Quinpirole (BioDeep_00000843589)
代谢物信息卡片
Quinpirole
化学式: C13H21N3 (219.1735386)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCN1CCCC2C1CC3=C(C2)NN=C3
InChI: InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1
描述信息
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
C78272 - Agent Affecting Nervous System > C66884 - Dopamine Agonist
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:75401
- PubChem: 54562
- ChEMBL: CHEMBL240773
- MeSH: Quinpirole
- CAS: 80373-22-4
- CAS: 74196-92-2
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rodrigo Ramírez-Rodríguez, Isabel León-Sequeda, Lázaro Salomón-Lara, Daniela Perusquia-Cabrera, Deissy Herrera-Covarrubias, Lauro Fernández-Cañedo, Luis I García, Jorge Manzo, James G Pfaus, María-Leonor López-Meraz, Genaro A Coria-Avila. Enhanced D2 Agonism Induces Conditioned Appetitive Sexual Responses Toward Non-reproductive Conspecifics.
Archives of sexual behavior.
2021 11; 50(8):3901-3912. doi:
10.1007/s10508-021-02023-7. [PMID: 34665381] - Dayana Rodriguez-Contreras, Alec F Condon, David C Buck, Naeem Asad, Timothy M Dore, Dineke S Verbeek, Marina A J Tijssen, Ujwal Shinde, John T Williams, Kim A Neve. Signaling-Biased and Constitutively Active Dopamine D2 Receptor Variant.
ACS chemical neuroscience.
2021 06; 12(11):1873-1884. doi:
10.1021/acschemneuro.0c00712. [PMID: 33974399] - Hiroko Ikeda, Naomi Yonemochi, Risa Mikami, Manabu Abe, Meiko Kawamura, Rie Natsume, Kenji Sakimura, John L Waddington, Junzo Kamei. Central dopamine D2 receptors regulate plasma glucose levels in mice through autonomic nerves.
Scientific reports.
2020 12; 10(1):22347. doi:
10.1038/s41598-020-79292-0. [PMID: 33339892] - Soyon Ahn, Maya O Nesbit, Haiyan Zou, Giada Vacca, Peter Axerio-Cilies, Tran Van Sung, Anthony G Phillips. Neural bases for attenuation of morphine withdrawal by Heantos-4: role of l-tetrahydropalmatine.
Scientific reports.
2020 12; 10(1):21275. doi:
10.1038/s41598-020-78083-x. [PMID: 33277581] - Nafiseh Sadat Sanikhani, Mohammad Hossein Modarressi, Parvaneh Jafari, Nasim Vousooghi, Shilan Shafei, Mostafa Akbariqomi, Reza Heidari, Paria Sadat Lavasani, Fatemeh Yazarlou, Elahe Motevaseli, Soudeh Ghafouri-Fard. The Effect of Lactobacillus casei Consumption in Improvement of Obsessive-Compulsive Disorder: an Animal Study.
Probiotics and antimicrobial proteins.
2020 12; 12(4):1409-1419. doi:
10.1007/s12602-020-09642-x. [PMID: 32124236] - Panpan Wang, Ting Cao, Jiaojiao Chen, Yiguo Jiang, Cheng Wang, John L Waddington, Xuechu Zhen. D2 receptor-mediated miRNA-143 expression is associated with the effects of antipsychotic drugs on phencyclidine-induced schizophrenia-related locomotor hyperactivity and with Neuregulin-1 expression in mice.
Neuropharmacology.
2019 10; 157(?):107675. doi:
10.1016/j.neuropharm.2019.107675. [PMID: 31233824] - Willem J van den Brink, Robin Hartman, Dirk-Jan van den Berg, Gunnar Flik, Belén Gonzalez-Amoros, Nanda Koopman, Jeroen Elassais-Schaap, Piet Hein van der Graaf, Thomas Hankemeier, Elizabeth C M de Lange. Blood-Based Biomarkers of Quinpirole Pharmacology: Cluster-Based PK/PD and Metabolomics to Unravel the Underlying Dynamics in Rat Plasma and Brain.
CPT: pharmacometrics & systems pharmacology.
2019 02; 8(2):107-117. doi:
10.1002/psp4.12370. [PMID: 30680960] - Stijn Servaes, Dorien Glorie, Sigrid Stroobants, Steven Staelens. Neuroreceptor kinetics in rats repeatedly exposed to quinpirole as a model for OCD.
PloS one.
2019; 14(3):e0213313. doi:
10.1371/journal.pone.0213313. [PMID: 30845202] - Willem J van den Brink, Dirk-Jan van den Berg, Floor E M Bonsel, Robin Hartman, Yin-Cheong Wong, Piet H van der Graaf, Elizabeth C M de Lange. Fingerprints of CNS drug effects: a plasma neuroendocrine reflection of D2 receptor activation using multi-biomarker pharmacokinetic/pharmacodynamic modelling.
British journal of pharmacology.
2018 10; 175(19):3832-3843. doi:
10.1111/bph.14452. [PMID: 30051461] - Irene Fasciani, Ilaria Pietrantoni, Mario Rossi, Clotilde Mannoury la Cour, Gabriella Aloisi, Francesco Marampon, Marco Scarselli, Mark J Millan, Roberto Maggio. Distinctive binding properties of the negative allosteric modulator, [3H]SB269,652, at recombinant dopamine D3 receptors.
European journal of pharmacology.
2018 Jan; 819(?):181-189. doi:
10.1016/j.ejphar.2017.12.002. [PMID: 29223348] - Sarah Beggiato, Andrea Celeste Borelli, Dasiel Borroto-Escuela, Ilaria Corbucci, Maria Cristina Tomasini, Matteo Marti, Tiziana Antonelli, Sergio Tanganelli, Kjell Fuxe, Luca Ferraro. Cocaine modulates allosteric D2-σ1 receptor-receptor interactions on dopamine and glutamate nerve terminals from rat striatum.
Cellular signalling.
2017 12; 40(?):116-124. doi:
10.1016/j.cellsig.2017.09.007. [PMID: 28923416] - Meriem Gaval-Cruz, Richard B Goertz, Daniel J Puttick, Dawn E Bowles, Rebecca C Meyer, Randy A Hall, Daijin Ko, Carlos A Paladini, David Weinshenker. Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens.
Addiction biology.
2016 Jan; 21(1):35-48. doi:
10.1111/adb.12174. [PMID: 25123018] - Stefano Espinoza, Valentina Ghisi, Marco Emanuele, Damiana Leo, Ilya Sukhanov, Tatiana D Sotnikova, Evelina Chieregatti, Raul R Gainetdinov. Postsynaptic D2 dopamine receptor supersensitivity in the striatum of mice lacking TAAR1.
Neuropharmacology.
2015 Jun; 93(?):308-13. doi:
10.1016/j.neuropharm.2015.02.010. [PMID: 25721394] - Lucy G Chastain, Hongyan Qu, Chase H Bourke, P Michael Iuvone, Paul R Dobner, Charles B Nemeroff, Becky Kinkead. Striatal dopamine receptor plasticity in neurotensin deficient mice.
Behavioural brain research.
2015 Mar; 280(?):160-71. doi:
10.1016/j.bbr.2014.11.014. [PMID: 25449842] - Casey E O'Neill, Sophia C Levis, Drew C Schreiner, Jose Amat, Steven F Maier, Ryan K Bachtell. Effects of adolescent caffeine consumption on cocaine sensitivity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2015 Mar; 40(4):813-21. doi:
10.1038/npp.2014.278. [PMID: 25328052] - Ameer Y Taha, Lisa Chang, Mei Chen, Stanley I Rapoport, Epolia Ramadan. D2-like receptor activation does not initiate a brain docosahexaenoic acid signal in unanesthetized rats.
BMC neuroscience.
2014 Oct; 15(?):113. doi:
10.1186/1471-2202-15-113. [PMID: 25359512] - Yu Yang, Santiago Cuevas, Sufei Yang, Van Anthony Villar, Crisanto Escano, Laureano Asico, Peiying Yu, Xiaoliang Jiang, Edward J Weinman, Ines Armando, Pedro A Jose. Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of reactive oxygen species production.
Hypertension (Dallas, Tex. : 1979).
2014 Oct; 64(4):825-32. doi:
10.1161/hypertensionaha.114.03840. [PMID: 25024286] - Clément Vitrac, Sophie Péron, Isabelle Frappé, Pierre-Olivier Fernagut, Mohamed Jaber, Afsaneh Gaillard, Marianne Benoit-Marand. Dopamine control of pyramidal neuron activity in the primary motor cortex via D2 receptors.
Frontiers in neural circuits.
2014; 8(?):13. doi:
10.3389/fncir.2014.00013. [PMID: 24616667] - C Min, M Zheng, X Zhang, M G Caron, K M Kim. Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors.
British journal of pharmacology.
2013 Nov; 170(5):1112-29. doi:
10.1111/bph.12357. [PMID: 23992580] - Dasiel O Borroto-Escuela, Annalisa Ravani, Alexander O Tarakanov, Ismel Brito, Manuel Narvaez, Wilber Romero-Fernandez, Fidel Corrales, Luigi F Agnati, Sergio Tanganelli, Luca Ferraro, Kjell Fuxe. Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers.
Biochemical and biophysical research communications.
2013 May; 435(1):140-6. doi:
10.1016/j.bbrc.2013.04.058. [PMID: 23624386] - Thomas S Hnasko, Gregory O Hjelmstad, Howard L Fields, Robert H Edwards. Ventral tegmental area glutamate neurons: electrophysiological properties and projections.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2012 Oct; 32(43):15076-85. doi:
10.1523/jneurosci.3128-12.2012. [PMID: 23100428] - Han-Ting Chen, Nan-Yu Ruan, Jin-Chung Chen, Tzu-Yung Lin. Dopamine D2 receptor-mediated Akt/PKB signalling: initiation by the D2S receptor and role in quinpirole-induced behavioural activation.
ASN neuro.
2012 Sep; 4(6):371-82. doi:
10.1042/an20120013. [PMID: 22909302] - Yu Yang, Yanrong Zhang, Santiago Cuevas, Van Anthony Villar, Crisanto Escano, Laureano D Asico, Peiying Yu, David K Grandy, Robin A Felder, Ines Armando, Pedro A Jose. Paraoxonase 2 decreases renal reactive oxygen species production, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of NADPH oxidase.
Free radical biology & medicine.
2012 Aug; 53(3):437-46. doi:
10.1016/j.freeradbiomed.2012.05.015. [PMID: 22634053] - R Al-Hasani, J D Foster, A Metaxas, C Ledent, S M O Hourani, I Kitchen, Y Chen. Increased desensitization of dopamine D₂ receptor-mediated response in the ventral tegmental area in the absence of adenosine A(2A) receptors.
Neuroscience.
2011 Sep; 190(?):103-11. doi:
10.1016/j.neuroscience.2011.05.068. [PMID: 21669258] - Jasmin M Dao, Susan C McQuown, Sandra E Loughlin, James D Belluzzi, Frances M Leslie. Nicotine alters limbic function in adolescent rat by a 5-HT1A receptor mechanism.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2011 Jun; 36(7):1319-31. doi:
10.1038/npp.2011.8. [PMID: 21412223] - Gholamreza Fazeli, Rajaraman Gnana Oli, Nicole Schupp, Helga Stopper. The role of the dopamine transporter in dopamine-induced DNA damage.
Brain pathology (Zurich, Switzerland).
2011 May; 21(3):237-48. doi:
10.1111/j.1750-3639.2010.00440.x. [PMID: 20875051] - M Picard, S Morisset, J F Cloix, J C Bizot, M Guerin, V Beneteau, G Guillaumet, T K Hevor. Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist.
Neuroscience.
2010 Sep; 169(3):1337-46. doi:
10.1016/j.neuroscience.2010.05.040. [PMID: 20580787] - Tomonori Fujiwara, Masumi Snada, Takefumi Kofuji, Takeo Yoshikawa, Kimio Akagawa. HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems.
The European journal of neuroscience.
2010 Jul; 32(1):99-107. doi:
10.1111/j.1460-9568.2010.07269.x. [PMID: 20576034] - Y Iris Chen, Ji-Kyung Choi, Haibo Xu, Jiaqian Ren, Susan L Andersen, Bruce G Jenkins. Pharmacologic neuroimaging of the ontogeny of dopamine receptor function.
Developmental neuroscience.
2010 Jul; 32(2):125-38. doi:
10.1159/000286215. [PMID: 20523024] - Carole Deyts, Beatriz Galan-Rodriguez, Elodie Martin, Nicolas Bouveyron, Emmanuel Roze, Delphine Charvin, Jocelyne Caboche, Sandrine Bétuing. Dopamine D2 receptor stimulation potentiates PolyQ-Huntingtin-induced mouse striatal neuron dysfunctions via Rho/ROCK-II activation.
PloS one.
2009 Dec; 4(12):e8287. doi:
10.1371/journal.pone.0008287. [PMID: 20016831] - Jill H Dunham, Rebecca C Meyer, Erin L Garcia, Randy A Hall. GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions.
Biochemistry.
2009 Nov; 48(43):10286-97. doi:
10.1021/bi9013775. [PMID: 19799451] - Valentina Ghisi, Amy J Ramsey, Bernard Masri, Raul R Gainetdinov, Marc G Caron, Ali Salahpour. Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter.
Cellular signalling.
2009 Jan; 21(1):87-94. doi:
10.1016/j.cellsig.2008.09.011. [PMID: 18929645] - Spencer S Ericksen, David F Cummings, Harel Weinstein, John A Schetz. Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding.
The Journal of pharmacology and experimental therapeutics.
2009 Jan; 328(1):40-54. doi:
10.1124/jpet.108.141531. [PMID: 18849360] - Abesh K Bhattacharjee, Lisa Chang, Mei Chen, Laura White, Jane M Bell, Richard P Bazinet, Stanley I Rapoport. Chronic d-amphetamine depresses an imaging marker of arachidonic acid metabolism in rat brain.
The international journal of neuropsychopharmacology.
2008 Nov; 11(7):957-69. doi:
10.1017/s1461145708008833. [PMID: 18570702] - Rajkumar J Sevak, Wouter Koek, William Anthony Owens, Aurelio Galli, Lynette C Daws, Charles P France. Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats.
European journal of pharmacology.
2008 Sep; 592(1-3):109-15. doi:
10.1016/j.ejphar.2008.07.002. [PMID: 18652823] - Laura E Bianco, Jason Wiesinger, Christopher J Earley, Byron C Jones, John L Beard. Iron deficiency alters dopamine uptake and response to L-DOPA injection in Sprague-Dawley rats.
Journal of neurochemistry.
2008 Jul; 106(1):205-15. doi:
10.1111/j.1471-4159.2008.05358.x. [PMID: 18363828] - Ju-Heon Kim, Eun-Young Cho, Chengchun Min, Jae H Park, Kyeong-Man Kim. Characterization of functional roles of DRY motif in the 2nd intracellular loop of dopamine D2 and D3 receptors.
Archives of pharmacal research.
2008 Apr; 31(4):474-81. doi:
10.1007/s12272-001-1181-x. [PMID: 18449505] - Olaf Prante, Rainer Tietze, Carsten Hocke, Stefan Löber, Harald Hübner, Torsten Kuwert, Peter Gmeiner. Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET.
Journal of medicinal chemistry.
2008 Mar; 51(6):1800-10. doi:
10.1021/jm701375u. [PMID: 18307287] - Agustin Zapata, Bronwyn Kivell, Yang Han, Jonathan A Javitch, Elizabeth A Bolan, David Kuraguntla, Vanaja Jaligam, Murat Oz, Lankupalle D Jayanthi, Devadoss J Samuvel, Sammanda Ramamoorthy, Toni S Shippenberg. Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors.
The Journal of biological chemistry.
2007 Dec; 282(49):35842-54. doi:
10.1074/jbc.m611758200. [PMID: 17923483] - Abesh Kumar Bhattacharjee, Lindsey M Meister, Lisa Chang, Richard P Bazinet, Laura White, Stanley I Rapoport. In vivo imaging of disturbed pre- and post-synaptic dopaminergic signaling via arachidonic acid in a rat model of Parkinson's disease.
NeuroImage.
2007 Oct; 37(4):1112-21. doi:
10.1016/j.neuroimage.2007.06.012. [PMID: 17681816] - Elizabeth M Byrnes, Robert S Bridges, Victoria F Scanlan, Jessica A Babb, John J Byrnes. Sensorimotor gating and dopamine function in postpartum rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2007 May; 32(5):1021-31. doi:
10.1038/sj.npp.1301222. [PMID: 17047669] - Anthony S L Chan, Linda W C Ng, Lydia S W Poon, Winnie W Y Chan, Yung H Wong. Dopaminergic and adrenergic toxicities on SK-N-MC human neuroblastoma cells are mediated through G protein signaling and oxidative stress.
Apoptosis : an international journal on programmed cell death.
2007 Jan; 12(1):167-79. doi:
10.1007/s10495-006-0524-8. [PMID: 17136323] - Marketa Marvanova, Charles D Nichols. Identification of neuroprotective compounds of caenorhabditis elegans dopaminergic neurons against 6-OHDA.
Journal of molecular neuroscience : MN.
2007; 31(2):127-37. doi:
10.1385/jmn/31:02:127. [PMID: 17478886] - Guyu Ho, Yuren Wang, Philip G Jones, Kathleen H Young. Activation of serum response element by D2 dopamine receptor is governed by Gbetagamma-mediated MAPK and Rho pathways and regulated by RGS proteins.
Pharmacology.
2007; 79(2):114-21. doi:
10.1159/000098097. [PMID: 17179741] - Keith Chiasson, Benoît Daoust, Daniel Levesque, Maria-Grazia Martinoli. Dopamine D2 agonists, bromocriptine and quinpirole, increase MPP+ -induced toxicity in PC12 cells.
Neurotoxicity research.
2006 Aug; 10(1):31-42. doi:
10.1007/bf03033332. [PMID: 17000468] - Mireille Basselin, Lisa Chang, Stanley I Rapoport. Chronic lithium chloride administration to rats elevates glucose metabolism in wide areas of brain, while potentiating negative effects on metabolism of dopamine D2-like receptor stimulation.
Psychopharmacology.
2006 Aug; 187(3):303-11. doi:
10.1007/s00213-006-0425-0. [PMID: 16786332] - Benjamin J Copeland, Norton H Neff, Maria Hadjiconstantinou. Enhanced dopamine uptake in the striatum following repeated restraint stress.
Synapse (New York, N.Y.).
2005 Sep; 57(3):167-74. doi:
10.1002/syn.20169. [PMID: 15945060] - Abesh Kumar Bhattacharjee, Lisa Chang, Ho-Joo Lee, Richard P Bazinet, Ruth Seemann, Stanley I Rapoport. D2 but not D1 dopamine receptor stimulation augments brain signaling involving arachidonic acid in unanesthetized rats.
Psychopharmacology.
2005 Aug; 180(4):735-42. doi:
10.1007/s00213-005-2208-4. [PMID: 16163535] - Mireille Basselin, Lisa Chang, Jane M Bell, Stanley I Rapoport. Chronic lithium chloride administration to unanesthetized rats attenuates brain dopamine D2-like receptor-initiated signaling via arachidonic acid.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2005 Jun; 30(6):1064-75. doi:
10.1038/sj.npp.1300671. [PMID: 15812572] - Chunhe Wang, David C Buck, Rui Yang, Tara A Macey, Kim A Neve. Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases.
Journal of neurochemistry.
2005 May; 93(4):899-909. doi:
10.1111/j.1471-4159.2005.03055.x. [PMID: 15857393] - Shengwei Zou, Lei Li, Lin Pei, Brian Vukusic, Hubert H M Van Tol, Frank J S Lee, Qi Wan, Fang Liu. Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2005 Apr; 25(17):4385-95. doi:
10.1523/jneurosci.5099-04.2005. [PMID: 15858065] - Desa Bacic, Paola Capuano, Michel Baum, Jianning Zhang, Gerti Stange, Jürg Biber, Brigitte Kaissling, Orson W Moe, Carsten A Wagner, Heini Murer. Activation of dopamine D1-like receptors induces acute internalization of the renal Na+/phosphate cotransporter NaPi-IIa in mouse kidney and OK cells.
American journal of physiology. Renal physiology.
2005 Apr; 288(4):F740-7. doi:
10.1152/ajprenal.00380.2004. [PMID: 15547113] - Matthew S Goldberg, Antonio Pisani, Marian Haburcak, Timothy A Vortherms, Tohru Kitada, Cinzia Costa, Youren Tong, Giuseppina Martella, Anne Tscherter, Andrea Martins, Giorgio Bernardi, Bryan L Roth, Emmanuel N Pothos, Paolo Calabresi, Jie Shen. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1.
Neuron.
2005 Feb; 45(4):489-96. doi:
10.1016/j.neuron.2005.01.041. [PMID: 15721235] - Julie Broadbent, Kathryn M Kampmueller, Sharon A Koonse. Role of dopamine in behavioral sensitization to ethanol in DBA/2J mice.
Alcohol (Fayetteville, N.Y.).
2005 Feb; 35(2):137-48. doi:
10.1016/j.alcohol.2005.03.006. [PMID: 15963427] - Colin Davidson, Tong H Lee, Everett H Ellinwood. Acute and chronic continuous methamphetamine have different long-term behavioral and neurochemical consequences.
Neurochemistry international.
2005 Feb; 46(3):189-203. doi:
10.1016/j.neuint.2004.11.004. [PMID: 15670635] - Timothy A Vortherms, Chau H Nguyen, Catherine H Berlot, Val J Watts. Using molecular tools to dissect the role of Galphas in sensitization of AC1.
Molecular pharmacology.
2004 Dec; 66(6):1617-24. doi:
10.1124/mol.104.000166. [PMID: 15361543] - Yusuke Takeuchi, Kohji Fukunaga. Dopamine D2 receptor activates extracellular signal-regulated kinase through the specific region in the third cytoplasmic loop.
Journal of neurochemistry.
2004 Jun; 89(6):1498-507. doi:
10.1111/j.1471-4159.2004.02446.x. [PMID: 15189353] - Yuren Wang, Kathleen H Young. Analysis of RGSZ1 protein interaction with Galphai subunits.
Methods in enzymology.
2004; 390(?):31-52. doi:
10.1016/s0076-6879(04)90003-1. [PMID: 15488169] - Atsushi Ueda, Ryoji Ozono, Tetsuya Oshima, Ai Yano, Masayuki Kambe, Yasuhiro Teranishi, Motoya Katsuki, Kazuaki Chayama. Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice.
American journal of hypertension.
2003 Oct; 16(10):853-8. doi:
10.1016/s0895-7061(03)01013-6. [PMID: 14553965] - D Stanic, C L Parish, W M Zhu, E V Krstew, A J Lawrence, J Drago, D I Finkelstein, M K Horne. Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc.
Journal of neurochemistry.
2003 Jul; 86(2):329-43. doi:
10.1046/j.1471-4159.2003.01843.x. [PMID: 12871574] - Jyoti Patel, Katrin A Mooslehner, Pok Man Chan, Piers C Emson, Jonathan A Stamford. Presynaptic control of striatal dopamine neurotransmission in adult vesicular monoamine transporter 2 (VMAT2) mutant mice.
Journal of neurochemistry.
2003 May; 85(4):898-910. doi:
10.1046/j.1471-4159.2003.01732.x. [PMID: 12716422] - Gerd Luippold, Alexander Max, Margitta Albinus, Hartmut Osswald, Bernd Mühlbauer. Role of the renin-angiotensin system in the compensation of quinpirole-induced blood pressure decrease.
Naunyn-Schmiedeberg's archives of pharmacology.
2003 May; 367(5):427-33. doi:
10.1007/s00210-003-0740-5. [PMID: 12709781] - Geraldine B Sacca, Daniel A Sáenz, Carolina O Jaliffa, Luciana Minces, María I Keller Sarmiento, Ruth E Rosenstein. Photic regulation of heme oxygenase activity in the golden hamster retina: involvement of dopamine.
Journal of neurochemistry.
2003 Apr; 85(2):534-42. doi:
10.1046/j.1471-4159.2003.01697.x. [PMID: 12675930] - N F Nichols, M G Cimini, J V Haas, B A Staton, J Tedroff, K A Svensson. PNU-96391A (OSU6162) antagonizes the development of behavioral sensitization induced by dopamine agonists in a rat model for Parkinson's disease.
Neuropharmacology.
2002 Oct; 43(5):817-24. doi:
10.1016/s0028-3908(02)00144-2. [PMID: 12384167] - Jeffrey M Brown, Evan L Riddle, Verónica Sandoval, Raul K Weston, Jarom E Hanson, Michael J Crosby, Yvette V Ugarte, James W Gibb, Glen R Hanson, Annette E Fleckenstein. A single methamphetamine administration rapidly decreases vesicular dopamine uptake.
The Journal of pharmacology and experimental therapeutics.
2002 Aug; 302(2):497-501. doi:
10.1124/jpet.302.2.497. [PMID: 12130707] - K Lemmer, G Ahnert-Hilger, M Höpfner, S Hoegerle, S Faiss, P Grabowski, M Jockers-Scherübl, E O Riecken, M Zeitz, H Scherübl. Expression of dopamine receptors and transporter in neuroendocrine gastrointestinal tumor cells.
Life sciences.
2002 Jun; 71(6):667-78. doi:
10.1016/s0024-3205(02)01703-4. [PMID: 12072155] - Aldo Badiani, Rosa Vaccaro, Rosetta Burdino, Arianna Casini, Pacifico Valeri, Tindaro G Renda, Paolo Nencini. Dissociation in the effects of the D2/D3 dopaminergic agonist quinpirole on drinking and on vasopressin levels in the rat.
Neuroscience letters.
2002 Jun; 325(2):79-82. doi:
10.1016/s0304-3940(02)00261-6. [PMID: 12044626] - Michael H Baumann, Jennifer M Phillips, Mario A Ayestas, Syed F Ali, Kenner C Rice, Richard B Rothman. Preclinical evaluation of GBR12909 decanoate as a long-acting medication for methamphetamine dependence.
Annals of the New York Academy of Sciences.
2002 Jun; 965(?):92-108. doi:
10.1111/j.1749-6632.2002.tb04154.x. [PMID: 12105088] - M G Cumbay, V J Watts. Heterologous sensitization of recombinant adenylate cyclases by activation of D(2) dopamine receptors.
The Journal of pharmacology and experimental therapeutics.
2001 Jun; 297(3):1201-9. doi:
NULL. [PMID: 11356947] - J Gomeza, L Zhang, E Kostenis, C C Felder, F P Bymaster, J Brodkin, H Shannon, B Xia, A Duttaroy, C X Deng, J Wess. Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice.
Life sciences.
2001 Apr; 68(22-23):2457-66. doi:
10.1016/s0024-3205(01)01039-6. [PMID: 11392613] - T L Thompson, S R Bridges, W J Weirs. Alteration of dopamine transport in the striatum and nucleus accumbens of ovariectomized and estrogen-primed rats following N-(p-isothiocyanatophenethyl) spiperone (NIPS) treatment.
Brain research bulletin.
2001 Apr; 54(6):631-8. doi:
10.1016/s0361-9230(01)00472-5. [PMID: 11403989] - E M Byrnes, J J Byrnes, R S Bridges. Increased sensitivity of dopamine systems following reproductive experience in rats.
Pharmacology, biochemistry, and behavior.
2001 Mar; 68(3):481-9. doi:
10.1016/s0091-3057(01)00449-x. [PMID: 11325402] - X Zhuang, R S Oosting, S R Jones, R R Gainetdinov, G W Miller, M G Caron, R Hen. Hyperactivity and impaired response habituation in hyperdopaminergic mice.
Proceedings of the National Academy of Sciences of the United States of America.
2001 Feb; 98(4):1982-7. doi:
10.1073/pnas.98.4.1982. [PMID: 11172062] - L A van Vliet, N Rodenhuis, H Wikström, T A Pugsley, K A Serpa, L T Meltzer, T G Heffner, L D Wise, M E Lajiness, R M Huff, K Svensson, G R Haenen, A Bast. Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists.
Journal of medicinal chemistry.
2000 Sep; 43(19):3549-57. doi:
10.1021/jm000087z. [PMID: 11000009] - M Scarselli, M Armogida, S Chiacchio, M G DeMontis, A Colzi, G U Corsini, R Maggio. Reconstitution of functional dopamine D(2s) receptor by co-expression of amino- and carboxyl-terminal receptor fragments.
European journal of pharmacology.
2000 Jun; 397(2-3):291-6. doi:
10.1016/s0014-2999(00)00272-7. [PMID: 10844126] - K Pietilä, L Ahtee. Chronic nicotine administration in the drinking water affects the striatal dopamine in mice.
Pharmacology, biochemistry, and behavior.
2000 May; 66(1):95-103. doi:
10.1016/s0091-3057(00)00235-5. [PMID: 10837848] - P S D'Aquila, M Collu, P Devoto, G Serra. Chronic lithium chloride fails to prevent imipramine-induced sensitization to the dopamine D(2)-like receptor agonist quinpirole.
European journal of pharmacology.
2000 Apr; 395(2):157-60. doi:
10.1016/s0014-2999(00)00189-8. [PMID: 10794822] - S A Treseder, M Jackson, P Jenner. The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.
British journal of pharmacology.
2000 Apr; 129(7):1355-64. doi:
10.1038/sj.bjp.0703189. [PMID: 10742291] - M van den Buuse, G A Head. Quinpirole treatment increases renal sympathetic nerve activity and baroreflex gain in conscious rabbits: a spectral study.
European journal of pharmacology.
2000 Jan; 388(1):85-8. doi:
10.1016/s0014-2999(99)00835-3. [PMID: 10657550] - P G Zaworski, G L Alberts, J F Pregenzer, W B Im, J L Slightom, G S Gill. Efficient functional coupling of the human D3 dopamine receptor to G(o) subtype of G proteins in SH-SY5Y cells.
British journal of pharmacology.
1999 Nov; 128(6):1181-8. doi:
10.1038/sj.bjp.0702905. [PMID: 10578130] - J Gomeza, L Zhang, E Kostenis, C Felder, F Bymaster, J Brodkin, H Shannon, B Xia, C Deng, J Wess. Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America.
1999 Aug; 96(18):10483-8. doi:
10.1073/pnas.96.18.10483. [PMID: 10468635] - G R King, Z Xiong, S Douglas, T H Lee, E H Ellinwood. The effects of continuous cocaine dose on the induction of behavioral tolerance and dopamine autoreceptor function.
European journal of pharmacology.
1999 Jul; 376(3):207-15. doi:
10.1016/s0014-2999(99)00385-4. [PMID: 10448878] - S R Jones, R R Gainetdinov, X T Hu, D C Cooper, R M Wightman, F J White, M G Caron. Loss of autoreceptor functions in mice lacking the dopamine transporter.
Nature neuroscience.
1999 Jul; 2(7):649-55. doi:
10.1038/10204. [PMID: 10404198] - M Dudkowska, M Manteuffel-Cymborowska, W Chmurzyńska, B Grzelakowska-Sztabert. Catecholamines participate in the induction of ornithine decarboxylase gene expression in normal and hyperplastic mouse kidney.
Biochimica et biophysica acta.
1999 May; 1454(1):71-9. doi:
10.1016/s0925-4439(99)00028-9. [PMID: 10354516] - B S Neal-Beliveau, J N Joyce. Timing: A critical determinant of the functional consequences of neonatal 6-OHDA lesions.
Neurotoxicology and teratology.
1999 Mar; 21(2):129-40. doi:
10.1016/s0892-0362(98)00044-0. [PMID: 10192273] - M Batchelor, J O Schenk. Protein kinase A activity may kinetically upregulate the striatal transporter for dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1998 Dec; 18(24):10304-9. doi:
10.1523/jneurosci.18-24-10304.1998. [PMID: 9852568] - S Ikemoto, N E Goeders. Microinjections of dopamine agonists and cocaine elevate plasma corticosterone: dissociation effects among the ventral and dorsal striatum and medial prefrontal cortex.
Brain research.
1998 Dec; 814(1-2):171-8. doi:
10.1016/s0006-8993(98)01070-1. [PMID: 9838097] - M Baum, R Quigley. Inhibition of proximal convoluted tubule transport by dopamine.
Kidney international.
1998 Nov; 54(5):1593-600. doi:
10.1046/j.1523-1755.1998.00156.x. [PMID: 9844135] - S Izenwasser, J B Acri, P M Kunko, T Shippenberg. Repeated treatment with the selective kappa opioid agonist U-69593 produces a marked depletion of dopamine D2 receptors.
Synapse (New York, N.Y.).
1998 Nov; 30(3):275-83. doi:
10.1002/(sici)1098-2396(199811)30:3<275::aid-syn5>3.0.co;2-8. [PMID: 9776131] - M van den Buuse, S B Tritton, S L Burke, G A Head. Interaction of the dopamine D2 receptor agonist quinpirole with sympathetic vasomotor tone and the central action of rilmenidine in conscious rabbits.
Journal of the autonomic nervous system.
1998 Oct; 72(2-3):187-94. doi:
10.1016/s0165-1838(98)00104-0. [PMID: 9851568] - G Luippold, B Mühlbauer. Dopamine D2 receptors mediate glomerular hyperfiltration due to amino acids.
The Journal of pharmacology and experimental therapeutics.
1998 Sep; 286(3):1248-52. doi:
NULL. [PMID: 9732385] - D V Coscina, P J Currie, H Szechtman. Association of altered whole-body metabolism with locomotor sensitization induced by quinpirole.
Physiology & behavior.
1998 Mar; 63(5):755-61. doi:
10.1016/s0031-9384(97)00531-3. [PMID: 9617996] - S W Robinson, M G Caron. Selective inhibition of adenylyl cyclase type V by the dopamine D3 receptor.
Molecular pharmacology.
1997 Sep; 52(3):508-14. doi:
10.1124/mol.52.3.508. [PMID: 9281614] - M K Ho, Y H Wong. Functional role of amino-terminal serine16 and serine27 of G alphaZ in receptor and effector coupling.
Journal of neurochemistry.
1997 Jun; 68(6):2514-22. doi:
10.1046/j.1471-4159.1997.68062514.x. [PMID: 9166747] - H Sanada, L Yao, P A Jose, R M Carey, R A Felder. Dopamine D3 receptors in rat juxtaglomerular cells.
Clinical and experimental hypertension (New York, N.Y. : 1993).
1997 Jan; 19(1-2):93-105. doi:
10.3109/10641969709080807. [PMID: 9028638] - K Y Little, J Gorebig, F I Carroll, J Mapili, J H Meador-Woodruff. Lack of dopamine receptor agonists effect on striatal dopamine transporter binding sites.
Brain research.
1996 Dec; 742(1-2):313-6. doi:
10.1016/s0006-8993(96)01033-5. [PMID: 9117410] - S Patel, S Patel, R Marwood, F Emms, D Marston, P D Leeson, N R Curtis, J J Kulagowski, S B Freedman. Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor.
Molecular pharmacology.
1996 Dec; 50(6):1658-64. doi:
NULL. [PMID: 8967990] - J M Thomas, B B Hoffman. Isoform-specific sensitization of adenylyl cyclase activity by prior activation of inhibitory receptors: role of beta gamma subunits in transducing enhanced activity of the type VI isoform.
Molecular pharmacology.
1996 May; 49(5):907-14. doi:
NULL. [PMID: 8622641] - C Missale, F Boroni, S Sigala, A Buriani, M Fabris, A Leon, R Dal Toso, P Spano. Nerve growth factor in the anterior pituitary: localization in mammotroph cells and cosecretion with prolactin by a dopamine-regulated mechanism.
Proceedings of the National Academy of Sciences of the United States of America.
1996 Apr; 93(9):4240-5. doi:
10.1073/pnas.93.9.4240. [PMID: 8633048]