S-Methylthiocitrulline (BioDeep_00000843618)
代谢物信息卡片
S-Methylthiocitrulline
化学式: C7H15N3O2S (205.088493)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CSC(=NCCCC(C(=O)O)N)N
InChI: InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Koichiro Homma, Koichi Hayashi, Shu Wakino, Hirobumi Tokuyama, Takeshi Kanda, Satoru Tatematsu, Kazuhiro Hasegawa, Seitaro Fujishima, Shingo Hori, Takao Saruta, Hiroshi Itoh. Rho-kinase contributes to pressure-induced constriction of renal microvessels.
The Keio journal of medicine.
2014; 63(1):1-12. doi:
10.2302/kjm.2013-0001-oa. [PMID: 24429483] - Steven W Copp, Daniel M Hirai, Gabrielle E Sims, Richard J Fels, Timothy I Musch, David C Poole, Michael J Kenney. Neuronal nitric oxide synthase inhibition and regional sympathetic nerve discharge: implications for peripheral vascular control.
Respiratory physiology & neurobiology.
2013 May; 186(3):285-9. doi:
10.1016/j.resp.2013.02.021. [PMID: 23454026] - Justin Rodebaugh, Miroslav Sekulic, William Davies, Stephanie Montgomery, Ali Khraibi, Michael J Solhaug, Brian B Ratliff. Neuronal nitric oxide synthase, nNOS, regulates renal hemodynamics in the postnatal developing piglet.
Pediatric research.
2012 Feb; 71(2):144-9. doi:
10.1038/pr.2011.23. [PMID: 22258124] - Yukio Ago, Toshiyuki Kawasaki, Tetsuaki Nashida, Yuki Ota, Yana Cong, Mari Kitamoto, Teisuke Takahashi, Kazuhiro Takuma, Toshio Matsuda. SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease.
Neuropharmacology.
2011 Dec; 61(8):1441-51. doi:
10.1016/j.neuropharm.2011.08.041. [PMID: 21903118] - M Kuczeriszka, K H Olszyński, A Gąsiorowska, J Sadowski, E Kompanowska-Jezierska. Interaction of nitric oxide and the cytochrome P-450 system on blood pressure and renal function in the rat: dependence on sodium intake.
Acta physiologica (Oxford, England).
2011 Apr; 201(4):493-502. doi:
10.1111/j.1748-1716.2010.02222.x. [PMID: 21073660] - J B Kelley, K L Anderson, S L Altmann, Y Itzhak. Long-term memory of visually cued fear conditioning: roles of the neuronal nitric oxide synthase gene and cyclic AMP response element-binding protein.
Neuroscience.
2011 Feb; 174(?):91-103. doi:
10.1016/j.neuroscience.2010.11.005. [PMID: 21073925] - Cheryl A Smith, Beth Santymire, Aaron Erdely, Vasuki Venkat, György Losonczy, Chris Baylis. Renal nitric oxide production in rat pregnancy: role of constitutive nitric oxide synthases.
American journal of physiology. Renal physiology.
2010 Oct; 299(4):F830-6. doi:
10.1152/ajprenal.00300.2010. [PMID: 20630934] - Jenny Edlund, Angelica Fasching, Per Liss, Peter Hansell, Fredrik Palm. The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney.
Diabetes/metabolism research and reviews.
2010 Jul; 26(5):349-56. doi:
10.1002/dmrr.1099. [PMID: 20583310] - Fredrik Palm, Angelica Fasching, Peter Hansell, Orjan Källskog. Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney.
American journal of physiology. Renal physiology.
2010 Feb; 298(2):F416-20. doi:
10.1152/ajprenal.00229.2009. [PMID: 19923416] - Takehito Kemuriyama, Megumi Tandai-Hiruma, Kazuo Kato, Hiroyuki Ohta, Satoshi Maruyama, Yoshiaki Sato, Yasuhiro Nishida. Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure.
The journal of physiological sciences : JPS.
2009 Jul; 59(4):275-81. doi:
10.1007/s12576-009-0034-x. [PMID: 19340531] - Yu-Long Li, Yanfeng Ding, Chad Agnew, Harold D Schultz. Exercise training improves peripheral chemoreflex function in heart failure rabbits.
Journal of applied physiology (Bethesda, Md. : 1985).
2008 Sep; 105(3):782-90. doi:
10.1152/japplphysiol.90533.2008. [PMID: 18583379] - David Z Levine, Michelle Iacovitti, Susan J Robertson. Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus. II. Effects of renal mass reduction.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Jun; 294(6):R1840-6. doi:
10.1152/ajpregu.00457.2007. [PMID: 18417648] - Elzbieta Kompanowska-Jezierska, Helle Wolff, Marta Kuczeriszka, Jan B Gramsbergen, Agnieszka Walkowska, Edward J Johns, Peter Bie. Renal nerves and nNOS: roles in natriuresis of acute isovolumetric sodium loading in conscious rats.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Apr; 294(4):R1130-9. doi:
10.1152/ajpregu.00908.2007. [PMID: 18234741] - Matthew E Patterson, John J Mullins, Kenneth D Mitchell. Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension.
American journal of physiology. Renal physiology.
2008 Jan; 294(1):F205-11. doi:
10.1152/ajprenal.00150.2007. [PMID: 17977909] - Lin Hong, Walter Fast. Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia.
The Journal of biological chemistry.
2007 Nov; 282(48):34684-92. doi:
10.1074/jbc.m707231200. [PMID: 17895252] - M Grzelec-Mojzesowicz, J Sadowski. Renal tissue NO and intrarenal haemodynamics during experimental variations of NO content in anaesthetised rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2007 Mar; 58(1):149-63. doi:
NULL. [PMID: 17440233] - R C Blantz, A Deng. Coordination of kidney filtration and tubular reabsorption: considerations on the regulation of metabolic demand for tubular reabsorption.
Acta physiologica Hungarica.
2007 Mar; 94(1-2):83-94. doi:
10.1556/aphysiol.94.2007.1-2.8. [PMID: 17444277] - Peter K Stricklett, Alisa K Hughes, Donald E Kohan. Endothelin-1 stimulates NO production and inhibits cAMP accumulation in rat inner medullary collecting duct through independent pathways.
American journal of physiology. Renal physiology.
2006 Jun; 290(6):F1315-9. doi:
10.1152/ajprenal.00450.2005. [PMID: 16380457] - David Z Levine, Michelle Iacovitti, Susan J Robertson, Ghadeer A Mokhtar. Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus.
American journal of physiology. Regulatory, integrative and comparative physiology.
2006 Apr; 290(4):R975-81. doi:
10.1152/ajpregu.00693.2005. [PMID: 16339386] - N M Bagnall, P C Dent, A Walkowska, J Sadowski, E J Johns. Nitric oxide inhibition and the impact on renal nerve-mediated antinatriuresis and antidiuresis in the anaesthetized rat.
The Journal of physiology.
2005 Dec; 569(Pt 3):849-56. doi:
10.1113/jphysiol.2005.097709. [PMID: 16239274] - Yu-Long Li, Yi-Fan Li, Dongmei Liu, Kurtis G Cornish, Kaushik P Patel, Irving H Zucker, Keith M Channon, Harold D Schultz. Gene transfer of neuronal nitric oxide synthase to carotid body reverses enhanced chemoreceptor function in heart failure rabbits.
Circulation research.
2005 Aug; 97(3):260-7. doi:
10.1161/01.res.0000175722.21555.55. [PMID: 15994433] - Aihua Deng, Cynthia M Miracle, Jorge M Suarez, Mark Lortie, Joseph Satriano, Scott C Thomson, Karen A Munger, Roland C Blantz. Oxygen consumption in the kidney: effects of nitric oxide synthase isoforms and angiotensin II.
Kidney international.
2005 Aug; 68(2):723-30. doi:
10.1111/j.1523-1755.2005.00450.x. [PMID: 16014049] - A Walkowska, B Badzyńska, E Kompanowska-Jezierska, E J Johns, J Sadowski. Effects of renal nerve stimulation on intrarenal blood flow in rats with intact or inactivated NO synthases.
Acta physiologica Scandinavica.
2005 Jan; 183(1):99-105. doi:
10.1111/j.1365-201x.2004.01376.x. [PMID: 15654923] - Radko Komers, Jessie N Lindsley, Terry T Oyama, Sharon Anderson. Effects of long-term inhibition of neuronal nitric oxide synthase (NOS1) in uninephrectomized diabetic rats.
Nitric oxide : biology and chemistry.
2004 Sep; 11(2):147-55. doi:
10.1016/j.niox.2004.08.005. [PMID: 15491847] - Scott C Thomson, Aihua Deng. Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback.
Kidney & blood pressure research.
2003; 26(1):10-8. doi:
10.1159/000069766. [PMID: 12697972] - Aihua Deng, John S Hammes, Scott C Thomson. Hemodynamics of early tubuloglomerular feedback resetting during reduced proximal reabsorption.
Kidney international.
2002 Dec; 62(6):2136-43. doi:
10.1046/j.1523-1755.2002.00682.x. [PMID: 12427138] - Barry Chang, Roy Mathew, Lane S Palmer, Elsa Valderrama, Howard Trachtman. Nitric oxide in obstructive uropathy: role of endothelial nitric oxide synthase.
The Journal of urology.
2002 Oct; 168(4 Pt 2):1801-4. doi:
10.1097/01.ju.0000027177.45171.e9. [PMID: 12352363] - Ivana Vanecková, Herbert J Kramer, Jan Malý, Angela Bäcker, Dirk Bokemeyer, Ludĕk Cervenka. Lack of a role of neuronal nitric oxide synthase in the regulation of the renal function in rats fed a low-sodium diet.
Kidney & blood pressure research.
2002; 25(4):224-31. doi:
10.1159/000066350. [PMID: 12424424] - L Cervenka, H J Kramer, J Malý, I Vanecková, A Bäcker, D Bokemeyer, M Bader, D Ganten, K D Mitchell. Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
Physiological research.
2002; 51(6):571-80. doi:
NULL. [PMID: 12511180] - L Cervenka, H J Kramer, J Malý, J Heller. Role of nNOS in regulation of renal function in angiotensin II-induced hypertension.
Hypertension (Dallas, Tex. : 1979).
2001 Aug; 38(2):280-5. doi:
10.1161/01.hyp.38.2.280. [PMID: 11509490] - U C Kopp, M Z Cicha, L A Smith, T Hökfelt. Nitric oxide modulates renal sensory nerve fibers by mechanisms related to substance P receptor activation.
American journal of physiology. Regulatory, integrative and comparative physiology.
2001 Jul; 281(1):R279-90. doi:
10.1152/ajpregu.2001.281.1.r279. [PMID: 11404304] - R Komers, J N Lindsley, T T Oyama, K M Allison, S Anderson. Role of neuronal nitric oxide synthase (NOS1) in the pathogenesis of renal hemodynamic changes in diabetes.
American journal of physiology. Renal physiology.
2000 Sep; 279(3):F573-83. doi:
10.1152/ajprenal.2000.279.3.f573. [PMID: 10966937] - H F Cheng, J L Wang, M Z Zhang, J A McKanna, R C Harris. Nitric oxide regulates renal cortical cyclooxygenase-2 expression.
American journal of physiology. Renal physiology.
2000 Jul; 279(1):F122-9. doi:
10.1152/ajprenal.2000.279.1.f122. [PMID: 10894794] - R Komers, T T Oyama, J G Chapman, K M Allison, S Anderson. Effects of systemic inhibition of neuronal nitric oxide synthase in diabetic rats.
Hypertension (Dallas, Tex. : 1979).
2000 Feb; 35(2):655-61. doi:
10.1161/01.hyp.35.2.655. [PMID: 10679513] - R C Harris, H Cheng, J Wang, M Zhang, J A McKanna. Interactions of the renin-angiotensin system and neuronal nitric oxide synthase in regulation of cyclooxygenase-2 in the macula densa.
Acta physiologica Scandinavica.
2000 Jan; 168(1):47-51. doi:
10.1046/j.1365-201x.2000.00642.x. [PMID: 10691779] - A Ichihara, L G Navar. Neuronal NOS contributes to biphasic autoregulatory response during enhanced TGF activity.
The American journal of physiology.
1999 07; 277(1):F113-20. doi:
10.1152/ajprenal.1999.277.1.f113. [PMID: 10409304] - A Ichihara, J D Imig, L G Navar. Neuronal nitric oxide synthase-dependent afferent arteriolar function in angiotensin II-induced hypertension.
Hypertension (Dallas, Tex. : 1979).
1999 Jan; 33(1 Pt 2):462-6. doi:
10.1161/01.hyp.33.1.462. [PMID: 9931148] - A Ichihara, J D Imig, E W Inscho, L G Navar. Cyclooxygenase-2 participates in tubular flow-dependent afferent arteriolar tone: interaction with neuronal NOS.
The American journal of physiology.
1998 10; 275(4):F605-12. doi:
10.1152/ajprenal.1998.275.4.f605. [PMID: 9755132] - A Ichihara, E W Inscho, J D Imig, L G Navar. Neuronal nitric oxide synthase modulates rat renal microvascular function.
The American journal of physiology.
1998 03; 274(3):F516-24. doi:
10.1152/ajprenal.1998.274.3.f516. [PMID: 9530268]