4-[(4Z)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid (BioDeep_00000844137)
代谢物信息卡片
化学式: C24H19N3O6 (445.1274)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=C(C=C1C)[N+](=O)[O-])C2=CC=C(O2)C=C3C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C
InChI: InChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12-
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Jia Gu, Yan Lu, Menqing Deng, Ming Qiu, Yunfan Tian, Yue Ji, Pengyu Zong, Yongfeng Shao, Rui Zheng, Bin Zhou, Wei Sun, Xiangqing Kong. Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification.
Experimental & molecular medicine.
2019 07; 51(7):1-14. doi:
10.1038/s12276-019-0272-9. [PMID: 31292436] - B-H Bin, S-H Lee, J Bhin, T Irié, S Kim, J Seo, K Mishima, T R Lee, D Hwang, T Fukada, E-G Cho. The epithelial zinc transporter ZIP10 epigenetically regulates human epidermal homeostasis by modulating histone acetyltransferase activity.
The British journal of dermatology.
2019 04; 180(4):869-880. doi:
10.1111/bjd.17339. [PMID: 30339739] - Guofeng Chen, Anqi Liu, Yihan Xu, Li Gao, Mengmeng Jiang, Yan Li, Na Lv, Lei Zhou, Lili Wang, Li Yu, Yonghui Li. The RUNX1-ETO fusion protein trans-activates c-KIT expression by recruiting histone acetyltransferase P300 on its promoter.
The FEBS journal.
2019 03; 286(5):901-912. doi:
10.1111/febs.14751. [PMID: 30637949] - Hong Guo, Jie Zhang, Yaping Wang, Chen Bu, Yanyan Zhou, Qin Fang. Comparative Proteomic Analysis of Lysine Acetylation in Fish CIK Cells Infected with Aquareovirus.
International journal of molecular sciences.
2017 Nov; 18(11):. doi:
10.3390/ijms18112419. [PMID: 29135940] - Kazuki Kurita, Takuya Sakamoto, Noriyoshi Yagi, Yuki Sakamoto, Akihiro Ito, Norikazu Nishino, Kaori Sako, Minoru Yoshida, Hiroshi Kimura, Motoaki Seki, Sachihiro Matsunaga. Live imaging of H3K9 acetylation in plant cells.
Scientific reports.
2017 04; 7(?):45894. doi:
10.1038/srep45894. [PMID: 28418019] - Shanhu Qian, Lan Sun, Jiaqi Li, Junqing Wu, Gang Hu, Yixiang Han, Kang Yu, Shenghui Zhang. MAP30 inhibits autophagy through enhancing acetyltransferase p300 and induces apoptosis in acute myeloid leukemia cells.
Oncology reports.
2016 Jun; 35(6):3705-13. doi:
10.3892/or.2016.4705. [PMID: 27035419] - Dennis R Warner, Scott C Smith, Irina A Smolenkova, M Michele Pisano, Robert M Greene. Inhibition of p300 histone acetyltransferase activity in palate mesenchyme cells attenuates Wnt signaling via aberrant E-cadherin expression.
Experimental cell research.
2016 Mar; 342(1):32-8. doi:
10.1016/j.yexcr.2016.02.015. [PMID: 26921506] - Dongming Zhao, Satoshi Fukuyama, Yuko Sakai-Tagawa, Emi Takashita, Jason E Shoemaker, Yoshihiro Kawaoka. C646, a Novel p300/CREB-Binding Protein-Specific Inhibitor of Histone Acetyltransferase, Attenuates Influenza A Virus Infection.
Antimicrobial agents and chemotherapy.
2015 Dec; 60(3):1902-6. doi:
10.1128/aac.02055-15. [PMID: 26711748] - Yuhei Nishimura, Shota Sasagawa, Michiko Ariyoshi, Sayuri Ichikawa, Yasuhito Shimada, Koki Kawaguchi, Reiko Kawase, Reiko Yamamoto, Takuma Uehara, Takaaki Yanai, Ryoji Takata, Toshio Tanaka. Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity.
Frontiers in pharmacology.
2015; 6(?):199. doi:
10.3389/fphar.2015.00199. [PMID: 26441656] - Yiya Yang, Kanghan Liu, Yumei Liang, Yinyin Chen, Ying Chen, Yuting Gong. Histone acetyltransferase inhibitor C646 reverses epithelial to mesenchymal transition of human peritoneal mesothelial cells via blocking TGF-β1/Smad3 signaling pathway in vitro.
International journal of clinical and experimental pathology.
2015; 8(3):2746-54. doi:
NULL. [PMID: 26045780]
