p-(3-(p-Fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl)benzonitrile (BioDeep_00000843035)

   


代谢物信息卡片


p-(3-(p-Fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl)benzonitrile

化学式: C18H15FN4O (322.12298319999996)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1CC(C(C2=CC=C(C=C2)C#N)N3C=NC=N3)O)F
InChI: InChI=1S/C18H15FN4O/c19-16-7-3-13(4-8-16)9-17(24)18(23-12-21-11-22-23)15-5-1-14(10-20)2-6-15/h1-8,11-12,17-18,24H,9H2

描述信息

同义名列表

1 个代谢物同义名

p-(3-(p-Fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl)benzonitrile



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  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • L Lindh, H Lindeberg, A Banting, S Banting, S Sainmaa, S Beasley, H T Korhonen, O A T Peltoniemi. Administration of aromatase inhibitor MPV-2213ad to blue fox vixens (Vulpes lagopus) as a model for contraception in female dogs. Theriogenology. 2020 Aug; 152(?):53-63. doi: 10.1016/j.theriogenology.2020.04.009. [PMID: 32380275]
  • Xiangdong Li, Leena Strauss, Sari Mäkelä, Tomi Streng, Ilpo Huhtaniemi, Risto Santti, Matti Poutanen. Multiple structural and functional abnormalities in the p450 aromatase expressing transgenic male mice are ameliorated by a p450 aromatase inhibitor. The American journal of pathology. 2004 Mar; 164(3):1039-48. doi: 10.1016/s0002-9440(10)63191-4. [PMID: 14982857]
  • Tomi Streng, Mari Lehtoranta, Matti Poutanen, Antti Talo, Risto Lammintausta, Risto Santti. Developmental, estrogen induced infravesical obstruction is reversible in adult male rodents. The Journal of urology. 2002 Nov; 168(5):2263-8. doi: 10.1097/01.ju.0000034141.56909.27. [PMID: 12394772]
  • Xiangdong Li, Anni Wärri, Sari Mäkelä, Tommi Ahonen, Tomi Streng, Risto Santti, Matti Poutanen. Mammary gland development in transgenic male mice expressing human P450 aromatase. Endocrinology. 2002 Oct; 143(10):4074-83. doi: 10.1210/en.2002-220181. [PMID: 12239119]
  • O Ahokoski, K Irjala, M Taalikka, P Manninen, K Halonen, L Kangas, E Salminen, R Huupponen, H Scheinin. Pharmacokinetics of finrozole (MPV-2213ad), a novel selective aromatase inhibitor, in healthy men. British journal of clinical pharmacology. 2001 Dec; 52(6):702-4. doi: 10.1046/j.0306-5251.2001.01488.x. [PMID: 11736883]
  • V Luukkaa, J Rouru, O Ahokoski, H Scheinin, K Irjala, R Huupponen. Acute inhibition of oestrogen biosynthesis does not affect serum leptin levels in young men. European journal of endocrinology. 2000 Feb; 142(2):164-9. doi: 10.1530/eje.0.1420164. [PMID: 10664525]
  • O Ahokoski, K Irjala, S Huhtala, E Salminen, H Scheinin, R Huupponen. A double-blind study of MPV-2213ad, a novel aromatase inhibitor, in healthy male subjects. European journal of clinical pharmacology. 1999 Mar; 55(1):27-34. doi: 10.1007/s002280050588. [PMID: 10206081]
  • O Ahokoski, K Irjala, R Huupponen, K Halonen, E Salminen, H Scheinin. Hormonal effects of MPV-2213ad, a new selective aromatase inhibitor, in healthy male subjects. A phase I study. British journal of clinical pharmacology. 1998 Feb; 45(2):141-6. doi: 10.1046/j.1365-2125.1998.00654.x. [PMID: 9491826]