Evans blue free acid (BioDeep_00000843928)
代谢物信息卡片
Evans blue free acid
化学式: C34H28N6O14S4 (872.0546308)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C3)C(=CC(=C4N)S(=O)(=O)O)S(=O)(=O)O)O)C)N=NC5=C(C6=C(C=C5)C(=CC(=C6N)S(=O)(=O)O)S(=O)(=O)O)O
InChI: InChI=1S/C34H28N6O14S4/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:87634
- PubChem: 3315
- ChEMBL: CHEMBL1607905
- ChEMBL: CHEMBL1015
- MeSH: Evans Blue
- CAS: 6968-33-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
13 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(13)
- Purine Ribonucleosides Degradation:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - O-Antigen Building Blocks Biosynthesis:
-D-fructofuranose 6-phosphate + L-Glutamine ⟶ D-glucosamine 6-phosphate + L-Glutamic acid - O-Antigen Building Blocks Biosynthesis:
-D-fructofuranose 6-phosphate + L-Glutamine ⟶ D-glucosamine 6-phosphate + L-Glutamic acid - Biotin Metabolism:
Dethiobiotin + Hydrogen Ion + S-Adenosylmethionine + a sulfurated [sulfur carrier] ⟶ 5'-Deoxyadenosine + Biotin + L-Methionine - Biotin Metabolism:
Adenosine triphosphate + Biotin ⟶ Biotinyl-5'-AMP + diphosphate - L-Carnitine Degradation I:
Adenosine triphosphate + Coenzyme A + L-Carnitine ⟶ Adenosine monophosphate + L-Carnitinyl-CoA + diphosphate - L-Carnitine Degradation I:
Adenosine triphosphate + Coenzyme A + L-Carnitine ⟶ Adenosine monophosphate + L-Carnitinyl-CoA + diphosphate - Guanylyl Molybdenum Cofactor Biosynthesis:
Guanosine triphosphate + Hydrogen Ion + Molybdopterin guanine dinucleotide ⟶ Guanylyl molybdenum cofactor + diphosphate - Enterobactin Biosynthesis:
(2,3-Dihydroxybenzoyl)adenylic acid + a holo-[EntB isochorismatase/aryl-carrier protein] ⟶ Adenosine monophosphate + Hydrogen Ion + a 2,3-dihydroxybenzoyl-[EntB isochorismatase/aryl-carrier protein] - Enterobactin Biosynthesis:
(2,3-Dihydroxybenzoyl)adenylic acid + a holo-[EntB isochorismatase/aryl-carrier protein] ⟶ Adenosine monophosphate + Hydrogen Ion + a 2,3-dihydroxybenzoyl-[EntB isochorismatase/aryl-carrier protein] - 1,6-Anhydro-N-acetylmuramic Acid Recycling:
N-Acetyl-D-Glucosamine 6-Phosphate + Water ⟶ Acetic acid + D-glucosamine 6-phosphate - 1,6-Anhydro-N-acetylmuramic Acid Recycling:
N-Acetyl-D-Glucosamine 6-Phosphate + Water ⟶ Acetic acid + D-glucosamine 6-phosphate - ADP-L-glycero-beta-D-manno-heptose Biosynthesis:
Adenosine triphosphate + D-glycero-D-manno-heptose 7-phosphate ⟶ Adenosine diphosphate + D-glycero- -D-manno-heptose 1,7-bisphosphate + Hydrogen Ion
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shu-Qi Yao, Yang Ye, Quan Li, Xiao-Yi Wang, Li Yan, Xin-Mei Huo, Chun-Shui Pan, Yu Fu, Jian Liu, Jing-Yan Han. YangXueQingNaoWan attenuated blood brain barrier disruption after thrombolysis with tissue plasminogen activator in ischemia stroke.
Journal of ethnopharmacology.
2024 Jan; 318(Pt B):117024. doi:
10.1016/j.jep.2023.117024. [PMID: 37572928] - Jing Yan, Zehua Li, Yu Liang, Chaobo Yang, Wen Ou, Huaqiang Mo, Min Tang, Deshu Chen, Chongbin Zhong, Dongdong Que, Liyun Feng, Hua Xiao, Xudong Song, Pingzhen Yang. Fucoxanthin alleviated myocardial ischemia and reperfusion injury through inhibition of ferroptosis via the NRF2 signaling pathway.
Food & function.
2023 Nov; 14(22):10052-10068. doi:
10.1039/d3fo02633g. [PMID: 37861458] - Rui-Bin Hu, Meng-Yang Long, Zhi-Jun Diao, Yu-Wei Wu, Si-Meng Xue, Xin-Yan Gao, Hai-Fa Qiao. [Relationship between acupoint sensitization and changes in dorsal root ganglion neuron excitability in myocardial ischemia mice].
Zhen ci yan jiu = Acupuncture research.
2023 Sep; 48(9):833-42. doi:
10.13702/j.1000-0607.20221049. [PMID: 37730253] - Juan Huang, Jianhao Zhou, Yujie Dai, Yuankai Liu, Fang Li, Shuaishuai Gong, Yuanyuan Zhang, Junping Kou. Ruscogenin ameliorates dasatinib-induced intestinal barrier dysfunction via ErbB4/YAP and ROCK/MLC pathways.
Journal of natural medicines.
2023 Sep; 77(4):735-747. doi:
10.1007/s11418-023-01715-9. [PMID: 37347409] - Qian Li, Ziyan Tang, Yuanyuan Zhang, Tianyu Yuan, Bochuan Yuan, Lina Du, Yiguang Jin. Application of low-intensity ultrasound by opening blood-brain barrier for enhanced brain-targeted drug delivery.
International journal of pharmaceutics.
2023 Jul; 642(?):123191. doi:
10.1016/j.ijpharm.2023.123191. [PMID: 37391108] - Ligema Dao, Li Jiang, Yuanyuan Chen, Ayisa, Chula Sa. Study on the opening effect of eucalyptol on the blood-brain barrier and its brain pharmacokinetics.
Biomedical chromatography : BMC.
2023 Jun; 37(6):e5631. doi:
10.1002/bmc.5631. [PMID: 36987546] - Cevahir Altinkaynak, Merve Turk, Nazlican Yangin, Nalan Özdemir. A Novel Biomaterial for Decolorization of Azo Dyes: Myoglobin-Zn(II) Assisted Hybrid Nanoflowers.
Chemistry & biodiversity.
2023 Jun; 20(6):e202201136. doi:
10.1002/cbdv.202201136. [PMID: 37130149] - Si-Jia Liu, Jun-Tong Liu, Ji-Quan Li, Cheng-Cheng Wang, Miao Yu, Zhi-Qiang Guan, Lie Wang, Tie-Ming Ma. [Effect of acupuncture pretreatment of "Quchi"(LI11) and "Xuehai" (SP10) on mast cells and IL-33/ST2 in rats with urticaria].
Zhen ci yan jiu = Acupuncture research.
2023 Apr; 48(4):311-6. doi:
10.13702/j.1000-0607.20211282. [PMID: 37186193] - Q Yuan, L Xie, C Chen. [Astragalus polysaccharide protects against blood-brain barrier damage in MCAO rats by inhibiting P2X7R channel].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2022 Nov; 42(11):1705-1711. doi:
10.12122/j.issn.1673-4254.2022.11.15. [PMID: 36504064] - Bingbing Han, Yangang Zhao, Jing Yao, Na Li, Tianhe Fang, Yuan Wang, Zhaoqing Meng, Wei Liu. Proteomics on the role of muscone in the "consciousness-restoring resuscitation" effect of musk on ischemic stroke.
Journal of ethnopharmacology.
2022 Oct; 296(?):115475. doi:
10.1016/j.jep.2022.115475. [PMID: 35718056] - Katarzyna Matyszczuk, Anna Krzepiłko. Model Study for Interaction of Sublethal Doses of Zinc Oxide Nanoparticles with Environmentally Beneficial Bacteria Bacillus thuringiensis and Bacillus megaterium.
International journal of molecular sciences.
2022 Oct; 23(19):. doi:
10.3390/ijms231911820. [PMID: 36233126] - Qiang Wen, Qian Ding, Jinchao Wang, Yanhua Yin, Shangchen Xu, Yuanrong Ju, Hongsheng Ji, Bin Liu. Cortistatin-14 Exerts Neuroprotective Effect Against Microglial Activation, Blood-brain Barrier Disruption, and Cognitive Impairment in Sepsis-associated Encephalopathy.
Journal of immunology research.
2022; 2022(?):3334145. doi:
10.1155/2022/3334145. [PMID: 36148090] - Meng-Chih Wu, Jye-Lin Hsu, Ted Weita Lai. Evans blue dye as an indicator of albumin permeability across a brain endothelial cell monolayer in vitro.
Neuroreport.
2021 08; 32(11):957-964. doi:
10.1097/wnr.0000000000001690. [PMID: 34227616] - Heribert Hänscheid, Philipp E Hartrampf, Andreas Schirbel, Andreas K Buck, Constantin Lapa. Intraindividual comparison of [177Lu]Lu-DOTA-EB-TATE and [177Lu]Lu-DOTA-TOC.
European journal of nuclear medicine and molecular imaging.
2021 07; 48(8):2566-2572. doi:
10.1007/s00259-020-05177-z. [PMID: 33452632] - Christopher J Day, Benjamin Bailly, Patrice Guillon, Larissa Dirr, Freda E-C Jen, Belinda L Spillings, Johnson Mak, Mark von Itzstein, Thomas Haselhorst, Michael P Jennings. Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2-ACE2 Receptor Interactions.
mBio.
2021 03; 12(2):. doi:
10.1128/mbio.03681-20. [PMID: 33785634] - Samuel E Honeycutt, Lori L O'Brien. Injection of Evans blue dye to fluorescently label and image intact vasculature.
BioTechniques.
2021 03; 70(3):181-185. doi:
10.2144/btn-2020-0152. [PMID: 33337254] - Ji Youn Lee, Ho Young Kim, Yun-Sang Lee, Hye Yeon Seo, Ji Yong Park, Jae Min Jeong. Preparation of a multi-modal agent for sentinel lymph node mapping using Evans blue and 99mTc-labeled mannosylated human serum albumin conjugate.
Nuclear medicine and biology.
2020 May; 84-85(?):38-45. doi:
10.1016/j.nucmedbio.2020.02.002. [PMID: 32044560] - Ding Ding, Cai Yang, Cheng Lv, Juan Li, Weihong Tan. Improving Tumor Accumulation of Aptamers by Prolonged Blood Circulation.
Analytical chemistry.
2020 03; 92(5):4108-4114. doi:
10.1021/acs.analchem.9b05878. [PMID: 32037790] - Dong Lin, Shi Yi Qi, Lin Hong, Shen Lin, Li Li Lin, Yu Chang Mo. [Multivariate statistical analysis of Evans blue exudation spots and acupoint sensitization distribution in rats with acute intestinal mucosal injury].
Zhen ci yan jiu = Acupuncture research.
2020 Feb; 45(2):128-35. doi:
10.13702/j.1000-0607.1904526. [PMID: 32144923] - T V Schäfer, Ju Ju Ivnitsky, V L Rejniuk. Permeability of Intestinal and Blood-Tissue Barriers in Rats for Evans Blue Dye under Conditions of Acute Intoxication with Cyclophosphamide.
Bulletin of experimental biology and medicine.
2019 Nov; 168(1):38-40. doi:
10.1007/s10517-019-04640-8. [PMID: 31748869] - M W Harding, T B Hill, Y Yang, G C Daniels, S F Hwang, S E Strelkov, R J Howard, J Feng. An Improved Evans Blue Staining Method for Consistent, Accurate Assessment of Plasmodiophora brassicae Resting Spore Viability.
Plant disease.
2019 Sep; 103(9):2330-2336. doi:
10.1094/pdis-05-18-0855-re. [PMID: 31298992] - Rui Tian, Shoujun Zhu, Qiao Zeng, Lixin Lang, Ying Ma, Dale O Kiesewetter, Yi Liu, Xiao Fu, Joseph Lau, Guizhi Zhu, Orit Jacobson, Zhantong Wang, Yunlu Dai, Guocan Yu, Bernard R Brooks, Gang Liu, Gang Niu, Xiaoyuan Chen. An Albumin Sandwich Enhances in Vivo Circulation and Stability of Metabolically Labile Peptides.
Bioconjugate chemistry.
2019 06; 30(6):1711-1723. doi:
10.1021/acs.bioconjchem.9b00258. [PMID: 31082207] - Hari Shanker Sharma, Dafin Fior Muresanu, Ala Nozari, Rudy J Castellani, Prasanta Kumar Dey, Lars Wiklund, Aruna Sharma. Anesthetics influence concussive head injury induced blood-brain barrier breakdown, brain edema formation, cerebral blood flow, serotonin levels, brain pathology and functional outcome.
International review of neurobiology.
2019; 146(?):45-81. doi:
10.1016/bs.irn.2019.06.006. [PMID: 31349932] - Michael S Wolf, Yaming Chen, Dennis W Simon, Henry Alexander, Mark Ross, Gregory A Gibson, Miora D Manole, Hülya Bayır, Patrick M Kochanek, Robert S B Clark. Quantitative and qualitative assessment of glymphatic flux using Evans blue albumin.
Journal of neuroscience methods.
2019 01; 311(?):436-441. doi:
10.1016/j.jneumeth.2018.09.031. [PMID: 30292824] - Claudia Tallian, Alexandra Herrero-Rollett, Karina Stadler, Robert Vielnascher, Karin Wieland, Anna M Weihs, Alessandro Pellis, Andreas H Teuschl, Bernhard Lendl, Heinz Amenitsch, Georg M Guebitz. Structural insights into pH-responsive drug release of self-assembling human serum albumin-silk fibroin nanocapsules.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2018 Dec; 133(?):176-187. doi:
10.1016/j.ejpb.2018.10.002. [PMID: 30291964] - Jean-Paul Richalet, Dominique Marchant, Jose-Luis Macarlupu, Nicolas Voituron. Modeling the Evans Blue Dilution Method for the Measurement of Plasma Volume in Small Animals: A New Optimized Method.
Annals of biomedical engineering.
2018 Dec; 46(12):2189-2195. doi:
10.1007/s10439-018-02114-y. [PMID: 30136152] - Jingjing Zhang, Hao Wang, Orit Jacobson, Yuejuan Cheng, Gang Niu, Fang Li, Chunmei Bai, Zhaohui Zhu, Xiaoyuan Chen. Safety, Pharmacokinetics, and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analog 177Lu-DOTA-EB-TATE in Patients with Advanced Metastatic Neuroendocrine Tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2018 11; 59(11):1699-1705. doi:
10.2967/jnumed.118.209841. [PMID: 29653971] - Mária Mészáros, Gergő Porkoláb, Lóránd Kiss, Ana-Maria Pilbat, Zoltán Kóta, Zoltán Kupihár, Albert Kéri, Gábor Galbács, László Siklós, András Tóth, Lívia Fülöp, Mária Csete, Áron Sipos, Petra Hülper, Péter Sipos, Tibor Páli, Gábor Rákhely, Piroska Szabó-Révész, Mária A Deli, Szilvia Veszelka. Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2018 Oct; 123(?):228-240. doi:
10.1016/j.ejps.2018.07.042. [PMID: 30031862] - Marilee J Wick, Julie W Harral, Zoe L Loomis, Edward C Dempsey. An Optimized Evans Blue Protocol to Assess Vascular Leak in the Mouse.
Journal of visualized experiments : JoVE.
2018 09; ?(139):. doi:
10.3791/57037. [PMID: 30272649] - Hwai-Lee Wang, Eva Yuhua Kuo, Ted Weita Lai. Vascular delivery of intraperitoneal Evans blue dye into the blood-brain barrier-intact and disrupted rat brains.
Neuroreport.
2018 08; 29(11):924-931. doi:
10.1097/wnr.0000000000001052. [PMID: 29762248] - Anton A Namykin, Natalia A Shushunova, Maria V Ulanova, Oxana V Semyachkina-Glushkovskaya, Valery V Tuchin, Ivan V Fedosov. Intravital molecular tagging velocimetry of cerebral blood flow using Evans Blue.
Journal of biophotonics.
2018 08; 11(8):e201700343. doi:
10.1002/jbio.201700343. [PMID: 29603902] - Marcela Maloveska, Jan Danko, Eva Petrovova, Lenka Kresakova, Katarina Vdoviakova, Alena Michalicova, Andrej Kovac, Veronika Cubinkova, Dasa Cizkova. Dynamics of Evans blue clearance from cerebrospinal fluid into meningeal lymphatic vessels and deep cervical lymph nodes.
Neurological research.
2018 May; 40(5):372-380. doi:
10.1080/01616412.2018.1446282. [PMID: 29619904] - Andreas Margraf, Jan M Herter, Katharina Kühne, Anika Stadtmann, Thomas Ermert, Manuel Wenk, Melanie Meersch, Hugo Van Aken, Alexander Zarbock, Jan Rossaint. 6\% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice.
Critical care (London, England).
2018 May; 22(1):111. doi:
10.1186/s13054-017-1846-3. [PMID: 29716625] - Shih-Chieh Chen, Chao-Yuah Chang, Ming-Lu Lin. Vascular Hyperpermeability Response in Animals Systemically Exposed to Arsenic.
International journal of medical sciences.
2018; 15(5):425-429. doi:
10.7150/ijms.23480. [PMID: 29559830] - Akihiro Tojo, Saaya Hatakeyama, Satoshi Kinugasa, Satoru Fukuda, Toshio Sakai. Enhanced podocyte vesicle transport in the nephrotic rat.
Medical molecular morphology.
2017 Jun; 50(2):86-93. doi:
10.1007/s00795-016-0151-6. [PMID: 28314927] - Wei He, Xiao-Yu Wang, Hong Shi, Wan-Zhu Bai, Bin Cheng, Yang-Shuai Su, Xiao-Chun Yu, Xiang-Hong Jing, Bing Zhu. Cutaneous neurogenic inflammation in the sensitized acupoints induced by gastric mucosal injury in rats.
BMC complementary and alternative medicine.
2017 Mar; 17(1):141. doi:
10.1186/s12906-017-1580-z. [PMID: 28270193] - Sungsu Lee, Wonbong Lim, Hye-Won Ryu, Danbi Jo, Jung-Joon Min, Hyung-Seok Kim, Hoon Hyun. ZW800-1 for Assessment of Blood-Brain Barrier Disruption in a Photothrombotic Stroke Model.
International journal of medical sciences.
2017; 14(13):1430-1435. doi:
10.7150/ijms.22294. [PMID: 29200957] - O M Rodionova, V V Glebov, E V Artamonova, M A Butenin, E V Anikina. Effect of Herbal Homeopathic Monopreparations on the Rate of Tissue Lymphatic Drainage in Healthy Mice.
Bulletin of experimental biology and medicine.
2016 Oct; 161(6):786-787. doi:
10.1007/s10517-016-3510-3. [PMID: 27783290] - Yufeng Zhou, Yak-Nam Wang, Navid Farr, Jasmine Zia, Hong Chen, Bong Min Ko, Tatiana Khokhlova, Tong Li, Joo Ha Hwang. Enhancement of Small Molecule Delivery by Pulsed High-Intensity Focused Ultrasound: A Parameter Exploration.
Ultrasound in medicine & biology.
2016 Apr; 42(4):956-63. doi:
10.1016/j.ultrasmedbio.2015.12.009. [PMID: 26803389] - Chengliang Sun, Lingli Lu, Yan Yu, Lijuan Liu, Yan Hu, Yiquan Ye, Chongwei Jin, Xianyong Lin. Decreasing methylation of pectin caused by nitric oxide leads to higher aluminium binding in cell walls and greater aluminium sensitivity of wheat roots.
Journal of experimental botany.
2016 Feb; 67(3):979-89. doi:
10.1093/jxb/erv514. [PMID: 26663393] - Ban Liu, Chao-Peng Li, Wen-Qi Wang, Shu-Guang Song, Xiu-Ming Liu. Lignans Extracted from Eucommia Ulmoides Oliv. Protects Against AGEs-Induced Retinal Endothelial Cell Injury.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2016; 39(5):2044-2054. doi:
10.1159/000447900. [PMID: 27825165] - Zijian Zhao, Jing Xiao, Jiancheng Wang, Wanrong Dong, Zhihong Peng, Delie An. Anti-inflammatory effects of novel sinomenine derivatives.
International immunopharmacology.
2015 Dec; 29(2):354-360. doi:
10.1016/j.intimp.2015.10.030. [PMID: 26525983] - Dafin F Muresanu, Aruna Sharma, José V Lafuente, Ranjana Patnaik, Z Ryan Tian, Fred Nyberg, Hari S Sharma. Nanowired Delivery of Growth Hormone Attenuates Pathophysiology of Spinal Cord Injury and Enhances Insulin-Like Growth Factor-1 Concentration in the Plasma and the Spinal Cord.
Molecular neurobiology.
2015 Oct; 52(2):837-45. doi:
10.1007/s12035-015-9298-8. [PMID: 26126514] - Aruna Sharma, Dafin F Muresanu, José V Lafuente, Ranjana Patnaik, Z Ryan Tian, Anca D Buzoianu, Hari S Sharma. Sleep Deprivation-Induced Blood-Brain Barrier Breakdown and Brain Dysfunction are Exacerbated by Size-Related Exposure to Ag and Cu Nanoparticles. Neuroprotective Effects of a 5-HT3 Receptor Antagonist Ondansetron.
Molecular neurobiology.
2015 Oct; 52(2):867-81. doi:
10.1007/s12035-015-9236-9. [PMID: 26133300] - Yaw-Syan Fu, Su-Yu Kuo, Hsuan-Yea Lin, Chun-Lin Chen, Shi-Ying Huang, Zhi-Hong Wen, Kun-Zer Lee, Hung-Tu Huang. Pretreatment with Evans blue, a stimulator of BK(Ca) channels, inhibits compound 48/80-induced shock, systemic inflammation, and mast cell degranulation in the rat.
Histochemistry and cell biology.
2015 Sep; 144(3):237-47. doi:
10.1007/s00418-015-1332-4. [PMID: 26003544] - Rajiv Rose, Harold G Klemcke. Relationship between Plasma Albumin Concentration and Plasma Volume in 5 Inbred Rat Strains.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2015 Sep; 54(5):459-64. doi:
NULL. [PMID: 26424242] - Christine Weinl, Salvador Castaneda Vega, Heidemarie Riehle, Christine Stritt, Carsten Calaminus, Hartwig Wolburg, Susanne Mauel, Angele Breithaupt, Achim D Gruber, Bohdan Wasylyk, Eric N Olson, Ralf H Adams, Bernd J Pichler, Alfred Nordheim. Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke.
Proceedings of the National Academy of Sciences of the United States of America.
2015 Aug; 112(32):9914-9. doi:
10.1073/pnas.1509047112. [PMID: 26221020] - Vinicius Rocha-Santos, Estela R R Figueira, Joel A Rocha-Filho, Ana M M Coelho, Rafael Soraes Pinheiro, Telesforo Bacchella, Marcel C C Machado, Luiz A C D'Albuquerque. Pentoxifylline enhances the protective effects of hypertonic saline solution on liver ischemia reperfusion injury through inhibition of oxidative stress.
Hepatobiliary & pancreatic diseases international : HBPD INT.
2015 Apr; 14(2):194-200. doi:
10.1016/s1499-3872(15)60348-4. [PMID: 25865693] - Erik Lundeberg, Anne M Van Der Does, Ellinor Kenne, Oliver Soehnlein, Lennart Lindbom. Assessing large-vessel endothelial permeability using near-infrared fluorescence imaging--brief report.
Arteriosclerosis, thrombosis, and vascular biology.
2015 Apr; 35(4):783-6. doi:
10.1161/atvbaha.114.305131. [PMID: 25675996] - Anchel González-Barriga, Julia Kranzen, Huib J E Croes, Suzanne Bijl, Walther J A A van den Broek, Ingeborg D G van Kessel, Baziel G M van Engelen, Judith C T van Deutekom, Bé Wieringa, Susan A M Mulders, Derick G Wansink. Cell membrane integrity in myotonic dystrophy type 1: implications for therapy.
PloS one.
2015; 10(3):e0121556. doi:
10.1371/journal.pone.0121556. [PMID: 25799359] - Adrian Frister, Caroline Schmidt, Nadine Schneble, Michael Brodhun, Falk A Gonnert, Michael Bauer, Emilio Hirsch, Jörg P Müller, Reinhard Wetzker, Reinhard Bauer. Phosphoinositide 3-kinase γ affects LPS-induced disturbance of blood-brain barrier via lipid kinase-independent control of cAMP in microglial cells.
Neuromolecular medicine.
2014 Dec; 16(4):704-13. doi:
10.1007/s12017-014-8320-z. [PMID: 25033932] - Shunichi Sato, Ken Yoshida, Satoko Kawauchi, Kazue Hosoe, Yusuke Akutsu, Norihiro Fujimoto, Hiroshi Nawashiro, Mitsuhiro Terakawa. Highly site-selective transvascular drug delivery by the use of nanosecond pulsed laser-induced photomechanical waves.
Journal of controlled release : official journal of the Controlled Release Society.
2014 Oct; 192(?):228-35. doi:
10.1016/j.jconrel.2014.07.048. [PMID: 25102403] - Wen-Yen Chai, Po-Chun Chu, Meng-Yen Tsai, Yu-Chun Lin, Jiun-Jie Wang, Kuo-Chen Wei, Yau-Yau Wai, Hao-Li Liu. Magnetic-resonance imaging for kinetic analysis of permeability changes during focused ultrasound-induced blood-brain barrier opening and brain drug delivery.
Journal of controlled release : official journal of the Controlled Release Society.
2014 Oct; 192(?):1-9. doi:
10.1016/j.jconrel.2014.06.023. [PMID: 24969355] - Hwai-Lee Wang, Ted Weita Lai. Optimization of Evans blue quantitation in limited rat tissue samples.
Scientific reports.
2014 Oct; 4(?):6588. doi:
10.1038/srep06588. [PMID: 25300427] - Shih-Chieh Chen, Shin-Yin Huang, Chi-Yu Lu, Ya-Hung Hsu, Dean-Chuan Wang. Microvascular dysfunction with increased vascular leakage response in mice systemically exposed to arsenic.
Cardiovascular toxicology.
2014 Sep; 14(3):222-31. doi:
10.1007/s12012-014-9246-2. [PMID: 24448713] - Trent A Waugh, Eric Horstick, Junguk Hur, Samuel W Jackson, Ann E Davidson, Xingli Li, James J Dowling. Fluoxetine prevents dystrophic changes in a zebrafish model of Duchenne muscular dystrophy.
Human molecular genetics.
2014 Sep; 23(17):4651-62. doi:
10.1093/hmg/ddu185. [PMID: 24760771] - Yi Zhang, Chuan Ye, Yali Xu, Xuexin Dong, Jianping Li, Rong Liu, Yunhua Gao. Ultrasound-mediated microbubble destruction increases renal interstitial capillary permeability in early diabetic nephropathy rats.
Ultrasound in medicine & biology.
2014 Jun; 40(6):1273-81. doi:
10.1016/j.ultrasmedbio.2013.12.006. [PMID: 24613211] - Hung-Chin Tsai, Yen-Lin Huang, Yao-Shen Chen, Chuan-Min Yen, Rachel Tsai, Susan Shin-Jung Lee, Ming-Hong Tai. 14-3-3β protein expression in eosinophilic meningitis caused by Angiostrongylus cantonensis infection.
BMC research notes.
2014 Feb; 7(?):97. doi:
10.1186/1756-0500-7-97. [PMID: 24555778] - Shaohua Liao, Bo Pan, Hao Li, Di Zhang, Baoshan Xing. Detecting free radicals in biochars and determining their ability to inhibit the germination and growth of corn, wheat and rice seedlings.
Environmental science & technology.
2014; 48(15):8581-7. doi:
10.1021/es404250a. [PMID: 24988274] - Yohei Nanjo, Takuji Nakamura, Setsuko Komatsu. Identification of indicator proteins associated with flooding injury in soybean seedlings using label-free quantitative proteomics.
Journal of proteome research.
2013 Nov; 12(11):4785-98. doi:
10.1021/pr4002349. [PMID: 23659366] - Isabel Pardo, Xiomara Chanagá, Ana Isabel Vicente, Miguel Alcalde, Susana Camarero. New colorimetric screening assays for the directed evolution of fungal laccases to improve the conversion of plant biomass.
BMC biotechnology.
2013 Oct; 13(?):90. doi:
10.1186/1472-6750-13-90. [PMID: 24159930] - R Lyle Hood, Rudy T Andriani, Samantha Emch, John L Robertson, Christopher G Rylander, John H Rossmeisl. Fiberoptic microneedle device facilitates volumetric infusate dispersion during convection-enhanced delivery in the brain.
Lasers in surgery and medicine.
2013 Sep; 45(7):418-26. doi:
10.1002/lsm.22156. [PMID: 23861185] - Eduardo Souza-Silva, Daniel Teixeira de Oliveira, Carolina Eto, Taciane Stein, Carlos Rogério Tonussi. Histamine produces opposing effects to serotonin in the knee joint of rats.
The journal of pain.
2013 Aug; 14(8):808-17. doi:
10.1016/j.jpain.2013.02.006. [PMID: 23642410] - Henry Puerta-Guardo, Arturo Raya-Sandino, Lorenza González-Mariscal, Victor H Rosales, José Ayala-Dávila, Bibiana Chávez-Mungía, Daniel Martínez-Fong, Fernando Medina, Juan E Ludert, Rosa María del Angel. The cytokine response of U937-derived macrophages infected through antibody-dependent enhancement of dengue virus disrupts cell apical-junction complexes and increases vascular permeability.
Journal of virology.
2013 Jul; 87(13):7486-501. doi:
10.1128/jvi.00085-13. [PMID: 23616663] - Camila Z El-Kik, Fabrício F A Fernandes, Marcelo Amorim Tomaz, Glauco A Gaban, Tatiane F Fonseca, Sabrina Calil-Elias, Suellen D S Oliveira, Claudia L M Silva, Ana Maria Blanco Martinez, Paulo A Melo. Neutralization of Apis mellifera bee venom activities by suramin.
Toxicon : official journal of the International Society on Toxinology.
2013 Jun; 67(?):55-62. doi:
10.1016/j.toxicon.2013.02.007. [PMID: 23474269] - Kei-ichiro Mishiba, Yukihiro Nagashima, Eiji Suzuki, Noriko Hayashi, Yoshiyuki Ogata, Yukihisa Shimada, Nozomu Koizumi. Defects in IRE1 enhance cell death and fail to degrade mRNAs encoding secretory pathway proteins in the Arabidopsis unfolded protein response.
Proceedings of the National Academy of Sciences of the United States of America.
2013 Apr; 110(14):5713-8. doi:
10.1073/pnas.1219047110. [PMID: 23509268] - Annette von Drygalski, Christian Furlan-Freguia, Wolfram Ruf, John H Griffin, Laurent O Mosnier. Organ-specific protection against lipopolysaccharide-induced vascular leak is dependent on the endothelial protein C receptor.
Arteriosclerosis, thrombosis, and vascular biology.
2013 Apr; 33(4):769-76. doi:
10.1161/atvbaha.112.301082. [PMID: 23393392] - R Lyle Hood, John H Rossmeisl, Rudy T Andriani, Ashley R Wilkinson, John L Robertson, Christopher G Rylander. Intracranial hyperthermia through local photothermal heating with a fiberoptic microneedle device.
Lasers in surgery and medicine.
2013 Mar; 45(3):167-74. doi:
10.1002/lsm.22117. [PMID: 23390044] - Jia Liu, Allen C Clermont, Ben-Bo Gao, Edward P Feener. Intraocular hemorrhage causes retinal vascular dysfunction via plasma kallikrein.
Investigative ophthalmology & visual science.
2013 Feb; 54(2):1086-94. doi:
10.1167/iovs.12-10537. [PMID: 23299478] - Shi Jin, Xin-Ting Wang, Li Liu, Dan Yao, Can Liu, Mian Zhang, Hai-Fang Guo, Xiao-Dong Liu. P-glycoprotein and multidrug resistance-associated protein 2 are oppositely altered in brain of rats with thioacetamide-induced acute liver failure.
Liver international : official journal of the International Association for the Study of the Liver.
2013 Feb; 33(2):274-82. doi:
10.1111/j.1478-3231.2012.02862.x. [PMID: 22925079] - Pallavur V Sivakumar, Richard Garcia, Kimberly S Waggie, Monica Anderson-Haley, Andrew Nelson, Steven D Hughes. Comparison of vascular leak syndrome in mice treated with IL21 or IL2.
Comparative medicine.
2013 Feb; 63(1):13-21. doi:
NULL. [PMID: 23561933] - Hatice Yorulmaz, Fatma Burcu Seker, Göksel Demir, Ibrahim Ertuğrul Yalçın, Baria Oztaş. The effects of zinc treatment on the blood-brain barrier permeability and brain element levels during convulsions.
Biological trace element research.
2013 Feb; 151(2):256-62. doi:
10.1007/s12011-012-9546-y. [PMID: 23179348] - Lola Fenghuei Yen, Vivi Chiali Wei, Eva Yuhua Kuo, Ted Weita Lai. Distinct patterns of cerebral extravasation by Evans blue and sodium fluorescein in rats.
PloS one.
2013; 8(7):e68595. doi:
10.1371/journal.pone.0068595. [PMID: 23861924] - Elizabeth M Chislock, Ann Marie Pendergast. Abl family kinases regulate endothelial barrier function in vitro and in mice.
PloS one.
2013; 8(12):e85231. doi:
10.1371/journal.pone.0085231. [PMID: 24367707] - Vanessa R S Foletto, Maria A Martins, Carlos R Tonussi. The involvement of potassium channels in the peripheral antiedematogenic effect of intrathecally injected morphine in rats.
Anesthesia and analgesia.
2013 Jan; 116(1):232-8. doi:
10.1213/ane.0b013e31826f5cc5. [PMID: 23223096] - Dan Yang, Kai-Bin Tan, Yun-Hua Gao, Hong Liu, Wei-Xiao Yang. Effects of diagnostic ultrasound-targeted microbubble destruction on permeability of normal liver in rats.
Ultrasonics.
2012 Dec; 52(8):1065-71. doi:
10.1016/j.ultras.2012.09.002. [PMID: 23021237] - Parvin Begum, Bunshi Fugetsu. Phytotoxicity of multi-walled carbon nanotubes on red spinach (Amaranthus tricolor L) and the role of ascorbic acid as an antioxidant.
Journal of hazardous materials.
2012 Dec; 243(?):212-22. doi:
10.1016/j.jhazmat.2012.10.025. [PMID: 23146354] - Annette von Drygalski, Christian Furlan-Freguia, Laurent O Mosnier, Subramanian Yegneswaran, Wolfram Ruf, John H Griffin. Infrared fluorescence for vascular barrier breach in vivo--a novel method for quantitation of albumin efflux.
Thrombosis and haemostasis.
2012 Nov; 108(5):981-91. doi:
10.1160/th12-03-0196. [PMID: 23052565] - Tatsuya Oka, Janet Kalesnikoff, Philipp Starkl, Mindy Tsai, Stephen J Galli. Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice.
Laboratory investigation; a journal of technical methods and pathology.
2012 Oct; 92(10):1472-82. doi:
10.1038/labinvest.2012.116. [PMID: 22906983] - Jun Xiang, Rui Lan, Yu-Ping Tang, Yi-Ping Chen, Ding-Fang Cai. Apocynum venetum leaf extract attenuates disruption of the blood-brain barrier and upregulation of matrix metalloproteinase-9/-2 in a rat model of cerebral ischemia-reperfusion injury.
Neurochemical research.
2012 Aug; 37(8):1820-8. doi:
10.1007/s11064-012-0796-z. [PMID: 22592643] - Shoko Morita, Seiji Miyata. Different vascular permeability between the sensory and secretory circumventricular organs of adult mouse brain.
Cell and tissue research.
2012 Aug; 349(2):589-603. doi:
10.1007/s00441-012-1421-9. [PMID: 22584508] - David Fernández-López, Joel Faustino, Richard Daneman, Lu Zhou, Sarah Y Lee, Nikita Derugin, Michael F Wendland, Zinaida S Vexler. Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2012 Jul; 32(28):9588-600. doi:
10.1523/jneurosci.5977-11.2012. [PMID: 22787045] - Chin-Hsien Chang, Kuo-Ti Chen, Chang-Jer Wu, Shih-Liang Chang, Ya-Huang Chiu, Pei-Hsiu Hung, Jih-Chao Yeh, Yen-Lin Chang. Laser-induced carotid artery injury model in the rat for therapeutic agent screening.
Lasers in medical science.
2012 May; 27(3):593-8. doi:
10.1007/s10103-011-0960-8. [PMID: 21953118] - Yuan Zhou, Xiao Yan Xu, Li Qian Chen, Jian Li Yang, Shao Jian Zheng. Nitric oxide exacerbates Al-induced inhibition of root elongation in rice bean by affecting cell wall and plasma membrane properties.
Phytochemistry.
2012 Apr; 76(?):46-51. doi:
10.1016/j.phytochem.2011.12.004. [PMID: 22230427] - Beibei Zhang, Aili Cao, Jiyan Zhou, Zhibi Hu, Dazheng Wu. Effect of jatrorrhizine on delayed gastrointestinal transit in rat postoperative ileus.
The Journal of pharmacy and pharmacology.
2012 Mar; 64(3):413-9. doi:
10.1111/j.2042-7158.2011.01407.x. [PMID: 22309273] - Dezheng Gong, Chengyan Geng, Liping Jiang, Lihui Wang, Hiroyuki Yoshimura, Laifu Zhong. Mechanisms of olive leaf extract-ameliorated rat arthritis caused by kaolin and carrageenan.
Phytotherapy research : PTR.
2012 Mar; 26(3):397-402. doi:
10.1002/ptr.3567. [PMID: 21796704] - Wei Cao, Jing-Hua Li, Da-Yun Feng, Yi Wan, Yu-Feng Liu, Qing-Feng Yang, Jian-Wei Cheng, Si-Yuan Zhao, Hong-Xin Zhang. Effect of transarterial pulsed perfusion with heated saline on tumor vascular permeability in a rabbit VX2 liver tumor model.
European journal of radiology.
2012 Mar; 81(3):e209-16. doi:
10.1016/j.ejrad.2011.01.108. [PMID: 21345630] - C H J Pinheiro, K F Vitzel, R Curi. Effect of N-acetylcysteine on markers of skeletal muscle injury after fatiguing contractile activity.
Scandinavian journal of medicine & science in sports.
2012 Feb; 22(1):24-33. doi:
10.1111/j.1600-0838.2010.01143.x. [PMID: 20673252] - Camilla Betti, Chiara Lico, Dario Maffi, Simone D'Angeli, Maria Maddalena Altamura, Eugenio Benvenuto, Franco Faoro, Selene Baschieri. Potato virus X movement in Nicotiana benthamiana: new details revealed by chimeric coat protein variants.
Molecular plant pathology.
2012 Feb; 13(2):198-203. doi:
10.1111/j.1364-3703.2011.00739.x. [PMID: 21851552] - Dan Zhou, Yi Guo, Yong-Ming Guo, Sai Zhang, Ping Pan. Distribution and permeability of capillaries at the skin of the conception vessel and the governor vessel in healthy rabbits.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2011 Dec; 31(4):356-9. doi:
10.1016/s0254-6272(12)60018-1. [PMID: 22462245] - Bahriye Sirav, Nesrin Seyhan. Effects of radiofrequency radiation exposure on blood-brain barrier permeability in male and female rats.
Electromagnetic biology and medicine.
2011 Dec; 30(4):253-60. doi:
10.3109/15368378.2011.600167. [PMID: 22047463] - Jü-qin Huang, Qing-luan Lv, Huai You Wang. Spectroscopic study of the competitive interaction between streptomycin and Evans blue to bovine serum albumin.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2011 Dec; 83(1):28-33. doi:
10.1016/j.saa.2011.05.027. [PMID: 21937264] - C Langdon Fielding, K Gary Magdesian, Judy E Edman. Determination of body water compartments in neonatal foals by use of indicator dilution techniques and multifrequency bioelectrical impedance analysis.
American journal of veterinary research.
2011 Oct; 72(10):1390-6. doi:
10.2460/ajvr.72.10.1390. [PMID: 21962283] - Shih-Chieh Chen, Chun-Chih Liu, Shin-Yin Huang, Shean-Jaw Chiou. Vascular hyperpermeability in response to inflammatory mustard oil is mediated by Rho kinase in mice systemically exposed to arsenic.
Microvascular research.
2011 Sep; 82(2):182-9. doi:
10.1016/j.mvr.2011.06.001. [PMID: 21703283] - Shailendra Joshi, Aysegul Ergin, Mei Wang, Roberto Reif, Jane Zhang, Jeffrey N Bruce, Irving J Bigio. Inconsistent blood brain barrier disruption by intraarterial mannitol in rabbits: implications for chemotherapy.
Journal of neuro-oncology.
2011 Aug; 104(1):11-9. doi:
10.1007/s11060-010-0466-4. [PMID: 21153681] - Shinji Kobuchi, Keizo Fukushima, Masakazu Shibata, Yukako Ito, Nobuyuki Sugioka, Kanji Takada. Pharmacokinetics of clomipramine, an antidepressant, in poloxamer 407-induced hyperlipidaemic model rats.
The Journal of pharmacy and pharmacology.
2011 Apr; 63(4):515-23. doi:
10.1111/j.2042-7158.2010.01245.x. [PMID: 21401603] - Alexander N Garcia, Stephen M Vogel, Yulia A Komarova, Asrar B Malik. Permeability of endothelial barrier: cell culture and in vivo models.
Methods in molecular biology (Clifton, N.J.).
2011; 763(?):333-54. doi:
10.1007/978-1-61779-191-8_23. [PMID: 21874463] - Mehmet Kaya, Bulent Ahishali. Assessment of permeability in barrier type of endothelium in brain using tracers: Evans blue, sodium fluorescein, and horseradish peroxidase.
Methods in molecular biology (Clifton, N.J.).
2011; 763(?):369-82. doi:
10.1007/978-1-61779-191-8_25. [PMID: 21874465] - Brent M Bany, G Scot Hamilton. Assessment of permeability barriers to macromolecules in the rodent endometrium at the onset of implantation.
Methods in molecular biology (Clifton, N.J.).
2011; 763(?):83-94. doi:
10.1007/978-1-61779-191-8_5. [PMID: 21874445]