Taxane (BioDeep_00000843731)

   


代谢物信息卡片


Taxane

化学式: C20H36 (276.2816856)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CCCC2(C1CC3CCC(C(C3(C)C)CC2)C)C
InChI: InChI=1S/C20H36/c1-14-7-6-11-20(5)12-10-17-15(2)8-9-16(13-18(14)20)19(17,3)4/h14-18H,6-13H2,1-5H3/t14-,15-,16+,17+,18-,20+/m1/s1

描述信息

D000970 - Antineoplastic Agents

同义名列表

1 个代谢物同义名

Taxane



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Nicole Yeung, Tiffany Li, Hui-Ming Lin, Hannah C Timmins, David Goldstein, Michelle Harrison, Michael Friedlander, Kate L Mahon, Corey Giles, Peter J Meikle, Susanna B Park, Lisa G Horvath. Plasma Lipidomic Profiling Identifies Elevated Triglycerides as Potential Risk Factor in Chemotherapy-Induced Peripheral Neuropathy. JCO precision oncology. 2024 Apr; 8(?):e2300690. doi: 10.1200/po.23.00690. [PMID: 38691814]
  • Zhenlu Xu, Yaohua Zhai, Huimin Chang, Da Yan, Pengliang Ge, Guangming Ren, Lijun Zhang, Ye Yuan, Ruoyan Wang, Wentao Li, Fuguang Li, Maozhi Ren, Huijuan Mo. Heterologous expression of taxane genes confers resistance to fall armyworm in Nicotiana benthamiana. Plant cell reports. 2024 Mar; 43(4):94. doi: 10.1007/s00299-024-03169-z. [PMID: 38472660]
  • Fan Luo, Donggui Wan, Jun Liu, Dongmei Chen, Mengqi Yuan, Chenyang Zhang, Qing Liu. Efficacy of the traditional Chinese medicine, Buyang Huanwu Decoction, at preventing taxane-induced peripheral neuropathy in breast cancer patients: A prospective, randomized, controlled study. Medicine. 2024 Mar; 103(9):e37338. doi: 10.1097/md.0000000000037338. [PMID: 38428887]
  • Bin Jiang, Lei Gao, Haijun Wang, Yaping Sun, Xiaolin Zhang, Han Ke, Shengchao Liu, Pengchen Ma, Qinggang Liao, Yue Wang, Huan Wang, Yugeng Liu, Ran Du, Torben Rogge, Wei Li, Yi Shang, K N Houk, Xingyao Xiong, Daoxin Xie, Sanwen Huang, Xiaoguang Lei, Jianbin Yan. Characterization and heterologous reconstitution of Taxus biosynthetic enzymes leading to baccatin III. Science (New York, N.Y.). 2024 Jan; ?(?):eadj3484. doi: 10.1126/science.adj3484. [PMID: 38271490]
  • Edgar Perez-Matas, Diego Hidalgo-Martinez, Elisabeth Moyano, Javier Palazon, Mercedes Bonfill. Overexpression of BAPT and DBTNBT genes in Taxus baccata in vitro cultures to enhance the biotechnological production of paclitaxel. Plant biotechnology journal. 2023 Sep; ?(?):. doi: 10.1111/pbi.14182. [PMID: 37772738]
  • Xiaodan Wu, Ying Wang, Bingyang Qin, Guansong Shao, Zihan Wang, Tao Wang, Yujie Fu. A nanocellulose molecularly imprinted membrane: Preparation, characterization and application in targeted separation of taxane 10-deacetylbaccatin III. International journal of biological macromolecules. 2023 Sep; ?(?):126794. doi: 10.1016/j.ijbiomac.2023.126794. [PMID: 37699463]
  • Ainoa Escrich, Diego Hidalgo, Mercedes Bonfill, Javier Palazon, Raul Sanchez-Muñoz, Elisabeth Moyano. Polyploidy as a strategy to increase taxane production in yew cell cultures: Obtaining and characterizing a Taxus baccata tetraploid cell line. Plant science : an international journal of experimental plant biology. 2023 Sep; 334(?):111776. doi: 10.1016/j.plantsci.2023.111776. [PMID: 37343603]
  • Dmitry V Kochkin, Elena V Demidova, Elena B Globa, Alexander M Nosov. Profiling of Taxoid Compounds in Plant Cell Cultures of Different Species of Yew (Taxus spp.). Molecules (Basel, Switzerland). 2023 Feb; 28(5):. doi: 10.3390/molecules28052178. [PMID: 36903424]
  • Andrew Hillowe, Chris Gordon, Liqun Wang, Robert C Rizzo, Lloyd C Trotman, Iwao Ojima, Agnieszka Bialkowska, Martin Kaczocha. Fatty acid binding protein 5 regulates docetaxel sensitivity in taxane-resistant prostate cancer cells. PloS one. 2023; 18(10):e0292483. doi: 10.1371/journal.pone.0292483. [PMID: 37796964]
  • Mahsa Bamneshin, Mohammad Hossein Mirjalili, Mohammad Reza Naghavi, Rosa M Cusido, Javier Palazón. Gene expression pattern and taxane biosynthesis in a cell suspension culture of Taxus baccata L. subjected to light and a phenylalanine ammonia lyase (PAL) inhibitor. Journal of photochemistry and photobiology. B, Biology. 2022 Sep; 234(?):112532. doi: 10.1016/j.jphotobiol.2022.112532. [PMID: 35908357]
  • Diya Hasan, Yazan Ismail, Ahmad Al Tibi, Safaa A Al-Zeidaneen, Mohanad Odeh, George J Burghel, Iyad Natsheh, Amid Abdelnour. Serum Biomarkers for Chemotherapy Cardiotoxicity Risk Detection of Breast Cancer Patients. Asian Pacific journal of cancer prevention : APJCP. 2021 10; 22(10):3355-3363. doi: 10.31557/apjcp.2021.22.10.3355. [PMID: 34711013]
  • Heidi Fettke, Edmond M Kwan, Patricia Bukczynska, Jason A Steen, Maria Docanto, Nicole Ng, Phillip Parente, Andrew Mant, Siavash Foroughi, Carmel Pezaro, Christine Hauser, Tu Nguyen-Dumont, Melissa C Southey, Arun A Azad. Independent prognostic impact of plasma NCOA2 alterations in metastatic castration-resistant prostate cancer. The Prostate. 2021 09; 81(13):992-1001. doi: 10.1002/pros.24194. [PMID: 34254334]
  • Laura Raquel Comini, Roxana Valeria Alasino, Victoria Leonhard, Karina Lilian Bierbrauer, Dante Miguel Beltramo. Self-assembled micelles of the (lipo) glycopeptides, teicoplanin, as taxane nanocarriers. Nanotechnology. 2021 Aug; 32(46):. doi: 10.1088/1361-6528/ac1979. [PMID: 34330111]
  • Ju Won Kim, Soohyeon Lee, Hye Sook Kim, Yoon Ji Choi, Jinho Yoo, Keon Uk Park, Seok Yun Kang, Yeon Hee Park, Kyung Hae Jung, Jin-Hee Ahn, Ho-Suk Oh, In Sil Choi, Hee Jun Kim, Kyung-Hun Lee, Suee Lee, Jae Hong Seo, In Hae Park, Kyung Eun Lee, Ho Young Kim, Kyong Hwa Park. Prognostic effects of cytokine levels on patients treated with taxane and zoledronic acid for metastatic breast cancer in bone (BEAT-ZO) (KCSG BR 10-13). Cytokine. 2021 06; 142(?):155487. doi: 10.1016/j.cyto.2021.155487. [PMID: 33770643]
  • Tao Wang, Lingyu Li, Weibing Zhuang, Fengjiao Zhang, Xiaochun Shu, Ning Wang, Zhong Wang. Recent Research Progress in Taxol Biosynthetic Pathway and Acylation Reactions Mediated by Taxus Acyltransferases. Molecules (Basel, Switzerland). 2021 May; 26(10):. doi: 10.3390/molecules26102855. [PMID: 34065782]
  • Hapidah Hapidah, Yulia Yusrini Djabir, Prihantono Prihantono. Increased aldehyde dehydrogenase 1 (ALDH1) levels are associated with chemo-responsiveness in breast cancer patients treated with taxane-adriamycin-cyclophosphamide regimen. Breast disease. 2021; 40(S1):S33-S37. doi: 10.3233/bd-219005. [PMID: 34057116]
  • Raul Sanchez-Muï Oz, Lorena Almagro, Rosa M Cusido, Mercedes Bonfill, Javier Palazon, Elisabeth Moyano. Transfecting Taxus � media Protoplasts to Study Transcription Factors BIS2 and TSAR2 as Activators of Taxane-Related Genes. Plant & cell physiology. 2020 Mar; 61(3):576-583. doi: 10.1093/pcp/pcz225. [PMID: 31841159]
  • Chiara Pizzamiglio, Paolo Ripellino, Paolo Prandi, Nausicaa Clemente, Chiara Saggia, Valentina Rossi, Gionata Strigaro, Pier Luigi Foglio Bonda, Cristoforo Comi, Roberto Cantello. Nerve conduction, circulating osteopontin and taxane-induced neuropathy in breast cancer patients. Neurophysiologie clinique = Clinical neurophysiology. 2020 Feb; 50(1):47-54. doi: 10.1016/j.neucli.2019.12.001. [PMID: 31928832]
  • Kang Chen, Xiao-Qin Liu, Wen-Li Wang, Jian-Guang Luo, Ling-Yi Kong. Taxumarienes A-G, seven new α-glucosidase inhibitory taxane-diterpenoids from the leaves of Taxus mairei. Bioorganic chemistry. 2020 01; 94(?):103400. doi: 10.1016/j.bioorg.2019.103400. [PMID: 31699390]
  • Channing J Paller, Danilo Piana, James R Eshleman, Stacy Riel, Samuel R Denmeade, Pedro Isaacsson Velho, Steven P Rowe, Martin G Pomper, Emmanuel S Antonarakis, Jun Luo, Mario A Eisenberger. A pilot study of prostate-specific membrane antigen (PSMA) dynamics in men undergoing treatment for advanced prostate cancer. The Prostate. 2019 10; 79(14):1597-1603. doi: 10.1002/pros.23883. [PMID: 31361358]
  • Zhaohua Richard Huang, Suresh Kumar Tipparaju, Dmitri B Kirpotin, Christine Pien, Tad Kornaga, Charles O Noble, Alexander Koshkaryev, Jimmy Tran, Walid S Kamoun, Daryl C Drummond. Formulation optimization of an ephrin A2 targeted immunoliposome encapsulating reversibly modified taxane prodrugs. Journal of controlled release : official journal of the Controlled Release Society. 2019 09; 310(?):47-57. doi: 10.1016/j.jconrel.2019.08.006. [PMID: 31400383]
  • Rafael J A Cámara, Lukas Schwentner, Thomas W P Friedl, Miriam Deniz, Visnja Fink, Krisztian Lato, Peter Widschwendter, Brigitte Rack, Wolfgang Janni, Susanne Singer, Inga Bekes. Quality of life during and after adjuvant anthracycline-taxane-based chemotherapy with or without Gemcitabine in high-risk early breast cancer: results of the SUCCESS A trial. Breast cancer research and treatment. 2019 Jun; 175(3):627-635. doi: 10.1007/s10549-019-05171-6. [PMID: 30900137]
  • Allison Gartung, Jun Yang, Vikas P Sukhatme, Diane R Bielenberg, Djanira Fernandes, Jaimie Chang, Birgitta A Schmidt, Sung Hee Hwang, David Zurakowski, Sui Huang, Mark W Kieran, Bruce D Hammock, Dipak Panigrahy. Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 2019 01; 116(5):1698-1703. doi: 10.1073/pnas.1803999116. [PMID: 30647111]
  • Madoka Koyanagi, Satoshi Imai, Takayuki Nakagawa, Kazuo Matsubara. [Identification of biomarkers and new therapies for taxane-induced peripheral neuropathy]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2019; 154(5):241-244. doi: 10.1254/fpj.154.241. [PMID: 31735751]
  • Gennaro Riccio, Eduardo Sommella, Nadia Badolati, Emanuela Salviati, Sara Bottone, Pietro Campiglia, Monica Dentice, Gian Carlo Tenore, Mariano Stornaiuolo, Ettore Novellino. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation. Nutrients. 2018 Nov; 10(11):. doi: 10.3390/nu10111808. [PMID: 30463345]
  • Marziyeh Sarmadi, Naser Karimi, Javier Palazón, Alireza Ghassempour, Mohammad Hossein Mirjalili. The effects of salicylic acid and glucose on biochemical traits and taxane production in a Taxus baccata callus culture. Plant physiology and biochemistry : PPB. 2018 Nov; 132(?):271-280. doi: 10.1016/j.plaphy.2018.09.013. [PMID: 30240989]
  • Raul Sanchez-Muñoz, Mercedes Bonfill, Rosa M Cusidó, Javier Palazón, Elisabeth Moyano. Advances in the Regulation of In Vitro Paclitaxel Production: Methylation of a Y-Patch Promoter Region Alters BAPT Gene Expression in Taxus Cell Cultures. Plant & cell physiology. 2018 Nov; 59(11):2255-2267. doi: 10.1093/pcp/pcy149. [PMID: 30060238]
  • Samavia Mubeen, Zhi-Liang Li, Qiao-Ming Huang, Chun-Tao He, Zhong-Yi Yang. Comparative Transcriptome Analysis Revealed the Tissue-Specific Accumulations of Taxanes among Three Experimental Lines of Taxus yunnanensis. Journal of agricultural and food chemistry. 2018 Oct; 66(40):10410-10420. doi: 10.1021/acs.jafc.8b03502. [PMID: 30208705]
  • Terence Ng, Xiang Yun Phey, Hui Ling Yeo, Maung Shwe, Yan Xiang Gan, Raymond Ng, Han Kiat Ho, Alexandre Chan. Impact of Adjuvant Anthracycline-Based and Taxane-Based Chemotherapy on Plasma VEGF Levels and Cognitive Function in Breast Cancer Patients: A Longitudinal Study. Clinical breast cancer. 2018 10; 18(5):e927-e937. doi: 10.1016/j.clbc.2018.03.016. [PMID: 29705024]
  • Yukie Fujimoto, Tomoko Higuchi, Arisa Nishimukai, Yoshimasa Miyagawa, Ayako Kira, Hiromi Ozawa, Ayako Bun, Michiko Imamura, Yasuo Miyoshi. High levels of serum CA15-3 and residual invasive tumor size are associated with poor prognosis for breast cancer patients with non-pathological complete response after neoadjuvant chemotherapy. Journal of surgical oncology. 2018 Jul; 118(1):228-237. doi: 10.1002/jso.25125. [PMID: 29936704]
  • Jung-Woo Chae, Peh Siang Chua, Terence Ng, Angie Hui Ling Yeo, Maung Shwe, Yan Xiang Gan, Sreemanee Dorajoo, Koon Mian Foo, Kiley Wei-Jen Loh, Si-Lin Koo, Wen Yee Chay, Tira Jing Ying Tan, Sok Yuen Beh, Elaine Hsuen Lim, Guek Eng Lee, Rebecca Dent, Yoon Sim Yap, Raymond Ng, Han Kiat Ho, Alexandre Chan. Association of mitochondrial DNA content in peripheral blood with cancer-related fatigue and chemotherapy-related cognitive impairment in early-stage breast cancer patients: a prospective cohort study. Breast cancer research and treatment. 2018 Apr; 168(3):713-721. doi: 10.1007/s10549-017-4640-7. [PMID: 29313215]
  • Roser Velasco, Xavier Navarro, Miguel Gil-Gil, Mireia Herrando-Grabulosa, Aina Calls, Jordi Bruna. Neuropathic Pain and Nerve Growth Factor in Chemotherapy-Induced Peripheral Neuropathy: Prospective Clinical-Pathological Study. Journal of pain and symptom management. 2017 12; 54(6):815-825. doi: 10.1016/j.jpainsymman.2017.04.021. [PMID: 28797868]
  • Elisabeth Trapp, J Steidl, B Rack, M S Kupka, U Andergassen, J Jückstock, A Kurt, T Vilsmaier, A de Gregorio, N de Gregorio, M Tzschaschel, C Lato, A Polasik, H Tesch, A Schneeweiss, M W Beckmann, P A Fasching, W Janni, V Müller. Anti-Müllerian hormone (AMH) levels in premenopausal breast cancer patients treated with taxane-based adjuvant chemotherapy - A translational research project of the SUCCESS A study. Breast (Edinburgh, Scotland). 2017 Oct; 35(?):130-135. doi: 10.1016/j.breast.2017.07.007. [PMID: 28732324]
  • Winnie Yeo, Frankie K F Mo, Elizabeth Pang, Joyce J S Suen, Jane Koh, Herbert H F Loong, Christopher C H Yip, Rita Y W Ng, Claudia H W Yip, Nelson L S Tang, Giok S Liem. Profiles of lipids, blood pressure and weight changes among premenopausal Chinese breast cancer patients after adjuvant chemotherapy. BMC women's health. 2017 07; 17(1):55. doi: 10.1186/s12905-017-0409-8. [PMID: 28750616]
  • Phu Hoang Dang, Hai Xuan Nguyen, Truc Thanh Thi Duong, Thao Kim Thi Tran, Phuc Thi Nguyen, Trang Kieu Thi Vu, Hung Chi Vuong, Nguyen Huu Trong Phan, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Suresh Awale. α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana. Journal of natural products. 2017 04; 80(4):1087-1095. doi: 10.1021/acs.jnatprod.7b00006. [PMID: 28240909]
  • Junfei Tao, Rongwei Yan, Leilei Zhao, Dongmei Wang, Xinjun Xu. Separation and purification of two taxanes and one xylosyl-containing taxane from Taxus wallichiana Zucc.: A comparison between high-speed countercurrent chromatography and reversed-phase flash chromatography. Journal of separation science. 2017 Mar; 40(6):1273-1282. doi: 10.1002/jssc.201601066. [PMID: 28106330]
  • Charlotte S Lo, Sanaz Sanii, David R Kroeger, Katy Milne, Aline Talhouk, Derek S Chiu, Kurosh Rahimi, Patricia A Shaw, Blaise A Clarke, Brad H Nelson. Neoadjuvant Chemotherapy of Ovarian Cancer Results in Three Patterns of Tumor-Infiltrating Lymphocyte Response with Distinct Implications for Immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Feb; 23(4):925-934. doi: 10.1158/1078-0432.ccr-16-1433. [PMID: 27601594]
  • Hangxiang Wang, Jianmei Chen, Chang Xu, Linlin Shi, Munire Tayier, Jiahui Zhou, Jun Zhang, Jiaping Wu, Zhijian Ye, Tao Fang, Weidong Han. Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations. Theranostics. 2017; 7(15):3638-3652. doi: 10.7150/thno.20028. [PMID: 29109766]
  • Yong Wang, Jiaying Wang, Hao Wang, Wencai Ye. Novel taxane derivatives from Taxus wallichiana with high anticancer potency on tumor cells. Chemical biology & drug design. 2016 10; 88(4):556-61. doi: 10.1111/cbdd.12782. [PMID: 27153813]
  • Weiwei Huang, Jian Liu, Fan Wu, Kan Chen, Nani Li, Yi Hong, Cheng Huang, Hongyu Zhen, Lin Lin. The efficacy and safety of endostar combined with taxane-based regimens for HER-2-negative metastatic breast cancer patients. Oncotarget. 2016 May; 7(21):31501-7. doi: 10.18632/oncotarget.8967. [PMID: 27129172]
  • Chunfang Zhao, Guanghao Song, Chunhua Fu, Yanshan Dong, Hang Xu, Hua Zhang, Long Jiang Yu. A systematic approach to expound the variations in taxane production under different dissolved oxygen conditions in Taxus chinensis cells. Plant cell reports. 2016 Mar; 35(3):541-59. doi: 10.1007/s00299-015-1902-x. [PMID: 26620815]
  • Martina Di Modica, Lucia Sfondrini, Viola Regondi, Stefania Varchetta, Barbara Oliviero, Gabriella Mariani, Giulia Valeria Bianchi, Daniele Generali, Andrea Balsari, Tiziana Triulzi, Elda Tagliabue. Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition. Oncotarget. 2016 Jan; 7(1):255-65. doi: 10.18632/oncotarget.6353. [PMID: 26595802]
  • Srinivas Ganta, Amit Singh, Yashesh Rawal, Joseph Cacaccio, Niravkumar R Patel, Praveen Kulkarni, Craig F Ferris, Mansoor M Amiji, Timothy P Coleman. Formulation development of a novel targeted theranostic nanoemulsion of docetaxel to overcome multidrug resistance in ovarian cancer. Drug delivery. 2016; 23(3):968-80. doi: 10.3109/10717544.2014.923068. [PMID: 24901206]
  • A Rasmy, W Abozeed, S Elsamany, M El Baiomy, A Nashwa, A Amrallah, E Hasaan, A Alzahrani, M Faris, K Alsaleh, A AlFaraj. Correlation of Preoperative Ki67 and Serum CA15.3 Levels with Outcome in Early Breast Cancers a Multi Institutional Study. Asian Pacific journal of cancer prevention : APJCP. 2016; 17(7):3595-600. doi: NULL. [PMID: 27510014]
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  • Emily I Chen, Katherine D Crew, Meghna Trivedi, Danielle Awad, Mathew Maurer, Kevin Kalinsky, Antonius Koller, Purvi Patel, Jenny Kim Kim, Dawn L Hershman. Identifying Predictors of Taxane-Induced Peripheral Neuropathy Using Mass Spectrometry-Based Proteomics Technology. PloS one. 2015; 10(12):e0145816. doi: 10.1371/journal.pone.0145816. [PMID: 26710119]
  • Ana-Belén Sabater-Jara, Miriam Onrubia, Elisabeth Moyano, Mercedes Bonfill, Javier Palazón, María A Pedreño, Rosa M Cusidó. Synergistic effect of cyclodextrins and methyl jasmonate on taxane production in Taxus x media cell cultures. Plant biotechnology journal. 2014 Oct; 12(8):1075-84. doi: 10.1111/pbi.12214. [PMID: 24909837]
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