4-Methylumbelliferylguanidinobenzoate (BioDeep_00000842707)
代谢物信息卡片
化学式: C18H15N3O4 (337.10625100000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)OC(=O)C3=CC=C(C=C3)N=C(N)N
InChI: InChI=1S/C18H15N3O4/c1-10-8-16(22)25-15-9-13(6-7-14(10)15)24-17(23)11-2-4-12(5-3-11)21-18(19)20/h2-9H,1H3,(H4,19,20,21)
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- K L Smith, F S Steven, M J Tisdale. Observations on the inhibition of serum and cell surface enzymes by eicosapentaenoic acid.
Journal of enzyme inhibition.
1992; 6(4):303-15. doi:
10.3109/14756369309020180. [PMID: 1284967] - N Ohta, T Yotsuyanagi, K Ikeda. Degradation of 4'-methylumbelliferyl 4-guanidinobenzoate catalyzed by human serum albumin.
Chemical & pharmaceutical bulletin.
1988 Jun; 36(6):2152-7. doi:
10.1248/cpb.36.2152. [PMID: 3240452] - J M Kaminski, D Smith, D S Reid, W Kennedy, R S Jeyendran, L J Zaneveld. Effect of aryl 4-guanidinobenzoates on the acrosin activity of human spermatozoa.
Biology of reproduction.
1987 Jun; 36(5):1170-6. doi:
10.1095/biolreprod36.5.1170. [PMID: 3304435] - D A Benau, B T Storey. Characterization of the mouse sperm plasma membrane zona-binding site sensitive to trypsin inhibitors.
Biology of reproduction.
1987 Mar; 36(2):282-92. doi:
10.1095/biolreprod36.2.282. [PMID: 3580450] - K A Hill, F J Castellino. The effect of monovalent cations on the pre-steady state reaction kinetics of bovine activated plasma protein C and des-1-41-light chain activated plasma protein C.
The Journal of biological chemistry.
1987 Jan; 262(1):140-6. doi:
NULL. [PMID: 3793723] - A R Qureshi, H H Punnett. Carrier detection in cystic fibrosis.
The Journal of pediatrics.
1985 Jun; 106(6):913-7. doi:
10.1016/s0022-3476(85)80236-5. [PMID: 3998947] - B R Branchini, G M Salituro, B J Rosenstein. Identification of the major 4-methylumbelliferyl p-guanidinobenzoate-hydrolyzing plasma protein in cystic fibrosis: implication for intrauterine and heterozygote detection.
Pediatric research.
1983 Nov; 17(11):850-5. doi:
10.1203/00006450-198311000-00003. [PMID: 6646895] - B Tümmler, E Seger, J R Riordan. Systematic study of the hydrolysis of 4-methylumbelliferylguanidinobenzoate in plasma from patients with cystic fibrosis and controls.
Clinica chimica acta; international journal of clinical chemistry.
1982 Oct; 125(2):219-32. doi:
10.1016/0009-8981(82)90198-x. [PMID: 6754142] - M Schwartz. A serine protease activity of human serum albumin towards 4-methylumbelliferyl-guanidinobenzoate (MUGB) and diisopropyl fluorophosphate (DEP): implications for the use of MUGB reactivity in amniotic fluid in prenatal diagnosis of cystic fibrosis.
Clinica chimica acta; international journal of clinical chemistry.
1982 Sep; 124(2):213-23. doi:
10.1016/0009-8981(82)90389-8. [PMID: 6754141] - B R Branchini, G M Salituro, B J Rosenstein, W T Bruns. 4-methylumbelliferylguanidinobenzoate reactive plasma 'protease' in cystic fibrosis is albumin.
Lancet (London, England).
1982 Mar; 1(8272):618-9. doi:
10.1016/s0140-6736(82)91770-6. [PMID: 6121200] - M M Walsh, G J Rao, H L Nadler. Reaction of 4-methylumbelliferylguanidinobenzoate with proteases in human amniotic fluid.
Pediatric research.
1980 Apr; 14(4 Pt 1):353-6. doi:
10.1203/00006450-198004000-00020. [PMID: 6990368] - M Walsh-Platt, G J Rao, H L Nadler. Protease deficiency in plasma of patients with cystic fibrosis. Reduced reaction of 4-methylumbelliferylguanidinobenzoate with plasma of patients with cystic fibrosis.
Enzyme.
1979; 24(4):224-9. doi:
10.1159/000458663. [PMID: 488055] - G J Rao, M W Platt, H L Nadler. Reaction of 4-methylumbelliferylguanidinobenzoate with proteases in plasma of patients with cystic fibrosis.
Enzyme.
1978; 23(5):314-9. doi:
10.1159/000458595. [PMID: 710382]