Acetylphenylalanyl-prolyl-boroarginine (BioDeep_00000843826)
代谢物信息卡片
化学式: C21H33BN6O5 (460.2605358)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: B(C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=CC=C2)NC(=O)C)(O)O
InChI: InChI=1S/C21H33BN6O5/c1-14(29)26-16(13-15-7-3-2-4-8-15)20(31)28-12-6-9-17(28)19(30)27-18(22(32)33)10-5-11-25-21(23)24/h2-4,7-8,16-18,32-33H,5-6,9-13H2,1H3,(H,26,29)(H,27,30)(H4,23,24,25)/t16-,17+,18+/m1/s1
描述信息
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents
D050299 - Fibrin Modulating Agents
D002317 - Cardiovascular Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- P C Wong, E J Crain, R M Knabb, R P Meade, M L Quan, C A Watson, R R Wexler, M R Wright, A M Slee. Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis.
The Journal of pharmacology and experimental therapeutics.
2000 Oct; 295(1):212-8. doi:
NULL. [PMID: 10991981] - A Rupin, P Mennecier, C Lila, G de Nanteuil, T J Verbeuren. Selection of S18326 as a new potent and selective boronic acid direct thrombin inhibitor.
Thrombosis and haemostasis.
1997 Oct; 78(4):1221-7. doi:
10.1055/s-0038-1657718. [PMID: 9364988] - T J Mitchell, R M Knabb, D D Christ, A R Farmer, T M Reilly. Analysis of the thrombin inhibitor DuP 714 by an enzyme-linked immunosorbent assay.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
1994 Aug; 5(4):517-21. doi:
NULL. [PMID: 7841307] - K E Achyuthan, M A Santiago, C S Greenberg. A microtiter plate assay for factor XIII A-chain-fibrin interactions.
Analytical biochemistry.
1994 May; 219(1):43-8. doi:
10.1006/abio.1994.1229. [PMID: 8059954] - B Kaiser, D Callas, D Hoppensteadt, K Mallinowska, J Fareed. Comparative studies on the inhibitory spectrum of recombinant hirudin, DuP 714 and heparin on thrombin and factor Xa generation in biochemically defined systems.
Thrombosis research.
1994 Mar; 73(5):327-35. doi:
10.1016/0049-3848(94)90028-0. [PMID: 8016817] - P N Chomiak, J M Walenga, M J Koza, T M Reilly, P Turlapathy, R Pifarre. Investigation of a thrombin inhibitor peptide as an alternative to heparin in cardiopulmonary bypass surgery.
Circulation.
1993 Nov; 88(5 Pt 2):II407-12. doi:
NULL. [PMID: 7993389] - A T Chiu, S A Mousa, L J Pease, W A Roscoe, J M Bozarth, T M Reilly, R D Smith, P B Timmermans. Inhibition of the thrombin-platelet reactions by DuP 714.
Biochemical and biophysical research communications.
1991 Sep; 179(3):1500-8. doi:
10.1016/0006-291x(91)91742-u. [PMID: 1930190] - M A Hussain, R Knabb, B J Aungst, C Kettner. Anticoagulant activity of a peptide boronic acid thrombin inhibitor by various routes of administration in rats.
Peptides.
1991 Sep; 12(5):1153-4. doi:
10.1016/0196-9781(91)90073-x. [PMID: 1800952] - C Kettner, L Mersinger, R Knabb. The selective inhibition of thrombin by peptides of boroarginine.
The Journal of biological chemistry.
1990 Oct; 265(30):18289-97. doi:
10.1016/s0021-9258(17)44751-x. [PMID: 2211702]