Fluvoxamine, (Z)- (BioDeep_00000843637)

   


代谢物信息卡片


Fluvoxamine, (Z)-

化学式: C15H21F3N2O2 (318.1555042)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F
InChI: InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14-

描述信息

同义名列表

1 个代谢物同义名

Fluvoxamine, (Z)-



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Furong Zhang, Wenting Gong, Zhou Cui, Jing Li, Yuanyuan Lu. Rhabdomyolysis in a male adolescent associated with monotherapy of fluvoxamine. European journal of hospital pharmacy : science and practice. 2022 Dec; ?(?):. doi: 10.1136/ejhpharm-2022-003533. [PMID: 36460460]
  • Thang L Pham, Azucena H Kakazu, Jiucheng He, Robert Nshimiyimana, Nicos A Petasis, Bokkyoo Jun, Nicolas G Bazan, Haydee E P Bazan. Elucidating the structure and functions of Resolvin D6 isomers on nerve regeneration with a distinctive trigeminal transcriptome. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 08; 35(8):e21775. doi: 10.1096/fj.202100686r. [PMID: 34245621]
  • Markus Blaess, Lars Kaiser, Oliver Sommerfeld, René Csuk, Hans-Peter Deigner. Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19. International journal of molecular sciences. 2021 Feb; 22(4):. doi: 10.3390/ijms22041797. [PMID: 33670304]
  • Vikas P Sukhatme, Angela M Reiersen, Sharat J Vayttaden, Vidula V Sukhatme. Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19. Frontiers in pharmacology. 2021; 12(?):652688. doi: 10.3389/fphar.2021.652688. [PMID: 33959018]
  • Luis H A Costa, Bruna M Santos, Luiz G S Branco. Can selective serotonin reuptake inhibitors have a neuroprotective effect during COVID-19?. European journal of pharmacology. 2020 Dec; 889(?):173629. doi: 10.1016/j.ejphar.2020.173629. [PMID: 33022271]
  • Eric J Lenze, Caline Mattar, Charles F Zorumski, Angela Stevens, Julie Schweiger, Ginger E Nicol, J Philip Miller, Lei Yang, Michael Yingling, Michael S Avidan, Angela M Reiersen. Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial. JAMA. 2020 12; 324(22):2292-2300. doi: 10.1001/jama.2020.22760. [PMID: 33180097]
  • Wei Zheng, Ying-Qiang Xiang, Dong-Bin Cai, Xin-Hu Yang, Ling Zhang, Wei Zheng, Xiao-Bing Lu, Yan-Ming Tong, Xiong Huang, Gabor S Ungvari, Kang Sim, Yu-Ping Ning, Yu-Tao Xiang. Adjunctive Fluvoxamine for Schizophrenia: A Meta-analysis of Randomized Double-Blind, Placebo-Controlled Trials. Journal of clinical psychopharmacology. 2020 Jul; 40(4):386-390. doi: 10.1097/jcp.0000000000001245. [PMID: 32618683]
  • Rintaro Ohno, Hiroko Miyagishi, Minoru Tsuji, Atsumi Saito, Kazuya Miyagawa, Kazuhiro Kurokawa, Hiroshi Takeda. Yokukansan, a traditional Japanese herbal medicine, enhances the anxiolytic effect of fluvoxamine and reduces cortical 5-HT2A receptor expression in mice. Journal of ethnopharmacology. 2018 Apr; 216(?):89-96. doi: 10.1016/j.jep.2018.01.032. [PMID: 29382554]
  • Ernest Dallé, Willie M U Daniels, Musa V Mabandla. Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory. Brain research bulletin. 2017 06; 132(?):75-81. doi: 10.1016/j.brainresbull.2017.05.014. [PMID: 28549887]
  • Ernest Dallé, Willie M U Daniels, Musa V Mabandla. Fluvoxamine maleate normalizes striatal neuronal inflammatory cytokine activity in a Parkinsonian rat model associated with depression. Behavioural brain research. 2017 01; 316(?):189-196. doi: 10.1016/j.bbr.2016.08.005. [PMID: 27569183]
  • Kenji Hashimoto. Activation of sigma-1 receptor chaperone in the treatment of neuropsychiatric diseases and its clinical implication. Journal of pharmacological sciences. 2015 Jan; 127(1):6-9. doi: 10.1016/j.jphs.2014.11.010. [PMID: 25704012]
  • L M Kong, S Y Xu, H H Hu, H Zhou, H D Jiang, L S Yu, S Zeng. Identification of CYP2C19 inhibitors from phytochemicals using the recombinant human enzyme model. Die Pharmazie. 2014 May; 69(5):362-6. doi: ". [PMID: 24855828]
  • Bruno Campos, Natàlia Garcia-Reyero, Claudia Rivetti, Lynn Escalon, Tanwir Habib, Romà Tauler, Stefan Tsakovski, Benjamín Piña, Carlos Barata. Identification of metabolic pathways in Daphnia magna explaining hormetic effects of selective serotonin reuptake inhibitors and 4-nonylphenol using transcriptomic and phenotypic responses. Environmental science & technology. 2013 Aug; 47(16):9434-43. doi: 10.1021/es4012299. [PMID: 23855649]
  • Andrée E Gravel, Alexandre A Arnold, Erick J Dufourc, Isabelle Marcotte. An NMR investigation of the structure, function and role of the hERG channel selectivity filter in the long QT syndrome. Biochimica et biophysica acta. 2013 Jun; 1828(6):1494-502. doi: 10.1016/j.bbamem.2013.02.012. [PMID: 23473737]
  • Bruno Campos, Benjamín Piña, Carlos Barata C. Mechanisms of action of selective serotonin reuptake inhibitors in Daphnia magna. Environmental science & technology. 2012 Mar; 46(5):2943-50. doi: 10.1021/es203157f. [PMID: 22324381]
  • Ayesha Zafir, Anjum Ara, Naheed Banu. Invivo antioxidant status: a putative target of antidepressant action. Progress in neuro-psychopharmacology & biological psychiatry. 2009 Mar; 33(2):220-8. doi: 10.1016/j.pnpbp.2008.11.010. [PMID: 19059298]
  • E J Cobos, J M Entrena, F R Nieto, C M Cendán, E Del Pozo. Pharmacology and therapeutic potential of sigma(1) receptor ligands. Current neuropharmacology. 2008 Dec; 6(4):344-66. doi: 10.2174/157015908787386113. [PMID: 19587856]
  • Mikiko Ito, Sakiko Haito, Mari Furumoto, Yoshichika Kawai, Junji Terao, Ken-ichi Miyamoto. Approach to novel functional foods for stress control 4. Regulation of serotonin transporter by food factors. The journal of medical investigation : JMI. 2005 Nov; 52 Suppl(?):245-8. doi: 10.2152/jmi.52.245. [PMID: 16366509]
  • F M Corrigan, J Jennett. Ephedra alkaloids and brief relapse in EMDR-treated obsessive compulsive disorder. Acta psychiatrica Scandinavica. 2004 Aug; 110(2):158; author reply 159. doi: 10.1111/j.1600-0047.2004.00368.x. [PMID: 15233717]
  • Mong-Liang Lu, Hsien-Yuan Lane, Shih-Ku Lin, Kun-Po Chen, Wen-Ho Chang. Adjunctive fluvoxamine inhibits clozapine-related weight gain and metabolic disturbances. The Journal of clinical psychiatry. 2004 Jun; 65(6):766-71. doi: 10.4088/jcp.v65n0607. [PMID: 15291653]
  • Bohdan W Wasilewski. Homeopathic remedies as placebo alternatives--verification on the example of treatment of menopause-related vegetative and emotional disturbances. Science and engineering ethics. 2004 Jan; 10(1):179-88. doi: 10.1007/s11948-004-0075-8. [PMID: 14986784]
  • M Inazu, H Takeda, H Ikoshi, M Sugisawa, Y Uchida, T Matsumiya. Pharmacological characterization and visualization of the glial serotonin transporter. Neurochemistry international. 2001 Jul; 39(1):39-49. doi: 10.1016/s0197-0186(01)00010-9. [PMID: 11311448]
  • M Tatsumi, K Groshan, R D Blakely, E Richelson. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. European journal of pharmacology. 1997 Dec; 340(2-3):249-58. doi: 10.1016/s0014-2999(97)01393-9. [PMID: 9537821]