experimental biology and medicine (Maywood, N.J.).
2020 11; 245(17):1560-1570. doi:
10.1177/1535370220943122. [PMID: 32686475] - Joanna Gruszczynska-Biegala, Klaudia Strucinska, Filip Maciag, Lukasz Majewski, Maria Sladowska, Jacek Kuznicki. STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons.
Cells.
2020 01; 9(1):. doi:
10.3390/cells9010160. [PMID: 31936514] - Ching-Ying Wu, Wen-Li Hsu, Ming-Hsien Tsai, Chee-Yin Chai, Chia-Jung Yen, Chu-Huang Chen, Jian-He Lu, Hsin-Su Yu, Tohru Yoshioka. A potential new approach for treating systemic sclerosis: Dedifferentiation of SSc fibroblasts and change in the microenvironment by blocking store-operated Ca2+ entry.
PloS one.
2019; 14(3):e0213400. doi:
10.1371/journal.pone.0213400. [PMID: 30870448] - Cinthia L Dionicio, Franshelle Peña, Luis A Constantino-Jonapa, Carlos Vazquez, Martha Yocupicio-Monroy, Romel Rosales, José Luis Zambrano, Marie Christine Ruiz, Rosa M Del Angel, Juan E Ludert. Dengue virus induced changes in Ca2+ homeostasis in human hepatic cells that favor the viral replicative cycle.
Virus research.
2018 02; 245(?):17-28. doi:
10.1016/j.virusres.2017.11.029. [PMID: 29269104] - Jin-Nan Zhong, Lan Lan, Yi-Fei Chen, Ge Huang, Guang-Zhen He, Jiong Yang, Ya-Dong Gao. IL-4 and serum amyloid P inversely regulate fibrocyte differentiation by targeting store-operated Ca2+ channels.
Pharmacological reports : PR.
2018 Feb; 70(1):22-28. doi:
10.1016/j.pharep.2017.07.005. [PMID: 29306759] - Wei Wang, Yuyue Ren, Lianjie Wang, Weiwei Zhao, Xiushuai Dong, Jiaqi Pan, Haiyan Gao, Yaoyao Tian. Orai1 and Stim1 Mediate the Majority of Store-Operated Calcium Entry in Multiple Myeloma and Have Strong Implications for Adverse Prognosis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2018; 48(6):2273-2285. doi:
10.1159/000492645. [PMID: 30114708] - Xu-Guang Jia, Meng-Xiao Zheng, Jing-Jing Zhang, Cong-Cong Zhang, Mei-Ping Zhao, Yi-Ming Wu, Xi-Wen Chen, Wan-Tie Wang. [Role of TRPC6 in pulmonary artery smooth muscle cells proliferation and apoptosis under hypoxia and hypercapnia].
Sheng li xue bao : [Acta physiologica Sinica].
2017 Feb; 69(1):47-54. doi:
. [PMID: 28217807] - Xiaoyi Mai, Jinyan Shang, Sijia Liang, Beixin Yu, Jiani Yuan, Yu Lin, Renfei Luo, Feiran Zhang, Yingying Liu, Xiaofei Lv, Chunling Li, Xinling Liang, Weidong Wang, Jiaguo Zhou. Blockade of Orai1 Store-Operated Calcium Entry Protects against Renal Fibrosis.
Journal of the American Society of Nephrology : JASN.
2016 Oct; 27(10):3063-3078. doi:
10.1681/asn.2015080889. [PMID: 26940090] - Oleksandra Tiapko, Bernadett Bacsa, Gema Guedes de la Cruz, Toma Glasnov, Klaus Groschner. Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect.
Science China. Life sciences.
2016 Aug; 59(8):802-10. doi:
10.1007/s11427-016-5095-5. [PMID: 27430887] - Jessica Sabourin, Fiona Bartoli, Fabrice Antigny, Ana Maria Gomez, Jean-Pierre Benitah. Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca2+ Channels: NEW TARGETS OF ALDOSTERONE IN CARDIOMYOCYTES.
The Journal of biological chemistry.
2016 Jun; 291(25):13394-409. doi:
10.1074/jbc.m115.693911. [PMID: 27129253] - Shota Sasaki, Makoto Kanzaki, Toshiro Kaneko. Calcium influx through TRP channels induced by short-lived reactive species in plasma-irradiated solution.
Scientific reports.
2016 05; 6(?):25728. doi:
10.1038/srep25728. [PMID: 27169489] - BingBing Shen, Yue He, Shan Zhou, Hongwen Zhao, Mei Mei, Xiongfei Wu. TRPC6 May Protect Renal Ischemia-Reperfusion Injury Through Inhibiting Necroptosis of Renal Tubular Epithelial Cells.
Medical science monitor : international medical journal of experimental and clinical research.
2016 Feb; 22(?):633-41. doi:
10.12659/msm.897353. [PMID: 26913924] - Ching-Ying Wu, Wen-Li Hsu, Chun-Hsiung Wang, Jui-Lin Liang, Ming-Hsien Tsai, Chia-Jung Yen, Hsiu-Wen Li, Siou-Jin Chiu, Chung-Hsing Chang, Yaw-Bin Huang, Ming-Wei Lin, Tohru Yoshioka. A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages.
PloS one.
2016; 11(7):e0159299. doi:
10.1371/journal.pone.0159299. [PMID: 27472555] - Zhaowei Liu, Jiajia Yang, Xiaochen Zhang, Pengjuan Xu, Tao Zhang, Zhuo Yang. Developmental changes in the expression and function of TRPC6 channels related the F-actin organization during differentiation in podocytes.
Cell calcium.
2015 Dec; 58(6):541-8. doi:
10.1016/j.ceca.2015.09.001. [PMID: 26363733] - H-H Cheng, C-T Chou, T-K Sun, W-Z Liang, J-S Cheng, H-T Chang, H-W Tseng, C-C Kuo, F-A Chen, D-H Kuo, P Shieh, C-R Jan. Naproxen-induced Ca2+ movement and death in MDCK canine renal tubular cells.
Human & experimental toxicology.
2015 Nov; 34(11):1096-105. doi:
10.1177/0960327115569810. [PMID: 25636639] - Felix Kurth, Alfredo Franco-Obregón, Marco Casarosa, Simon K Küster, Karin Wuertz-Kozak, Petra S Dittrich. Transient receptor potential vanilloid 2-mediated shear-stress responses in C2C12 myoblasts are regulated by serum and extracellular matrix.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2015 Nov; 29(11):4726-37. doi:
10.1096/fj.15-275396. [PMID: 26207028] - Samira Samtleben, Britta Wachter, Robert Blum. Store-operated calcium entry compensates fast ER calcium loss in resting hippocampal neurons.
Cell calcium.
2015 Aug; 58(2):147-59. doi:
10.1016/j.ceca.2015.04.002. [PMID: 25957620] - P Sukumaran, Y Sun, M Vyas, B B Singh. TRPC1-mediated Ca²⁺ entry is essential for the regulation of hypoxia and nutrient depletion-dependent autophagy.
Cell death & disease.
2015 Mar; 6(?):e1674. doi:
10.1038/cddis.2015.7. [PMID: 25741599] - Shihao Tang, Xubu Wang, Qiang Shen, Xinyi Yang, Changhui Yu, Chunqing Cai, Guoshuai Cai, Xiaojing Meng, Fei Zou. Mitochondrial Ca²⁺ uniporter is critical for store-operated Ca²⁺ entry-dependent breast cancer cell migration.
Biochemical and biophysical research communications.
2015 Feb; 458(1):186-93. doi:
10.1016/j.bbrc.2015.01.092. [PMID: 25640838] - Jianwei Sun, Fujian Lu, Huifang He, Junling Shen, Jane Messina, Rahel Mathew, Dapeng Wang, Amod A Sarnaik, Wei-Chiao Chang, Minjung Kim, Heping Cheng, Shengyu Yang. STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion.
The Journal of cell biology.
2014 Nov; 207(4):535-48. doi:
10.1083/jcb.201407082. [PMID: 25404747] - Daria V Ilatovskaya, Oleg Palygin, Vladislav Chubinskiy-Nadezhdin, Yuri A Negulyaev, Rong Ma, Lutz Birnbaumer, Alexander Staruschenko. Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli.
Kidney international.
2014 Sep; 86(3):506-14. doi:
10.1038/ki.2014.71. [PMID: 24646854] - Jasmin Lalonde, Gregory Saia, Grace Gill. Store-operated calcium entry promotes the degradation of the transcription factor Sp4 in resting neurons.
Science signaling.
2014 Jun; 7(328):ra51. doi:
10.1126/scisignal.2005242. [PMID: 24894994] - Marc Anderson, Hila Roshanravan, Justin Khine, Stuart E Dryer. Angiotensin II activation of TRPC6 channels in rat podocytes requires generation of reactive oxygen species.
Journal of cellular physiology.
2014 Apr; 229(4):434-42. doi:
10.1002/jcp.24461. [PMID: 24037962] - Marc Anderson, Eun Young Kim, Henning Hagmann, Thomas Benzing, Stuart E Dryer. Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol.
American journal of physiology. Cell physiology.
2013 Aug; 305(3):C276-89. doi:
10.1152/ajpcell.00095.2013. [PMID: 23657570] - Ying-Ting Chen, Yih-Fung Chen, Wen-Tai Chiu, Yang-Kao Wang, Hsien-Chang Chang, Meng-Ru Shen. The ER Ca²⁺ sensor STIM1 regulates actomyosin contractility of migratory cells.
Journal of cell science.
2013 Mar; 126(Pt 5):1260-7. doi:
10.1242/jcs.121129. [PMID: 23378028] - I S Chen, K T Mok, C T Chou, S I Liu, C C Kuo, S S Hsu, H T Chang, J Y Tsai, W C Liao, C R Jan. Effect of phenethyl isothiocyanate on Ca2+ movement and viability in MDCK canine renal tubular cells.
Human & experimental toxicology.
2012 Dec; 31(12):1251-61. doi:
10.1177/0960327112446841. [PMID: 22653687] - Jung-Nien Lai, Olivia Ya-Hsuan Wang, Veronica Hui-Chen Lin, Ching-Fong Liao, Der-Cherng Tarng, Eileen Jea Chien. The non-genomic rapid acidification in peripheral T cells by progesterone depends on intracellular calcium increase and not on Na+/H+-exchange inhibition.
Steroids.
2012 Aug; 77(10):1017-24. doi:
10.1016/j.steroids.2012.03.004. [PMID: 22449718] - Mikio Marumo, Tomoyuki Nakano, Yuji Takeda, Kaoru Goto, Ichiro Wakabayashi. Inhibition of thrombin-induced Ca²⁺ influx in platelets by R59949, an inhibitor of diacylglycerol kinase.
The Journal of pharmacy and pharmacology.
2012 Jun; 64(6):855-61. doi:
10.1111/j.2042-7158.2012.01485.x. [PMID: 22571264] - Maoquan Li, Chunhai Chen, Zhou Zhou, Shangcheng Xu, Zhengping Yu. A TRPC1-mediated increase in store-operated Ca2+ entry is required for the proliferation of adult hippocampal neural progenitor cells.
Cell calcium.
2012 Jun; 51(6):486-96. doi:
10.1016/j.ceca.2012.04.014. [PMID: 22579301] - Eun Young Kim, Marc Anderson, Stuart E Dryer. Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.
American journal of physiology. Renal physiology.
2012 Feb; 302(3):F298-307. doi:
10.1152/ajprenal.00423.2011. [PMID: 22031853] - Michelle D Amaral, Lucas Pozzo-Miller. Intracellular Ca2+ stores and Ca2+ influx are both required for BDNF to rapidly increase quantal vesicular transmitter release.
Neural plasticity.
2012; 2012(?):203536. doi:
10.1155/2012/203536. [PMID: 22811938] - Paul E Wolkowicz, Jian Huang, Patrick K Umeda, Oleg F Sharifov, Edlue Tabengwa, Brian A Halloran, Ferdinand Urthaler, Hernan E Grenett. Pharmacological evidence for Orai channel activation as a source of cardiac abnormal automaticity.
European journal of pharmacology.
2011 Oct; 668(1-2):208-16. doi:
10.1016/j.ejphar.2011.06.025. [PMID: 21745466] - Paolo Ariano, Simona Dalmazzo, Grzegorz Owsianik, Bernd Nilius, Davide Lovisolo. TRPC channels are involved in calcium-dependent migration and proliferation in immortalized GnRH neurons.
Cell calcium.
2011 Jun; 49(6):387-94. doi:
10.1016/j.ceca.2011.03.007. [PMID: 21511334] - Ningren Cui, Xiaoli Zhang, Jyothirmayee S Tadepalli, Lei Yu, Hongyu Gai, James Petit, Ravi T Pamulapati, Xin Jin, Chun Jiang. Involvement of TRP channels in the CO₂ chemosensitivity of locus coeruleus neurons.
Journal of neurophysiology.
2011 Jun; 105(6):2791-801. doi:
10.1152/jn.00759.2010. [PMID: 21430274] - Kay-Pong Yip, James S K Sham. Mechanisms of vasopressin-induced intracellular Ca2+ oscillations in rat inner medullary collecting duct.
American journal of physiology. Renal physiology.
2011 Feb; 300(2):F540-8. doi:
10.1152/ajprenal.00544.2009. [PMID: 21147839] - M Salomonsson, T H Braunstein, N-H Holstein-Rathlou, L J Jensen. Na+-independent, nifedipine-resistant rat afferent arteriolar Ca2+ responses to noradrenaline: possible role of TRPC channels.
Acta physiologica (Oxford, England).
2010 Nov; 200(3):265-78. doi:
10.1111/j.1748-1716.2010.02141.x. [PMID: 20426773] - A Singh, M E Hildebrand, E Garcia, T P Snutch. The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels.
British journal of pharmacology.
2010 Jul; 160(6):1464-75. doi:
10.1111/j.1476-5381.2010.00786.x. [PMID: 20590636] - Kali Hicks, Roger G O'Neil, William S Dubinsky, Rachel C Brown. TRPC-mediated actin-myosin contraction is critical for BBB disruption following hypoxic stress.
American journal of physiology. Cell physiology.
2010 Jun; 298(6):C1583-93. doi:
10.1152/ajpcell.00458.2009. [PMID: 20164382] - Yi-hua Sun, Yong-quan Li, Shan-li Feng, Bao-xin Li, Zhen-wei Pan, Chang-qing Xu, Ting-ting Li, Bao-feng Yang. Calcium-sensing receptor activation contributed to apoptosis stimulates TRPC6 channel in rat neonatal ventricular myocytes.
Biochemical and biophysical research communications.
2010 Apr; 394(4):955-61. doi:
10.1016/j.bbrc.2010.03.096. [PMID: 20307499] - Kumiko Yamaoka, Akiko Yano, Kenji Kuroiwa, Kazushi Morimoto, Tomoaki Inazumi, Noriyuki Hatae, Hiroyuki Tabata, Eri Segi-Nishida, Satoshi Tanaka, Atsushi Ichikawa, Yukihiko Sugimoto. Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner.
Biochemical and biophysical research communications.
2009 Nov; 389(4):678-82. doi:
10.1016/j.bbrc.2009.09.064. [PMID: 19769944] - Tanja Kirchberger, Christelle Moreau, Gerd K Wagner, Ralf Fliegert, Cornelia C Siebrands, Merle Nebel, Frederike Schmid, Angelika Harneit, Francesca Odoardi, Alexander Flügel, Barry V L Potter, Andreas H Guse. 8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist.
The Biochemical journal.
2009 Jul; 422(1):139-49. doi:
10.1042/bj20082308. [PMID: 19492987] - Eva Schepers, Griet Glorieux, Annemieke Dhondt, Luc Leybaert, Raymond Vanholder. Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2009 May; 24(5):1429-35. doi:
10.1093/ndt/gfn670. [PMID: 19059932] - Peng Tu, Christiane Kunert-Keil, Silke Lucke, Heinrich Brinkmeier, Alexandre Bouron. Diacylglycerol analogues activate second messenger-operated calcium channels exhibiting TRPC-like properties in cortical neurons.
Journal of neurochemistry.
2009 Jan; 108(1):126-38. doi:
10.1111/j.1471-4159.2008.05752.x. [PMID: 19094061] - F Ardón, E Rodríguez-Miranda, C Beltrán, A Hernández-Cruz, A Darszon. Mitochondrial inhibitors activate influx of external Ca(2+) in sea urchin sperm.
Biochimica et biophysica acta.
2009 Jan; 1787(1):15-24. doi:
10.1016/j.bbabio.2008.10.003. [PMID: 19000650] - Ian Daniels, Julie Turzanski, Andrew P Haynes. A requirement for calcium in the caspase-independent killing of Burkitt lymphoma cell lines by Rituximab.
British journal of haematology.
2008 Jul; 142(3):394-403. doi:
10.1111/j.1365-2141.2008.07193.x. [PMID: 18544085] - Neta Rimmerman, Heather B Bradshaw, H Velocity Hughes, Jay Shih-Chieh Chen, Sherry Shu-Jung Hu, Douglas McHugh, Eivind Vefring, Jan A Jahnsen, Eric L Thompson, Kim Masuda, Benjamin F Cravatt, Sumner Burstein, Michael R Vasko, Anne L Prieto, David K O'Dell, J Michael Walker. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons.
Molecular pharmacology.
2008 Jul; 74(1):213-24. doi:
10.1124/mol.108.045997. [PMID: 18424551] - G Aguiari, V Trimi, M Bogo, A Mangolini, G Szabadkai, P Pinton, R Witzgall, P C Harris, P A Borea, R Rizzuto, L del Senno. Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells.
Cell proliferation.
2008 Jun; 41(3):554-73. doi:
10.1111/j.1365-2184.2008.00529.x. [PMID: 18422703] - Ronald M Lynch, Craig S Weber, Kevin D Nullmeyer, Edwin D W Moore, Richard J Paul. Clearance of store-released Ca2+ by the Na+-Ca2+ exchanger is diminished in aortic smooth muscle from Na+-K+-ATPase alpha 2-isoform gene-ablated mice.
American journal of physiology. Heart and circulatory physiology.
2008 Mar; 294(3):H1407-16. doi:
10.1152/ajpheart.00855.2007. [PMID: 18192219] - D Labelle, C Jumarie, R Moreau. Capacitative calcium entry and proliferation of human osteoblast-like MG-63 cells.
Cell proliferation.
2007 Dec; 40(6):866-84. doi:
10.1111/j.1365-2184.2007.00477.x. [PMID: 18021176] - Yichang Jia, Jian Zhou, Yilin Tai, Yizheng Wang. TRPC channels promote cerebellar granule neuron survival.
Nature neuroscience.
2007 May; 10(5):559-67. doi:
10.1038/nn1870. [PMID: 17396124] - Min Wang, Riccardo Bianchi, Shih-Chieh Chuang, Wangfa Zhao, Robert K S Wong. Group I metabotropic glutamate receptor-dependent TRPC channel trafficking in hippocampal neurons.
Journal of neurochemistry.
2007 Apr; 101(2):411-21. doi:
10.1111/j.1471-4159.2006.04377.x. [PMID: 17402970] - Octavio Pernas-Sueiras, Amparo Alfonso, Mercedes R Vieytes, Alberto Orfao, Luis Escribano, Sánchez-Jiménez Francisca, Luis M Botana. Calcium-pH crosstalks in the human mast cell line HMC-1: intracellular alkalinization activates calcium extrusion through the plasma membrane Ca2+-ATPase.
Journal of cellular biochemistry.
2006 Dec; 99(5):1397-408. doi:
10.1002/jcb.21010. [PMID: 16817237] - Da-nian Nie, Song-mei Yin, Shuang-feng Xie. [Experimental study on anti-platelet effects of ginsenoside -2A in vitro].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2006 Jun; 26 Suppl(?):83-5. doi:
NULL. [PMID: 17569356] - Mark E Hansen, Isaac N Pessah, Fumio Matsumura. Heptachlor epoxide induces a non-capacitative type of Ca2+ entry and immediate early gene expression in mouse hepatoma cells.
Toxicology.
2006 Mar; 220(2-3):218-31. doi:
10.1016/j.tox.2006.01.006. [PMID: 16469423] - Bruna Pelucchi, Gianluca Aguiari, Angela Pignatelli, Elisa Manzati, Ralph Witzgall, Laura Del Senno, Ottorino Belluzzi. Nonspecific cation current associated with native polycystin-2 in HEK-293 cells.
Journal of the American Society of Nephrology : JASN.
2006 Feb; 17(2):388-97. doi:
10.1681/asn.2004121146. [PMID: 16396967] - Nidhal Ben-Amor, Pedro C Redondo, Aghleb Bartegi, José A Pariente, Ginés M Salido, Juan A Rosado. A role for 5,6-epoxyeicosatrienoic acid in calcium entry by de novo conformational coupling in human platelets.
The Journal of physiology.
2006 Jan; 570(Pt 2):309-23. doi:
10.1113/jphysiol.2005.100800. [PMID: 16308346] - Jih-Pyang Wang, Chia-Shun Tseng, Shu-Ping Sun, Yu-San Chen, Chi-Ren Tsai, Mei-Feng Hsu. Capsaicin stimulates the non-store-operated Ca2+ entry but inhibits the store-operated Ca2+ entry in neutrophils.
Toxicology and applied pharmacology.
2005 Dec; 209(2):134-44. doi:
10.1016/j.taap.2005.04.002. [PMID: 15882882] - Daoyan Liu, Alexandra Scholze, Zhiming Zhu, Reinhold Kreutz, Markus Wehland-von-Trebra, Walter Zidek, Martin Tepel. Increased transient receptor potential channel TRPC3 expression in spontaneously hypertensive rats.
American journal of hypertension.
2005 Nov; 18(11):1503-7. doi:
10.1016/j.amjhyper.2005.05.033. [PMID: 16280289] - Jih-Pyang Wang, Jaw-Ji Tsai, Yu-San Chen, Mei-Feng Hsu. Stimulation of intracellular Ca2+ elevation in neutrophils by thiol-oxidizing phenylarsine oxide.
Biochemical pharmacology.
2005 Apr; 69(8):1225-34. doi:
10.1016/j.bcp.2005.01.013. [PMID: 15794943] - Shunichi Kajioka, Shinsuke Nakayama, Haruhiko Asano, Alison F Brading. Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle.
American journal of physiology. Cell physiology.
2005 Jan; 288(1):C100-8. doi:
10.1152/ajpcell.00161.2004. [PMID: 15317662] - Jih-Pyang Wang, Mei-Feng Hsu, Horng-Huey Ko, Chun-Nan Lin. Stimulation of cellular free Ca2+ elevation and inhibition of store-operated Ca2+ entry by kazinol B in neutrophils.
Naunyn-Schmiedeberg's archives of pharmacology.
2004 Dec; 370(6):500-9. doi:
10.1007/s00210-004-0997-3. [PMID: 15558242] - Alan Sabirsh, Jesper Bristulf, Christer Owman. Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2.
European journal of pharmacology.
2004 Sep; 499(1-2):53-65. doi:
10.1016/j.ejphar.2004.07.060. [PMID: 15363951] - Ronald J Knox, Neil S Magoski, David Wing, Steven J Barbee, Leonard K Kaczmarek. Activation of a calcium entry pathway by sodium pyrithione in the bag cell neurons of Aplysia.
Journal of neurobiology.
2004 Sep; 60(4):411-23. doi:
10.1002/neu.20029. [PMID: 15307146] - S V Mikhutkina, A B Salmina, A V Sychev, Yu A Uspenskaya, L V Trufanova, E I Taksanova, R Ya Olovyannikova. Blebbing of thymocyte plasma membrane and apoptosis are related to impairment of capacitance Ca2+ entry into cells.
Bulletin of experimental biology and medicine.
2004 Jun; 137(6):551-5. doi:
10.1023/b:bebm.0000042709.57599.67. [PMID: 15455082] - Yi Pang, Pam Bounelis, John C Chatham, Richard B Marchase. Hexosamine pathway is responsible for inhibition by diabetes of phenylephrine-induced inotropy.
Diabetes.
2004 Apr; 53(4):1074-81. doi:
10.2337/diabetes.53.4.1074. [PMID: 15047624] - Masahiro Matsubara, Shigehiro Masaki, Kenji Ohmori, Akira Karasawa, Kazuhide Hasegawa. Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells.
Biochemical pharmacology.
2004 Apr; 67(7):1315-26. doi:
10.1016/j.bcp.2003.12.008. [PMID: 15013847] - Yaxiong Yang, Gregory A Kinney, William J Spain, John C S Breitner, David G Cook. Presenilin-1 and intracellular calcium stores regulate neuronal glutamate uptake.
Journal of neurochemistry.
2004 Mar; 88(6):1361-72. doi:
10.1046/j.1471-4159.2003.02279.x. [PMID: 15009636] - C A Bertrand, H Danahay, C T Poll, C Laboisse, U Hopfer, R J Bridges. Niflumic acid inhibits ATP-stimulated exocytosis in a mucin-secreting epithelial cell line.
American journal of physiology. Cell physiology.
2004 Feb; 286(2):C247-55. doi:
10.1152/ajpcell.00593.2002. [PMID: 14522823] - Mark E Boston, G Christopher Frech, Enrique Chacon-Cruz, E Stephen Buescher, David G Oelberg. Surfactant releases internal calcium stores in neutrophils by G protein-activated pathway.
Experimental biology and medicine (Maywood, N.J.).
2004 Jan; 229(1):99-107. doi:
10.1177/153537020422900112. [PMID: 14709782] - Kazuhiko Seya, Ken-Ichi Furukawa, Satoshi Taniguchi, Genji Kodzuka, Yoshiteru Oshima, Masatake Niwa, Shigeru Motomura. Endothelium-dependent vasodilatory effect of vitisin C, a novel plant oligostilbene from Vitis plants (Vitaceae), in rabbit aorta.
Clinical science (London, England : 1979).
2003 Jul; 105(1):73-9. doi:
10.1042/cs20020288. [PMID: 12605596] - Hyun-Sook Kim, Fumikazu Okajima, Dong-Soon Im. Analysis of vasopressin-induced Ca2+ increase in rat hepatocytes.
Archives of pharmacal research.
2003 Jan; 26(1):64-9. doi:
10.1007/bf03179934. [PMID: 12568361] - Tsuneo Takenaka, Hiromichi Suzuki, Hirokazu Okada, Tsutomu Inoue, Yoshihiko Kanno, Yuri Ozawa, Koichi Hayashi, Takao Saruta. Transient receptor potential channels in rat renal microcirculation: actions of angiotensin II.
Kidney international.
2002 Aug; 62(2):558-65. doi:
10.1046/j.1523-1755.2002.00484.x. [PMID: 12110018] - Alessandra Gamberucci, Emanuele Giurisato, Paola Pizzo, Maristella Tassi, Roberta Giunti, Deirdre Patricia McIntosh, Angelo Benedetti. Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products.
The Biochemical journal.
2002 May; 364(Pt 1):245-54. doi:
10.1042/bj3640245. [PMID: 11988098] - Antonio Riccio, Cesar Mattei, Rosemary E Kelsell, Andrew D Medhurst, Andrew R Calver, Andrew D Randall, John B Davis, Christopher D Benham, Menelas N Pangalos. Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx.
The Journal of biological chemistry.
2002 Apr; 277(14):12302-9. doi:
10.1074/jbc.m112313200. [PMID: 11805119] - Karen E Smith, Chen Gu, Kent A Fagan, Biao Hu, Dermot M F Cooper. Residence of adenylyl cyclase type 8 in caveolae is necessary but not sufficient for regulation by capacitative Ca(2+) entry.
The Journal of biological chemistry.
2002 Feb; 277(8):6025-31. doi:
10.1074/jbc.m109615200. [PMID: 11744699] - Silke Jung, Rainer Strotmann, Günter Schultz, Tim D Plant. TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells.
American journal of physiology. Cell physiology.
2002 Feb; 282(2):C347-59. doi:
10.1152/ajpcell.00283.2001. [PMID: 11788346] - K Boels, G Glassmeier, D Herrmann, I B Riedel, W Hampe, I Kojima, J R Schwarz, H C Schaller. The neuropeptide head activator induces activation and translocation of the growth-factor-regulated Ca(2+)-permeable channel GRC.
Journal of cell science.
2001 Oct; 114(Pt 20):3599-606. doi:
10.1242/jcs.114.20.3599. [PMID: 11707512] - K Dreja, A Bergdahl, P Hellstrand. Increased store-operated Ca2+ entry into contractile vascular smooth muscle following organ culture.
Journal of vascular research.
2001 Jul; 38(4):324-31. doi:
10.1159/000051063. [PMID: 11455203] - S F Mahmoud, C Fewtrell. Microdomains of high calcium are not required for exocytosis in RBL-2H3 mucosal mast cells.
The Journal of cell biology.
2001 Apr; 153(2):339-49. doi:
10.1083/jcb.153.2.339. [PMID: 11309415] - C Kunzelmann-Marche, J M Freyssinet, M C Martínez. Regulation of phosphatidylserine transbilayer redistribution by store-operated Ca2+ entry: role of actin cytoskeleton.
The Journal of biological chemistry.
2001 Feb; 276(7):5134-9. doi:
10.1074/jbc.m007924200. [PMID: 11076944] - V A Golovina, O Platoshyn, C L Bailey, J Wang, A Limsuwan, M Sweeney, L J Rubin, J X Yuan. Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation.
American journal of physiology. Heart and circulatory physiology.
2001 Feb; 280(2):H746-55. doi:
10.1152/ajpheart.2001.280.2.h746. [PMID: 11158974] - M C Martínez, J M Freyssinet. Deciphering the plasma membrane hallmarks of apoptotic cells: phosphatidylserine transverse redistribution and calcium entry.
BMC cell biology.
2001; 2(?):20. doi:
10.1186/1471-2121-2-20. [PMID: 11701087] - C R Halaszovich, C Zitt, E Jungling, A Luckhoff. Inhibition of TRP3 channels by lanthanides. Block from the cytosolic side of the plasma membrane.
The Journal of biological chemistry.
2000 Dec; 275(48):37423-8. doi:
10.1074/jbc.m007010200. [PMID: 10970899] - H Tinel, H W Denker, M Thie. Calcium influx in human uterine epithelial RL95-2 cells triggers adhesiveness for trophoblast-like cells. Model studies on signalling events during embryo implantation.
Molecular human reproduction.
2000 Dec; 6(12):1119-30. doi:
10.1093/molehr/6.12.1119. [PMID: 11101695] - K Uchida, K Saito, T Kitajima, Y Kamikawa. Effects of Ba2+ on F&F 96365-sensitive sustained contraction of rat pulmonary artery.
The Journal of pharmacy and pharmacology.
2000 Dec; 52(12):1513-8. doi:
10.1211/0022357001777559. [PMID: 11197080] - T M Mamic, N A Holman, S J Roberts-Thomson, G R Monteith. PMCA1 mRNA expression in rat aortic myocytes: a real-time RT-PCR study.
Biochemical and biophysical research communications.
2000 Oct; 276(3):1024-7. doi:
10.1006/bbrc.2000.3578. [PMID: 11027585] - P D Marley, P J Bales, M Zerbes, D A Powis, M O'Farrell. Mobilizing store Ca(2+) in the presence of La(3+) evokes exocytosis in bovine chromaffin cells.
Journal of neurochemistry.
2000 Sep; 75(3):1162-71. doi:
10.1046/j.1471-4159.2000.0751162.x. [PMID: 10936199] - S S Williams, J N French, M Gilbert, A A Rangaswami, J Walleczek, S J Knox. Bcl-2 overexpression results in enhanced capacitative calcium entry and resistance to SKF-96365-induced apoptosis.
Cancer research.
2000 Aug; 60(16):4358-61. doi:
NULL. [PMID: 10969777] - Y Tanaka, T Imai, T Igarashi, K Takayanagi, K Otsuka, F Yamaki, H Tanaka, K Shigenobu. Comparison of the Ca2+ entry channels responsible for mechanical responses of guinea-pig aorta to noradrenaline and thapsigargin using SK&F 96365 and LOE 908.
Naunyn-Schmiedeberg's archives of pharmacology.
2000 Aug; 362(2):160-8. doi:
10.1007/s002100000272. [PMID: 10961379] - J Kawasaki, K Hirano, M Hirano, J Nishimura, A Nakatsuka, M Fujishima, H Kanaide. Dissociation between the Ca(2+) signal and tube formation induced by vascular endothelial growth factor in bovine aortic endothelial cells.
European journal of pharmacology.
2000 Jun; 398(1):19-29. doi:
10.1016/s0014-2999(00)00296-x. [PMID: 10856444] - S Jenner, S O Sage. Two pathways for store-mediated calcium entry in human platelets.
Platelets.
2000 Jun; 11(4):215-21. doi:
10.1080/09537100050057657. [PMID: 10938900] - A L Hsu, T T Ching, G Sen, D S Wang, S Bondada, K S Authi, C S Chen. Novel function of phosphoinositide 3-kinase in T cell Ca2+ signaling. A phosphatidylinositol 3,4,5-trisphosphate-mediated Ca2+ entry mechanism.
The Journal of biological chemistry.
2000 May; 275(21):16242-50. doi:
10.1074/jbc.m002077200. [PMID: 10748064] - L Olivi, J Bressler. Maitotoxin stimulates Cd influx in Madin-Darby kidney cells by activating Ca-permeable cation channels.
Cell calcium.
2000 Apr; 27(4):187-93. doi:
10.1054/ceca.1999.0115. [PMID: 10858664] - T Okada, R Inoue, K Yamazaki, A Maeda, T Kurosaki, T Yamakuni, I Tanaka, S Shimizu, K Ikenaka, K Imoto, Y Mori. Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor.
The Journal of biological chemistry.
1999 Sep; 274(39):27359-70. doi:
10.1074/jbc.274.39.27359. [PMID: 10488066] - H Taniguchi, Y Tanaka, H Hirano, H Tanaka, K Shigenobu. Evidence for a contribution of store-operated Ca2+ channels to NO-mediated endothelium-dependent relaxation of guinea-pig aorta in response to a Ca2+ ionophore, A23187.
Naunyn-Schmiedeberg's archives of pharmacology.
1999 Jul; 360(1):69-79. doi:
10.1007/s002109900033. [PMID: 10463336] - K Törnquist, P Vainio, A Titievsky, B Dugué, R Tuominen. Redox modulation of intracellular free calcium concentration in thyroid FRTL-5 cells: evidence for an enhanced extrusion of calcium.
The Biochemical journal.
1999 May; 339 ( Pt 3)(?):621-8. doi:
10.1042/bj3390621. [PMID: 10215601]
