Broflanilide (BioDeep_00000843995)
代谢物信息卡片
Broflanilide
化学式: C25H14BrF11N2O2 (662.0062936)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN(C1=CC=CC(=C1F)C(=O)NC2=C(C=C(C=C2Br)C(C(F)(F)F)(C(F)(F)F)F)C(F)(F)F)C(=O)C3=CC=CC=C3
InChI: InChI=1S/C25H14BrF11N2O2/c1-39(21(41)12-6-3-2-4-7-12)17-9-5-8-14(18(17)27)20(40)38-19-15(23(29,30)31)10-13(11-16(19)26)22(28,24(32,33)34)25(35,36)37/h2-11H,1H3,(H,38,40)
描述信息
Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM[1].
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代谢反应
0 个相关的代谢反应过程信息。
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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiyan Mu, Kai Wang, Lu He, Zaiteng Liu, Yining Zhang, Ru Zhang, Manman Duan, Chengju Wang. Neural System Impairment and Involved Microglia-Neuron Regulation of Broflanilide in Zebrafish Larvae.
Environmental science & technology.
2023 09; 57(38):14138-14149. doi:
10.1021/acs.est.3c03626. [PMID: 37695573] - Xingliang Wang, Tailong Shi, Ping Tang, Shengnan Liu, Bofeng Hou, Dong Jiang, Jingde Lu, Yihua Yang, Yves Carrière, Yidong Wu. Baseline susceptibility of Helicoverpa armigera, Plutella xylostella, and Spodoptera frugiperda to the meta-diamide insecticide broflanilide.
Insect science.
2023 Aug; 30(4):1118-1128. doi:
10.1111/1744-7917.13142. [PMID: 36326623] - Xin-Lian Li, Jiao Wu, Xin-Yan Cai, Dou-Dou Li, Dai-Feng Cheng, Yong-Yue Lu. Lethal and sublethal effects of broflanilide on four tephritid pests (Diptera: Tephritidae).
Pest management science.
2023 Aug; 79(8):2862-2868. doi:
10.1002/ps.7463. [PMID: 36944553] - Yichi Zhang, Qiutang Huang, Chengwang Sheng, Genyan Liu, Kexin Zhang, Zhongqiang Jia, Tao Tang, Xin Mao, Andrew K Jones, Zhaojun Han, Chunqing Zhao. G3'MTMD3 in the insect GABA receptor subunit, RDL, confers resistance to broflanilide and fluralaner.
PLoS genetics.
2023 Jun; 19(6):e1010814. doi:
10.1371/journal.pgen.1010814. [PMID: 37384781] - Nan Fang, Xueping Zhao, Yanjie Li, Yuqin Luo, Xiangyun Wang, Hongmei He, Changpeng Zhang, Jinhua Jiang. Uptake, translocation and subcellular distribution of broflanilide, afidopyropen, and flupyradifurone in mustard (Brassica juncea).
Journal of hazardous materials.
2023 06; 452(?):131381. doi:
10.1016/j.jhazmat.2023.131381. [PMID: 37030221] - Kai Wang, Wunan Che, Manman Duan, Chengju Wang, Xiuwei Li, Lu He. Effects of Broflanilide on Oxidative Stress and Expression of Apoptotic Genes in Zebrafish (Danio rerio) Gill.
Bulletin of environmental contamination and toxicology.
2023 May; 110(5):91. doi:
10.1007/s00128-023-03733-5. [PMID: 37156957] - Zhen Wang, Chenglong Li, Yuxing Wang, Zihao Chen, Minghua Wang, Haiyan Shi. Photolysis of the novel meta-diamide insecticide broflanilide in solutions: Kinetics, degradation pathway, DFT calculation and ecotoxicity assessment.
Chemosphere.
2023 Apr; 320(?):138060. doi:
10.1016/j.chemosphere.2023.138060. [PMID: 36754300] - Yunyi Li, Cheng Qu, Qinghe Zhang, Liping Zhang, Chen Luo, Ran Wang. Baseline Susceptibility, Cross-Resistance, and Sublethal Effects of Broflanilide, a Novel Meta-Diamide Pesticide, in Spodoptera litura.
International journal of molecular sciences.
2023 Mar; 24(6):. doi:
10.3390/ijms24065351. [PMID: 36982427] - Kai Wang, Yaping Liang, Manman Duan, Wunan Che, Lu He. Chronic toxicity of broflanilide in Daphnia magna: changes in molting, behavior, and gene expression.
Environmental science and pollution research international.
2023 Mar; ?(?):. doi:
10.1007/s11356-023-26255-3. [PMID: 36881221] - Jin-Cui Chen, Li-Jun Cao, Li-Na Sun, Yong-Fu Gao, Hua-Qian Cao, Zhong-Zheng Ma, Li-Jun Ma, Xiu-Jing Shen, Jia-Xu Wang, Ya-Jun Gong, Anthony Ary Hoffmann, Shu-Jun Wei. Variation in the toxicity of a novel meta-diamide insecticide, broflanilide, among thrips pest species and developmental stages.
Pest management science.
2022 Dec; 78(12):5090-5096. doi:
10.1002/ps.7124. [PMID: 36102347] - Kai Wang, Chengju Wang, Jiahong Wang, Yufei Dong, Wunan Che, Xiuwei Li. Acute toxicity of broflanilide on neurosecretory system and locomotory behavior of zebrafish (Danio rerio).
Chemosphere.
2022 Oct; 305(?):135426. doi:
10.1016/j.chemosphere.2022.135426. [PMID: 35752316] - Ning Shen, Huai-Yu Liu, Tong-Yu Mou, Yi-Bo Ma, Yao Li, Zi-Jiao Song, Tao Tang, Zhao-Jun Han, Chun-Qing Zhao. Novel meta-diamide insecticide, broflanilide, suppresses the population of common cutworm Spodoptera litura through its lethal and sublethal effects.
Pest management science.
2022 Mar; 78(3):1081-1089. doi:
10.1002/ps.6719. [PMID: 34786809] - Xi Sun, Rui Wei, Linhong Li, Bin Zhu, Pei Liang, Xiwu Gao. Resistance and fitness costs in diamondback moths after selection using broflanilide, a novel meta-diamide insecticide.
Insect science.
2022 Feb; 29(1):188-198. doi:
10.1111/1744-7917.12917. [PMID: 33860634] - Manman Duan, Jie Zhang, Jia Liu, Le Qian, Xiangguang Chen, Feng Zhao, Wentian Zhao, Zhaomin Zhong, Yang Yang, Chengju Wang. Toxic effects of broflanilide exposure on development of zebrafish (Danio rerio) embryos and its potential cardiotoxicity mechanism.
Environmental pollution (Barking, Essex : 1987).
2021 Oct; 286(?):117481. doi:
10.1016/j.envpol.2021.117481. [PMID: 34126520] - Ning Shen, Yao Li, Kipchoge Leviticus, Xiao Li Chang, Tao Tang, Li Cui, Zhao Jun Han, Chun Qing Zhao. Effect of broflanilide on the phytophagous mite Tetranychus urticae and the predatory mite Typhlodromips swirskii.
Pest management science.
2021 Jun; 77(6):2964-2970. doi:
10.1002/ps.6335. [PMID: 33624401] - Tao Tang, Fang Hu, Pei Wang, Wei Fu, Xueyuan Liu. Broflanilide effectively controls Helicoverpa armigera and Spodoptera exigua exhibiting diverse susceptibilities to chlorantraniliprole and emamectin benzoate.
Pest management science.
2021 Mar; 77(3):1262-1272. doi:
10.1002/ps.6139. [PMID: 33063419] - Ya Gao, Yichi Zhang, Fengshou Wu, Jianfeng Pei, Xiaogang Luo, Xiulian Ju, Chunqing Zhao, Genyan Liu. Exploring the Interaction Mechanism of Desmethyl-broflanilide in Insect GABA Receptors and Screening Potential Antagonists by In Silico Simulations.
Journal of agricultural and food chemistry.
2020 Dec; 68(50):14768-14780. doi:
10.1021/acs.jafc.0c05728. [PMID: 33274636] - Zhong-Qiang Jia, Yi-Chi Zhang, Qiu-Tang Huang, Andrew K Jones, Zhao-Jun Han, Chun-Qing Zhao. Acute toxicity, bioconcentration, elimination, action mode and detoxification metabolism of broflanilide in zebrafish, Danio rerio.
Journal of hazardous materials.
2020 07; 394(?):122521. doi:
10.1016/j.jhazmat.2020.122521. [PMID: 32279005]