7,12-Dihydroxymethylbenz(a)anthracene (BioDeep_00000842732)
代谢物信息卡片
7,12-Dihydroxymethylbenz(a)anthracene
化学式: C20H16O2 (288.1150236)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C=CC3=C(C4=CC=CC=C4C(=C32)CO)CO
InChI: InChI=1S/C20H16O2/c21-11-18-15-7-3-4-8-16(15)19(12-22)20-14-6-2-1-5-13(14)9-10-17(18)20/h1-10,21-22H,11-12H2
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wen-Chen Wang, Ching-Yi Chen, Hseng-Kuang Hsu, Li-Min Lin, Yuk-Kwan Chen. Chemopreventive effect of Toona sinensis leaf extract on 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch squamous cell carcinogenesis.
Archives of oral biology.
2016 Oct; 70(?):130-142. doi:
10.1016/j.archoralbio.2016.06.015. [PMID: 27348052] - Deepalakshmi Krishnamoorthy, Mirunalini Sankaran. Modulatory effect of Pleurotus ostreatus on oxidant/antioxidant status in 7, 12-dimethylbenz (a) anthracene induced mammary carcinoma in experimental rats--A dose-response study.
Journal of cancer research and therapeutics.
2016 Jan; 12(1):386-94. doi:
10.4103/0973-1482.148691. [PMID: 27072268] - Arivazhagan Lakshmi, Sorimuthu Pillai Subramanian. Tangeretin ameliorates oxidative stress in the renal tissues of rats with experimental breast cancer induced by 7,12-dimethylbenz[a]anthracene.
Toxicology letters.
2014 Sep; 229(2):333-48. doi:
10.1016/j.toxlet.2014.06.845. [PMID: 24995432] - Jehan A Khan, Jalaluddin A Jalal, C Ioanndes, Said S Moselhy. Evaluation of the in vitro antimutagenic effect of Doash tea aqueous extracts.
Toxicology and industrial health.
2012 Aug; 28(7):593-604. doi:
10.1177/0748233711416952. [PMID: 21996713] - Ramadass Nandhakumar, Kombiyil Salini, Sivasithambaram Niranjali Devaraj. Morin augments anticarcinogenic and antiproliferative efficacy against 7,12-dimethylbenz(a)-anthracene induced experimental mammary carcinogenesis.
Molecular and cellular biochemistry.
2012 May; 364(1-2):79-92. doi:
10.1007/s11010-011-1207-5. [PMID: 22350814] - Jin-A Lee, Bock-Gie Jung, Bong-Joo Lee. Inhibitory effects of Opuntia humifusa on 7, 12-dimethyl- benz[a]anthracene and 12-O-tetradecanoylphorbol-13- acetate induced two-stage skin carcinogenesis.
Asian Pacific journal of cancer prevention : APJCP.
2012; 13(9):4655-60. doi:
10.7314/apjcp.2012.13.9.4655. [PMID: 23167397] - Piengchai Kupradinun, Anong Tepsuwan, Nopsaran Tantasi, Nuntana Meesiripun, Anudep Rungsipipat, Wannee R Kusamran. Anticlastogenic and anticarcinogenic potential of Thai bitter gourd fruits.
Asian Pacific journal of cancer prevention : APJCP.
2011; 12(5):1299-305. doi:
". [PMID: 21875286] - Ila Das, Tapas Saha. Effect of garlic on lipid peroxidation and antioxidation enzymes in DMBA-induced skin carcinoma.
Nutrition (Burbank, Los Angeles County, Calif.).
2009 Apr; 25(4):459-71. doi:
10.1016/j.nut.2008.10.014. [PMID: 19084378] - Ching-Shu Lai, Shiming Li, Chee-Yin Chai, Chih-Yu Lo, Slavik Dushenkov, Chi-Tang Ho, Min-Hsiung Pan, Ying-Jan Wang. Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin.
Carcinogenesis.
2008 Dec; 29(12):2415-24. doi:
10.1093/carcin/bgn222. [PMID: 18820286] - Gopi Lilly Renju, Shanmugam Manoharan, Subramanian Balakrishnan, Namasivayam Senthil. Chemopreventive and antilipidperoxidative potential of Clerodendron inerme (L) Gaertn in 7,12-dimethylbenz(a)anthracene induced skin carcinogenesis in Swiss albino mice.
Pakistan journal of biological sciences : PJBS.
2007 May; 10(9):1465-70. doi:
10.3923/pjbs.2007.1465.1470. [PMID: 19069958] - Feral Ozturk, I Cetin Ozturk, Kadir Batcioglu, Nigar Vardi. The effect of melatonin on 7,12-dimethyl-benz[a]anthracene injury in comparison with vitamin E + selenium in mouse kidneys.
Fundamental & clinical pharmacology.
2006 Aug; 20(4):359-64. doi:
10.1111/j.1472-8206.2006.00419.x. [PMID: 16867019] - Min Ding, Rentian Feng, Shiow Y Wang, Linda Bowman, Yongju Lu, Yong Qian, Vincent Castranova, Bing-Hua Jiang, Xianglin Shi. Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity.
The Journal of biological chemistry.
2006 Jun; 281(25):17359-17368. doi:
10.1074/jbc.m600861200. [PMID: 16618699] - P Vidjaya Letchoumy, K V P Chandra Mohan, R Kumaraguruparan, Y Hara, S Nagini. Black tea polyphenols protect against 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
Oncology research.
2006; 16(4):167-78. doi:
10.3727/000000006783981116. [PMID: 17120615] - Taku Sasaki, Makoto Abe, Shin'ichi Nakayama, Kazuyuki Moriyama, Hidetaka Tahara, Toshichika Takita. Novel application of Shochu distillery by-products to prophylaxis against mammary carcinogenesis induced by 7,12-dimethylbenz[a]anthracene in rats.
Bioscience, biotechnology, and biochemistry.
2005 Oct; 69(10):1898-904. doi:
10.1271/bbb.69.1898. [PMID: 16244440] - Vaidhyanathan Bhuvaneswari, Suresh K Abraham, Siddavaram Nagini. Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis.
Nutrition (Burbank, Los Angeles County, Calif.).
2005 Jun; 21(6):726-31. doi:
10.1016/j.nut.2004.05.024. [PMID: 15925298] - V Bhuvaneswari, K S Rao, S Nagini. Altered expression of anti and proapoptotic proteins during chemoprevention of hamster buccal pouch carcinogenesis by tomato and garlic combination.
Clinica chimica acta; international journal of clinical chemistry.
2004 Dec; 350(1-2):65-72. doi:
10.1016/j.cccn.2004.07.002. [PMID: 15530461] - S Balasenthil, K S Rao, S Nagini. Garlic induces apoptosis during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
Oral oncology.
2002 Jul; 38(5):431-6. doi:
10.1016/s1368-8375(01)00084-7. [PMID: 12110336] - K Song, J A Milner. The influence of heating on the anticancer properties of garlic.
The Journal of nutrition.
2001 03; 131(3s):1054S-7S. doi:
10.1093/jn/131.3.1054s. [PMID: 11238815]