Androstane-3,17-dione (BioDeep_00000844529)
代谢物信息卡片
化学式: C19H28O2 (288.2089188)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCC(=O)CC1CCC3C2CCC4(C3CCC4=O)C
InChI: InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-16H,3-11H2,1-2H3/t12?,14-,15-,16-,18-,19-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
An androstanoid that is androstane substituted by oxo groups at positions 3 and 17.
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Monica Mazzarino, Maria Gabriella Abate, Roberto Alocci, Francesca Rossi, Raffaella Stinchelli, Francesco Molaioni, Xavier de la Torre, Francesco Botrè. Urine stability and steroid profile: towards a screening index of urine sample degradation for anti-doping purpose.
Analytica chimica acta.
2011 Jan; 683(2):221-6. doi:
10.1016/j.aca.2010.10.003. [PMID: 21167974] - Baerbel U Panter, Joachim Jose, Rolf W Hartmann. 5alpha-reductase in human embryonic kidney cell line HEK293: evidence for type II enzyme expression and activity.
Molecular and cellular biochemistry.
2005 Feb; 270(1-2):201-8. doi:
10.1007/s11010-005-4508-8. [PMID: 15792368] - R de la Torre, X de la Torre, C Alía, J Segura, T Baró, J M Torres-Rodríguez. Changes in androgenic steroid profile due to urine contamination by microorganisms: a prospective study in the context of doping control.
Analytical biochemistry.
2001 Feb; 289(2):116-23. doi:
10.1006/abio.2000.4918. [PMID: 11161304] - M L Barbaccia, S Lello, T Sidiropoulou, T Cocco, R P Sorge, A Cocchiarale, V Piermarini, A F Sabato, M Trabucchi, C Romanini. Plasma 5alpha-androstane-3alpha,17betadiol, an endogenous steroid that positively modulates GABA(A) receptor function, and anxiety: a study in menopausal women.
Psychoneuroendocrinology.
2000 Oct; 25(7):659-75. doi:
10.1016/s0306-4530(00)00017-2. [PMID: 10938447] - S K Agarwal, H L Judd, D A Magoffin. A mechanism for the suppression of estrogen production in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism.
1996 Oct; 81(10):3686-91. doi:
10.1210/jcem.81.10.8855823. [PMID: 8855823] - M Callender, H Benghuzzi, M Tucci, A Mohamed, Z Cason, L Lemos, A Tsao. Immunochemical and histopathological evaluation associated with sustained delivery of 5-alpha androstanedione using adult rats as a model.
Biomedical sciences instrumentation.
1996; 32(?):55-62. doi:
. [PMID: 8672690] - H Dai, F W Edens, R M Roe. Glutathione S-transferases in the Japanese quail: tissue distribution and purification of the liver isozymes.
Journal of biochemical toxicology.
1996; 11(2):85-96. doi:
10.1002/(sici)1522-7146(1996)11:2<85::aid-jbt6>3.0.co;2-q. [PMID: 8884469] - L Milewich, J D Madden, C E Gomez-Sanchez. 5 alpha-androstane-3,17-dione in peripheral plasma of men and women.
The Journal of steroid biochemistry and molecular biology.
1992 Feb; 41(2):185-90. doi:
10.1016/0960-0760(92)90047-m. [PMID: 1543687] - M Canonaco, S Andò, A Valenti, R Tavolaro, M L Panno, M Maggiolini, F Dessì-Fulgheri. The in-vitro transformation of [3H]dehydroepiandrosterone into its principal metabolites in the adrenal cortex of adult castrated male rats and following steroid treatment.
The Journal of endocrinology.
1989 Jun; 121(3):419-24. doi:
10.1677/joe.0.1210419. [PMID: 2526845] - B A Schlinger, G V Callard. Aromatase activity in quail brain: correlation with aggressiveness.
Endocrinology.
1989 Jan; 124(1):437-43. doi:
10.1210/endo-124-1-437. [PMID: 2909376] - E Perel, D Daniilescu, S Kindler, L Kharlip, D W Killinger. The formation of 5 alpha-reduced androgens in stromal cells from human breast adipose tissue.
The Journal of clinical endocrinology and metabolism.
1986 Feb; 62(2):314-8. doi:
10.1210/jcem-62-2-314. [PMID: 3941160] - L A Loseva, V G Degtiar', V A Isachenkov. [Changes in the concentration of luteinizing hormone in the blood serum and of luliberin in the hypothalamus of castrated rats after the administration of testosterone and its 5 alpha-reduced metabolites. I].
Problemy endokrinologii.
1980; 26(6):46-50. doi:
NULL. [PMID: 7005892]