lyso-Sulfatide (NH4+salt) (BioDeep_00000843463)
代谢物信息卡片
化学式: C24H47NO10S (541.2920522000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCC=CC(C(COC1C(C(C(C(O1)CO)O)OS(=O)(=O)O)O)N)O
InChI: InChI=1S/C24H47NO10S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-33-24-22(29)23(35-36(30,31)32)21(28)20(16-26)34-24/h14-15,18-24,26-29H,2-13,16-17,25H2,1H3,(H,30,31,32)/b15-14+
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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BioCyc(0)
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Plant Reactome(0)
INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mina Mirzaian, Gertjan Kramer, Ben J H M Poorthuis. Quantification of sulfatides and lysosulfatides in tissues and body fluids by liquid chromatography-tandem mass spectrometry.
Journal of lipid research.
2015 Apr; 56(4):936-43. doi:
10.1194/jlr.m057232. [PMID: 25632048] - Subramanian Yegneswaran, Yajnavalka Banerjee, José A Fernández, Hiroshi Deguchi, John H Griffin. Lyso-Sulfatide Binds Factor Xa and Inhibits Thrombin Generation by the Prothrombinase Complex.
PloS one.
2015; 10(8):e0135025. doi:
10.1371/journal.pone.0135025. [PMID: 26263376] - Maria Blomqvist, Volkmar Gieselmann, Jan-Eric Månsson. Accumulation of lysosulfatide in the brain of arylsulfatase A-deficient mice.
Lipids in health and disease.
2011 Feb; 10(?):28. doi:
10.1186/1476-511x-10-28. [PMID: 21299873] - Gang Li, Rui Hu, Yuji Kamijo, Takero Nakajima, Toshifumi Aoyama, Teruo Inoue, Koichi Node, Reiji Kannagi, Mamoru Kyogashima, Atsushi Hara. Establishment of a quantitative, qualitative, and high-throughput analysis of sulfatides from small amounts of sera by matrix-assisted laser desorption ionization-time of flight mass spectrometry.
Analytical biochemistry.
2007 Mar; 362(1):1-7. doi:
10.1016/j.ab.2006.12.024. [PMID: 17254536] - Dirk M Zajonc, Igor Maricic, Douglass Wu, Ramesh Halder, Keshab Roy, Chi-Huey Wong, Vipin Kumar, Ian A Wilson. Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity.
The Journal of experimental medicine.
2005 Dec; 202(11):1517-26. doi:
10.1084/jem.20051625. [PMID: 16314439] - J R Nofer, B Levkau, I Wolinska, R Junker, M Fobker, A von Eckardstein, U Seedorf, G Assmann. Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids.
The Journal of biological chemistry.
2001 Sep; 276(37):34480-5. doi:
10.1074/jbc.m103782200. [PMID: 11432865] - J R Nofer, M Fobker, G Höbbel, R Voss, I Wolinska, M Tepel, W Zidek, R Junker, U Seedorf, A von Eckardstein, G Assmann, M Walter. Activation of phosphatidylinositol-specific phospholipase C by HDL-associated lysosphingolipid. Involvement in mitogenesis but not in cholesterol efflux.
Biochemistry.
2000 Dec; 39(49):15199-207. doi:
10.1021/bi001162a. [PMID: 11106499] - T Kanazawa, S Nakamura, M Momoi, T Yamaji, H Takematsu, H Yano, H Sabe, A Yamamoto, T Kawasaki, Y Kozutsumi. Inhibition of cytokinesis by a lipid metabolite, psychosine.
The Journal of cell biology.
2000 May; 149(4):943-50. doi:
10.1083/jcb.149.4.943. [PMID: 10811833] - E Sugiyama, A Hara, K Uemura. A quantitative analysis of serum sulfatide by matrix-assisted laser desorption ionization time-of-flight mass spectrometry with delayed ion extraction.
Analytical biochemistry.
1999 Oct; 274(1):90-7. doi:
10.1006/abio.1999.4245. [PMID: 10527500] - K Toda, T Kobayashi, I Goto, K Ohno, Y Eto, K Inui, S Okada. Lysosulfatide (sulfogalactosylsphingosine) accumulation in tissues from patients with metachromatic leukodystrophy.
Journal of neurochemistry.
1990 Nov; 55(5):1585-91. doi:
10.1111/j.1471-4159.1990.tb04942.x. [PMID: 1976756] - E Sugiyama, K Uemura, A Hara, T Taketomi. Effects of various lysosphingolipids on cell growth, morphology and lipid composition in three neuroblastoma cell lines.
Biochemical and biophysical research communications.
1990 Jun; 169(2):673-9. doi:
10.1016/0006-291x(90)90383-x. [PMID: 2357225] - T Taketomi, A Hara, Y Kutsukake, E Sugiyama. New approach for characterization of lysosulfatide by TLC, fast atom bombardment mass spectrometry and NMR spectroscopy.
Journal of biochemistry.
1990 May; 107(5):680-4. doi:
10.1093/oxfordjournals.jbchem.a123107. [PMID: 2398033] - B Rosengren, P Fredman, J E Månsson, L Svennerholm. Lysosulfatide (galactosylsphingosine-3-O-sulfate) from metachromatic leukodystrophy and normal human brain.
Journal of neurochemistry.
1989 Apr; 52(4):1035-41. doi:
10.1111/j.1471-4159.1989.tb01844.x. [PMID: 2926387] - K Toda, T Kobayashi, I Goto, T Kurokawa, K Ogomori. Accumulation of lysosulfatide (sulfogalactosylsphingosine) in tissues of a boy with metachromatic leukodystrophy.
Biochemical and biophysical research communications.
1989 Mar; 159(2):605-11. doi:
10.1016/0006-291x(89)90037-5. [PMID: 2539117]