Thiazole, 4,5-dihydro-2,4,4-trimethyl- (BioDeep_00000842850)
代谢物信息卡片
Thiazole, 4,5-dihydro-2,4,4-trimethyl-
化学式: C6H11NS (129.0612166)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=NC(CS1)(C)C
InChI: InChI=1S/C6H11NS/c1-5-7-6(2,3)4-8-5/h4H2,1-3H3
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Melanie S Kessler, Sébastien Debilly, Stephanie Schöppenthau, Thomas Bielser, Andreas Bruns, Basil Künnecke, Markus von Kienlin, Joseph G Wettstein, Jean-Luc Moreau, Céline Risterucci. fMRI fingerprint of unconditioned fear-like behavior in rats exposed to trimethylthiazoline.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2012 Mar; 22(3):222-30. doi:
10.1016/j.euroneuro.2011.07.011. [PMID: 21856130] - Teodor G Păunescu, Steven Rodriguez, Eric Benz, Mary McKee, Robert Tyszkowski, Mark W Albers, Dennis Brown. Loss of the V-ATPase B1 subunit isoform expressed in non-neuronal cells of the mouse olfactory epithelium impairs olfactory function.
PloS one.
2012; 7(9):e45395. doi:
10.1371/journal.pone.0045395. [PMID: 23028982] - S V Sotnikov, P O Markt, A E Umriukhin, R Landgraf. Genetic predisposition to anxiety-related behavior predicts predator odor response.
Behavioural brain research.
2011 Nov; 225(1):230-4. doi:
10.1016/j.bbr.2011.07.022. [PMID: 21801755] - Christopher J Fitzpatrick, Dayan Knox, Israel Liberzon. Inactivation of the prelimbic cortex enhances freezing induced by trimethylthiazoline, a component of fox feces.
Behavioural brain research.
2011 Aug; 221(1):320-3. doi:
10.1016/j.bbr.2011.03.024. [PMID: 21420435] - Marcelo Febo, Ashley S Pira. Increased BOLD activation to predator stressor in subiculum and midbrain of amphetamine-sensitized maternal rats.
Brain research.
2011 Mar; 1382(?):118-27. doi:
10.1016/j.brainres.2010.11.092. [PMID: 21134359] - Kelly S Sink, David L Walker, Yong Yang, Michael Davis. Calcitonin gene-related peptide in the bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior and increases neural activation in anxiety-related structures.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2011 Feb; 31(5):1802-10. doi:
10.1523/jneurosci.5274-10.2011. [PMID: 21289190] - Harry Pantazopoulos, Hamid Dolatshad, Fred C Davis. A fear-inducing odor alters PER2 and c-Fos expression in brain regions involved in fear memory.
PloS one.
2011; 6(5):e20658. doi:
10.1371/journal.pone.0020658. [PMID: 21655193] - Christine H Kapelewski, Jeanette M Bennett, Sonia A Cavigelli, Laura C Klein. Application of a naturalistic psychogenic stressor in periadolescent mice: effect on serum corticosterone levels differs by strain but not sex.
BMC research notes.
2010 Jun; 3(?):170. doi:
10.1186/1756-0500-3-170. [PMID: 20565762] - Romain Hacquemand, Laurence Jacquot, Gérard Brand. Comparative Fear-Related Behaviors to Predator Odors (TMT and Natural Fox Feces) before and after Intranasal ZnSO(4) Treatment in Mice.
Frontiers in behavioral neuroscience.
2010; 4(?):188. doi:
10.3389/fnbeh.2010.00188. [PMID: 21206761] - Jerome H Pagani, Jeffrey B Rosen. The medial hypothalamic defensive circuit and 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) induced fear: comparison of electrolytic and neurotoxic lesions.
Brain research.
2009 Aug; 1286(?):133-46. doi:
10.1016/j.brainres.2009.06.062. [PMID: 19559688] - Jeffrey B Rosen, Jerome H Pagani, Katherine L G Rolla, Cameron Davis. Analysis of behavioral constraints and the neuroanatomy of fear to the predator odor trimethylthiazoline: a model for animal phobias.
Neuroscience and biobehavioral reviews.
2008 Sep; 32(7):1267-76. doi:
10.1016/j.neubiorev.2008.05.006. [PMID: 18619675] - L G Staples, I S McGregor, R Apfelbach, G E Hunt. Cat odor, but not trimethylthiazoline (fox odor), activates accessory olfactory and defense-related brain regions in rats.
Neuroscience.
2008 Feb; 151(4):937-47. doi:
10.1016/j.neuroscience.2007.11.039. [PMID: 18201833] - Thomas Endres, Markus Fendt. Conditioned behavioral responses to a context paired with the predator odor trimethylthiazoline.
Behavioral neuroscience.
2007 Jun; 121(3):594-601. doi:
10.1037/0735-7044.121.3.594. [PMID: 17592951] - Jaspreet S Kambo, Liisa A M Galea. Activational levels of androgens influence risk assessment behaviour but do not influence stress-induced suppression in hippocampal cell proliferation in adult male rats.
Behavioural brain research.
2006 Dec; 175(2):263-70. doi:
10.1016/j.bbr.2006.08.032. [PMID: 17028002] - Francis X Brennan, Kevin D Beck, Richard J Servatius. Predator odor exposure facilitates acquisition of a leverpress avoidance response in rats.
Neuropsychiatric disease and treatment.
2006 Mar; 2(1):65-9. doi:
NULL. [PMID: 19412447] - Stephen M Siviy, Kelly A Harrison, Iain S McGregor. Fear, risk assessment, and playfulness in the juvenile rat.
Behavioral neuroscience.
2006 Feb; 120(1):49-59. doi:
10.1037/0735-7044.120.1.49. [PMID: 16492116] - Thomas Endres, Raimund Apfelbach, Markus Fendt. Behavioral changes induced in rats by exposure to trimethylthiazoline, a component of fox odor.
Behavioral neuroscience.
2005 Aug; 119(4):1004-10. doi:
10.1037/0735-7044.119.4.1004. [PMID: 16187828] - Elizabeth A Myers, Linda Rinaman. Trimethylthiazoline supports conditioned flavor avoidance and activates viscerosensory, hypothalamic, and limbic circuits in rats.
American journal of physiology. Regulatory, integrative and comparative physiology.
2005 Jun; 288(6):R1716-26. doi:
10.1152/ajpregu.00479.2004. [PMID: 15661969] - Markus Fendt, Thomas Endres, Catherine A Lowry, Raimund Apfelbach, Iain S McGregor. TMT-induced autonomic and behavioral changes and the neural basis of its processing.
Neuroscience and biobehavioral reviews.
2005; 29(8):1145-56. doi:
10.1016/j.neubiorev.2005.04.018. [PMID: 16099043] - Lorey K Takahashi, Brandy R Nakashima, Hyechong Hong, Kendra Watanabe. The smell of danger: a behavioral and neural analysis of predator odor-induced fear.
Neuroscience and biobehavioral reviews.
2005; 29(8):1157-67. doi:
10.1016/j.neubiorev.2005.04.008. [PMID: 16095694] - D Caroline Blanchard, Guy Griebel, Robert J Blanchard. Conditioning and residual emotionality effects of predator stimuli: some reflections on stress and emotion.
Progress in neuro-psychopharmacology & biological psychiatry.
2003 Dec; 27(8):1177-85. doi:
10.1016/j.pnpbp.2003.09.012. [PMID: 14659473] - Markus Fendt, Thomas Endres, Raimund Apfelbach. Temporary inactivation of the bed nucleus of the stria terminalis but not of the amygdala blocks freezing induced by trimethylthiazoline, a component of fox feces.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2003 Jan; 23(1):23-8. doi:
10.1523/jneurosci.23-01-00023.2003. [PMID: 12514197] - P Tanapat, N B Hastings, T A Rydel, L A Galea, E Gould. Exposure to fox odor inhibits cell proliferation in the hippocampus of adult rats via an adrenal hormone-dependent mechanism.
The Journal of comparative neurology.
2001 Sep; 437(4):496-504. doi:
10.1002/cne.1297. [PMID: 11503148]