1-(4-Chlorophenyl)-3-((4-methylphenyl)sulfonyl)urea (BioDeep_00000842648)
代谢物信息卡片
化学式: C14H13ClN2O3S (324.0335)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2=CC=C(C=C2)Cl
InChI: InChI=1S/C14H13ClN2O3S/c1-10-2-8-13(9-3-10)21(19,20)17-14(18)16-12-6-4-11(15)5-7-12/h2-9H,1H3,(H2,16,17,18)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Frederick L Crane, Hans Löw. The oxidative function of diferric transferrin.
Biochemistry research international.
2012; 2012(?):592806. doi:
10.1155/2012/592806. [PMID: 22400117] - Pin-Ju Chueh, Chinpal Kim, NaMi Cho, Dorothy M Morré, D James Morré. Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface.
Biochemistry.
2002 Mar; 41(11):3732-41. doi:
10.1021/bi012041t. [PMID: 11888291] - D J Morré, L Y Wu, D M Morré. Response of a cell-surface NADH oxidase to the antitumor sulfonylurea N-(4-methylphenylsulfonyl)-N'-(4-chlorophenylurea) (LY181984) modulated by redox.
Biochimica et biophysica acta.
1998 Mar; 1369(2):185-92. doi:
10.1016/s0005-2736(97)00202-2. [PMID: 9518604] - D J Morré, T Reust. A circulating form of NADH oxidase activity responsive to the antitumor sulfonylurea N-4-(methylphenylsulfonyl)-N'-(4-chlorophenyl)urea (LY181984) specific to sera from cancer patients.
Journal of bioenergetics and biomembranes.
1997 Jun; 29(3):281-9. doi:
10.1023/a:1022466212083. [PMID: 9298713] - D J Morré, E Jacobs, M Sweeting, R de Cabo, D M Morré. A protein disulfide-thiol interchange activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl) urea (LY181984).
Biochimica et biophysica acta.
1997 Apr; 1325(1):117-25. doi:
10.1016/s0005-2736(96)00250-7. [PMID: 9106489] - D J Morré, L Y Wu, D M Morré. Inhibition of NADH oxidase activity and growth of HeLa cells by the antitumor sulfonylurea, N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl) urea (LY181984) and response to epidermal growth factor.
Biochimica et biophysica acta.
1997 Feb; 1355(2):114-20. doi:
10.1016/s0167-4889(96)00128-0. [PMID: 9042331] - D J Morré, F E Wilkinson, C Kim, N Cho, J Lawrence, D M Morré, D McClure. Antitumor sulfonylurea-inhibited NADH oxidase of cultured HeLa cells shed into media.
Biochimica et biophysica acta.
1996 Apr; 1280(2):197-206. doi:
10.1016/0005-2736(95)00290-1. [PMID: 8639694] - D J Morré. NADH oxidase activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl) urea (LY181984) at an external site.
Biochimica et biophysica acta.
1995 Dec; 1240(2):201-8. doi:
10.1016/0005-2736(95)00199-9. [PMID: 8541291] - D J Morré, L Y Wu, D M Morré. The antitumor sulfonylurea N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl) urea (LY181984) inhibits NADH oxidase activity of HeLa plasma membranes.
Biochimica et biophysica acta.
1995 Nov; 1240(1):11-7. doi:
10.1016/0005-2736(95)00164-7. [PMID: 7495842] - D J Morré, F E Wilkinson, J Lawrence, N Cho, M Paulik. Identification of antitumor sulfonylurea binding proteins of HeLa plasma membranes.
Biochimica et biophysica acta.
1995 Jun; 1236(2):237-43. doi:
10.1016/0005-2736(95)00053-6. [PMID: 7794962] - D J Morré, D M Morré, J Stevenson, W MacKellar, D McClure. HeLa plasma membranes bind the antitumor sulfonylurea LY181984 with high affinity.
Biochimica et biophysica acta.
1995 May; 1244(1):133-40. doi:
10.1016/0304-4165(94)00211-f. [PMID: 7766649] - R M Schultz, S L Andis, J E Toth, G B Boder, S M Rinzel, G B Grindey. Effect of albumin on antitumor activity of diarylsulfonylureas.
Anticancer research.
1993 Nov; 13(6A):1939-43. doi:
NULL. [PMID: 8297099] - J Sosinski, C Chapin, J H Thakar, P J Houghton. Influence of extracellular pH on the accumulation and cytotoxicity of N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl)urea in human cell lines.
Cancer communications.
1991; 3(12):373-81. doi:
10.3727/095535491820873696. [PMID: 16296003] - P J Houghton, F C Bailey, J A Houghton, K G Murti, J J Howbert, G B Grindey. Evidence for mitochondrial localization of N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl)urea in human colon adenocarcinoma cells.
Cancer research.
1990 Feb; 50(3):664-8. doi:
NULL. [PMID: 2297707]
