N-Des[2-(1-methyl-2-pyrrolidinyl)ethyl] Udenafil (BioDeep_00000842675)
代谢物信息卡片
化学式: C18H23N5O4S (405.14706780000006)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N)OCCC)C
InChI: InChI=1S/C18H23N5O4S/c1-4-6-13-15-16(23(3)22-13)18(24)21-17(20-15)12-10-11(28(19,25)26)7-8-14(12)27-9-5-2/h7-8,10H,4-6,9H2,1-3H3,(H2,19,25,26)(H,20,21,24)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Soo Kyung Bae, Min Jeong Kang, Chang-Woo Yeo, Min-Jung Kim, Ji-Hong Shon, Kwang-Hyeon Liu, Jae-Gook Shin. Simultaneous determination of udenafil and its active metabolite, DA-8164, in human plasma and urine using ultra-performance liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.
Biomedical chromatography : BMC.
2008 Sep; 22(9):939-46. doi:
10.1002/bmc.1011
. [PMID: 18651603] - E Y Oh, S K Bae, J W Kwon, M You, D C Lee, M G Lee. Pharmacokinetic and pharmacodynamic consequences of inhibition of terazosin metabolism via CYP3A1 and/or 3A2 by DA-8159, an erectogenic, in rats.
British journal of pharmacology.
2007 May; 151(1):24-34. doi:
10.1038/sj.bjp.0707192
. [PMID: 17351661] - Joo H Lee, Eun J Kim, Jong W Kwon, Moohi Yoo, Myung G Lee. Negligible pharmacokinetic interaction between oral DA-8159, a new erectogenic, and amlodipine in rats.
Biopharmaceutics & drug disposition.
2006 Apr; 27(3):125-31. doi:
10.1002/bdd.491
. [PMID: 16400709] - Shin Jung Lee, Soo Kyung Bae, Jong Won Kwon, Moohi You, Duk Chul Lee, Myung Gull Lee. Pharmacokinetic interaction between 5-[2-propyloxy-5-(1-methyl-2-pyrollidinylethylamidosulfonyl)phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo (4,3-d) pyrimidine-7-one (DA-8159) and nitroglycerin in rats.
The Journal of pharmacy and pharmacology.
2005 Nov; 57(11):1397-405. doi:
10.1211/jpp.57.11.0004
. [PMID: 16259771] - Hyun J Shim, Yu C Kim, Joo H Lee, Kyung J Park, Jong W Kwon, Won B Kim, Myung G Lee. Species differences in the formation of DA-8164 after intravenous and/or oral administration of DA-8159, a new erectogenic, to mice, rats, rabbits, dogs and humans.
Biopharmaceutics & drug disposition.
2005 May; 26(4):161-6. doi:
10.1002/bdd.444
. [PMID: 15803515]