Midafotel (BioDeep_00000843718)
代谢物信息卡片
化学式: C8H15N2O5P (250.0719)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CN(CC(N1)C(=O)O)CC=CP(=O)(O)O
InChI: InChI=1S/C8H15N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h1,5,7,9H,2-4,6H2,(H,11,12)(H2,13,14,15)/b5-1+/t7-/m1/s1
描述信息
D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018691 - Excitatory Amino Acid Antagonists
C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- A A Assi. N6-cyclohexyladenosine and 3-(2-carboxypiperazine-4-yl)-1-propenyl-1-phosphonic acid enhance the effect of antiepileptic drugs against induced seizures in mice.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2001 Jan; 4(1):42-51. doi:
NULL. [PMID: 11302789] - A Bespalov, M Kudryashova, E Zvartau. Prolongation of morphine analgesia by competitive NMDA receptor antagonist D-CPPene (SDZ EAA 494) in rats.
European journal of pharmacology.
1998 Jun; 351(3):299-305. doi:
10.1016/s0014-2999(98)00324-0. [PMID: 9721021] - E N Bum, C L Meier, S Urwyler, Y Wang, P L Herrling. Extracts from rhizomes of Cyperus articulatus (Cyperaceae) displace [3H]CGP39653 and [3H]glycine binding from cortical membranes and selectively inhibit NMDA receptor-mediated neurotransmission.
Journal of ethnopharmacology.
1996 Nov; 54(2-3):103-11. doi:
10.1016/s0378-8741(96)01453-5. [PMID: 8953423] - G De Sarro, S Renne, F Nava, A De Sarro. Fenbufen pretreatment potentiates the anticonvulsant activity of CPPene and NBQX in DBA/2 mice.
The Journal of pharmacy and pharmacology.
1994 Dec; 46(12):1017-22. doi:
10.1111/j.2042-7158.1994.tb03259.x. [PMID: 7714713] - T Zarnowski, Z Kleinrok, W A Turski, S J Czuczwar. The competitive NMDA antagonist, D-CPP-ene, potentiates the anticonvulsant activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.
Neuropharmacology.
1994 May; 33(5):619-24. doi:
10.1016/0028-3908(94)90166-x. [PMID: 7936096] - S Sveinbjornsdottir, J W Sander, D Upton, P J Thompson, P N Patsalos, D Hirt, M Emre, D Lowe, J S Duncan. The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy.
Epilepsy research.
1993 Oct; 16(2):165-74. doi:
10.1016/0920-1211(93)90031-2. [PMID: 8269915] - M E Bardgett, G T Taylor, J M Farah. Systemic NMDA treatment increases plasma ACTH in the neonatal female and male rat.
Brain research. Developmental brain research.
1992 Aug; 68(2):289-93. doi:
10.1016/0165-3806(92)90074-7. [PMID: 1327582] - M Chen, R Bullock, D I Graham, P Frey, D Lowe, J McCulloch. Evaluation of a competitive NMDA antagonist (D-CPPene) in feline focal cerebral ischemia.
Annals of neurology.
1991 Jul; 30(1):62-70. doi:
10.1002/ana.410300112. [PMID: 1834008] - S Patel, A G Chapman, J L Graham, B S Meldrum, P Frey. Anticonvulsant activity of the NMDA antagonists, D(-)4-(3-phosphonopropyl) piperazine-2-carboxylic acid (D-CPP) and D(-)(E)-4-(3-phosphonoprop-2-enyl) piperazine-2-carboxylic acid (D-CPPene) in a rodent and a primate model of reflex epilepsy.
Epilepsy research.
1990 Sep; 7(1):3-10. doi:
10.1016/0920-1211(90)90049-2. [PMID: 2292244]
