3-Iodo-alpha-methyltyrosine (BioDeep_00000842671)
代谢物信息卡片
3-Iodo-alpha-methyltyrosine
化学式: C10H12INO3 (320.9861912)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CC1=CC(=C(C=C1)O)I)(C(=O)O)N
InChI: InChI=1S/C10H12INO3/c1-10(12,9(14)15)5-6-2-3-8(13)7(11)4-6/h2-4,13H,5,12H2,1H3,(H,14,15)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D019275 - Radiopharmaceuticals
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Stefan Schildknecht, Dominik Pöltl, Daniel M Nagel, Florian Matt, Diana Scholz, Julie Lotharius, Nathalie Schmieg, Alberto Salvo-Vargas, Marcel Leist. Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells.
Toxicology and applied pharmacology.
2009 Nov; 241(1):23-35. doi:
10.1016/j.taap.2009.07.027. [PMID: 19647008] - Syuichi Nakajima, Naoto Shikano, Takashi Kotani, Masato Ogura, Ryuichi Nishii, Mitsuyoshi Yoshimoto, Naoto Yamaguchi, Yukio Iwamura, Nobuo Kubota, Nobuyoshi Ishikawa, Keiichi Kawai. Pharmacokinetics of 3-[125I]iodo-alpha-methyl-L-tyrosine, a tumor imaging agent, after probenecid loading in mice implanted with colon cancer DLD-1 cells.
Nuclear medicine and biology.
2007 Nov; 34(8):1003-8. doi:
10.1016/j.nucmedbio.2007.06.017. [PMID: 17998105] - Naoto Shikano, Syuichi Nakajima, Takashi Kotani, Yusuke Itoh, Ryuichi Nishii, Mitsuyoshi Yoshimoto, Leo Garcia Flores, Hideo Saji, Nobuyoshi Ishikawa, Keiichi Kawai. Detection of maleate-induced Fanconi syndrome by decreasing accumulation of 125I-3-iodo-alpha-methyl-L-tyrosine in the proximal tubule segment-1 region of renal cortex in mice: a trial of separate evaluation of reabsorption.
Annals of nuclear medicine.
2006 Apr; 20(3):175-81. doi:
10.1007/bf03027427. [PMID: 16715947] - Gilbert Matte, Shirley M Sangster, Matthew Acker, Marlene Hudgins, Catherine K L Too. Characterization of (123)I-iodo-alpha-methyltyrosine transport in rat lymphoma cells.
Nuclear medicine and biology.
2005 Jan; 32(1):67-73. doi:
10.1016/j.nucmedbio.2004.07.002. [PMID: 15691663] - Naoto Shikano, Keiichi Kawai, Syuichi Nakajima, Akiko Kubodera, Nobuo Kubota, Nobuyoshi Ishikawa, Hideo Saji. Transcellular transport of radioiodinated 3-iodo-alpha-methyl-L-tyrosine across monolayers of kidney epithelial cell line LLC-PK1.
Annals of nuclear medicine.
2004 May; 18(3):227-34. doi:
10.1007/bf02985004. [PMID: 15233284] - Naoto Shikano, Keiichi Kawai, Syuichi Nakajima, Ryuichi Nishii, Leo Garcia Flores, Akiko Kubodera, Nobuo Kubota, Nobuyoshi Ishikawa, Hideo Saji. Renal accumulation and excretion of radioiodinated 3-iodo-alpha-methyl-L-tyrosine.
Annals of nuclear medicine.
2004 May; 18(3):263-70. doi:
10.1007/bf02985009. [PMID: 15233289] - Naoto Shikano, Keiichi Kawai, Leo Garcia Flores, Ryuichi Nishii, Nobuo Kubota, Nobuyoshi Ishikawa, Akiko Kubodera. An artificial amino acid, 4-iodo-L-meta-tyrosine: biodistribution and excretion via kidney.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2003 Apr; 44(4):625-31. doi:
NULL. [PMID: 12679409] - Tony Lahoutte, Vicky Caveliers, Philippe R Franken, Axel Bossuyt, John Mertens, Hendrik Everaert. Increased tumor uptake of 3-(123)I-Iodo-L-alpha-methyltyrosine after preloading with amino acids: an in vivo animal imaging study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2002 Sep; 43(9):1201-6. doi:
NULL. [PMID: 12215559] - T Lahoutte, V Caveliers, L Dierickx, M Vekeman, H Everaert, J Mertens, A Bossuyt. In vitro characterization of the influx of 3-[125I]iodo-L-alpha-methyltyrosine and 2-[125I]iodo-L-tyrosine into U266 human myeloma cells: evidence for system T transport.
Nuclear medicine and biology.
2001 Feb; 28(2):129-34. doi:
10.1016/s0969-8051(00)00184-0. [PMID: 11295423] - P L Jager, E J Franssen, W Kool, B G Szabó, H J Hoekstra, H J Groen, E G de Vries, G W van Imhoff, W Vaalburg, D A Piers. Feasibility of tumor imaging using L-3-[iodine-123]-iodo-alpha-methyl-tyrosine in extracranial tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1998 Oct; 39(10):1736-43. doi:
NULL. [PMID: 9776279] - D Schmidt, K J Langen, H Herzog, J Wirths, M Holschbach, J C Kiwit, K Ziemons, H H Coenen, H Müller-Gärtner. Whole-body kinetics and dosimetry of L-3--123I-iodo-alpha-methyltyrosine.
European journal of nuclear medicine.
1997 Sep; 24(9):1162-6. doi:
10.1007/bf01254250. [PMID: 9283111] - K J Langen, N Roosen, H H Coenen, J T Kuikka, T Kuwert, H Herzog, G Stöcklin, L E Feinendegen. Brain and brain tumor uptake of L-3-[123I]iodo-alpha-methyl tyrosine: competition with natural L-amino acids.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1991 Jun; 32(6):1225-9. doi:
NULL. [PMID: 2045937] - K J Langen, H H Coenen, N Roosen, P Kling, O Muzik, H Herzog, T Kuwert, G Stöcklin, L E Feinendegen. SPECT studies of brain tumors with L-3-[123I] iodo-alpha-methyl tyrosine: comparison with PET, 124IMT and first clinical results.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1990 Mar; 31(3):281-6. doi:
NULL. [PMID: 2155314]