(R)-Ketamine (BioDeep_00000843625)
代谢物信息卡片
(R)-Ketamine
化学式: C13H16ClNO (237.092)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNC1(CCCCC1=O)C2=CC=CC=C2Cl
InChI: InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m1/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Henry A Lester, Julie M Miwa, Rahul Srinivasan. Psychiatric drugs bind to classical targets within early exocytotic pathways: therapeutic effects.
Biological psychiatry.
2012 Dec; 72(11):907-15. doi:
10.1016/j.biopsych.2012.05.020. [PMID: 22771239] - Kaoqi Lian, Pingping Zhang, Lingmei Niu, Siyuan Bi, Shipeng Liu, Lingling Jiang, Weijun Kang. A novel derivatization approach for determination of ketamine in urine and plasma by gas chromatography-mass spectrometry.
Journal of chromatography. A.
2012 Nov; 1264(?):104-9. doi:
10.1016/j.chroma.2012.09.058. [PMID: 23058940] - Branka Sosic-Jurjevic, Branko Filipovic, Kostja Renko, Vladimir Ajdzanovic, Milica Manojlovic-Stojanoski, Verica Milosevic, Josef Köhrle. Orchidectomy of middle-aged rats decreases liver deiodinase 1 and pituitary deiodinase 2 activity.
The Journal of endocrinology.
2012 Nov; 215(2):247-56. doi:
10.1530/joe-12-0336. [PMID: 22956722] - Clarissa S Gama, Lara Canever, Bruna Panizzutti, Carolina Gubert, Laura Stertz, Raffael Massuda, Mariana Pedrini, David F de Lucena, Renata D Luca, Daiane B Fraga, Alexandra S Heylmann, Pedro F Deroza, Alexandra I Zugno. Effects of omega-3 dietary supplement in prevention of positive, negative and cognitive symptoms: a study in adolescent rats with ketamine-induced model of schizophrenia.
Schizophrenia research.
2012 Nov; 141(2-3):162-7. doi:
10.1016/j.schres.2012.08.002. [PMID: 22954755] - Zeruesenay Desta, Ruin Moaddel, Evan T Ogburn, Cong Xu, Anuradha Ramamoorthy, Swarajya Lakshmi Vattem Venkata, Mitesh Sanghvi, Michael E Goldberg, Marc C Torjman, Irving W Wainer. Stereoselective and regiospecific hydroxylation of ketamine and norketamine.
Xenobiotica; the fate of foreign compounds in biological systems.
2012 Nov; 42(11):1076-87. doi:
10.3109/00498254.2012.685777. [PMID: 22612619] - Marko A Peltoniemi, Teijo I Saari, Nora M Hagelberg, Kari Laine, Kaisa J Kurkinen, Pertti J Neuvonen, Klaus T Olkkola. Rifampicin has a profound effect on the pharmacokinetics of oral S-ketamine and less on intravenous S-ketamine.
Basic & clinical pharmacology & toxicology.
2012 Nov; 111(5):325-32. doi:
10.1111/j.1742-7843.2012.00908.x. [PMID: 22676424] - Ingrid A Lua, Shiou-Ling Lin, Huei R Lin, Ahai C Lua. Replacing immunoassays for mephedrone, ketamines and six amphetamine-type stimulants with flow injection analysis tandem mass spectrometry.
Journal of analytical toxicology.
2012 Oct; 36(8):575-81. doi:
10.1093/jat/bks068. [PMID: 22933658] - Mohammad Ashrafzadeh Takhtfooladi, Amirali Jahanshahi, Gholamreza Jahanshahi, Amir Sotoudeh, Hamed Ashrafzadeh Takhtfooladi, Mohammadreza Khansari. Protective effect of N-acetylcysteine on kidney as a remote organ after skeletal muscle ischemia-reperfusion.
Acta cirurgica brasileira.
2012 Sep; 27(9):611-5. doi:
10.1590/s0102-86502012000900004. [PMID: 22936085] - M S M Wai, W M Chan, A Q Zhang, Y Wu, D T Yew. Long-term ketamine and ketamine plus alcohol treatments produced damages in liver and kidney.
Human & experimental toxicology.
2012 Sep; 31(9):877-86. doi:
10.1177/0960327112436404. [PMID: 22354085] - Erik Olofsen, Marnix Sigtermans, Ingeborg Noppers, Marieke Niesters, Rene Mooren, Martin Bauer, Leon Aarts, Elise Sarton, Albert Dahan. The dose-dependent effect of S(+)-ketamine on cardiac output in healthy volunteers and complex regional pain syndrome type 1 chronic pain patients.
Anesthesia and analgesia.
2012 Sep; 115(3):536-46. doi:
10.1213/ane.0b013e31825496f6. [PMID: 22575567] - Oz Malkesman, Daniel R Austin, Tyson Tragon, Gang Wang, Gregory Rompala, Anahita B Hamidi, Zhenzhong Cui, W Scott Young, Kazu Nakazawa, Carlos A Zarate, Husseini K Manji, Guang Chen. Acute D-serine treatment produces antidepressant-like effects in rodents.
The international journal of neuropsychopharmacology.
2012 Sep; 15(8):1135-48. doi:
10.1017/s1461145711001386. [PMID: 21906419] - Yi-Chun Ma, Che-Wei Wang, Sih-Hua Hung, Yan-Zin Chang, Chia-Reiy Liu, Guor-Rong Her. Estimation of the measurement uncertainty in quantitative determination of ketamine and norketamine in urine using a one-point calibration method.
Journal of analytical toxicology.
2012 Sep; 36(7):515-22. doi:
10.1093/jat/bks062. [PMID: 22825634] - Carlos A Zarate, Nancy Brutsche, Gonzalo Laje, David A Luckenbaugh, Swarajya L Vattem Venkata, Anuradha Ramamoorthy, Ruin Moaddel, Irving W Wainer. Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression.
Biological psychiatry.
2012 Aug; 72(4):331-8. doi:
10.1016/j.biopsych.2012.03.004. [PMID: 22516044] - I Lueders, I Luther, G Scheepers, G van der Horst. Improved semen collection method for wild felids: urethral catheterization yields high sperm quality in African lions (Panthera leo).
Theriogenology.
2012 Aug; 78(3):696-701. doi:
10.1016/j.theriogenology.2012.02.026. [PMID: 22538007] - Nicolò Columbano, Fabio Secci, Giovanni M Careddu, Giovanni Sotgiu, Gabriele Rossi, Bernd Driessen. Effects of lidocaine constant rate infusion on sevoflurane requirement, autonomic responses, and postoperative analgesia in dogs undergoing ovariectomy under opioid-based balanced anesthesia.
Veterinary journal (London, England : 1997).
2012 Aug; 193(2):448-55. doi:
10.1016/j.tvjl.2011.12.005. [PMID: 22261004] - Erik Olofsen, Ingeborg Noppers, Marieke Niesters, Evan Kharasch, Leon Aarts, Elise Sarton, Albert Dahan. Estimation of the contribution of norketamine to ketamine-induced acute pain relief and neurocognitive impairment in healthy volunteers.
Anesthesiology.
2012 Aug; 117(2):353-64. doi:
10.1097/aln.0b013e31825b6c91. [PMID: 22692377] - Xiaochen Zhao, Swarajya Lakshmi Vattem Venkata, Ruin Moaddel, Dave A Luckenbaugh, Nancy E Brutsche, Lobna Ibrahim, Carlos A Zarate, Donald E Mager, Irving W Wainer. Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.
British journal of clinical pharmacology.
2012 Aug; 74(2):304-14. doi:
10.1111/j.1365-2125.2012.04198.x. [PMID: 22295895] - Hitoshi Yoshida, Tomoyuki Kudo, Masahiro Sawada, Junichi Saito, Mitsuru Tonosaki, Kazuyoshi Hirota. [Effects of propofol and ketamine on postoperative hepatic and renal function: comparison between fentanyl and remifentanil as an adjuvant].
Masui. The Japanese journal of anesthesiology.
2012 Aug; 61(8):794-9. doi:
NULL. [PMID: 22991797] - Angela Hefti, Inka Schlemmer, Carola Sauter-Louis, Moritz Metzner. [Comparison of three different anesthesia procedures in calves with respect to possible pain-associated reactions].
Berliner und Munchener tierarztliche Wochenschrift.
2012 Jul; 125(7-8):315-25. doi:
NULL. [PMID: 22919925] - Emine Arzu Kose, Bulent Bakar, Sebnem Kupana Ayva, Kamer Kilinc, Alpaslan Apan. Neuroprotective effects of racemic ketamine and (S)-ketamine on spinal cord injury in rat.
Injury.
2012 Jul; 43(7):1124-30. doi:
10.1016/j.injury.2012.02.022. [PMID: 22436574] - Seok Hwa Yoon. Concerns of the anesthesiologist: anesthetic induction in severe sepsis or septic shock patients.
Korean journal of anesthesiology.
2012 Jul; 63(1):3-10. doi:
10.4097/kjae.2012.63.1.3. [PMID: 22870358] - Derrek A Heuveling, Gerard W M Visser, Mattijs de Groot, Johannes F de Boer, Marian Baclayon, Wouter H Roos, Gijs J L Wuite, C René Leemans, Remco de Bree, Guus A M S van Dongen. Nanocolloidal albumin-IRDye 800CW: a near-infrared fluorescent tracer with optimal retention in the sentinel lymph node.
European journal of nuclear medicine and molecular imaging.
2012 Jul; 39(7):1161-8. doi:
10.1007/s00259-012-2080-5. [PMID: 22349719] - Sheila R Ernest, Michael G Wade, Claudia Lalancette, Yi-Qian Ma, Robert G Berger, Bernard Robaire, Barbara F Hales. Effects of chronic exposure to an environmentally relevant mixture of brominated flame retardants on the reproductive and thyroid system in adult male rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2012 Jun; 127(2):496-507. doi:
10.1093/toxsci/kfs098. [PMID: 22387749] - İlhan Gecit, Servet Kavak, Ismail Meral, Mustafa Güneş, Necip Pirinççi, Fuat Sayir, Halit Demir, Kadir Ceylan. Effects of shock waves on oxidative stress and some trace element levels of rat liver and diaphragm muscles.
Cell biochemistry and function.
2012 Jun; 30(4):303-8. doi:
10.1002/cbf.2802. [PMID: 22247008] - Edward C Lauterbach. An extension of hypotheses regarding rapid-acting, treatment-refractory, and conventional antidepressant activity of dextromethorphan and dextrorphan.
Medical hypotheses.
2012 Jun; 78(6):693-702. doi:
10.1016/j.mehy.2012.02.012. [PMID: 22401777] - Kristina Yasmin Rust, Markus R Baumgartner, Annika M Dally, Thomas Kraemer. Prevalence of new psychoactive substances: A retrospective study in hair.
Drug testing and analysis.
2012 Jun; 4(6):402-8. doi:
10.1002/dta.1338. [PMID: 22522922] - Michael Maes, Zdenĕk Fišar, Miguel Medina, Giovanni Scapagnini, Gabriel Nowak, Michael Berk. New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates--Nrf2 activators and GSK-3 inhibitors.
Inflammopharmacology.
2012 Jun; 20(3):127-50. doi:
10.1007/s10787-011-0111-7. [PMID: 22271002] - Jennifer E Shields, Paul I Dargan, David M Wood, Malgorzata Puchnarewicz, Susannah Davies, W Stephen Waring. Methoxetamine associated reversible cerebellar toxicity: three cases with analytical confirmation.
Clinical toxicology (Philadelphia, Pa.).
2012 Jun; 50(5):438-40. doi:
10.3109/15563650.2012.683437. [PMID: 22578175] - Marko A Peltoniemi, Teijo I Saari, Nora M Hagelberg, Kari Laine, Pertti J Neuvonen, Klaus T Olkkola. S-ketamine concentrations are greatly increased by grapefruit juice.
European journal of clinical pharmacology.
2012 Jun; 68(6):979-86. doi:
10.1007/s00228-012-1214-9. [PMID: 22286159] - Pascal Kintz. Value of the concept of minimal detectable dosage in human hair.
Forensic science international.
2012 May; 218(1-3):28-30. doi:
10.1016/j.forsciint.2011.10.018. [PMID: 22018745] - M Ertugrul Kafali, Mehmet Gul, Husnu Alptekin, Mustafa Sahin, Hatice Toy, Mehmet Akoz. Is there a relationship between beginning time and efficiency of octreotide in the treatment of experimental acute pancreatitis?.
Journal of the Korean Surgical Society.
2012 May; 82(5):296-301. doi:
10.4174/jkss.2012.82.5.296. [PMID: 22563536] - Adnan T Bhutta, Michael L Schmitz, Christopher Swearingen, Laura P James, Wendy L Wardbegnoche, Diana M Lindquist, Charles M Glasier, Volkan Tuzcu, Parthak Prodhan, Umesh Dyamenahalli, Michiaki Imamura, Robert D B Jaquiss, Kanwaljeet J S Anand. Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.
2012 May; 13(3):328-37. doi:
10.1097/pcc.0b013e31822f18f9. [PMID: 21926656] - Alonso G P Guedes, Nora S Matthews, David M Hood. Effect of ketamine hydrochloride on the analgesic effects of tramadol hydrochloride in horses with signs of chronic laminitis-associated pain.
American journal of veterinary research.
2012 May; 73(5):610-9. doi:
10.2460/ajvr.73.5.610. [PMID: 22533391] - David M Wood, Susannah Davies, Malgorzata Puchnarewicz, Atholl Johnston, Paul I Dargan. Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine.
European journal of clinical pharmacology.
2012 May; 68(5):853-6. doi:
10.1007/s00228-011-1199-9. [PMID: 22205276] - Catherine M Creighton, Kip A Lemke, Leigh A Lamont, Barbara S Horney, Aimie J Doyle. Comparison of the effects of xylazine bolus versus medetomidine constant rate infusion on the stress response, urine production, and anesthetic recovery characteristics in horses anesthetized with isoflurane.
Journal of the American Veterinary Medical Association.
2012 Apr; 240(8):998-1002. doi:
10.2460/javma.240.8.998. [PMID: 22471830] - Amany K Elshorbagy, Chris Church, Maria Valdivia-Garcia, A David Smith, Helga Refsum, Roger Cox. Dietary cystine level affects metabolic rate and glycaemic control in adult mice.
The Journal of nutritional biochemistry.
2012 Apr; 23(4):332-40. doi:
10.1016/j.jnutbio.2010.12.009. [PMID: 21543215] - Servet Kavak, M Fatih Garca, Ilhan Gecit, Ismail Meral, Nurettin Cengiz, Halit Demir. Effects of extracorporeal shock-wave lithotripsy directed at the parotid gland on oxidative stress parameters and some trace element levels in facial nerve of rats.
Muscle & nerve.
2012 Apr; 45(4):562-6. doi:
10.1002/mus.22326. [PMID: 22431090] - Manavi Chatterjee, Seema Singh, Reena Kumari, Anil Kumar Verma, Gautam Palit. Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice.
Neurochemical research.
2012 Apr; 37(4):759-70. doi:
10.1007/s11064-011-0670-4. [PMID: 22189635] - Qing Fang, Alicia M Giordimaina, David F Dolan, Sally A Camper, Mirna Mustapha. Genetic background of Prop1(df) mutants provides remarkable protection against hypothyroidism-induced hearing impairment.
Journal of the Association for Research in Otolaryngology : JARO.
2012 Apr; 13(2):173-184. doi:
10.1007/s10162-011-0302-3. [PMID: 22143287] - Eun Young Kim, Joon Seok Choi, Ko Eun Lee, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Suhn Hee Kim, Jong Un Lee, Soo Wan Kim. Altered regulation of renal Acid base transporters in response to ammonium chloride loading in rats.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.
2012 Apr; 16(2):91-5. doi:
10.4196/kjpp.2012.16.2.91. [PMID: 22563253] - Mujalin Prasannarong, Vitoon Saengsirisuwan, Pawinee Piyachaturawat, Apichart Suksamrarn. Improvements of insulin resistance in ovariectomized rats by a novel phytoestrogen from Curcuma comosa Roxb.
BMC complementary and alternative medicine.
2012 Mar; 12(?):28. doi:
10.1186/1472-6882-12-28. [PMID: 22463706] - Yi Wang, Lin Lin, Chunquan Zheng. Downregulation of Orai1 expression in the airway alleviates murine allergic rhinitis.
Experimental & molecular medicine.
2012 Mar; 44(3):177-90. doi:
10.3858/emm.2012.44.3.013. [PMID: 22170034] - Michael Oster, Eduard Murani, Cornelia C Metges, Siriluck Ponsuksili, Klaus Wimmers. A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model.
BMC genomics.
2012 Mar; 13(?):93. doi:
10.1186/1471-2164-13-93. [PMID: 22424151] - László Héja, Gabriella Nyitrai, Orsolya Kékesi, Arpád Dobolyi, Pál Szabó, Richárd Fiáth, István Ulbert, Borbála Pál-Szenthe, Miklós Palkovits, Julianna Kardos. Astrocytes convert network excitation to tonic inhibition of neurons.
BMC biology.
2012 Mar; 10(?):26. doi:
10.1186/1741-7007-10-26. [PMID: 22420899] - Eduardo G Victor, Paulo C L Silveira, Jonathann C Possato, Guilherme L da Rosa, Uillian B Munari, Claudio T de Souza, Ricardo A Pinho, Luciano da Silva, Emilio L Streck, Marcos M S Paula. Pulsed ultrasound associated with gold nanoparticle gel reduces oxidative stress parameters and expression of pro-inflammatory molecules in an animal model of muscle injury.
Journal of nanobiotechnology.
2012 Mar; 10(?):11. doi:
10.1186/1477-3155-10-11. [PMID: 22410000] - M J Mirzayan, C Probst, M Samii, C Krettek, A Gharabaghi, H C Pape, M van Griensven, A Samii. Histopathological features of the brain, liver, kidney and spleen following an innovative polytrauma model of the mouse.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2012 Mar; 64(3):133-9. doi:
10.1016/j.etp.2010.07.007. [PMID: 20688496] - Firoz N Momin, Bharatesh R Kalai, Tabassum S Shikalgar, Nilofar S Naikwade. Cardioprotective effect of methanolic extract of Ixora coccinea Linn. leaves on doxorubicin-induced cardiac toxicity in rats.
Indian journal of pharmacology.
2012 Mar; 44(2):178-83. doi:
10.4103/0253-7613.93844. [PMID: 22529471] - Ellen Gutkin, Syed A Hussain, Sang H Kim. Ketamine-induced biliary dilatation: from Hong Kong to New York.
Journal of addiction medicine.
2012 Mar; 6(1):89-91. doi:
10.1097/adm.0b013e3182399216. [PMID: 22124288] - Wouter Bult, Hendrik de Leeuw, Olav M Steinebach, Martijn J van der Bom, Hubert Th Wolterbeek, Ron M A Heeren, Chris J G Bakker, Alfred D van Het Schip, Wim E Hennink, J Frank W Nijsen. Radioactive holmium acetylacetonate microspheres for interstitial microbrachytherapy: an in vitro and in vivo stability study.
Pharmaceutical research.
2012 Mar; 29(3):827-36. doi:
10.1007/s11095-011-0610-7. [PMID: 22068276] - Deepak Cyril D'Souza, Nagendra Singh, Jacqueline Elander, Michelle Carbuto, Brian Pittman, Joanna Udo de Haes, Magnus Sjogren, Pierre Peeters, Mohini Ranganathan, Jacques Schipper. Glycine transporter inhibitor attenuates the psychotomimetic effects of ketamine in healthy males: preliminary evidence.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2012 Mar; 37(4):1036-46. doi:
10.1038/npp.2011.295. [PMID: 22113087] - Kirsten Biermann, Stephan Hungerbühler, Reinhard Mischke, Sabine B R Kästner. Sedative, cardiovascular, haematologic and biochemical effects of four different drug combinations administered intramuscularly in cats.
Veterinary anaesthesia and analgesia.
2012 Mar; 39(2):137-50. doi:
10.1111/j.1467-2995.2011.00699.x. [PMID: 22356415] - Christopher D Rosenbaum, Stephanie P Carreiro, Kavita M Babu. Here today, gone tomorrow…and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones (bath salts), kratom, Salvia divinorum, methoxetamine, and piperazines.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2012 Mar; 8(1):15-32. doi:
10.1007/s13181-011-0202-2. [PMID: 22271566] - Hasan K Pampal, Yusuf Unal, Cengiz B Demirel, Aynur Albayrak, Omer Kurtipek, Alper Murat, Mustafa Arslan, Mustafa Kavutcu. The effects of sevoflurane and propofol anesthesia on renal sodium-potassium adenosine triphosphatase activity during pneumoperitoneum in rats.
Saudi medical journal.
2012 Mar; 33(3):244-9. doi:
NULL. [PMID: 22426903] - Ibrahim Abdel Aziz Ibrahim, Yusof Kamisah, Mohd Ismail Nafeeza, Mohd Fahami Nur Azlina. The effects of palm vitamin E on stress hormone levels and gastric lesions in stress-induced rats.
Archives of medical science : AMS.
2012 Feb; 8(1):22-9. doi:
10.5114/aoms.2012.27276. [PMID: 22457670] - Hyeyoung Choi, Seungkyung Baeck, Moonhee Jang, Sooyeun Lee, Hwakyung Choi, Heesun Chung. Simultaneous analysis of psychotropic phenylalkylamines in oral fluid by GC-MS with automated SPE and its application to legal cases.
Forensic science international.
2012 Feb; 215(1-3):81-7. doi:
10.1016/j.forsciint.2011.02.011. [PMID: 21377815] - Paulien Gm Ravenstijn, Henk-Jan Drenth, Michael J O'Neill, Meindert Danhof, Elizabeth Cm de Lange. Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease.
Fluids and barriers of the CNS.
2012 Feb; 9(?):4. doi:
10.1186/2045-8118-9-4. [PMID: 22316420] - Yu-Che Cheng, Kun-Han Chen, Juo-Shin Wang, Wen-Liu Hsu, Chih-Cheng Chien, Wen-Yih Chen, Chia-Wen Tsao. Rapid analysis of abused drugs using nanostructured silicon surface assisted laser desorption/ionization mass spectrometry.
The Analyst.
2012 Feb; 137(3):654-61. doi:
10.1039/c1an15913e. [PMID: 22146524] - Peide Li, Hangru Han, Xiaohu Zhai, Weihua He, Liying Sun, Jiafa Hou. Simultaneous HPLC-UV determination of ketamine, xylazine, and midazolam in canine plasma.
Journal of chromatographic science.
2012 Feb; 50(2):108-13. doi:
10.1093/chromsci/bmr036. [PMID: 22298759] - Jin Young Kim, Jung Yeon Ghee, Sun Woo Lim, Shang Guo Piao, Byung Ha Chung, Hye Eun Yoon, Hyeon Seok Hwang, Bum Soon Choi, Jin Kim, Chul Woo Yang. Comparison of early and late conversion of sirolimus in experimental model of chronic cyclosporine nephropathy.
Journal of Korean medical science.
2012 Feb; 27(2):160-9. doi:
10.3346/jkms.2012.27.2.160. [PMID: 22323863] - Hossein Zhaleh, Mehri Azadbakht, Ali Bidmeshki Pour. Possible involvement of calcium channels and plasma membrane receptors on Staurosporine-induced neurite outgrowth.
Bosnian journal of basic medical sciences.
2012 Feb; 12(1):20-5. doi:
10.17305/bjbms.2012.2526. [PMID: 22364299] - Brice S Reynolds, Anne Geffré, Nathalie H Bourgès-Abella, Sophie Vaucoret, Maité Mourot, Jean-Pierre D Braun, Catherine Trumel. Effects of intravenous, low-dose ketamine-diazepam sedation on the results of hematologic, plasma biochemical, and coagulation analyses in cats.
Journal of the American Veterinary Medical Association.
2012 Feb; 240(3):287-93. doi:
10.2460/javma.240.3.287. [PMID: 22256843] - Shuyu Zhang, Chuanjun Song, Jundong Zhou, Ling Xie, Xingjun Meng, Pengfei Liu, Jianping Cao, Xueguang Zhang, Wei-Qun Ding, Jinchang Wu. Amelioration of radiation-induced skin injury by adenovirus-mediated heme oxygenase-1 (HO-1) overexpression in rats.
Radiation oncology (London, England).
2012 Jan; 7(?):4. doi:
10.1186/1748-717x-7-4. [PMID: 22247972] - Marcel Binnebösel, Klaus T von Trotha, Christina Ricken, Christian D Klink, Karsten Junge, Joachim Conze, Marc Jansen, Ulf P Neumann, Petra Lynen Jansen. Gentamicin supplemented polyvinylidenfluoride mesh materials enhance tissue integration due to a transcriptionally reduced MMP-2 protein expression.
BMC surgery.
2012 Jan; 12(?):1. doi:
10.1186/1471-2482-12-1. [PMID: 22244356] - Hui Chen, Julie-Thu A Tran, Robert E Anderson, Md Nawajes A Mandal. Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats.
Molecular vision.
2012; 18(?):1325-38. doi:
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Clinics (Sao Paulo, Brazil).
2012; 67(5):497-502. doi:
10.6061/clinics/2012(05)15. [PMID: 22666795] - Abdoljalal Marjani, Reza Rahmati, Azad Reza Mansourian, Gholamreza Veghary. Effect of peppermint oil on serum lipid peroxidation and hepatic enzymes after immobility stress in mice.
The open biochemistry journal.
2012; 6(?):51-5. doi:
10.2174/1874091x01206010051. [PMID: 22654997] - Ashley E Laing, Leonard K Seibold, Jeffrey R SooHoo, Malik Y Kahook. Evaluation of bleb characteristics after implantation of the EX-PRESS™ glaucoma filtration device.
Molecular vision.
2012; 18(?):10-3. doi:
NULL. [PMID: 22232564] - Gábor Eros, Petra Hartmann, Szilvia Berkó, Eszter Csizmazia, Erzsébet Csányi, Anita Sztojkov-Ivanov, István Németh, Piroska Szabó-Révész, István Zupkó, Lajos Kemény. A novel murine model for the in vivo study of transdermal drug penetration.
TheScientificWorldJournal.
2012; 2012(?):543536. doi:
10.1100/2012/543536. [PMID: 22272176] - Yongqing Lai, Song Wu, Liangchao Ni, Zebo Chen, Xianxin Li, Shangqi Yang, Yaoting Gui, Zhichen Guan, Zhiming Cai, Jiongxian Ye. Ketamine-associated urinary tract dysfunction: an underrecognized clinical entity.
Urologia internationalis.
2012; 89(1):93-6. doi:
10.1159/000338098. [PMID: 22710265] - Eugenia Murawska-Ciałowicz, Wojciech Bal, Lidia Januszewska, Marcin Zawadzki, Joanna Rychel, Jolanta Zuwała-Jagiełło. Oxidative stress level in the testes of mice and rats during nickel intoxication.
TheScientificWorldJournal.
2012; 2012(?):395741. doi:
10.1100/2012/395741. [PMID: 22448131] - G Kocic, J Nikolic, T Jevtovic-Stoimenov, D Sokolovic, H Kocic, T Cvetkovic, D Pavlovic, A Cencic, D Stojanovic. L-arginine intake effect on adenine nucleotide metabolism in rat parenchymal and reproductive tissues.
TheScientificWorldJournal.
2012; 2012(?):208239. doi:
10.1100/2012/208239. [PMID: 22623885] - G C Musk, J D Netto, G L Maker, R D Trengove. Transplacental transfer of medetomidine and ketamine in pregnant ewes.
Laboratory animals.
2012 Jan; 46(1):46-50. doi:
10.1258/la.2011.010179. [PMID: 22008849] - Ian Mahar, Rosemary C Bagot, Maria Antonietta Davoli, Sharon Miksys, Rachel F Tyndale, Claire-Dominique Walker, Marissa Maheu, Sheng-Hai Huang, Tak Pan Wong, Naguib Mechawar. Developmental hippocampal neuroplasticity in a model of nicotine replacement therapy during pregnancy and breastfeeding.
PloS one.
2012; 7(5):e37219. doi:
10.1371/journal.pone.0037219. [PMID: 22615944] - Jung Pyo Lee, Seung Hee Yang, Hee-Yoon Lee, Bora Kim, Joo-Youn Cho, Jin Ho Paik, Yun Jung Oh, Dong Ki Kim, Chun Soo Lim, Yon Su Kim. Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney.
PloS one.
2012; 7(5):e37075. doi:
10.1371/journal.pone.0037075. [PMID: 22590647] - Kemal Simsek, Mehmet Ozler, Ali Osman Yildirim, Serdar Sadir, Seref Demirbas, Muzaffer Oztosun, Ahmet Korkmaz, Hakan Ay, Sukru Oter, Senol Yildiz. Evaluation of the oxidative effect of long-term repetitive hyperbaric oxygen exposures on different brain regions of rats.
TheScientificWorldJournal.
2012; 2012(?):849183. doi:
10.1100/2012/849183. [PMID: 22454610] - Galina Dvoriantchikova, Dmitry Ivanov, David Barakat, Alexander Grinberg, Rong Wen, Vladlen Z Slepak, Valery I Shestopalov. Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury.
PloS one.
2012; 7(2):e31991. doi:
10.1371/journal.pone.0031991. [PMID: 22384122] - Leif Oxburgh, Mark P de Caestecker. Ischemia-reperfusion injury of the mouse kidney.
Methods in molecular biology (Clifton, N.J.).
2012; 886(?):363-79. doi:
10.1007/978-1-61779-851-1_32. [PMID: 22639277] - Peter F Mount, Kurt Gleich, Shanna Tam, Scott A Fraser, Suet-Wan Choy, Karen M Dwyer, Bo Lu, Bryce Van Denderen, Günter Fingerle-Rowson, Richard Bucala, Bruce E Kemp, David A Power. The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice.
PloS one.
2012; 7(1):e29887. doi:
10.1371/journal.pone.0029887. [PMID: 22253816] - Emmanuel E Douzinas, Olga Livaditi, Marios-Konstantinos Tasoulis, Panagiotis Prigouris, Dimitrios Bakos, Nikolaos Goutas, Dimitrios Vlachodimitropoulos, Ilias Andrianakis, Alex Betrosian, George D Tsoukalas. Nitrosative and oxidative stresses contribute to post-ischemic liver injury following severe hemorrhagic shock: the role of hypoxemic resuscitation.
PloS one.
2012; 7(3):e32968. doi:
10.1371/journal.pone.0032968. [PMID: 22403729] - Manohar B Mutnal, Shuxian Hu, James R Lokensgard. Persistent humoral immune responses in the CNS limit recovery of reactivated murine cytomegalovirus.
PloS one.
2012; 7(3):e33143. doi:
10.1371/journal.pone.0033143. [PMID: 22412996] - Mustafa Arslan, Faruk Metin Çomu, Ayşegül Küçük, Levent Oztürk, Faik Yaylak. Dexmedetomidine protects against lipid peroxidation and erythrocyte deformability alterations in experimental hepatic ischemia reperfusion injury.
The Libyan journal of medicine.
2012; 7(?):. doi:
10.3402/ljm.v7i0.18185. [PMID: 22645631] - Cornelia C Metges, Iris S Lang, Ulf Hennig, Klaus-Peter Brüssow, Ellen Kanitz, Margret Tuchscherer, Falk Schneider, Joachim M Weitzel, Anika Steinhoff-Ooster, Helga Sauerwein, Olaf Bellmann, Gerd Nürnberg, Charlotte Rehfeldt, Winfried Otten. Intrauterine growth retarded progeny of pregnant sows fed high protein:low carbohydrate diet is related to metabolic energy deficit.
PloS one.
2012; 7(2):e31390. doi:
10.1371/journal.pone.0031390. [PMID: 22328932] - Andreja Erman, Katja Lakota, Katjusa Mrak-Poljsak, Matthew G Blango, Veronika Krizan-Hergouth, Matthew A Mulvey, Snezna Sodin-Semrl, Peter Veranic. Uropathogenic Escherichia coli induces serum amyloid a in mice following urinary tract and systemic inoculation.
PloS one.
2012; 7(3):e32933. doi:
10.1371/journal.pone.0032933. [PMID: 22427910] - Fouad Al-Bayaty, Mahmood Ameen Abdulla. A comparison of wound healing rate following treatment with aftamed and chlorine dioxide gels in streptozotocin-induced diabetic rats.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):468764. doi:
10.1155/2012/468764. [PMID: 22666291] - Xin Zhang, Bin Cheng, Xianghong Jing, Yongfa Qiao, Xinyan Gao, Huijuan Yu, Bing Zhu, Haifa Qiao. NMDA Receptors of Gastric-Projecting Neurons in the Dorsal Motor Nucleus of the Vagus Mediate the Regulation of Gastric Emptying by EA at Weishu (BL21).
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):583479. doi:
10.1155/2012/583479. [PMID: 22654955] - Jakob Appel Østergaard, Mette Bjerre, Satish Posettihalli RamachandraRao, Kumar Sharma, Jens Randel Nyengaard, Troels Krarup Hansen, Steffen Thiel, Allan Flyvbjerg. Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model.
Experimental diabetes research.
2012; 2012(?):678381. doi:
10.1155/2012/678381. [PMID: 22645604] - Chung-Hung Shih, Ling-Hung Lin, Hsin-Te Hsu, Kuo-Hsien Wang, Chi-Yin Lai, Chien-Ming Chen, Wun-Chang Ko. Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):472897. doi:
10.1155/2012/472897. [PMID: 22454667] - Ahmed S Alrashdi, Suzy M Salama, Salim S Alkiyumi, Mahmood A Abdulla, A Hamid A Hadi, Siddig I Abdelwahab, Manal M Taha, Jamal Hussiani, Nur Asykin. Mechanisms of Gastroprotective Effects of Ethanolic Leaf Extract of Jasminum sambac against HCl/Ethanol-Induced Gastric Mucosal Injury in Rats.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):786426. doi:
10.1155/2012/786426. [PMID: 22550543] - Eugene Tkachenko, Dan Tse, Olga Sideleva, Sophie J Deharvengt, Marcus R Luciano, Yan Xu, Caitlin L McGarry, John Chidlow, Paul F Pilch, William C Sessa, Derek K Toomre, Radu V Stan. Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells.
PloS one.
2012; 7(3):e32655. doi:
10.1371/journal.pone.0032655. [PMID: 22403691] - Hiroki Matsui, Tomoyuki Yokoyama, Kenichi Sekiguchi, Daisuke Iijima, Hiroaki Sunaga, Moeno Maniwa, Manabu Ueno, Tatsuya Iso, Masashi Arai, Masahiko Kurabayashi. Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes.
PloS one.
2012; 7(3):e33283. doi:
10.1371/journal.pone.0033283. [PMID: 22413010] - Wen Chen, Birgit Gassner, Sebastian Börner, Viacheslav O Nikolaev, Nicolas Schlegel, Jens Waschke, Nadine Steinbronn, Ruth Strasser, Michaela Kuhn. Atrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway.
Cardiovascular research.
2012 Jan; 93(1):141-51. doi:
10.1093/cvr/cvr279. [PMID: 22025581] - Samo Hudoklin, Kristijan Jezernik, Josef Neumüller, Margit Pavelka, Rok Romih. Electron tomography of fusiform vesicles and their organization in urothelial cells.
PloS one.
2012; 7(3):e32935. doi:
10.1371/journal.pone.0032935. [PMID: 22427911] - Cory D Champagne, Dorian S Houser, Daniel P Costa, Daniel E Crocker. The effects of handling and anesthetic agents on the stress response and carbohydrate metabolism in northern elephant seals.
PloS one.
2012; 7(5):e38442. doi:
10.1371/journal.pone.0038442. [PMID: 22693622] - Suhailah Wasman Qader, Mahmood Ameen Abdulla, Lee Suan Chua, Hasnah Mohd Sirat, Salehhuddin Hamdan. Pharmacological mechanisms underlying gastroprotective activities of the fractions obtained from Polygonum minus in Sprague Dawley rats.
International journal of molecular sciences.
2012; 13(2):1481-1496. doi:
10.3390/ijms13021481. [PMID: 22408403] - Eleonora Cimini, Cécile Bonnafous, Veronica Bordoni, Eleonora Lalle, Helene Sicard, Alessandra Sacchi, Giulia Berno, Cristiana Gioia, Gianpiero D'Offizi, Ubaldo Visco Comandini, Chrysoula Vlassi, Maria Rosaria Capobianchi, Federico Martini, Chiara Agrati. Interferon-α improves phosphoantigen-induced Vγ9Vδ2 T-cells interferon-γ production during chronic HCV infection.
PloS one.
2012; 7(5):e37014. doi:
10.1371/journal.pone.0037014. [PMID: 22629350] - Lu Ke, Zhi-hui Tong, Hai-bin Ni, Wei-wei Ding, Jia-kui Sun, Wei-qin Li, Ning Li, Jie-shou Li. The effect of intra-abdominal hypertension incorporating severe acute pancreatitis in a porcine model.
PloS one.
2012; 7(3):e33125. doi:
10.1371/journal.pone.0033125. [PMID: 22403734] - Andreas D Flouris, Giorgos S Metsios, Andres E Carrillo, Andres E Carrill, Athanasios Z Jamurtas, Polychronis D Stivaktakis, Manolis N Tzatzarakis, Aristidis M Tsatsakis, Yiannis Koutedakis. Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
PloS one.
2012; 7(2):e31880. doi:
10.1371/journal.pone.0031880. [PMID: 22355401] - Li-Jen Lin, Chin-Che Lin, Shulhn-Der Wang, Yun-Peng Chao, Shung-Te Kao. The Immunomodulatory Effect of You-Gui-Wan on Dermatogoides-pteronyssinus-Induced Asthma.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):476060. doi:
10.1155/2012/476060. [PMID: 22675381] - Andresa Aparecida Berretta, Andresa Piacezzi Nascimento, Paula Carolina Pires Bueno, Mirela Mara de Oliveira Lima Leite Vaz, Juliana Maldonado Marchetti. Propolis standardized extract (EPP-AF®), an innovative chemically and biologically reproducible pharmaceutical compound for treating wounds.
International journal of biological sciences.
2012; 8(4):512-21. doi:
10.7150/ijbs.3641. [PMID: 22457606]
