5,6-Dihydroxy-3-phenyl-1-aminomethylisochroman (BioDeep_00000843933)
代谢物信息卡片
化学式: C16H17NO3 (271.1208372)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(OC(C2=C1C(=C(C=C2)O)O)CN)C3=CC=CC=C3
InChI: InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1
描述信息
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Jing-Yuan Cao, Le-Ting Zhou, Zuo-Lin Li, Yan Yang, Bi-Cheng Liu, Hong Liu. Dopamine D1 receptor agonist A68930 attenuates acute kidney injury by inhibiting NLRP3 inflammasome activation.
Journal of pharmacological sciences.
2020 Jul; 143(3):226-233. doi:
10.1016/j.jphs.2020.04.005
. [PMID: 32446726] - Paweł Mystek, Magdalena Tworzydło, Marta Dziedzicka-Wasylewska, Agnieszka Polit. New insights into the model of dopamine D1 receptor and G-proteins interactions.
Biochimica et biophysica acta.
2015 Mar; 1853(3):594-603. doi:
10.1016/j.bbamcr.2014.12.015
. [PMID: 25527226] - Naila Rasheed, Ausaf Ahmad, Muneera Al-Sheeha, Abdullah Alghasham, Gautam Palit. Neuroprotective and anti-stress effect of A68930 in acute and chronic unpredictable stress model in rats.
Neuroscience letters.
2011 Oct; 504(2):151-155. doi:
10.1016/j.neulet.2011.09.021
. [PMID: 21945949] - Hiroki Nakashioya, Kazuhisa Nakano, Naoko Watanabe, Nobuyuki Miyasaka, Sho Matsushita, Hitoshi Kohsaka. Therapeutic effect of D1-like dopamine receptor antagonist on collagen-induced arthritis of mice.
Modern rheumatology.
2011 Jun; 21(3):260-6. doi:
10.1007/s10165-010-0387-2
. [PMID: 21188452] - Naila Rasheed, Ausaf Ahmad, Neetu Singh, Pratibha Singh, Vaibhav Mishra, Naheed Banu, Mohtashim Lohani, Sharad Sharma, Gautam Palit. Differential response of A 68930 and sulpiride in stress-induced gastric ulcers in rats.
European journal of pharmacology.
2010 Sep; 643(1):121-8. doi:
10.1016/j.ejphar.2010.06.032
. [PMID: 20599913] - Jessica P Ryman-Rasmussen, David E Nichols, Richard B Mailman. Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists.
Molecular pharmacology.
2005 Oct; 68(4):1039-48. doi:
10.1124/mol.105.012153
. [PMID: 15985612] - M I Christie, G W Smith. Cardiovascular and renal hemodynamic effects of A-68930 in the conscious dog: a comparison with fenoldopam.
The Journal of pharmacology and experimental therapeutics.
1994 Feb; 268(2):565-70. doi:
NULL
. [PMID: 7906731] - A Grenader, D P Healy. A68930 is a potent, full agonist at dopamine1 (D1) receptors in renal epithelial LLC-PK1 cells.
British journal of pharmacology.
1992 Jun; 106(2):229-30. doi:
10.1111/j.1476-5381.1992.tb14320.x
. [PMID: 1356555]