manassantin B (BioDeep_00000842815)

描述信息

Manassantin B is a lignan isolated from Saururus cernuus and Saururus chinensis and has been shown to exhibit antineoplastic activity. It has a role as a metabolite and an antineoplastic agent. It is a dimethoxybenzene, a member of benzodioxoles, a lignan, a member of oxolanes and a secondary alcohol.

Manassantin B is a natural coumarin derivative that has been identified for its various biological functions, particularly in the context of cancer research and antiviral therapy. Its key biological roles include:

Antitumor Activity: Manassantin B has shown potential in inhibiting the growth of cancer cells. It may interfere with signaling pathways that are crucial for tumor cell proliferation and survival, although the exact mechanisms are still under investigation.
Antiviral Properties: This compound has demonstrated effectiveness against certain viruses, possibly by inhibiting viral replication or modulating the host’s immune response to the infection.

Manassantin B could help in starving tumors of their blood supply.
Modulation of Apoptosis: It may induce apoptosis, which is programmed cell death, in cancer cells. This is a mechanism by which the body eliminates unwanted or damaged cells, including cancerous ones.
Inhibition of Kinases: Some studies suggest that Manassantin B can inhibit kinases, which are enzymes that play a role in cell signaling and are often overactive in cancer.
It’s important to note that while Manassantin B shows promise in laboratory settings, its efficacy and safety in clinical settings are still being researched. The compound’s precise mechanisms of action and its potential as a therapeutic agent require further investigation.

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