Epidepride (BioDeep_00000843767)
代谢物信息卡片
Epidepride
化学式: C16H23IN2O3 (418.07533579999995)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN1CCCC1CNC(=O)C2=C(C(=CC(=C2)I)OC)OC
InChI: InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lars H Pinborg, Charlotte Videbaek, Morten Ziebell, Torben Mackeprang, Lars Friberg, Hans Rasmussen, Gitte M Knudsen, Birte Y Glenthoj. [123I]epidepride binding to cerebellar dopamine D2/D3 receptors is displaceable: implications for the use of cerebellum as a reference region.
NeuroImage.
2007 Feb; 34(4):1450-3. doi:
10.1016/j.neuroimage.2006.11.003. [PMID: 17175177] - Marleen Kars, Ferdinand Roelfsema, Johannes A Romijn, Alberto M Pereira. Malignant prolactinoma: case report and review of the literature.
European journal of endocrinology.
2006 Oct; 155(4):523-34. doi:
10.1530/eje.1.02268. [PMID: 16990651] - G M Knudsen, M Karlsborg, G Thomsen, K Krabbe, L Regeur, T Nygaard, C Videbaek, L Werdelin. Imaging of dopamine transporters and D2 receptors in patients with Parkinson's disease and multiple system atrophy.
European journal of nuclear medicine and molecular imaging.
2004 Dec; 31(12):1631-8. doi:
10.1007/s00259-004-1578-x. [PMID: 15583914] - E Tupala, H Hall, K Bergström, T Särkioja, P Räsänen, T Mantere, J Callaway, J Hiltunen, J Tiihonen. Dopamine D(2)/D(3)-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics.
Molecular psychiatry.
2001 May; 6(3):261-7. doi:
10.1038/sj.mp.4000859. [PMID: 11326293] - A Varrone, M Fujita, N P Verhoeff, S S Zoghbi, R M Baldwin, N Rajeevan, D S Charney, J P Seibyl, R B Innis. Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2000 Aug; 41(8):1343-51. doi:
NULL. [PMID: 10945525] - L H Pinborg, C Videbaek, G M Knudsen, C G Swahn, C Halldin, L Friberg, O B Paulson, N A Lassen. Dopamine D(2) receptor quantification in extrastriatal brain regions using [(123)I]epidepride with bolus/infusion.
Synapse (New York, N.Y.).
2000 Jun; 36(4):322-9. doi:
10.1002/(sici)1098-2396(20000615)36:4<322::aid-syn9>3.0.co;2-w. [PMID: 10819910] - D S Kim, M S Szczypka, R D Palmiter. Dopamine-deficient mice are hypersensitive to dopamine receptor agonists.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2000 Jun; 20(12):4405-13. doi:
10.1523/jneurosci.20-12-04405.2000. [PMID: 10844009] - K A Bergström, M Yu, J T Kuikka, K K Akerman, J Hiltunen, J Lehtonen, C Halldin, J Tiihonen. Metabolism of [123I]epidepride may affect brain dopamine D2 receptor imaging with single-photon emission tomography.
European journal of nuclear medicine.
2000 Feb; 27(2):206-8. doi:
10.1007/s002590050028. [PMID: 10755727] - E Repo, J T Kuikka, K A Bergström, J Karhu, J Hiltunen, J Tiihonen. Dopamine transporter and D2-receptor density in late-onset alcoholism.
Psychopharmacology.
1999 Dec; 147(3):314-8. doi:
10.1007/s002130051173. [PMID: 10639691] - M Ichise, M Fujita, J P Seibyl, N P Verhoeff, R M Baldwin, S S Zoghbi, N Rajeevan, D S Charney, R B Innis. Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1999 Nov; 40(11):1902-12. doi:
NULL. [PMID: 10565788] - O Langer, C Halldin, F Dollé, C G Swahn, H Olsson, P Karlsson, H Hall, J Sandell, C Lundkvist, F Vaufrey, C Loc'h, C Crouzel, B Mazière, L Farde. Carbon-11 epidepride: a suitable radioligand for PET investigation of striatal and extrastriatal dopamine D2 receptors.
Nuclear medicine and biology.
1999 Jul; 26(5):509-18. doi:
10.1016/s0969-8051(99)00005-0. [PMID: 10473189] - M Naumann, W Pirker, K Reiners, K W Lange, G Becker, T Brücke. Imaging the pre- and postsynaptic side of striatal dopaminergic synapses in idiopathic cervical dystonia: a SPECT study using [123I] epidepride and [123I] beta-CIT.
Movement disorders : official journal of the Movement Disorder Society.
1998 Mar; 13(2):319-23. doi:
10.1002/mds.870130219. [PMID: 9539347] - W Pirker, S Asenbaum, S Wenger, J Kornhuber, P Angelberger, L Deecke, I Podreka, T Brücke. Iodine-123-epidepride-SPECT: studies in Parkinson's disease, multiple system atrophy and Huntington's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1997 Nov; 38(11):1711-7. doi:
NULL. [PMID: 9374338] - J R Votaw, M S Ansari, N S Mason, D Schmidt, T de Paulis, G Holburn, J A Clanton, D B Votaw, R G Manning, R M Kessler. Dosimetry of iodine-123-epidepride: a dopamine D2 receptor ligand.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1995 Jul; 36(7):1316-21. doi:
". [PMID: 7790962] - R M Baldwin, Y Zea-Ponce, S S Zoghbi, M S al-Tikriti, J P Seibyl, E H Sybirska, R T Malison, M Laruelle, D S Charney, P B Hoffer. Pharmacokinetics of the three radioiodinated dopamine D2 receptor ligands [123I]IBF, [123I]epidepride and [123I]2'-ISP in nonhuman primates.
Nuclear medicine and biology.
1994 Oct; 21(7):969-76. doi:
10.1016/0969-8051(94)90087-6. [PMID: 9234352] - D E Womer, B C Jones, V G Erwin. Characterization of dopamine transporter and locomotor effects of cocaine, GBR 12909, epidepride, and SCH 23390 in C57BL and DBA mice.
Pharmacology, biochemistry, and behavior.
1994 Jun; 48(2):327-35. doi:
10.1016/0091-3057(94)90534-7. [PMID: 8090798] - R M Kessler, J R Votaw, T de Paulis, D R Bingham, M S Ansari, N S Mason, G Holburn, D E Schmidt, D B Votaw, R G Manning. Evaluation of 5-[18F]fluoropropylepidepride as a potential PET radioligand for imaging dopamine D2 receptors.
Synapse (New York, N.Y.).
1993 Nov; 15(3):169-76. doi:
10.1002/syn.890150302. [PMID: 8278895] - V G Erwin, D E Womer, A D Campbell, B C Jones. Pharmacogenetics of cocaine: II. Mesocorticolimbic and striatal dopamine and cocaine receptors in C57BL and DBA mice.
Pharmacogenetics.
1993 Aug; 3(4):189-96. doi:
10.1097/00008571-199308000-00003. [PMID: 8220438]