7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one (BioDeep_00000844122)

   


代谢物信息卡片


7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one

化学式: C15H11Cl2NOS (322.99383760000006)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(=O)NC2=C(C=C(C=C2)Cl)C(S1)C3=CC=CC=C3Cl
InChI: InChI=1S/C15H11Cl2NOS/c16-9-5-6-13-11(7-9)15(20-8-14(19)18-13)10-3-1-2-4-12(10)17/h1-7,15H,8H2,(H,18,19)

描述信息

同义名列表

1 个代谢物同义名

7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

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  • Yohei Ohshima, Natsuhiko Takata, Miki Suzuki-Karasaki, Yukihiro Yoshida, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki. Disrupting mitochondrial Ca2+ homeostasis causes tumor-selective TRAIL sensitization through mitochondrial network abnormalities. International journal of oncology. 2017 Oct; 51(4):1146-1158. doi: 10.3892/ijo.2017.4096. [PMID: 28849210]
  • Vicente Lumbreras, Esperanza Bas, Chhavi Gupta, Suhrud M Rajguru. Pulsed infrared radiation excites cultured neonatal spiral and vestibular ganglion neurons by modulating mitochondrial calcium cycling. Journal of neurophysiology. 2014 Sep; 112(6):1246-55. doi: 10.1152/jn.00253.2014. [PMID: 24920028]
  • Philippe Delmotte, Binxia Yang, Michael A Thompson, Christina M Pabelick, Y S Prakash, Gary C Sieck. Inflammation alters regional mitochondrial Ca²+ in human airway smooth muscle cells. American journal of physiology. Cell physiology. 2012 Aug; 303(3):C244-56. doi: 10.1152/ajpcell.00414.2011. [PMID: 22673614]
  • Quan Hong, Ka Qi, Zhe Feng, Zhiyong Huang, Shaoyuan Cui, Liyuan Wang, Bo Fu, Rui Ding, Jurong Yang, Xiangmei Chen, Di Wu. Hyperuricemia induces endothelial dysfunction via mitochondrial Na+/Ca2+ exchanger-mediated mitochondrial calcium overload. Cell calcium. 2012 May; 51(5):402-10. doi: 10.1016/j.ceca.2012.01.003. [PMID: 22361139]
  • P C Rodriguez, M M Satorre, M T Beconi. Effect of two intracellular calcium modulators on sperm motility and heparin-induced capacitation in cryopreserved bovine spermatozoa. Animal reproduction science. 2012 Apr; 131(3-4):135-42. doi: 10.1016/j.anireprosci.2012.03.015. [PMID: 22516227]
  • Robert Zorec, Alfonso Araque, Giorgio Carmignoto, Philip G Haydon, Alexei Verkhratsky, Vladimir Parpura. Astroglial excitability and gliotransmission: an appraisal of Ca2+ as a signalling route. ASN neuro. 2012 Mar; 4(2):. doi: 10.1042/an20110061. [PMID: 22313347]
  • Petra Popovics, William Beswick, Simon B Guild, Gordon Cramb, Kevin Morgan, Robert P Millar, Alan J Stewart. Phospholipase C-η2 is activated by elevated intracellular Ca(2+) levels. Cellular signalling. 2011 Nov; 23(11):1777-84. doi: 10.1016/j.cellsig.2011.06.012. [PMID: 21740965]
  • Yi Chang, Yu-Wan Lin, Su-Jane Wang. Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A. Naunyn-Schmiedeberg's archives of pharmacology. 2011 Jul; 384(1):59-70. doi: 10.1007/s00210-011-0630-1. [PMID: 21541760]
  • Ting Liu, David A Brown, Brian O'Rourke. Role of mitochondrial dysfunction in cardiac glycoside toxicity. Journal of molecular and cellular cardiology. 2010 Nov; 49(5):728-36. doi: 10.1016/j.yjmcc.2010.06.012. [PMID: 20620145]
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  • José V Montoya G, Jhon-Jairo Sutachan, Alexandra Corrales, Fang Xu, Thomas J J Blanck, Esperanza Recio-Pinto. Pulses of extracellular K+ produce two cytosolic Ca2+ transients that display different temperature dependence and carbonyl cyanide m-chlorophenyl sensitivity in SH-SY5Y cells. Brain research. 2008 Jun; 1213(?):12-26. doi: 10.1016/j.brainres.2008.03.022. [PMID: 18448083]
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  • S L Colegrove, M A Albrecht, D D Friel. Dissection of mitochondrial Ca2+ uptake and release fluxes in situ after depolarization-evoked [Ca2+](i) elevations in sympathetic neurons. The Journal of general physiology. 2000 Mar; 115(3):351-70. doi: 10.1085/jgp.115.3.351. [PMID: 10694263]
  • M Montero, M T Alonso, E Carnicero, I Cuchillo-Ibáñez, A Albillos, A G García, J García-Sancho, J Alvarez. Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion. Nature cell biology. 2000 Feb; 2(2):57-61. doi: 10.1038/35000001. [PMID: 10655583]