[11-[4,5-Dihydroxy-6-methyl-3-(methylamino)oxan-2-yl]oxy-4-(2-oxo-1,3-dioxolan-4-yl)-5-oxatricyclo[8.3.0.04,6]tridec-1(13)-en-2,7-diyn-12-yl] 2-hydroxy-7-methoxy-5-methylnaphthalene-1-carboxylate (BioDeep_00000843111)
代谢物信息卡片
[11-[4,5-Dihydroxy-6-methyl-3-(methylamino)oxan-2-yl]oxy-4-(2-oxo-1,3-dioxolan-4-yl)-5-oxatricyclo[8.3.0.04,6]tridec-1(13)-en-2,7-diyn-12-yl] 2-hydroxy-7-methoxy-5-methylnaphthalene-1-carboxylate
化学式: C35H35NO12 (661.2159)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(C(C(O1)OC2C3CC#CC4C(O4)(C#CC3=CC2OC(=O)C5=C(C=CC6=C5C=C(C=C6C)OC)O)C7COC(=O)O7)NC)O)O
InChI: InChI=1S/C35H35NO12/c1-16-12-19(42-4)14-22-20(16)8-9-23(37)27(22)32(40)45-24-13-18-10-11-35(26-15-43-34(41)46-26)25(48-35)7-5-6-21(18)31(24)47-33-28(36-3)30(39)29(38)17(2)44-33/h8-9,12-14,17,21,24-26,28-31,33,36-39H,6,15H2,1-4H3
描述信息
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors
D009676 - Noxae > D003603 - Cytotoxins
D000970 - Antineoplastic Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Shun Umeda, Keiichi Ito, Eiji Takahashi, Fumihiro Kimura, Makoto Sumitomo, Tatsumi Kaji, Masamichi Hayakawa, Tomohiko Asano. [Clinical experience of treatment of liver metastasis of renal cell carcinoma treated with SMANCS/Lipiodol therapy].
Hinyokika kiyo. Acta urologica Japonica.
2010 Oct; 56(10):543-9. doi:
NULL. [PMID: 21063157] - Parameswaran Hariharan, Christopher Gunasekaran Sudhahar, Shan-Ho Chou, Der-Hang Chin. Lipid bilayer-assisted release of an enediyne antibiotic from neocarzinostatin chromoprotein.
Biochemistry.
2010 Sep; 49(35):7722-32. doi:
10.1021/bi100735v. [PMID: 20712297] - Akinori Nagamitsu, Khaled Greish, Hiroshi Maeda. Elevating blood pressure as a strategy to increase tumor-targeted delivery of macromolecular drug SMANCS: cases of advanced solid tumors.
Japanese journal of clinical oncology.
2009 Nov; 39(11):756-66. doi:
10.1093/jjco/hyp074. [PMID: 19596662] - Yoshihisa Tomioka, Shigeki Kisara, Saki Yoshizawa, Mika Ozawa, Naoto Suzuki, Hiroaki Yamaguchi, Takanori Hishinuma, Michinao Mizugaki, Junichi Goto. Preparation of neocarzinostatin apoprotein mutants and the randomized library on the chromophore-binding cavity.
Biological & pharmaceutical bulletin.
2006 May; 29(5):1010-4. doi:
10.1248/bpb.29.1010. [PMID: 16651736] - Orit Fingrut, Dorit Reischer, Ronit Rotem, Natalia Goldin, Irit Altboum, Israel Zan-Bar, Eliezer Flescher. Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells.
British journal of pharmacology.
2005 Nov; 146(6):800-8. doi:
10.1038/sj.bjp.0706394. [PMID: 16170329] - Hiroshi Ishii, Junji Furuse, Michitaka Nagase, Yasushi Maru, Masahiro Yoshino, Takayuki Hayashi. A phase I study of hepatic arterial infusion chemotherapy with zinostatin stimalamer alone for hepatocellular carcinoma.
Japanese journal of clinical oncology.
2003 Nov; 33(11):570-3. doi:
10.1093/jjco/hyg106. [PMID: 14711981] - Eigo Otsuji, Hiroshi Tsuruta, Atsushi Toma, Shinichiro Kobayashi, Kazuma Okamoto, Yoshihiro Yata, Hisakazu Yamagishi. Effects of idiotypic human anti-mouse antibody against in vitro binding and antitumor activity of a monoclonal antibody-drug conjugate.
Hepato-gastroenterology.
2003 Mar; 50(50):380-4. doi:
NULL. [PMID: 12749227] - Yoshihiro Yata, Eigo Otsuji, Kazuma Okamoto, Hiroshi Tsuruta, Shinichiro Kobayashi, Atsushi Toma, Hisahazu Yamagishi. Decreased production of anti-mouse antibody after administration of human/mouse chimeric monoclonal antibody-neocarzinostatin conjugate to human.
Hepato-gastroenterology.
2003 Jan; 50(49):80-4. doi:
NULL. [PMID: 12629996] - H Maeda. SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy.
Advanced drug delivery reviews.
2001 Mar; 46(1-3):169-85. doi:
10.1016/s0169-409x(00)00134-4. [PMID: 11259839] - K Tsuchiya, T Uchida, M Kobayashi, H Maeda, T Konno, H Yamanaka. Tumor-targeted chemotherapy with SMANCS in lipiodol for renal cell carcinoma: longer survival with larger size tumors.
Urology.
2000 Apr; 55(4):495-500. doi:
10.1016/s0090-4295(99)00537-3. [PMID: 10736490] - S Tsunoda, Y Tsutsumi, S Nakagawa, T Mayumi. [Targeting therapy using a monoclonal antibody against tumor vascular endothelium].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2000 Mar; 120(3):256-64. doi:
10.1248/yakushi1947.120.3_256. [PMID: 10723267] - N F Schor, Y Y Tyurina, J P Fabisiak, V A Tyurin, J S Lazo, V E Kagan. Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosis.
Brain research.
1999 Jun; 831(1-2):125-30. doi:
10.1016/s0006-8993(99)01414-6. [PMID: 10411991] - K Yamada, T Sato, A Yamada, S Tanaka, S Fujii, R Matuo, K Murata, T Manabe, J Oda. [A case of hepatocellular carcinoma with tumor thrombus in the right atrium successfully treated by arterial administration of lipiodol-SMANCS].
Gan to kagaku ryoho. Cancer & chemotherapy.
1999 Feb; 26(3):361-4. doi:
NULL. [PMID: 10065101] - M Kimura, T Konno, Y Miyamoto, Y Kojima, H Maeda. Intracavitary administration: pharmacokinetic advantages of macromolecular anticancer agents against peritoneal and pleural carcinomatoses.
Anticancer research.
1998 Jul; 18(4A):2547-50. doi:
NULL. [PMID: 9703908] - T Okusaka, S Okada, H Ishii, M Ikeda, H Nakasuka, H Nagahama, R Iwata, H Furukawa, K Takayasu, Y Nakanishi, M Sakamoto, S Hirohashi, M Yoshimori. Transarterial chemotherapy with zinostatin stimalamer for hepatocellular carcinoma.
Oncology.
1998 Jul; 55(4):276-83. doi:
10.1159/000011863. [PMID: 9663415] - K Miura, N Nakao, A Yoshimoto, T Yamano, J Inoue, Y Takayasu. [Arterial infusion of SMANCS-Lipiodol for advanced hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy.
1998 Feb; 25 Suppl 1(?):51-5. doi:
NULL. [PMID: 9512688] - T Ihaya, M Ametani, E Matsusue. [Transcatheter arterial embolization with SMANCS and epiADM for hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy.
1998 Feb; 25 Suppl 1(?):109-15. doi:
NULL. [PMID: 9512698] - M Yoshikawa, M Ebara, H Fukuda, N Sugiura, H Saisho. [Repeated arterial infusion of zinostatin stimalamer using port for advanced hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy.
1998 Feb; 25 Suppl 1(?):30-3. doi:
NULL. [PMID: 9512684] - H Maeda. [Recent advances in research on SMANCS].
Gan to kagaku ryoho. Cancer & chemotherapy.
1998 Feb; 25 Suppl 1(?):1-9. doi:
". [PMID: 9512680] - T Shimizu, H Endou. [SMANCS/TAE for hepatocellular carcinoma: comparison with SMANCS/TAI].
Gan to kagaku ryoho. Cancer & chemotherapy.
1998 Feb; 25 Suppl 1(?):80-3. doi:
NULL. [PMID: 9512693] - H Nakaba, T Hashimoto, S Sunada, D Akamatsu, A Ito, S Teramoto, S Ohara, S Katayama. [Results of SMANCS/Lipiodol injection therapy for multiple intrahepatic recurrence of hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy.
1998 Feb; 25 Suppl 1(?):46-50. doi:
NULL. [PMID: 9512687] - E Otsuji, T Yamaguchi, K Yamamoto, H Matsumura, H Tsuruta, Y Yata, H Nishi, K Okamoto, K Kitamura, T Takahashi. Decreased renal accumulation of biotinylated chimeric monoclonal antibody-neocarzinostatin conjugate after administration of avidin.
Japanese journal of cancer research : Gann.
1997 Feb; 88(2):205-12. doi:
10.1111/j.1349-7006.1997.tb00367.x. [PMID: 9119750] - T Konno, T Oda, A Nagamitsu, K Tabaru, R Yamashita, Y Kai. [Targeted chemotherapy of hepatocellular carcinoma using Lipiodol as a carrier].
Gan to kagaku ryoho. Cancer & chemotherapy.
1996 Sep; 23(11):1392-9. doi:
NULL. [PMID: 8854762] - E Otsuji, T Yamaguchi, H Matsumura, K Yamamoto, H Tsuruta, Y Yata, H Nishi, K Okamoto, K Kitamura, T Takahashi. Distribution of neocarzinostatin conjugated to biotinylated chimeric monoclonal antibody Fab fragments after administration of avidin.
British journal of cancer.
1996 Aug; 74(4):597-602. doi:
10.1038/bjc.1996.407. [PMID: 8761376] - M Fukushima, T Fukutomi, Y Tanabe, K Hiroshige, K Yoshida. [A successful treatment using SMANCS-TAE for hepatocellular carcinoma with tumor thrombus in the portal trunk].
Gan to kagaku ryoho. Cancer & chemotherapy.
1996 Jul; 23(8):1073-6. doi:
NULL. [PMID: 8687225] - T Kato, K Sato, H Kakinuma. [Targeting therapy for renal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
1994 May; 21(6):772-6. doi:
NULL. [PMID: 8185334] - H Okumura, S Nakamura, S Ohtake, T Yoshida, K Kobayashi, Y Okabe, S Matano, K Kyohda, T Matsuda. Hemolytic uremic syndrome developing during remission of acute myelomonocytic leukemia.
American journal of hematology.
1993 Sep; 44(1):66-7. doi:
10.1002/ajh.2830440115. [PMID: 8342567] - T Takahashi, T Yamaguchi, K Kitamura, A Noguchi, M Honda, E Otsuji. Follow-up study of patients treated with monoclonal antibody-drug conjugate: report of 77 cases with colorectal cancer.
Japanese journal of cancer research : Gann.
1993 Sep; 84(9):976-81. doi:
10.1111/j.1349-7006.1993.tb00188.x. [PMID: 8407566] - K Mihara, T Hojo, M Fujikawa, Y Takakura, H Sezaki, M Hashida. Disposition characteristics of protein drugs in the perfused rat kidney.
Pharmaceutical research.
1993 Jun; 10(6):823-7. doi:
10.1023/a:1018996808153. [PMID: 8321849] - C J Li, Y Miyamoto, Y Kojima, H Maeda. Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure.
British journal of cancer.
1993 May; 67(5):975-80. doi:
10.1038/bjc.1993.179. [PMID: 8494731] - T Oda, T Konno, N Ohtsuka, M Kimura, R Mizumachi. [Antitumor activities of oily suspended zinostatin stimalamer (YM 881) against VX2 carcinoma implanted in the liver of rabbits--comparison with another anticancer agent].
Gan to kagaku ryoho. Cancer & chemotherapy.
1991 Nov; 18(14):2423-8. doi:
". [PMID: 1835341] - K Takashina, K Kitamura, T Yamaguchi, A Noguchi, A Noguchi, H Tsurumi, T Takahashi. Comparative pharmacokinetic properties of murine monoclonal antibody A7 modified with neocarzinostatin, dextran and polyethylene glycol.
Japanese journal of cancer research : Gann.
1991 Oct; 82(10):1145-50. doi:
10.1111/j.1349-7006.1991.tb01769.x. [PMID: 1720116] - U Gottschalk, M C Garnett, R K Ward, A Maibücher, W Köhnlein. Increased serum stability and prolonged biological half-life of neocarzinostatin covalently bound to monoclonal antibodies.
The Journal of antibiotics.
1991 Oct; 44(10):1148-54. doi:
10.7164/antibiotics.44.1148. [PMID: 1835456] - T Toge, K Jinushi, A Sawamura, K Matsuki. [Study on the intra-tumor tissue concentration of zinostatin stimalamer in the liver following intra-arterial injection of zinostatin stimalamer (YM881) suspension].
Gan to kagaku ryoho. Cancer & chemotherapy.
1991 Aug; 18(10):1677-80. doi:
NULL. [PMID: 1651687] - Y Miyamoto, H Maeda. Enhancement by verapamil of neocarzinostatin action on multidrug-resistant Chinese hamster ovary cells: possible release of nonprotein chromophore in cells.
Japanese journal of cancer research : Gann.
1991 Mar; 82(3):351-6. doi:
10.1111/j.1349-7006.1991.tb01853.x. [PMID: 1673676] - M Kobayashi, K Imai, S Sugihara, H Maeda, T Konno, H Yamanaka. Tumor-targeted chemotherapy with lipid contrast medium and macromolecular anticancer drug (SMANCS) for renal cell carcinoma.
Urology.
1991 Mar; 37(3):288-94. doi:
10.1016/0090-4295(91)80308-t. [PMID: 1848030] - N Harata, T Sasaki, H Osaki, T Saito, S Shibata, T Muryoi, O Takai, K Yoshinaga. Therapeutic treatment of New Zealand mouse disease by a limited number of anti-idiotypic antibodies conjugated with neocarzinostatin.
The Journal of clinical investigation.
1990 Sep; 86(3):769-76. doi:
10.1172/jci114773. [PMID: 2144300] - M Honda, T Yamaguchi, E Ohtsuji, A Noguchi, Y Chimori, M Doi, M Kamiguchi, A Noguchi, K Kitamura, T Yokota. [Immunoresponses and efficacy after arterial infusion of immunoconjugate A7-NCS in patients with colon cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
1990 Aug; 17(8 Pt 2):1811-4. doi:
NULL. [PMID: 2143891] - F Suzuki, R B Pollard, S Uchimura, T Munakata, H Maeda. Role of natural killer cells and macrophages in the nonspecific resistance to tumors in mice stimulated with SMANCS, a polymer-conjugated derivative of neocarzinostatin.
Cancer research.
1990 Jul; 50(13):3897-904. doi:
NULL. [PMID: 2141295] - S Noda, S Konno, J Tanaka, M Yamada, N Yoshitake. Treatment of renal cell carcinoma with intra-arterial administration of SMANCS dissolved in Lipiodol.
Anticancer research.
1990 May; 10(3):709-15. doi:
NULL. [PMID: 2164351] - Y Kohgo, H Kondo, J Kato, K Sasaki, N Tsushima, T Nishisato, M Hirayama, K Fujikawa, N Shintani, Y Mogi. Kinetics of internalization and cytotoxicity of transferrin-neocarzinostatin conjugate in human leukemia cell line, K562.
Japanese journal of cancer research : Gann.
1990 Jan; 81(1):91-9. doi:
10.1111/j.1349-7006.1990.tb02512.x. [PMID: 2139019] - H Taniguchi, T Takahashi, T Yamaguchi, K Sawai. Intraarterial infusion chemotherapy for metastatic liver tumors using multiple anti-cancer agents suspended in a lipid contrast medium.
Cancer.
1989 Nov; 64(10):2001-6. doi:
10.1002/1097-0142(19891115)64:10<2001::aid-cncr2820641005>3.0.co;2-s. [PMID: 2553236] - H Maeda. [Principle and therapeutic effect of lipophilic anticancer agent [SMANCS/lipiodol]: selective targeting with oily contrast medium].
Gan to kagaku ryoho. Cancer & chemotherapy.
1989 Oct; 16(10):3323-31. doi:
NULL. [PMID: 2552930] - T Otsuka, Y Matsukado, S Uemura, J Kuratsu, H Sonoda, Y Mihara, S Goto. [Pharmacokinetics of neocarzinostatin in patients with malignant glioma. Quantitative analysis of tissue concentration].
Neurologia medico-chirurgica.
1989 Jun; 29(6):471-5. doi:
10.2176/nmc.29.471. [PMID: 2479848] - I Satake, K Tari, F Ohwada, T Saitoh, T Negishi. Prophylactic effects of perioperatively administered neocarzinostatin in renal cell carcinoma.
Nihon Gan Chiryo Gakkai shi.
1989 Apr; 24(4):809-16. doi:
NULL. [PMID: 2528598] - F Suzuki, R B Pollard, H Maeda. Stimulation of non-specific resistance to tumors in the mouse using a poly(maleic-acid-styrene)-conjugated neocarzinostatin.
Cancer immunology, immunotherapy : CII.
1989; 30(2):97-104. doi:
10.1007/bf01665960. [PMID: 2480846] - K Tari, I Satake, S Kojima, T Tsujii, J Yonese. [Neocarzinostatin therapy of advanced renal cell carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy.
1988 Sep; 15(9):2719-23. doi:
NULL. [PMID: 2970825] - H Taniguchi, Y Shioaki, A Itoh, K Seiki, M Shimotsuma, T Yamaguchi, K Sawai, T Takahashi, S Kitai, Y Shimamura. [Trans-arterial embolization or transarterial infusion of anti-cancer drugs suspended in a lipid contrast medium against unresectable metastatic liver cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
1988 Aug; 15(8 Pt 2):2568-72. doi:
". [PMID: 2843125] - T Konno, H Maeda. [Targeting cancer chemotherapy using lipiodol as a carrier of anticancer drugs for hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy.
1988 Apr; 15(4 Pt 2-1):1043-50. doi:
NULL. [PMID: 2839112] - N Ohtsuka, T Konno. [Arterial administration of oily anticancer agents dissolved in lipiodol fluid in recurrence of hepatoma after hepatic resection and in metastatic liver cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
1988 Apr; 15(4 Pt 2-2):1351-8. doi:
NULL. [PMID: 2837992] - Y Kohgo, J Kato, K Sasaki, H Kondo. [Targeting chemotherapy with transferrin-neocarzinostatin conjugate].
Gan to kagaku ryoho. Cancer & chemotherapy.
1988 Apr; 15(4 Pt 2-1):1072-6. doi:
NULL. [PMID: 2968779] - F Suzuki, T Munakata, H Maeda. Interferon induction by SMANCS: a polymer-conjugated derivative of neocarzinostatin.
Anticancer research.
1988 Jan; 8(1):97-103. doi:
. [PMID: 2451896] - T Suzuki, M Kobayashi, T Nakamura, O Takahashi, K Imai, H Yamanaka, K Suzuki, T Konno, H Maeda. [Histological effect of SMANCS/LPD therapy in renal cell carcinoma].
Nihon Gan Chiryo Gakkai shi.
1987 Oct; 22(9):2210-7. doi:
NULL. [PMID: 2833546] - A Satomi, Y Takada, K Ishida. [Experimental study of intralymphatic chemotherapy in rabbits].
Gan to kagaku ryoho. Cancer & chemotherapy.
1987 Jul; 14(7):2262-8. doi:
NULL. [PMID: 2955746] - K Yamasaki, T Konno, Y Miyauchi, H Maeda. [Prevention of hepatic metastases in rabbits by administration of an oily anticancer agent into the portal vein].
Gan to kagaku ryoho. Cancer & chemotherapy.
1987 May; 14(5 Pt 1):1224-8. doi:
NULL. [PMID: 3034169] - Y Matsumura, T Oda, H Maeda. [General mechanism of intratumor accumulation of macromolecules: advantage of macromolecular therapeutics].
Gan to kagaku ryoho. Cancer & chemotherapy.
1987 Mar; 14(3 Pt 2):821-9. doi:
NULL. [PMID: 2952066] - T Konno. [Targeting chemotherapy of hepatocellular carcinoma by arterial administration of anticancer agents dissolved in lipiodol].
Gan to kagaku ryoho. Cancer & chemotherapy.
1987 Feb; 14(2):373-80. doi:
NULL. [PMID: 3028275] - Y Matsumura, H Maeda. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.
Cancer research.
1986 Dec; 46(12 Pt 1):6387-92. doi:
NULL. [PMID: 2946403] - J E Grimwade, T A Beerman. Measurement of bleomycin, neocarzinostatin, and auromomycin cleavage of cell-free and intracellular simian virus 40 DNA and chromatin.
Molecular pharmacology.
1986 Oct; 30(4):358-63. doi:
NULL. [PMID: 2429169] - E Ouchi, I Honnda, A Wakui, K Kikuchi, N Ishida. [The effects of neocarzinostatin on superoxide production by monocyte-derived macrophages].
Gan no rinsho. Japan journal of cancer clinics.
1986 Apr; 32(4):387-91. doi:
NULL. [PMID: 3012141] - S Maki, T Konno, K Iwai, S Tashiro, N Otsuka, K Yamasaki, J Mizutani, Y Miyauchi, H Maeda, I Yokoyama. [CT image of the liver cancer after administration of SMANCS/lipiodol].
Gan to kagaku ryoho. Cancer & chemotherapy.
1986 Apr; 13(4 Pt 2):1603-10. doi:
. [PMID: 3015036] - S Hirayama, F Sato, T Oda, H Maeda. [Stability of high molecular weight anticancer agent SMANCS and its transfer from oil-phase to water-phase. Comparative study with neocarzinostatin].
The Japanese journal of antibiotics.
1986 Mar; 39(3):815-22. doi:
". [PMID: 3016359] - T Oda, T Morinaga, H Maeda. Stimulation of macrophage by polyanions and its conjugated proteins and effect on cell membrane.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1986 Jan; 181(1):9-17. doi:
10.3181/00379727-181-42218. [PMID: 2935880] - R Ishida, T Takahashi, T Nishimoto. Chromosomes of G2 arrested cells are easily analyzed by use of the 'tsBN2' mutation.
Cell structure and function.
1985 Dec; 10(4):417-20. doi:
10.1247/csf.10.417. [PMID: 2935262] - S Maki, T Konno, H Maeda. Image enhancement in computerized tomography for sensitive diagnosis of liver cancer and semiquantitation of tumor selective drug targeting with oily contrast medium.
Cancer.
1985 Aug; 56(4):751-7. doi:
10.1002/1097-0142(19850815)56:4<751::aid-cncr2820560409>3.0.co;2-y. [PMID: 3160453] - H Maeda, T Konno. [Tumor-targeted chemotherapy with lipid contrast medium and macro molecular anticancer agents theoretical considerations and clinical outcome].
Gan to kagaku ryoho. Cancer & chemotherapy.
1985 Mar; 12(3 Pt 2):773-82. doi:
NULL. [PMID: 2985005] - I Satake, K Tari, M Yamamoto, H Nishimura. Neocarzinostatin-induced complete regression of metastatic renal cell carcinoma.
The Journal of urology.
1985 Jan; 133(1):87-9. doi:
10.1016/s0022-5347(17)48799-4. [PMID: 3155476] - S Konno, J Tanaka, D Urabe, F Miyazaki, S Noda, H Maeda, T Konno. [Treatment of malignant renal tumor with intra-arterial administration of oily anticancer drugs].
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.
1984 Dec; 75(12):1874-82. doi:
10.5980/jpnjurol1928.75.12_1874. [PMID: 6100120] - T Konno, H Maeda, K Iwai, S Maki, S Tashiro, M Uchida, Y Miyauchi. Selective targeting of anti-cancer drug and simultaneous image enhancement in solid tumors by arterially administered lipid contrast medium.
Cancer.
1984 Dec; 54(11):2367-74. doi:
10.1002/1097-0142(19841201)54:11<2367::aid-cncr2820541111>3.0.co;2-f. [PMID: 6093980] - K Iwai, H Maeda, T Konno. Use of oily contrast medium for selective drug targeting to tumor: enhanced therapeutic effect and X-ray image.
Cancer research.
1984 May; 44(5):2115-21. doi:
NULL. [PMID: 6324996] - H Maeda, T Konno, K Iwai, S Maki, S Tashiro. [Tumor selective drug delivery with lipid contrast medium (smancs/lipiodol): sustained antitumor effect, enhanced diagnostic value and quantification of dosage regimen].
Gan to kagaku ryoho. Cancer & chemotherapy.
1984 Apr; 11(4):814-26. doi:
". [PMID: 6326681] - T Konno, H Maeda, K Iwai, S Tashiro, S Maki, T Morinaga, M Mochinaga, T Hiraoka, I Yokoyama. Effect of arterial administration of high-molecular-weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma: a preliminary report.
European journal of cancer & clinical oncology.
1983 Aug; 19(8):1053-65. doi:
10.1016/0277-5379(83)90028-7. [PMID: 6311559] - S W Hall, J Knight, A Broughton, R S Benjamin, E McKelvey. Clinical pharmacology of the anticancer polypeptide neocarzinostatin.
Cancer chemotherapy and pharmacology.
1983; 10(3):200-4. doi:
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Gan to kagaku ryoho. Cancer & chemotherapy.
1982 Nov; 9(11):2005-15. doi:
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Gan to kagaku ryoho. Cancer & chemotherapy.
1982 Jul; 9(6):1040-5. doi:
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Gan to kagaku ryoho. Cancer & chemotherapy.
1982 May; 9(5):898-905. doi:
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1982 Apr; 73(2):278-84. doi:
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Journal of pharmacobio-dynamics.
1981 Oct; 4(10):812-9. doi:
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Cancer chemotherapy and pharmacology.
1981; 5(4):243-9. doi:
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Biochemistry.
1980 Oct; 19(21):4786-90. doi:
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Cancer research.
1979 Mar; 39(3):757-61. doi:
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Cancer treatment reports.
1978 Dec; 62(12):2063-70. doi:
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Clinical chemistry.
1978 Dec; 24(12):2139-44. doi:
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1978; 63(?):252-60. doi:
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Antimicrobial agents and chemotherapy.
1977 Jun; 11(6):941-5. doi:
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Cancer research.
1976 Dec; 36(12):4378-81. doi:
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European journal of cancer.
1976 Nov; 12(11):865-70. doi:
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1976; 33(5-6):265-70. doi:
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1975 Oct; 66(5):523-7. doi:
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