(r)-Salmeterol (BioDeep_00000844300)

   


代谢物信息卡片


(r)-Salmeterol

化学式: C25H37NO4 (415.27224420000005)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
InChI: InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2/t25-/m0/s1

描述信息

同义名列表

1 个代谢物同义名

(r)-Salmeterol



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • D J Nicholls, S Jordan, E Cadogan, M Lawson, R P Austin, S W Paine, P Gardiner, R Bonnert, S Connolly, A Young. Characteristics of AZD9708, a novel, selective β2-adrenoceptor agonist with rapid onset and long duration of action. Pulmonary pharmacology & therapeutics. 2012 Aug; 25(4):293-302. doi: 10.1016/j.pupt.2012.05.008. [PMID: 22659538]
  • Nan-Chang Song, Jin-Bao He, Han-Bin Xu, Ji-Feng Wu. [Comparative study on effect of acupoint heat-sensitive moxibustion and Seretide on the symptoms of bronchial asthma at chronic persistent stage]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2012 Jul; 32(7):593-6. doi: ". [PMID: 22997785]
  • John B Hagan, Brian C Netzel, Marc R Matthews, Nichole L Korpi-Steiner, Ravinder J Singh. Urinary fluticasone propionate-17beta-carboxylic acid to assess asthma therapy adherence. Allergy and asthma proceedings. 2012 Jul; 33(4):e35-9. doi: 10.2500/aap.2012.33.3568. [PMID: 22856629]
  • Luigi Silvestro, Simona Rizea Savu, Simona Nicoleta Savu, Ariana Tudoroniu, Isabela Tarcomnicu. Development of a sensitive method for simultaneous determination of fluticasone propionate and salmeterol in plasma samples by liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC. 2012 May; 26(5):627-35. doi: 10.1002/bmc.1708. [PMID: 22577660]
  • José L López-Campos, Elena Arellano, Carmen Calero, Ana Delgado, Eduardo Márquez, Pilar Cejudo, Francisco Ortega, Francisco Rodríguez-Panadero, Ana Montes-Worboys. Determination of inflammatory biomarkers in patients with COPD: a comparison of different assays. BMC medical research methodology. 2012 Mar; 12(?):40. doi: 10.1186/1471-2288-12-40. [PMID: 22463705]
  • David A Lomas, David A Lipson, Bruce E Miller, Lisa Willits, Oliver Keene, Helen Barnacle, Neil C Barnes, Ruth Tal-Singer. An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease. Journal of clinical pharmacology. 2012 Mar; 52(3):416-24. doi: 10.1177/0091270010397050. [PMID: 22090363]
  • Yukako Ito, Masahiro Yoshimura, Tsutomu Tanaka, Kanji Takada. Effect of lipophilicity on the bioavailability of drugs after percutaneous administration by dissolving microneedles. Journal of pharmaceutical sciences. 2012 Mar; 101(3):1145-56. doi: 10.1002/jps.22814. [PMID: 22086760]
  • Rhys M Jones, Anthony Harrison. A new methodology for predicting human pharmacokinetics for inhaled drugs from oratracheal pharmacokinetic data in rats. Xenobiotica; the fate of foreign compounds in biological systems. 2012 Jan; 42(1):75-85. doi: 10.3109/00498254.2011.626465. [PMID: 22077102]
  • Catherine E Morris, Pierre-Alexandre Boucher, Béla Joós. Left-shifted nav channels in injured bilayer: primary targets for neuroprotective nav antagonists?. Frontiers in pharmacology. 2012; 3(?):19. doi: 10.3389/fphar.2012.00019. [PMID: 22375118]
  • Robert J Walker, Nancy M Anderson, Suleiman Bahouth, Jena J Steinle. Silencing of insulin receptor substrate-1 increases cell death in retinal Müller cells. Molecular vision. 2012; 18(?):271-9. doi: NULL. [PMID: 22328823]
  • Hiromasa Saitoh, Shizuko Fujisawa, Chikako Mitsuoka, Akiko Ito, Akiko Hirabuchi, Kyoko Ikeda, Hiroki Irieda, Kae Yoshino, Kentaro Yoshida, Hideo Matsumura, Yukio Tosa, Joe Win, Sophien Kamoun, Yoshitaka Takano, Ryohei Terauchi. Large-scale gene disruption in Magnaporthe oryzae identifies MC69, a secreted protein required for infection by monocot and dicot fungal pathogens. PLoS pathogens. 2012; 8(5):e1002711. doi: 10.1371/journal.ppat.1002711. [PMID: 22589729]
  • Robert J Walker, Nancy M Anderson, Youde Jiang, Suleiman Bahouth, Jena J Steinle. Role of β-adrenergic receptor regulation of TNF-α and insulin signaling in retinal Muller cells. Investigative ophthalmology & visual science. 2011 Dec; 52(13):9527-33. doi: 10.1167/iovs.11-8631. [PMID: 22110065]
  • Cong-Hong Yu, Dai-Liang Liang, Jiang-Ning Guo, Quan-Xi Mei, De-Po Yang. [Study on the chemical constituents from the aerial parts of Medicago sativa and their hypolipidemic activity]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Nov; 34(11):1709-11. doi: . [PMID: 22506393]
  • Peter Reilich, Rita Horvath, Sabine Krause, Nicolai Schramm, Doug M Turnbull, Michael Trenell, Kieren G Hollingsworth, Grainne S Gorman, Volkmar H Hans, Jens Reimann, Andrée MacMillan, Lesley Turner, Annette Schollen, Gregor Witte, Birgit Czermin, Elke Holinski-Feder, Maggie C Walter, Benedikt Schoser, Hanns Lochmüller. The phenotypic spectrum of neutral lipid storage myopathy due to mutations in the PNPLA2 gene. Journal of neurology. 2011 Nov; 258(11):1987-97. doi: 10.1007/s00415-011-6055-4. [PMID: 21544567]
  • Sonia Radice, Anna Milanesi, Stefania Antoniazzi, Valentina Perrone, Carla Carnovale, Emilio Clementi. A case of haemorrhagic cystitis by inhaled salbutamol and salmeterol. European journal of clinical pharmacology. 2011 Nov; 67(11):1203-4. doi: 10.1007/s00228-011-1068-6. [PMID: 21638032]
  • Lester I Harrison, Christopher C Novak, Michael J Needham, Paul Ratner. Comparative pulmonary function and pharmacokinetics of fluticasone propionate and salmeterol xinafoate delivered by two dry powder inhalers to patients with asthma. Journal of aerosol medicine and pulmonary drug delivery. 2011 Oct; 24(5):245-52. doi: 10.1089/jamp.2011.0884. [PMID: 21671752]
  • Koen Deventer, Oscar J Pozo, Frans T Delbeke, Peter Van Eenoo. Quantitative detection of inhaled salmeterol in human urine and relevance to doping control analysis. Therapeutic drug monitoring. 2011 Oct; 33(5):627-31. doi: 10.1097/ftd.0b013e318229c5f4. [PMID: 21912333]
  • Ana Catarina Matos, Umasuthan Srirangalingam, Tracy Barry, Ashley B Grossman. Cushing's syndrome with low levels of serum cortisol: the role of inhaled steroids. Clinical medicine (London, England). 2011 Aug; 11(4):404-5. doi: 10.7861/clinmedicine.11-4-404. [PMID: 21853845]
  • Charlie C Xue, Johannah L Shergis, Anthony L Zhang, Christopher Worsnop, Harry Fong, David Story, Cliff Da Costa, Francis Ck Thien. Panax ginseng C.A Meyer root extract for moderate chronic obstructive pulmonary disease (COPD): study protocol for a randomised controlled trial. Trials. 2011 Jun; 12(?):164. doi: 10.1186/1745-6215-12-164. [PMID: 21718484]
  • Christina Orsmark Pietras, Johanna Vendelin, Francesca Anedda, Sara Bruce, Mikael Adner, Lilli Sundman, Ville Pulkkinen, Harri Alenius, Mauro D'Amato, Cilla Söderhäll, Juha Kere. The asthma candidate gene NPSR1 mediates isoform specific downstream signalling. BMC pulmonary medicine. 2011 Jun; 11(?):39. doi: 10.1186/1471-2466-11-39. [PMID: 21707994]
  • P R Cooper, R C Kurten, J Zhang, D J Nicholls, I A Dainty, R A Panettieri. Formoterol and salmeterol induce a similar degree of β2-adrenoceptor tolerance in human small airways but via different mechanisms. British journal of pharmacology. 2011 Jun; 163(3):521-32. doi: 10.1111/j.1476-5381.2011.01257.x. [PMID: 21306583]
  • Christian de Mey, Nassr Nassr, Gezim Lahu. No relevant cardiac, pharmacokinetic or safety interactions between roflumilast and inhaled formoterol in healthy subjects: an open-label, randomised, actively controlled study. BMC clinical pharmacology. 2011 Jun; 11(?):7. doi: 10.1186/1472-6904-11-7. [PMID: 21631929]
  • Paola Casarosa, Ines Kollak, Tobias Kiechle, Angela Ostermann, Andreas Schnapp, Ralf Kiesling, Michael Pieper, Peter Sieger, Florian Gantner. Functional and biochemical rationales for the 24-hour-long duration of action of olodaterol. The Journal of pharmacology and experimental therapeutics. 2011 Jun; 337(3):600-9. doi: 10.1124/jpet.111.179259. [PMID: 21357659]
  • Helen Ilumets, Witold Mazur, Tuula Toljamo, Noora Louhelainen, Pentti Nieminen, Hideo Kobayashi, Nobuhisa Ishikawa, Vuokko L Kinnula. Ageing and smoking contribute to plasma surfactant proteins and protease imbalance with correlations to airway obstruction. BMC pulmonary medicine. 2011 Apr; 11(?):19. doi: 10.1186/1471-2466-11-19. [PMID: 21504569]
  • Arun Nair, Lorna McKinlay, Peter Williamson, Philip Short, Patricia Burns, Brian J Lipworth. Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers. European journal of clinical pharmacology. 2011 04; 67(4):355-363. doi: 10.1007/s00228-010-0989-9. [PMID: 21240480]
  • Raissa Rr Aworet-Samseny, Alain Souza, Fidele Kpahé, Kiessoun Konaté, Jacques Y Datté. Dichrostachys cinerea (L.) Wight et Arn (Mimosaceae) hydro-alcoholic extract action on the contractility of tracheal smooth muscle isolated from guinea-pig. BMC complementary and alternative medicine. 2011 Mar; 11(?):23. doi: 10.1186/1472-6882-11-23. [PMID: 21414220]
  • Peter M A Calverley, Robert A Stockley, Terence A R Seemungal, Gerry Hagan, Lisa R Willits, John H Riley, Jadwiga A Wedzicha. Reported pneumonia in patients with COPD: findings from the INSPIRE study. Chest. 2011 Mar; 139(3):505-512. doi: 10.1378/chest.09-2992. [PMID: 20576732]
  • Keiichiro Akamatsu, Kazuto Matsunaga, Hisatoshi Sugiura, Akira Koarai, Tsunahiko Hirano, Yoshiaki Minakata, Masakazu Ichinose. Improvement of Airflow Limitation by Fluticasone Propionate/Salmeterol in Chronic Obstructive Pulmonary Disease: What is the Specific Marker?. Frontiers in pharmacology. 2011; 2(?):36. doi: 10.3389/fphar.2011.00036. [PMID: 21811461]
  • Chun-hua Wei, Ming-chun Wen, Nong Yu. [Clinical effect of chaipo granule combined with routine treatment on refractory asthma]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 2011 Jan; 31(1):33-6. doi: . [PMID: 21434340]
  • P Garcia, A-C Paris, J Gil, M-A Popot, Y Bonnaire. Analysis of β-agonists by HPLC/ESI-MS(n) in horse doping control. Biomedical chromatography : BMC. 2011 Jan; 25(1-2):147-54. doi: 10.1002/bmc.1562. [PMID: 21204111]
  • Andreina Bruno, Marinella Alessi, Simona Soresi, Anna Bonanno, Loredana Riccobono, Angela Marina Montalbano, Giusy Daniela Albano, Mark Gjomarkaj, Mirella Profita. Increased leptin/leptin receptor pathway affects systemic and airway inflammation in COPD former smokers. Journal of inflammation research. 2011; 4(?):51-9. doi: 10.2147/jir.s19523. [PMID: 22096369]
  • James F Donohue, Dave Singh, Oliver Kornmann, David Lawrence, Cheryl Lassen, Benjamin Kramer. Safety of indacaterol in the treatment of patients with COPD. International journal of chronic obstructive pulmonary disease. 2011; 6(?):477-92. doi: 10.2147/copd.s23816. [PMID: 22003293]
  • Jean-Philippe Fortin, Daniel Chinnapen, Martin Beinborn, Wayne Lencer, Alan S Kopin. Discovery of dual-action membrane-anchored modulators of incretin receptors. PloS one. 2011; 6(9):e24693. doi: 10.1371/journal.pone.0024693. [PMID: 21935440]
  • Jorge F Maspero, Hendrik Nolte, Iván Chérrez-Ojeda. Long-term safety of mometasone furoate/formoterol combination for treatment of patients with persistent asthma. The Journal of asthma : official journal of the Association for the Care of Asthma. 2010 Dec; 47(10):1106-15. doi: 10.3109/02770903.2010.514634. [PMID: 20874458]
  • Yasuteru Sugino, Ryo Sanda, Yasuyuki Takagi, Motoaki Kato, Akiko Ohta, Junya Okumura, Hideaki Nagai. [A case of severe asthma responsive to omalizumab treatment despite a low serum IgE level and lack of sensitized allergens]. Arerugi = [Allergy]. 2010 Nov; 59(11):1572-9. doi: . [PMID: 21119303]
  • Stéphanie Proulx, Jeanne d'Arc Uwamaliya, Patrick Carrier, Alexandre Deschambeault, Caroline Audet, Claude J Giasson, Sylvain L Guérin, François A Auger, Lucie Germain. Reconstruction of a human cornea by the self-assembly approach of tissue engineering using the three native cell types. Molecular vision. 2010 Oct; 16(?):2192-201. doi: NULL. [PMID: 21139684]
  • Davood Attaran, Shahrzad M Lari, Mohammad Towhidi, Hassan Ghobadi Marallu, Hossein Ayatollahi, Mohammad Khajehdaluee, Mostafa Ghanei, Reza Basiri. Interleukin-6 and airflow limitation in chemical warfare patients with chronic obstructive pulmonary disease. International journal of chronic obstructive pulmonary disease. 2010 Oct; 5(?):335-40. doi: 10.2147/copd.s12545. [PMID: 21037957]
  • Jian Xu, Rüdiger Nave, Gezim Lahu, Eric Derom, Hartmut Derendorf. Population pharmacokinetics and pharmacodynamics of inhaled ciclesonide and fluticasone propionate in patients with persistent asthma. Journal of clinical pharmacology. 2010 Oct; 50(10):1118-27. doi: 10.1177/0091270009354994. [PMID: 20150524]
  • Elizabeth M Rosethorne, Robert J Turner, Robin A Fairhurst, Steven J Charlton. Efficacy is a contributing factor to the clinical onset of bronchodilation of inhaled beta(2)-adrenoceptor agonists. Naunyn-Schmiedeberg's archives of pharmacology. 2010 Sep; 382(3):255-63. doi: 10.1007/s00210-010-0533-6. [PMID: 20694793]
  • Frank Bedon, Claude Bomal, Sébastien Caron, Caroline Levasseur, Brian Boyle, Shawn D Mansfield, Axel Schmidt, Jonathan Gershenzon, Jacqueline Grima-Pettenati, Armand Séguin, John MacKay. Subgroup 4 R2R3-MYBs in conifer trees: gene family expansion and contribution to the isoprenoid- and flavonoid-oriented responses. Journal of experimental botany. 2010 Sep; 61(14):3847-64. doi: 10.1093/jxb/erq196. [PMID: 20732878]
  • Jen-Tzer Gau, Utkarsh Acharya, Salman Khan, Victor Heh, Lona Mody, Tzu-Cheg Kao. Pharmacotherapy and the risk for community-acquired pneumonia. BMC geriatrics. 2010 Jul; 10(?):45. doi: 10.1186/1471-2318-10-45. [PMID: 20604960]
  • Karine L Clearie, Peter A Williamson, Sriram Vaidyanathan, Jeannine Du Bois, Haylene Nell, Brian J Lipworth. Systemic bioavailability of hydrofluoroalkane (HFA) formulations of fluticasone/salmeterol in healthy volunteers via pMDI alone and spacer. British journal of clinical pharmacology. 2010 Jun; 69(6):637-44. doi: 10.1111/j.1365-2125.2010.03655.x. [PMID: 20565455]
  • Francisco Garcia-Rio, Marc Miravitlles, Joan B Soriano, Luis Muñoz, Enric Duran-Tauleria, Guadalupe Sánchez, Víctor Sobradillo, Julio Ancochea. Systemic inflammation in chronic obstructive pulmonary disease: a population-based study. Respiratory research. 2010 May; 11(?):63. doi: 10.1186/1465-9921-11-63. [PMID: 20500811]
  • Daniele Di Corcia, Veronica Morra, Marco Pazzi, Marco Vincenti. Simultaneous determination of beta2-agonists in human urine by fast-gas chromatography/mass spectrometry: method validation and clinical application. Biomedical chromatography : BMC. 2010 Apr; 24(4):358-66. doi: 10.1002/bmc.1300. [PMID: 19642085]
  • R J B Peters, J E Oosterink, A A M Stolker, C Georgakopoulos, M W F Nielen. Generic sample preparation combined with high-resolution liquid chromatography-time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories. Analytical and bioanalytical chemistry. 2010 Apr; 396(7):2583-98. doi: 10.1007/s00216-010-3484-3. [PMID: 20155493]
  • Gregory Feldman, Thomas Siler, Niyati Prasad, Damon Jack, Simon Piggott, Roger Owen, Mark Higgins, Benjamin Kramer. Efficacy and safety of indacaterol 150 microg once-daily in COPD: a double-blind, randomised, 12-week study. BMC pulmonary medicine. 2010 Mar; 10(?):11. doi: 10.1186/1471-2466-10-11. [PMID: 20211002]
  • Ericka R Havecker, Laura M Wallbridge, Thomas J Hardcastle, Maxwell S Bush, Krystyna A Kelly, Ruth M Dunn, Frank Schwach, John H Doonan, David C Baulcombe. The Arabidopsis RNA-directed DNA methylation argonautes functionally diverge based on their expression and interaction with target loci. The Plant cell. 2010 Feb; 22(2):321-34. doi: 10.1105/tpc.109.072199. [PMID: 20173091]
  • Sharat J Vayttaden, Jacqueline Friedman, Tuan M Tran, Thomas C Rich, Carmen W Dessauer, Richard B Clark. Quantitative modeling of GRK-mediated beta2AR regulation. PLoS computational biology. 2010 Jan; 6(1):e1000647. doi: 10.1371/journal.pcbi.1000647. [PMID: 20098494]
  • Allison F Williams, Elizabeth Manias, Rowan G Walker. The devil is in the detail - a multifactorial intervention to reduce blood pressure in co-existing diabetes and chronic kidney disease: a single blind, randomized controlled trial. BMC family practice. 2010 Jan; 11(?):3. doi: 10.1186/1471-2296-11-3. [PMID: 20064272]
  • Ganesh N Sharma, Man Mohan Singhal, K K Sharma, Jyotsana Sanadya. Trouble shooting during bioanalytical estimation of drug and metabolites using lc-ms/ms: a review. Journal of advanced pharmaceutical technology & research. 2010 Jan; 1(1):1-10. doi: NULL. [PMID: 22247825]
  • Dario Lombardi, Bernard Cuenoud, Stefanie D Krämer. Lipid membrane interactions of indacaterol and salmeterol: do they influence their pharmacological properties?. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2009 Dec; 38(5):533-47. doi: 10.1016/j.ejps.2009.10.001. [PMID: 19819331]
  • Jeanine M D'Armiento, Steven M Scharf, Michael D Roth, John E Connett, Andrew Ghio, David Sternberg, Jonathan G Goldin, Thomas A Louis, Jenny T Mao, George T O'Connor, Joe W Ramsdell, Andrew L Ries, Neil W Schluger, Frank C Sciurba, Melissa A Skeans, Helen Voelker, Robert E Walter, Christine H Wendt, Gail G Weinmann, Robert A Wise, Robert F Foronjy. Eosinophil and T cell markers predict functional decline in COPD patients. Respiratory research. 2009 Nov; 10(?):113. doi: 10.1186/1465-9921-10-113. [PMID: 19925666]
  • Chris Dalby, Tomasz Polanowski, Thomas Larsson, Lars Borgström, Staffan Edsbäcker, Tim W Harrison. The bioavailability and airway clearance of the steroid component of budesonide/formoterol and salmeterol/fluticasone after inhaled administration in patients with COPD and healthy subjects: a randomized controlled trial. Respiratory research. 2009 Oct; 10(?):104. doi: 10.1186/1465-9921-10-104. [PMID: 19878590]
  • Thérèse S Lapperre, Jiska B Snoeck-Stroband, Margot M E Gosman, Désirée F Jansen, Annemarie van Schadewijk, Henk A Thiadens, Judith M Vonk, H Marike Boezen, Nick H T Ten Hacken, Jacob K Sont, Klaus F Rabe, Huib A M Kerstjens, Pieter S Hiemstra, Wim Timens, Dirkje S Postma, Peter J Sterk. Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial. Annals of internal medicine. 2009 Oct; 151(8):517-27. doi: 10.7326/0003-4819-151-8-200910200-00004. [PMID: 19841453]
  • Talal M Nsouli. Inhaled mometasone furoate for the management of refractory oral corticosteroid-dependent asthma: a case report. Cases journal. 2009 Sep; 2(?):7770. doi: 10.1186/1757-1626-0002-0000007770. [PMID: 20181197]
  • M Lommatzsch, Y Lindner, A Edner, K Bratke, M Kuepper, J C Virchow. Adverse effects of salmeterol in asthma: a neuronal perspective. Thorax. 2009 Sep; 64(9):763-9. doi: 10.1136/thx.2008.110916. [PMID: 19237390]
  • Makoto Hoshino, Hiroshi Handa, Teruomi Miyazawa. Effects of salmeterol and fluticasone propionate combination versus fluticasone propionate on airway function and eosinophilic inflammation in mild asthma. Allergology international : official journal of the Japanese Society of Allergology. 2009 Sep; 58(3):357-63. doi: 10.2332/allergolint.08-oa-0065. [PMID: 19454840]
  • Arun Nair, Karine Clearie, Daniel Menzies, Karen Meldrum, Lesley McFarlane, Brian J Lipworth. A novel breath-actuated integrated vortex spacer device increases relative lung bioavailability of fluticasone/salmeterol in combination. Pulmonary pharmacology & therapeutics. 2009 Aug; 22(4):305-10. doi: 10.1016/j.pupt.2009.02.001. [PMID: 19489129]
  • Massimiliano Sorbello, Alessandro Laudini, Gianluigi Morello, Mirco Tindaro Sidoti, Jessica Giuseppina Maugeri, Alessia Giaquinta, Tiziano Tallarita, Daniela Corona, Domenico Zerbo, Alessandro Cappellani, Pierfrancesco Veroux, Laura Parrinello, Massimiliano Veroux. Anaesthesiological implications of Kimura's disease: a case report. Journal of medical case reports. 2009 Jun; 3(?):7316. doi: 10.4076/1752-1947-3-7316. [PMID: 19830181]
  • E Derom, R Louis, C Tiesler, R Engelstätter, J-M Kaufman, G F Joos. Effects of ciclesonide and fluticasone on cortisol secretion in patients with persistent asthma. The European respiratory journal. 2009 Jun; 33(6):1277-86. doi: 10.1183/09031936.00079908. [PMID: 19164356]
  • M Degen, S Goulet, J Ferralli, M Roth, M Tamm, R Chiquet-Ehrismann. Opposite effect of fluticasone and salmeterol on fibronectin and tenascin-C expression in primary human lung fibroblasts. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2009 May; 39(5):688-99. doi: 10.1111/j.1365-2222.2009.03220.x. [PMID: 19309351]
  • B Seruga, H K Gan, J J Knox. Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer. Current oncology (Toronto, Ont.). 2009 May; 16 Suppl 1(?):S52-9. doi: 10.3747/co.v16i0.402. [PMID: 19478903]
  • Terence L Fodey, Nuala M Greer, Steven R H Crooks. Antibody production: Low dose immunogen vs. low incorporation hapten using salmeterol as a model. Analytica chimica acta. 2009 Apr; 637(1-2):328-32. doi: 10.1016/j.aca.2008.09.025. [PMID: 19286047]
  • Dario Lombardi, Bernard Cuenoud, Heidi Wunderli-Allenspach, Stefanie D Krämer. Interaction kinetics of salmeterol with egg phosphatidylcholine liposomes by surface plasmon resonance. Analytical biochemistry. 2009 Feb; 385(2):215-23. doi: 10.1016/j.ab.2008.11.011. [PMID: 19084493]
  • Peter T Daley-Yates, David A Parkins, Marian J Thomas, Benjamin Gillett, Karen W House, Hector G Ortega. Pharmacokinetic, pharmacodynamic, efficacy, and safety data from two randomized, double-blind studies in patients with asthma and an in vitro study comparing two dry-powder inhalers delivering a combination of salmeterol 50 microg and fluticasone propionate 250 microg: implications for establishing bioequivalence of inhaled products. Clinical therapeutics. 2009 Feb; 31(2):370-85. doi: 10.1016/j.clinthera.2009.02.007. [PMID: 19302910]
  • Lars Lüthje, Tobias Raupach, Hellmuth Michels, Bernhard Unsöld, Gerd Hasenfuss, Harald Kögler, Stefan Andreas. Exercise intolerance and systemic manifestations of pulmonary emphysema in a mouse model. Respiratory research. 2009 Jan; 10(?):7. doi: 10.1186/1465-9921-10-7. [PMID: 19175913]
  • Umme Kolsum, Kay Roy, Cerys Starkey, Zoë Borrill, Nick Truman, Jørgen Vestbo, Dave Singh. The repeatability of interleukin-6, tumor necrosis factor-alpha, and C-reactive protein in COPD patients over one year. International journal of chronic obstructive pulmonary disease. 2009; 4(?):149-56. doi: 10.2147/copd.s5018. [PMID: 19436686]
  • Raphael Briot, Sam Bayat, Daniel Anglade, Jean-Louis Martiel, Francis Grimbert. Increased cardiac index due to terbutaline treatment aggravates capillary-alveolar macromolecular leakage in oleic acid lung injury in dogs. Critical care (London, England). 2009; 13(5):R166. doi: 10.1186/cc8137. [PMID: 19845949]
  • Thomas P Vacek, Utpal Sen, Neetu Tyagi, Jonathan C Vacek, Munish Kumar, William M Hughes, John C Passmore, Suresh C Tyagi. Differential expression of Gs in a murine model of homocysteinemic heart failure. Vascular health and risk management. 2009; 5(1):79-84. doi: 10.2147/vhrm.s4121. [PMID: 19436674]
  • Etienne de Montmollin, Jerome Aboab, Arnaud Mansart, Djillali Annane. Bench-to-bedside review: Beta-adrenergic modulation in sepsis. Critical care (London, England). 2009; 13(5):230. doi: 10.1186/cc8026. [PMID: 19863760]
  • Spencer J Carter, Vladimír Cápka. Investigation of interaction between salmeterol and fluticasone propionate and its effect on quantitative accuracy of an LC/MS/MS assay in human plasma at low pg/mL concentrations. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2008 Dec; 876(2):163-9. doi: 10.1016/j.jchromb.2008.10.034. [PMID: 19010742]
  • Martin C Michel, Sergio Parra. Similarities and differences in the autonomic control of airway and urinary bladder smooth muscle. Naunyn-Schmiedeberg's archives of pharmacology. 2008 Aug; 378(2):217-24. doi: 10.1007/s00210-008-0316-5. [PMID: 18548230]
  • Hans Jürgen Hoffmann, Lars Peter Nielsen, Henrik Harving, John H Heinig, Ronald Dahl. Asthmatics able to step down from inhaled corticosteroid treatment without loss of asthma control have low serum eotaxin/CCL11. The clinical respiratory journal. 2008 Jul; 2(3):149-57. doi: 10.1111/j.1752-699x.2008.00054.x. [PMID: 20298323]
  • Gábor Dancs, Mihály Kondrák, Zsófia Bánfalvi. The effects of enhanced methionine synthesis on amino acid and anthocyanin content of potato tubers. BMC plant biology. 2008 Jun; 8(?):65. doi: 10.1186/1471-2229-8-65. [PMID: 18549488]
  • Don D Sin, S F Paul Man, Darcy D Marciniuk, Gordon Ford, Mark FitzGerald, Eric Wong, Ernest York, Rajesh R Mainra, Warren Ramesh, Lyle S Melenka, Eric Wilde, Robert L Cowie, Dave Williams, Wen Q Gan, Roxanne Rousseau. The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine. 2008 Jun; 177(11):1207-14. doi: 10.1164/rccm.200709-1356oc. [PMID: 18310480]
  • M Rabbani, S E Sajjadi, A Mohammadi. Evaluation of the anxiolytic effect of Nepeta persica Boiss. in mice. Evidence-based complementary and alternative medicine : eCAM. 2008 Jun; 5(2):181-6. doi: 10.1093/ecam/nem017. [PMID: 18604252]
  • Ken M Kunisaki, Kathryn L Rice, Edward N Janoff, Thomas S Rector, Dennis E Niewoehner. Exhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: a prospective study. Therapeutic advances in respiratory disease. 2008 Apr; 2(2):55-64. doi: 10.1177/1753465808088902. [PMID: 19124359]
  • A Jan Hendriks, Christian Mulder. Scaling of offspring number and mass to plant and animal size: model and meta-analysis. Oecologia. 2008 Apr; 155(4):705-16. doi: 10.1007/s00442-007-0952-3. [PMID: 18196279]
  • M E Stegenga, S N van der Crabben, M C Dessing, J M Pater, P S van den Pangaart, A F de Vos, M W Tanck, D Roos, H P Sauerwein, T van der Poll. Effect of acute hyperglycaemia and/or hyperinsulinaemia on proinflammatory gene expression, cytokine production and neutrophil function in humans. Diabetic medicine : a journal of the British Diabetic Association. 2008 Feb; 25(2):157-64. doi: 10.1111/j.1464-5491.2007.02348.x. [PMID: 18290856]
  • Jaume Sauleda, Aina Noguera, David Blanquer, Jaume Pons, Meritxell López, Cristina Villena, Alvar G N Agustí. Pulmonary and systemic hepatocyte and keratinocyte growth factors in patients with chronic obstructive pulmonary disease. International journal of chronic obstructive pulmonary disease. 2008; 3(4):719-25. doi: 10.2147/copd.s3078. [PMID: 19281086]
  • T Yamagata, T Hirano, H Sugiura, S Yanagisawa, T Ichikawa, K Ueshima, K Akamatsu, M Nakanishi, K Matsunaga, Y Minakata, M Ichinose. Comparison of bronchodilatory properties of transdermal and inhaled long-acting beta 2-agonists. Pulmonary pharmacology & therapeutics. 2008; 21(1):160-5. doi: 10.1016/j.pupt.2007.05.004. [PMID: 17632023]
  • Yeonyee Oh, Nicole Donofrio, Huaqin Pan, Sean Coughlan, Douglas E Brown, Shaowu Meng, Thomas Mitchell, Ralph A Dean. Transcriptome analysis reveals new insight into appressorium formation and function in the rice blast fungus Magnaporthe oryzae. Genome biology. 2008; 9(5):R85. doi: 10.1186/gb-2008-9-5-r85. [PMID: 18492280]
  • Vladimír Cápka, Spencer J Carter. Minimizing matrix effects in the development of a method for the determination of salmeterol in human plasma by LC/MS/MS at low pg/mL concentration levels. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Sep; 856(1-2):285-93. doi: 10.1016/j.jchromb.2007.06.010. [PMID: 17625989]
  • Kenneth Kim, Javier Quesada, Nancy Szmaydy-Rikken, Patrick Darken, Tushar Shah. Intranasal ciclesonide coadministration with inhaled fluticasone propionate-salmeterol does not suppress cortisol in allergic rhinitis patients. The Journal of asthma : official journal of the Association for the Care of Asthma. 2007 Sep; 44(7):515-20. doi: 10.1080/02770900701496007. [PMID: 17885853]
  • Robert L Cowie, Louis-Philippe Boulet, Paul K Keith, Catherine A Scott-Wilson, Karen W House, Paul M Dorinsky. Tolerability of a salmeterol xinafoate/fluticasone propionate hydrofluoroalkane metered-dose inhaler in adolescent and adult patients with persistent asthma: a 52-week, open-label, stratified, parallel-group, multicenter study. Clinical therapeutics. 2007 Jul; 29(7):1390-402. doi: 10.1016/j.clinthera.2007.07.021. [PMID: 17825690]
  • Mohammed A Alzoghaibi, Ahmed S Bahammam. Lipid peroxides in stable asthmatics receiving inhaled steroids and long-acting beta2 -agonists. Respirology (Carlton, Vic.). 2007 May; 12(3):439-42. doi: 10.1111/j.1440-1843.2007.01034.x. [PMID: 17539852]
  • Yu Te Chu, Wen Chiang, Tsu Nai Wang, Chih Hsing Hung, Yuh Jyh Jong, Jiunn Ren Wu. Changes in serum eotaxin and eosinophil cationic protein levels, and eosinophil count during treatment of childhood asthma. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi. 2007 Apr; 40(2):162-7. doi: . [PMID: 17446966]
  • Denis Caillaud, Charles Le Merre, Yan Martinat, Bernard Aguilaniu, Demetri Pavia. A dose-ranging study of tiotropium delivered via Respimat Soft Mist Inhaler or HandiHaler in COPD patients. International journal of chronic obstructive pulmonary disease. 2007; 2(4):559-65. doi: NULL. [PMID: 18268929]
  • Simin Khaliq, Franz-Josef Volk, August Wilhelm Frahm. Phytochemical investigation of Perovskia abrotanoides. Planta medica. 2007 Jan; 73(1):77-83. doi: 10.1055/s-2006-951766. [PMID: 17315312]
  • Cristina Legido-Quigley, Norman W Smith. Short polystyrene monolith-fritted micro-liquid chromatography columns for rapid isocratic analysis of pharmaceuticals direct from plasma. Analytical and bioanalytical chemistry. 2006 Jun; 385(4):686-91. doi: 10.1007/s00216-006-0457-7. [PMID: 16741767]
  • Gary M Onady, Catherine L Farinet. An adult cystic fibrosis patient presenting with persistent dyspnea: case report. BMC pulmonary medicine. 2006 May; 6(?):9. doi: 10.1186/1471-2466-6-9. [PMID: 16681861]
  • J G Koopmans, R Lutter, H M Jansen, J S van der Zee. Adding salmeterol to an inhaled corticosteroid: long term effects on bronchial inflammation in asthma. Thorax. 2006 Apr; 61(4):306-12. doi: 10.1136/thx.2005.051292. [PMID: 16449264]
  • Julia G Koopmans, René Lutter, Henk M Jansen, Jaring S van der Zee. Adding salmeterol to an inhaled corticosteroid reduces allergen-induced serum IL-5 and peripheral blood eosinophils. The Journal of allergy and clinical immunology. 2005 Nov; 116(5):1007-13. doi: 10.1016/j.jaci.2005.08.016. [PMID: 16275368]
  • Tom C Fardon, Daniel K C Lee, Melissa R Hodge, Brian J Lipworth. Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2005 Sep; 95(3):259-65. doi: 10.1016/s1081-1206(10)61223-9. [PMID: 16200817]
  • Randolph Malone, Craig LaForce, Sai Nimmagadda, Lynne Schoaf, Karen House, Anna Ellsworth, Paul Dorinsky. The safety of twice-daily treatment with fluticasone propionate and salmeterol in pediatric patients with persistent asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2005 Jul; 95(1):66-71. doi: 10.1016/s1081-1206(10)61190-8. [PMID: 16095144]
  • Jacqueline L Olin. Tiotropium: an inhaled anticholinergic for chronic obstructive pulmonary disease. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2005 Jun; 62(12):1263-9. doi: 10.1093/ajhp/62.12.1263. [PMID: 15947126]
  • Rodger Kempsford, Malcolm Handel, Rashmi Mehta, Mariza De Silva, Peter Daley-Yates. Comparison of the systemic pharmacodynamic effects and pharmacokinetics of salmeterol delivered by CFC propellant and non-CFC propellant metered dose inhalers in healthy subjects. Respiratory medicine. 2005 Apr; 99 Suppl A(?):S11-9. doi: 10.1016/j.rmed.2004.11.005. [PMID: 15777604]
  • Donald W Cockcroft. Asthma and therapeutics: recombinant therapies in asthma. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology. 2005 Mar; 1(1):34-41. doi: 10.1186/1710-1492-1-1-34. [PMID: 20529233]
  • Daniel K C Lee, Thomas C Fardon, Caroline E Bates, Kay Haggart, Lesley C McFarlane, Brian J Lipworth. Airway and systemic effects of hydrofluoroalkane formulations of high-dose ciclesonide and fluticasone in moderate persistent asthma. Chest. 2005 Mar; 127(3):851-60. doi: 10.1378/chest.127.3.851. [PMID: 15764767]