5-(3-Fluoropropyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]benzamide (BioDeep_00000843407)
代谢物信息卡片
5-(3-Fluoropropyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]benzamide
化学式: C20H29FN2O3 (364.2162)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC(=CC(=C1OC)C(=O)NCC2CCCN2CC=C)CCCF
InChI: InChI=1S/C20H29FN2O3/c1-4-10-23-11-6-8-16(23)14-22-20(24)17-12-15(7-5-9-21)13-18(25-2)19(17)26-3/h4,12-13,16H,1,5-11,14H2,2-3H3,(H,22,24)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Mohammed N Tantawy, Todd E Peterson, Carrie K Jones, Kari Johnson, Jerri M Rook, P Jeffrey Conn, Ronald M Baldwin, M Sib Ansari, Robert M Kessler. Impact of isoflurane anesthesia on D2 receptor occupancy by [18F]fallypride measured by microPET with a modified Logan plot.
Synapse (New York, N.Y.).
2011 Nov; 65(11):1173-80. doi:
10.1002/syn.20955. [PMID: 21584868] - Natalia del Campo, Roger J Tait, Julio Acosta-Cabronero, Young T Hong, David Izquierdo-Garcia, Rob Smith, Franklin I Aigbirhio, Barbara J Sahakian, Ulrich Müller, Trevor W Robbins, Tim D Fryer. Quantification of receptor-ligand binding potential in sub-striatal domains using probabilistic and template regions of interest.
NeuroImage.
2011 Mar; 55(1):101-12. doi:
10.1016/j.neuroimage.2010.11.071. [PMID: 21126591] - Georg Nikisch, Pierre Baumann, Bernhard Kiessling, Michael Reinert, Georg Wiedemann, Jan Kehr, Aleksander A Mathé, Markus Piel, Frank Roesch, Heike Weisser, Peter Schneider, Andreas Hertel. Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine.
Journal of psychiatric research.
2010 Sep; 44(12):754-9. doi:
10.1016/j.jpsychires.2010.02.004. [PMID: 20176367] - Ingo Vernaleken, Hildegard Janouschek, Mardjan Raptis, Sandra Hellmann, Tanja Veselinovic, Anno Bröcheler, Christian Boy, Paul Cumming, Christoph Hiemke, Frank Rösch, Wolfgang M Schäfer, Gerhard Gründer. Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas.
The international journal of neuropsychopharmacology.
2010 Aug; 13(7):951-60. doi:
10.1017/s1461145710000374. [PMID: 20392299] - Mark Slifstein, Lawrence S Kegeles, Xiaoyan Xu, Judy L Thompson, Nina Urban, John Castrillon, Elizabeth Hackett, S-A Bae, Marc Laruelle, Anissa Abi-Dargham. Striatal and extrastriatal dopamine release measured with PET and [(18)F] fallypride.
Synapse (New York, N.Y.).
2010 May; 64(5):350-62. doi:
10.1002/syn.20734. [PMID: 20029833] - Nicholas T Vandehey, Jeffrey M Moirano, Alexander K Converse, James E Holden, Jogesh Mukherjee, Dhanabalan Murali, R Jerry Nickles, Richard J Davidson, Mary L Schneider, Bradley T Christian. High-affinity dopamine D2/D3 PET radioligands 18F-fallypride and 11C-FLB457: a comparison of kinetics in extrastriatal regions using a multiple-injection protocol.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2010 May; 30(5):994-1007. doi:
10.1038/jcbfm.2009.270. [PMID: 20040928] - Ingo Vernaleken, Christine Fellows, Hildegard Janouschek, Anno Bröcheler, Tanja Veselinovic, Christian Landvogt, Christian Boy, Hans-Georg Buchholz, Katja Spreckelmeyer, Peter Bartenstein, Paul Cumming, Christoph Hiemke, Frank Rösch, Wolfgang Schäfer, Dean F Wong, Gerhard Gründer. Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone).
Journal of clinical psychopharmacology.
2008 Dec; 28(6):608-17. doi:
10.1097/jcp.0b013e31818ba2f6. [PMID: 19011428] - Gerhard Gründer, Christine Fellows, Hildegard Janouschek, Tanja Veselinovic, Christian Boy, Anno Bröcheler, Katrin M Kirschbaum, Sandra Hellmann, Katja M Spreckelmeyer, Christoph Hiemke, Frank Rösch, Wolfgang M Schaefer, Ingo Vernaleken. Brain and plasma pharmacokinetics of aripiprazole in patients with schizophrenia: an [18F]fallypride PET study.
The American journal of psychiatry.
2008 Aug; 165(8):988-95. doi:
10.1176/appi.ajp.2008.07101574. [PMID: 18381901] - Gerhard Gründer, Christian Landvogt, Ingo Vernaleken, Hans-Georg Buchholz, Jasmin Ondracek, Thomas Siessmeier, Sebastian Härtter, Mathias Schreckenberger, Peter Stoeter, Christoph Hiemke, Frank Rösch, Dean F Wong, Peter Bartenstein. The striatal and extrastriatal D2/D3 receptor-binding profile of clozapine in patients with schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2006 May; 31(5):1027-35. doi:
10.1038/sj.npp.1300931. [PMID: 16237387] - Jogeshwar Mukherjee, Bradley T Christian, Kelly A Dunigan, Bingzhi Shi, Tanjore K Narayanan, Martin Satter, Joseph Mantil. Brain imaging of 18F-fallypride in normal volunteers: blood analysis, distribution, test-retest studies, and preliminary assessment of sensitivity to aging effects on dopamine D-2/D-3 receptors.
Synapse (New York, N.Y.).
2002 Dec; 46(3):170-88. doi:
10.1002/syn.10128. [PMID: 12325044]
