(2E)-N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide (BioDeep_00000844265)
代谢物信息卡片
化学式: C27H22BrNO4S (535.0452832000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=C(C=C(C=C1)Br)S(=O)(=O)NC(=O)C=CC2=CC=CC=C2CC3=CC4=CC=CC=C4C=C3
InChI: InChI=1S/C27H22BrNO4S/c1-33-25-14-13-24(28)18-26(25)34(31,32)29-27(30)15-12-21-7-3-5-9-23(21)17-19-10-11-20-6-2-4-8-22(20)16-19/h2-16,18H,17H2,1H3,(H,29,30)/b15-12+
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fang-Fang Wang, Juan Ba, Xiao-Jing Yu, Xiao-Lian Shi, Jin-Jun Liu, Kai-Li Liu, Li-Yan Fu, Qing Su, Hong-Bao Li, Kai B Kang, Qiu-Yue Yi, Shu-Qiu Wang, Hong-Li Gao, Jie Qi, Ying Li, Guo-Qing Zhu, Yu-Ming Kang. Central Blockade of E-Prostanoid 3 Receptor Ameliorated Hypertension Partially by Attenuating Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus of Spontaneously Hypertensive Rats.
Cardiovascular toxicology.
2021 04; 21(4):286-300. doi:
10.1007/s12012-020-09619-w. [PMID: 33165770] - Chenggang Li, Xiaolei Liu, Yang Liu, Erik Zhang, Kantha Medepalli, Kouhei Masuda, Na Li, Kathryn A Wikenheiser-Brokamp, Andrew Osterburg, Michael T Borchers, Elizabeth J Kopras, David R Plas, Julia Sun, David N Franz, Jamie K Capal, Maxwell Mays, Yang Sun, David J Kwiatkowski, Anya Alayev, Marina K Holz, Darcy A Krueger, Brian J Siroky, Jane J Yu. Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells.
Molecular cancer research : MCR.
2017 10; 15(10):1318-1330. doi:
10.1158/1541-7786.mcr-17-0077. [PMID: 28710231] - Tingting Fang, Jiayun Hou, Mingyan He, Lingyan Wang, Minghuan Zheng, Xiangdong Wang, Jinglin Xia. Actinidia chinensis Planch root extract (acRoots) inhibits hepatocellular carcinoma progression by inhibiting EP3 expression.
Cell biology and toxicology.
2016 12; 32(6):499-511. doi:
10.1007/s10565-016-9351-z. [PMID: 27475644] - M J Jugus, J P Jaworski, P B Patra, J Jin, D M Morrow, N J Laping, R M Edwards, K S Thorneloe. Dual modulation of urinary bladder activity and urine flow by prostanoid EP3 receptors in the conscious rat.
British journal of pharmacology.
2009 Sep; 158(1):372-81. doi:
10.1111/j.1476-5381.2009.00275.x. [PMID: 19486006] - Xin Su, Lisa A Leon, Charlene W Wu, Dwight M Morrow, Jon-Paul Jaworski, J Paul Hieble, Erin S R Lashinger, Jian Jin, Richard M Edwards, Nicholas J Laping. Modulation of bladder function by prostaglandin EP3 receptors in the central nervous system.
American journal of physiology. Renal physiology.
2008 Oct; 295(4):F984-94. doi:
10.1152/ajprenal.90373.2008. [PMID: 18632791] - H Juteau, Y Gareau, M Labelle, C F Sturino, N Sawyer, N Tremblay, S Lamontagne, M C Carrière, D Denis, K M Metters. Structure-activity relationship of cinnamic acylsulfonamide analogues on the human EP3 prostanoid receptor.
Bioorganic & medicinal chemistry.
2001 Aug; 9(8):1977-84. doi:
10.1016/s0968-0896(01)00110-9. [PMID: 11504634]