Bpd-MA (BioDeep_00000842635)

   


代谢物信息卡片


Bpd-MA

化学式: C42H44N4O8 (732.3158984)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOC(=O)C1C(=CC=C2C1(C3=CC4=C(C(=C(N4)C=C5C(=C(C(=N5)C=C6C(=C(C(=CC2=N3)N6)C)CCC(=O)O)CCC(=O)O)C)C)C=C)C)C(=O)OCC
InChI: InChI=1S/C42H44N4O8/c1-8-24-21(4)29-17-30-22(5)25(12-15-37(47)48)32(43-30)19-33-26(13-16-38(49)50)23(6)31(44-33)18-35-28-14-11-27(40(51)53-9-2)39(41(52)54-10-3)42(28,7)36(46-35)20-34(24)45-29/h8,11,14,17-20,39,44-45H,1,9-10,12-13,15-16H2,2-7H3,(H,47,48)(H,49,50)

描述信息

D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents
D003879 - Dermatologic Agents

同义名列表

1 个代谢物同义名

Bpd-MA



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Wei Zhou, Adrian Lim, Omer Hany Miligy Elmadbouh, Mouad Edderkaoui, Arsen Osipov, Angela J Mathison, Raul Urrutia, Tao Liu, Qiang Wang, Stephen J Pandol. Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells. Free radical biology & medicine. 2024 Feb; 212(?):493-504. doi: 10.1016/j.freeradbiomed.2024.01.003. [PMID: 38184120]
  • Qian Xu, Kunping Zhuo, Xiaotian Zhang, Yanru Zhen, Limin Liu, Lu Zhang, Yufan Gu, Hui Jia, Qing Chen, Meixi Liu, Jiawei Dong, Ming-Sheng Zhou. The role of angiotensin II activation of yes-associated protein/PDZ-binding motif signaling in hypertensive cardiac and vascular remodeling. European journal of pharmacology. 2024 Jan; 962(?):176252. doi: 10.1016/j.ejphar.2023.176252. [PMID: 38061470]
  • Nicholas Hoeffner, Antoni Paul, Young-Hwa Goo. Drug screen identifies verteporfin as a regulator of lipid metabolism in macrophage foam cells. Scientific reports. 2023 11; 13(1):19588. doi: 10.1038/s41598-023-46467-4. [PMID: 37949969]
  • Yiran Wang, Xinrui Huang, Qiao Zhou, Yuxin Tian, Jinmei Zuo, Zengzhi Yuan, Yichen Liu, Ju Li, Jinsheng Sun. Hippo Signaling Regulates Blastema Formation During Limb Regeneration in Chinese Mitten Crab (Eriocheir sinensis). Marine biotechnology (New York, N.Y.). 2023 Feb; 25(1):204-213. doi: 10.1007/s10126-022-10194-0. [PMID: 36586014]
  • Lennard Spanehl, Denis Revskij, Karen Bannert, Luise Ehlers, Robert Jaster. YAP activates pancreatic stellate cells and enhances pancreatic fibrosis. Hepatobiliary & pancreatic diseases international : HBPD INT. 2022 Dec; 21(6):583-589. doi: 10.1016/j.hbpd.2022.06.004. [PMID: 35753954]
  • Rui Sang, Fei Deng, Alexander Engel, Ewa Goldys, Wei Deng. Lipid-polymer nanocarrier platform enables X-ray induced photodynamic therapy against human colorectal cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Nov; 155(?):113837. doi: 10.1016/j.biopha.2022.113837. [PMID: 36271586]
  • Siyam M Ansar, Wenlei Jiang, Thilak Mudalige. Analysis of verteporfin liposomal formulations for phospholipids and phospholipid degradation products by liquid chromatography-mass spectrometry (LC-MS). Journal of pharmaceutical and biomedical analysis. 2022 Jan; 208(?):114473. doi: 10.1016/j.jpba.2021.114473. [PMID: 34814079]
  • Junjie Zhang, Qian Xu, Fu Ren, Yueyang Liu, Ruiping Cai, Yang Yao, Ming-Sheng Zhou. Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice. Canadian journal of physiology and pharmacology. 2021 Oct; 99(10):1000-1006. doi: 10.1139/cjpp-2021-0033. [PMID: 33852804]
  • Zhihuang Zheng, Chuanlei Li, Guangze Shao, Jinqing Li, Kexin Xu, Zhonghua Zhao, Zhigang Zhang, Jun Liu, Huijuan Wu. Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI. Cell death & disease. 2021 07; 12(8):754. doi: 10.1038/s41419-021-04041-8. [PMID: 34330891]
  • Sara El-Sahli, Khang Hua, Andrew Sulaiman, Jason Chambers, Li Li, Eliya Farah, Sarah McGarry, Dan Liu, Peiyong Zheng, Seung-Hwan Lee, Jiefeng Cui, Marc Ekker, Marceline Côté, Tommy Alain, Xuguang Li, Vanessa M D'Costa, Lisheng Wang, Suresh Gadde. A triple-drug nanotherapy to target breast cancer cells, cancer stem cells, and tumor vasculature. Cell death & disease. 2021 01; 12(1):8. doi: 10.1038/s41419-020-03308-w. [PMID: 33414428]
  • Xiaobing Miao, Nong Zhang. Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma. Experimental and molecular pathology. 2020 12; 117(?):104546. doi: 10.1016/j.yexmp.2020.104546. [PMID: 32976820]
  • Shenghao Li, Jingmin Ji, Zhiqin Zhang, Qing Peng, Liyuan Hao, Yinglin Guo, Wenhan Zhou, Qingzhuo Cui, Xinli Shi. Cisplatin promotes the expression level of PD-L1 in the microenvironment of hepatocellular carcinoma through YAP1. Molecular and cellular biochemistry. 2020 Dec; 475(1-2):79-91. doi: 10.1007/s11010-020-03861-0. [PMID: 32761300]
  • Changran Wei, Xiangqi Li. Determination of the migration effect and molecular docking of verteporfin in different subtypes of breast cancer cells. Molecular medicine reports. 2020 Nov; 22(5):3955-3961. doi: 10.3892/mmr.2020.11482. [PMID: 32901856]
  • Daphne Christine Salles de Oliveira, Camila Fabiano de Freitas, Italo Rodrigo Calori, Renato Sonchini Goncalves, Camila Aparecida Errerias Fernandes Cardinali, Luis Carlos Malacarne, Maria Ida Ravanelli, Hueder Paulo Moises de Oliveira, Antonio Claudio Tedesco, Wilker Caetano, Noboru Hioka, André Luiz Tessaro. Theranostic verteporfin- loaded lipid-polymer liposome for photodynamic applications. Journal of photochemistry and photobiology. B, Biology. 2020 Nov; 212(?):112039. doi: 10.1016/j.jphotobiol.2020.112039. [PMID: 33002779]
  • Jixiu Jin, Tian Wang, Woong Park, Wenjia Li, Won Kim, Sung Kwang Park, Kyung Pyo Kang. Inhibition of Yes-Associated Protein by Verteporfin Ameliorates Unilateral Ureteral Obstruction-Induced Renal Tubulointerstitial Inflammation and Fibrosis. International journal of molecular sciences. 2020 Oct; 21(21):. doi: 10.3390/ijms21218184. [PMID: 33142952]
  • Changran Wei, Xiangqi Li. Verteporfin inhibits cell proliferation and induces apoptosis in different subtypes of breast cancer cell lines without light activation. BMC cancer. 2020 Oct; 20(1):1042. doi: 10.1186/s12885-020-07555-0. [PMID: 33121449]
  • David Kessel. Paraptosis and Photodynamic Therapy: A Progress Report. Photochemistry and photobiology. 2020 09; 96(5):1096-1100. doi: 10.1111/php.13242. [PMID: 32112410]
  • Xiangxiang Zhou, Na Chen, Hongzhi Xu, Xiaoming Zhou, Jianhong Wang, Xiaosheng Fang, Ya Zhang, Ying Li, Juan Yang, Xin Wang. Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma. Journal of hematology & oncology. 2020 06; 13(1):77. doi: 10.1186/s13045-020-00906-1. [PMID: 32546241]
  • Carol L Shields, Chloe T L Khoo, Mehdi Mazloumi, Arman Mashayekhi, Jerry A Shields. Photodynamic Therapy for Choroidal Metastasis Tumor Control and Visual Outcomes in 58 Cases: The 2019 Burnier International Ocular Pathology Society Lecture. Ophthalmology. Retina. 2020 03; 4(3):310-319. doi: 10.1016/j.oret.2019.10.009. [PMID: 31953111]
  • Yuhu He, Pu Zou, Yufei Lu, Daile Jia, Xuping Li, Hui Yang, Liang Tang, Zhaowei Zhu, Tao Tu, Shi Tai, Yichao Xiao, Mingxian Chen, Lin Lu, Shenghua Zhou. Osteoprotegerin promotes intimal hyperplasia and contributes to in-stent restenosis: Role of an αVβ3/FAK dependent YAP pathway. Journal of molecular and cellular cardiology. 2020 02; 139(?):1-13. doi: 10.1016/j.yjmcc.2020.01.006. [PMID: 31958462]
  • Andrew Sulaiman, Sarah McGarry, Sara El-Sahli, Li Li, Jason Chambers, Alexandra Phan, Marceline Côté, Greg O Cron, Tommy Alain, Yevgeniya Le, Seung-Hwan Lee, Sheng Liu, Daniel Figeys, Suresh Gadde, Lisheng Wang. Co-targeting Bulk Tumor and CSCs in Clinically Translatable TNBC Patient-Derived Xenografts via Combination Nanotherapy. Molecular cancer therapeutics. 2019 10; 18(10):1755-1764. doi: 10.1158/1535-7163.mct-18-0873. [PMID: 31308079]
  • Yan Baglo, Barry J Liang, Robert W Robey, Suresh V Ambudkar, Michael M Gottesman, Huang-Chiao Huang. Porphyrin-lipid assemblies and nanovesicles overcome ABC transporter-mediated photodynamic therapy resistance in cancer cells. Cancer letters. 2019 08; 457(?):110-118. doi: 10.1016/j.canlet.2019.04.037. [PMID: 31071369]
  • J A Hurcombe, P Hartley, A C Lay, L Ni, J J Bedford, J P Leader, S Singh, A Murphy, C L Scudamore, E Marquez, A F Barrington, V Pinto, M Marchetti, L-F Wong, J Uney, M A Saleem, P W Mathieson, S Patel, R J Walker, J R Woodgett, S E Quaggin, G I Welsh, R J M Coward. Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function. Nature communications. 2019 01; 10(1):403. doi: 10.1038/s41467-018-08235-1. [PMID: 30679422]
  • Toshihiko Aki, Kana Unuma, Kanako Noritake, Naho Hirayama, Takeshi Funakoshi, Koichi Uemura. Formation of high molecular weight p62 by CORM-3. PloS one. 2019; 14(1):e0210474. doi: 10.1371/journal.pone.0210474. [PMID: 30620762]
  • Imran Rizvi, Shubhankar Nath, Girgis Obaid, Mustafa Kemal Ruhi, Kaitlin Moore, Shazia Bano, David Kessel, Tayyaba Hasan. A Combination of Visudyne and a Lipid-anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer. Photochemistry and photobiology. 2019 01; 95(1):419-429. doi: 10.1111/php.13066. [PMID: 30499113]
  • Imran Rizvi, Girgis Obaid, Shazia Bano, Tayyaba Hasan, David Kessel. Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent. Lasers in surgery and medicine. 2018 07; 50(5):499-505. doi: 10.1002/lsm.22813. [PMID: 29527710]
  • Xiao Zhao, Xiuchao Wang, Lijun Fang, Chungen Lan, Xiaowei Zheng, Yongwei Wang, Yinlong Zhang, Xuexiang Han, Shaoli Liu, Keman Cheng, Ying Zhao, Jian Shi, Jiayi Guo, Jihui Hao, He Ren, Guangjun Nie. A combinatorial strategy using YAP and pan-RAF inhibitors for treating KRAS-mutant pancreatic cancer. Cancer letters. 2017 08; 402(?):61-70. doi: 10.1016/j.canlet.2017.05.015. [PMID: 28576749]
  • Janet Y Leung, Harper L Wilson, Kristin J Voltzke, Lindsay A Williams, Hyo Jin Lee, Sara E Wobker, William Y Kim. Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis. Molecular and cellular biology. 2017 06; 37(12):. doi: 10.1128/mcb.00565-16. [PMID: 28320873]
  • Julien Massiot, Ali Makky, Florent Di Meo, David Chapron, Patrick Trouillas, Véronique Rosilio. Impact of lipid composition and photosensitizer hydrophobicity on the efficiency of light-triggered liposomal release. Physical chemistry chemical physics : PCCP. 2017 May; 19(18):11460-11473. doi: 10.1039/c7cp00983f. [PMID: 28425533]
  • Eleni K Konstantinou, Shoji Notomi, Cassandra Kosmidou, Katarzyna Brodowska, Ahmad Al-Moujahed, Fotini Nicolaou, Pavlina Tsoka, Evangelos Gragoudas, Joan W Miller, Lucy H Young, Demetrios G Vavvas. Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity. Scientific reports. 2017 04; 7(?):46581. doi: 10.1038/srep46581. [PMID: 28429726]
  • Bryan Q Spring, R Bryan Sears, Lei Zak Zheng, Zhiming Mai, Reika Watanabe, Margaret E Sherwood, David A Schoenfeld, Brian W Pogue, Stephen P Pereira, Elizabeth Villa, Tayyaba Hasan. A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways. Nature nanotechnology. 2016 Apr; 11(4):378-87. doi: 10.1038/nnano.2015.311. [PMID: 26780659]
  • Valentina Grampa, Marion Delous, Mohamad Zaidan, Gweltas Odye, Sophie Thomas, Nadia Elkhartoufi, Emilie Filhol, Olivier Niel, Flora Silbermann, Corinne Lebreton, Sophie Collardeau-Frachon, Isabelle Rouvet, Jean-Luc Alessandri, Louise Devisme, Anne Dieux-Coeslier, Marie-Pierre Cordier, Yline Capri, Suonavy Khung-Savatovsky, Sabine Sigaudy, Rémi Salomon, Corinne Antignac, Marie-Claire Gubler, Alexandre Benmerah, Fabiola Terzi, Tania Attié-Bitach, Cécile Jeanpierre, Sophie Saunier. Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. PLoS genetics. 2016 Mar; 12(3):e1005894. doi: 10.1371/journal.pgen.1005894. [PMID: 26967905]
  • Robert J House, Arman Mashayekhi, Jerry A Shields, Carol L Shields. TOTAL REGRESSION OF ACQUIRED RETINAL ASTROCYTOMA USING PHOTODYNAMIC THERAPY. Retinal cases & brief reports. 2016; 10(1):41-3. doi: 10.1097/icb.0000000000000169. [PMID: 26164044]
  • Shifalika Tangutoori, Bryan Q Spring, Zhiming Mai, Akilan Palanisami, Lawrence B Mensah, Tayyaba Hasan. Simultaneous delivery of cytotoxic and biologic therapeutics using nanophotoactivatable liposomes enhances treatment efficacy in a mouse model of pancreatic cancer. Nanomedicine : nanotechnology, biology, and medicine. 2016 Jan; 12(1):223-34. doi: 10.1016/j.nano.2015.08.007. [PMID: 26390832]
  • Xingyu Wang, Fabrizio Gronchi, Michael Bensimon, Thomas Mercier, Laurent Arthur Decosterd, Georges Wagnières, Elodie Debefve, Hans-Beat Ris, Igor Letovanec, Solange Peters, Jean Yannis Perentes. Treatment of pleural malignancies by photo-induction combined to systemic chemotherapy: Proof of concept on rodent lung tumors and feasibility study on porcine chest cavities. Lasers in surgery and medicine. 2015 Dec; 47(10):807-16. doi: 10.1002/lsm.22422. [PMID: 26415084]
  • Ning Liang, Chi Zhang, Patricia Dill, Ganna Panasyuk, Delphine Pion, Vonda Koka, Morgan Gallazzini, Eric N Olson, Hilaire Lam, Elizabeth P Henske, Zheng Dong, Udayan Apte, Nicolas Pallet, Randy L Johnson, Fabiola Terzi, David J Kwiatkowski, Jean-Yves Scoazec, Guido Martignoni, Mario Pende. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. The Journal of experimental medicine. 2014 Oct; 211(11):2249-63. doi: 10.1084/jem.20140341. [PMID: 25288394]
  • Zhongqi Xu, Aimei Li, Yongle Wang, Zhilong Chen, Takeshi Hirokawa. Pressure-assisted electrokinetic injection stacking for verteporfin drug to achieve highly sensitive enantioseparation and detection in artificial urine by capillary electrophoresis. Journal of chromatography. A. 2014 Aug; 1355(?):284-90. doi: 10.1016/j.chroma.2014.06.005. [PMID: 24951290]
  • Abdulelah A Al-Abdullah, Abdullah Al-Assiri. Resolution of bilateral corneal neovascularization and lipid keratopathy after photodynamic therapy with verteporfin. Optometry (St. Louis, Mo.). 2011 Apr; 82(4):212-4. doi: 10.1016/j.optm.2010.09.012. [PMID: 21216676]
  • Reecha Sachdeva, Hajir Dadgostar, Peter K Kaiser, Jonathan E Sears, Arun D Singh. Verteporfin photodynamic therapy of six eyes with retinal capillary haemangioma. Acta ophthalmologica. 2010 Dec; 88(8):e334-40. doi: 10.1111/j.1755-3768.2010.02008.x. [PMID: 20946329]
  • Kyung-Chul Yoon, Seong-Kyu Im, Hong-Yong Park. Recurrent herpes simplex keratitis after verteporfin photodynamic therapy for corneal neovascularization. Cornea. 2010 Apr; 29(4):465-7. doi: 10.1097/ico.0b013e3181b53310. [PMID: 20164757]
  • Jeng-Fong Chiou, Yu-Huei Wang, Mei-Jie Jou, Tsan-Zon Liu, Chia-Yang Shiau. Verteporfin-photoinduced apoptosis in HepG2 cells mediated by reactive oxygen and nitrogen species intermediates. Free radical research. 2010 Feb; 44(2):155-70. doi: 10.3109/10715760903380458. [PMID: 19886752]
  • Tsutomu Igarashi, Chiemi Yaguchi, Michinori Inage, Hisaharu Suzuki, Hiroshi Takahashi. Topographical alteration in the cornea after photodynamic therapy for neovascularization in lipid keratopathy. Japanese journal of ophthalmology. 2009 Nov; 53(6):655-657. doi: 10.1007/s10384-009-0739-7. [PMID: 20020250]
  • Minhee Cho, Irene A Barbazetto, K Bailey Freund. Refractory neovascular age-related macular degeneration secondary to polypoidal choroidal vasculopathy. American journal of ophthalmology. 2009 Jul; 148(1):70-8.e1. doi: 10.1016/j.ajo.2009.02.012. [PMID: 19403115]
  • Seong-Woo Kim, Jaeryung Oh, In Kyung Oh, Kuhl Huh. Retinal pigment epithelial tear after half fluence PDT for serous pigment epithelial detachment in central serous chorioretinopathy. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye. 2009 May; 40(3):300-3. doi: 10.3928/15428877-20090430-14. [PMID: 19485297]
  • M Reibaldi, F Boscia, T Avitabile, A Russo, V Cannemi, M G Uva, A Reibaldi. Low-fluence photodynamic therapy in longstanding chronic central serous chorioretinopathy with foveal and gravitational atrophy. European journal of ophthalmology. 2009 Jan; 19(1):154-8. doi: 10.1177/112067210901900126. [PMID: 19123167]
  • Francesco Parmeggiani, Donato Gemmati, Ciro Costagliola, Adolfo Sebastiani, Carlo Incorvaia. Predictive role of gene polymorphisms affecting thrombin-generation pathway in variable efficacy of photodynamic therapy for neovascular age-related macular degeneration. Recent patents on DNA & gene sequences. 2009; 3(2):114-22. doi: 10.2174/187221509788654151. [PMID: 19519581]
  • Sebastian Eskelin, Petri Tommila, Tapani Palosaari, Tero Kivelä. Photodynamic therapy with verteporfin to induce regression of aggressive retinal astrocytomas. Acta ophthalmologica. 2008 Nov; 86(7):794-9. doi: 10.1111/j.1755-3768.2007.01151.x. [PMID: 18759802]
  • Zale P Bernstein, Thomas Dougherty, Sandra Gollnick, Stanley A Schwartz, Supriya D Mahajan, James Kepner, Adam Sumlin, Carleton Stewart, Paul Wallace, Adaffaras Adal, Harold Walder, Bernard Poiesz. Photopheresis in HIV-1 infected patients utilizing benzoporphyrin derivative (BPD) verteporfin and light. Current HIV research. 2008 Mar; 6(2):152-63. doi: 10.2174/157016208783885001. [PMID: 18336263]
  • Margarete K Akens, Albert J M Yee, Brian C Wilson, Shane Burch, Crystal L Johnson, Lothar Lilge, Stuart K Bisland. Photodynamic therapy of vertebral metastases: evaluating tumor-to-neural tissue uptake of BPD-MA and ALA-PpIX in a murine model of metastatic human breast carcinoma. Photochemistry and photobiology. 2007 Sep; 83(5):1034-9. doi: 10.1111/j.1751-1097.2007.00172.x. [PMID: 17880497]
  • Xiaodong Zhou, Bin Chen, P Jack Hoopes, Tayyaba Hasan, Brian W Pogue. Peptide-induced inflammatory increase in vascular permeability improves photosensitizer delivery and intersubject photodynamic treatment efficacy. Radiation research. 2007 Sep; 168(3):299-307. doi: 10.1667/rr0804.1. [PMID: 17705632]
  • You-xin Chen, Jian Ge, Mi Yan, Chen-jin Jin, Mei-xia Zhang, Fang-tian Dong, Fang Lu, Cheng-fen Zhang, Jia-liang Zhao. [Clinical trial of verteporfin photodynamic therapy in Chinese age-related macular degeneration with subfoveal predominant choroidal neovascularization patients]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 2007 Mar; 43(3):198-205. doi: NULL. [PMID: 17605900]
  • Lakshmana Ayaru, Johannes Wittmann, A J Macrobert, Marco Novelli, Stephen G Bown, Stephen P Pereira. Photodynamic therapy using verteporfin photosensitization in the pancreas and surrounding tissues in the Syrian golden hamster. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2007; 7(1):20-7. doi: 10.1159/000101874. [PMID: 17449962]
  • M Vaughn Emerson, Andreas K Lauer. Emerging therapies for the treatment of neovascular age-related macular degeneration and diabetic macular edema. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 2007; 21(4):245-57. doi: 10.2165/00063030-200721040-00005. [PMID: 17628122]
  • Xiaodong Zhou, Bin Chen, P Jack Hoopes, Tayyaba Hasan, Brian W Pogue. Tumor vascular area correlates with photosensitizer uptake: analysis of verteporfin microvascular delivery in the Dunning rat prostate tumor. Photochemistry and photobiology. 2006 Sep; 82(5):1348-57. doi: 10.1562/2006-03-25-ra-858. [PMID: 17421078]
  • Kimberley S Samkoe, Matthew S Fecica, Rebecca L Goyan, Jennifer L Buchholz, Chantel Campbell, Nicole M Kelly, David T Cramb. Photobleaching kinetics of optically trapped multilamellar vesicles containing verteporfin using two-photon excitation section sign. Photochemistry and photobiology. 2006 Jan; 82(1):152-7. doi: 10.1562/2005-05-28-ra-549. [PMID: 16149861]
  • Tsung-I Peng, Cheng-Jen Chang, Mei-Jin Guo, Yu-Huai Wang, Jau-Song Yu, Hong-Yueh Wu, Mei-Jie Jou. Mitochondrion-targeted photosensitizer enhances the photodynamic effect-induced mitochondrial dysfunction and apoptosis. Annals of the New York Academy of Sciences. 2005 May; 1042(?):419-28. doi: 10.1196/annals.1338.035. [PMID: 15965088]
  • Y N Konan-Kouakou, R Boch, R Gurny, E Allémann. In vitro and in vivo activities of verteporfin-loaded nanoparticles. Journal of controlled release : official journal of the Controlled Release Society. 2005 Mar; 103(1):83-91. doi: 10.1016/j.jconrel.2004.11.023. [PMID: 15710502]
  • Brett J Rosenblatt, Gaurav K Shah, Kevin Blinder. Photodynamic therapy with verteporfin for peripapillary choroidal neovascularization. Retina (Philadelphia, Pa.). 2005 Jan; 25(1):33-7. doi: 10.1097/00006982-200501000-00004. [PMID: 15655438]
  • B J Brooks, B K Ambati, D M Marcus, A Ratanasit. Photodynamic therapy for corneal neovascularisation and lipid degeneration. The British journal of ophthalmology. 2004 Jun; 88(6):840. doi: 10.1136/bjo.2003.035071. [PMID: 15148229]
  • Xiaodong Zhou, Brian W Pogue, Bin Chen, Tayyaba Hasan. Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic Dunning prostate tumors. Photochemistry and photobiology. 2004 Apr; 79(4):323-31. doi: 10.1562/mu-03-31.1. [PMID: 15137508]
  • Kanae Ichikawa, Yoshito Takeuchi, Sei Yonezawa, Tomoya Hikita, Kohta Kurohane, Yukihiro Namba, Naoto Oku. Antiangiogenic photodynamic therapy (PDT) using Visudyne causes effective suppression of tumor growth. Cancer letters. 2004 Mar; 205(1):39-48. doi: 10.1016/j.canlet.2003.10.001. [PMID: 15036659]
  • Yufang Huang, Akira Obana, Yuko Gohto, Susumu Nakajima. Comparative study of the phototoxicity of two chrolin type photosensitizers, ATX-S10(Na) and verteporfin, on vascular endothelial and retinal pigment epithelial cells. Lasers in surgery and medicine. 2004; 34(3):216-26. doi: 10.1002/lsm.10251. [PMID: 15022248]
  • Yoshito Takeuchi, Kohta Kurohane, Kanae Ichikawa, Sei Yonezawa, Hidetsugu Ori, Takayuki Koishi, Mamoru Nango, Naoto Oku. Polycation liposome enhances the endocytic uptake of photosensitizer into cells in the presence of serum. Bioconjugate chemistry. 2003 Jul; 14(4):790-6. doi: 10.1021/bc025648a. [PMID: 12862432]
  • Maurizio Fossarello, Enrico Peiretti, Ignazio Zucca, Antonina Serra. Photodynamic therapy of corneal neovascularization with verteporfin. Cornea. 2003 Jul; 22(5):485-8. doi: 10.1097/00003226-200307000-00018. [PMID: 12827058]
  • Yoshito Takeuchi, Kohta Kurohane, Kanae Ichikawa, Sei Yonezawa, Mamoru Nango, Naoto Oku. Induction of intensive tumor suppression by antiangiogenic photodynamic therapy using polycation-modified liposomal photosensitizer. Cancer. 2003 Apr; 97(8):2027-34. doi: 10.1002/cncr.11283. [PMID: 12673734]
  • Nina Charlotte Bille Brahe Taarnhøj, Ole Kjeka, Michael Larsen. Kinetics of retinal lipoprotein precipitation and elimination after closure of subretinal new vessels. Investigative ophthalmology & visual science. 2003 Apr; 44(4):1680-5. doi: 10.1167/iovs.01-1132. [PMID: 12657609]
  • Brian W Pogue, Julia A O'Hara, Eugene Demidenko, Carmen M Wilmot, Isak A Goodwin, Bin Chen, Harold M Swartz, Tayyaba Hasan. Photodynamic therapy with verteporfin in the radiation-induced fibrosarcoma-1 tumor causes enhanced radiation sensitivity. Cancer research. 2003 Mar; 63(5):1025-33. doi: ". [PMID: 12615718]
  • Rubinah K Chowdhary, Isha Shariff, David Dolphin. Drug release characteristics of lipid based benzoporphyrin derivative. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 2003 Jan; 6(1):13-9. doi: NULL. [PMID: 12753726]
  • R Aquaron, O Forzano, J L Murati, G Fayet, C Aquaron, B Ridings. Simple, reliable and fast spectrofluorometric method for determination of plasma Verteporfin (Visudyne) levels during photodynamic therapy for choroidal neovascularization. Cellular and molecular biology (Noisy-le-Grand, France). 2002 Dec; 48(8):925-30. doi: NULL. [PMID: 12699252]
  • Shin W Kang, Shin J Kang, Hyun O Kim, Eun S Nam, Jin H Lee, Hyoung J Koh. Photodynamic therapy using verteporfin-induced minimal change nephrotic syndrome. American journal of ophthalmology. 2002 Dec; 134(6):907-8. doi: 10.1016/s0002-9394(02)01752-x. [PMID: 12470762]
  • Jean-Marie Houle, Andrew Strong. Clinical pharmacokinetics of verteporfin. Journal of clinical pharmacology. 2002 May; 42(5):547-57. doi: 10.1177/00912700222011607. [PMID: 12017349]
  • Brian W Pogue, Julia A O'Hara, Isak A Goodwin, Carmen J Wilmot, Gregory P Fournier, Altug R Akay, Harold Swartz. Tumor PO(2) changes during photodynamic therapy depend upon photosensitizer type and time after injection. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2002 May; 132(1):177-84. doi: 10.1016/s1095-6433(01)00545-1. [PMID: 12062207]
  • Masoud Panjehpour, Robert C DeNovo, Mark G Petersen, Bergein F Overholt, Robert Bower, Valery Rubinchik, Barbara Kelly. Photodynamic therapy using Verteporfin (benzoporphyrin derivative monoacid ring A, BPD-MA) and 630 nm laser light in canine esophagus. Lasers in surgery and medicine. 2002; 30(1):26-30. doi: 10.1002/lsm.10014. [PMID: 11857600]
  • Xuejun Peng, Ethan Sternberg, David Dolphin. Chiral separation of benzoporphyrin derivative mono- and diacids by laser induced fluorescence-capillary electrophoresis. Electrophoresis. 2002 Jan; 23(1):93-101. doi: 10.1002/1522-2683(200201)23:1<93::aid-elps93>3.0.co;2-h. [PMID: 11824627]
  • K J Messmer, S R Abel. Verteporfin for age-related macular degeneration. The Annals of pharmacotherapy. 2001 Dec; 35(12):1593-8. doi: 10.1345/aph.10365. [PMID: 11793628]
  • R Z Renno, J W Miller. Photosensitizer delivery for photodynamic therapy of choroidal neovascularization. Advanced drug delivery reviews. 2001 Oct; 52(1):63-78. doi: 10.1016/s0169-409x(01)00195-8. [PMID: 11672876]
  • L J Scott, K L Goa. Verteporfin. Drugs & aging. 2000 Feb; 16(2):139-46; discussion 147. doi: 10.2165/00002512-200016020-00005. [PMID: 10755329]
  • V H Fingar, P K Kik, P S Haydon, P B Cerrito, M Tseng, E Abang, T J Wieman. Analysis of acute vascular damage after photodynamic therapy using benzoporphyrin derivative (BPD). British journal of cancer. 1999 Apr; 79(11-12):1702-8. doi: 10.1038/sj.bjc.6690271. [PMID: 10206280]
  • R Hornung, M K Fehr, B J Tromberg, A Major, T B Krasieva, M W Berns, Y Tadir. Uptake of the photosensitizer benzoporphyrin derivative in human endometrium after topical application in vivo. The Journal of the American Association of Gynecologic Laparoscopists. 1998 Nov; 5(4):367-74. doi: 10.1016/s1074-3804(98)80049-2. [PMID: 9782140]
  • G C Lin, M L Tsoukas, M S Lee, S González, C Vibhagool, R R Anderson, N Kollias. Skin necrosis due to photodynamic action of benzoporphyrin depends on circulating rather than tissue drug levels: implications for control of photodynamic therapy. Photochemistry and photobiology. 1998 Oct; 68(4):575-83. doi: 10.1111/j.1751-1097.1998.tb02516.x. [PMID: 9796441]
  • F Adili, R G Statius van Eps, T J Flotte, G M LaMuraglia. Photodynamic therapy with local photosensitizer delivery inhibits experimental intimal hyperplasia. Lasers in surgery and medicine. 1998; 23(5):263-73. doi: 10.1002/(sici)1096-9101(1998)23:5<263::aid-lsm6>3.0.co;2-v. [PMID: 9888322]
  • B A Allison, M T Crespo, A K Jain, A M Richter, Y N Hsiang, J G Levy. Delivery of benzoporphyrin derivative, a photosensitizer, into atherosclerotic plaque of Watanabe heritable hyperlipidemic rabbits and balloon-injured New Zealand rabbits. Photochemistry and photobiology. 1997 May; 65(5):877-83. doi: 10.1111/j.1751-1097.1997.tb01938.x. [PMID: 9155261]
  • R Gillies, N Kollias, T Hasan, H Diddens. Spectral characterization of the benzoporphyrin derivative monoacid ring-A photoproduct formed in fetal calf solutions during irradiation with 694 nm continuous-wave radiation. Journal of photochemistry and photobiology. B, Biology. 1996 Mar; 33(1):87-90. doi: 10.1016/1011-1344(95)07222-5. [PMID: 8786464]
  • R S Labow, L A Higginson, J Irvine, M Keaney, R G Masters, J F Marquis, E Meek, T Mussivand, V M Walley, P Logan. Assessment of the cytotoxicity of the photosensitizing drug BPD verteporfin using human vascular smooth muscle cells in culture. Journal of cardiovascular pharmacology. 1995 Nov; 26(5):728-36. doi: ". [PMID: 8637187]
  • B M Aveline, T Hasan, R W Redmond. The effects of aggregation, protein binding and cellular incorporation on the photophysical properties of benzoporphyrin derivative monoacid ring A (BPDMA). Journal of photochemistry and photobiology. B, Biology. 1995 Oct; 30(2-3):161-9. doi: 10.1016/1011-1344(95)07174-z. [PMID: 8558368]
  • B A Allison, P H Pritchard, J G Levy. Evidence for low-density lipoprotein receptor-mediated uptake of benzoporphyrin derivative. British journal of cancer. 1994 May; 69(5):833-9. doi: 10.1038/bjc.1994.162. [PMID: 8180011]
  • A M Richter, A K Jain, M Obochi, H Meadows, A J Canaan, J G Levy. Activation of benzoporphyrin derivative in the circulation of mice without skin photosensitivity. Photochemistry and photobiology. 1994 Mar; 59(3):350-5. doi: 10.1111/j.1751-1097.1994.tb05046.x. [PMID: 8016215]
  • A M Richter, E Waterfield, A K Jain, A J Canaan, B A Allison, J G Levy. Liposomal delivery of a photosensitizer, benzoporphyrin derivative monoacid ring A (BPD), to tumor tissue in a mouse tumor model. Photochemistry and photobiology. 1993 Jun; 57(6):1000-6. doi: 10.1111/j.1751-1097.1993.tb02962.x. [PMID: 8367528]
  • N Davis, D Liu, A K Jain, S Y Jiang, F Jiang, A Richter, J G Levy. Modified polyvinyl alcohol-benzoporphyrin derivative conjugates as phototoxic agents. Photochemistry and photobiology. 1993 Apr; 57(4):641-7. doi: 10.1111/j.1751-1097.1993.tb02930.x. [PMID: 8506392]
  • A M Richter, A K Jain, A J Canaan, E Waterfield, E D Sternberg, J G Levy. Photosensitizing efficiency of two regioisomers of the benzoporphyrin derivative monoacid ring A (BPD-MA). Biochemical pharmacology. 1992 Jun; 43(11):2349-58. doi: 10.1016/0006-2952(92)90313-8. [PMID: 1610400]
  • J North, S Freeman, J Overbaugh, J Levy, R Lansman. Photodynamic inactivation of retrovirus by benzoporphyrin derivative: a feline leukemia virus model. Transfusion. 1992 Feb; 32(2):121-8. doi: 10.1046/j.1537-2995.1992.32292180139.x. [PMID: 1371895]
  • B A Allison, E Waterfield, A M Richter, J G Levy. The effects of plasma lipoproteins on in vitro tumor cell killing and in vivo tumor photosensitization with benzoporphyrin derivative. Photochemistry and photobiology. 1991 Nov; 54(5):709-15. doi: 10.1111/j.1751-1097.1991.tb02079.x. [PMID: 1798748]
  • B A Allison, P H Pritchard, A M Richter, J G Levy. The plasma distribution of benzoporphyrin derivative and the effects of plasma lipoproteins on its biodistribution. Photochemistry and photobiology. 1990 Sep; 52(3):501-7. doi: 10.1111/j.1751-1097.1990.tb01792.x. [PMID: 2284344]
  • A M Richter, E Waterfield, A K Jain, E D Sternberg, D Dolphin, J G Levy. In vitro evaluation of phototoxic properties of four structurally related benzoporphyrin derivatives. Photochemistry and photobiology. 1990 Sep; 52(3):495-500. doi: 10.1111/j.1751-1097.1990.tb01791.x. [PMID: 2284343]
  • A M Richter, S Cerruti-Sola, E D Sternberg, D Dolphin, J G Levy. Biodistribution of tritiated benzoporphyrin derivative (3H-BPD-MA), a new potent photosensitizer, in normal and tumor-bearing mice. Journal of photochemistry and photobiology. B, Biology. 1990 Apr; 5(2):231-44. doi: 10.1016/1011-1344(90)80008-l. [PMID: 2111398]
  • D Kessel. In vitro photosensitization with a benzoporphyrin derivative. Photochemistry and photobiology. 1989 May; 49(5):579-82. doi: 10.1111/j.1751-1097.1989.tb08426.x. [PMID: 2755992]