Astacin (BioDeep_00000842613)
natural product
代谢物信息卡片
化学式: C40H48O4 (592.3552)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C(=O)C(=O)CC2(C)C)C(C)(C)CC(=O)C1=O
InChI: InChI=1S/C40H48O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
28 个相关的物种来源信息
- 3108 - Ankistrodesmus: LTS0215408
- 6660 - Artemia: LTS0215408
- 85549 - Artemia salina: 10.1515/ZNB-1968-1016
- 85549 - Artemia salina: LTS0215408
- 38009 - Artemiidae: LTS0215408
- 6656 - Arthropoda: LTS0215408
- 6658 - Branchiopoda: LTS0215408
- 3071 - Chlorella: 10.1016/S0031-9422(00)81494-6
- 3071 - Chlorella: LTS0215408
- 35461 - Chlorellaceae: LTS0215408
- 1463548 - Chlorolobion: LTS0215408
- 34112 - Chlorolobion braunii: 10.1016/S0031-9422(00)81494-6
- 34112 - Chlorolobion braunii: LTS0215408
- 3166 - Chlorophyceae: LTS0215408
- 3041 - Chlorophyta: LTS0215408
- 2759 - Eukaryota: LTS0215408
- 33208 - Metazoa: LTS0215408
- 3070 - Oocystaceae: LTS0215408
- 3086 - Scenedesmaceae: LTS0215408
- 3087 - Scenedesmus: LTS0215408
- 104103 - Scenedesmus acutus: LTS0215408
- 3089 - Scenedesmus quadricauda: 10.1016/S0031-9422(00)81494-6
- 3089 - Scenedesmus quadricauda: LTS0215408
- 35466 - Selenastraceae: LTS0215408
- 91192 - Tetradesmus: LTS0215408
- 3088 - Tetradesmus obliquus: LTS0215408
- 75966 - Trebouxiophyceae: LTS0215408
- 33090 - Viridiplantae: LTS0215408
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Tibisay Guevara, Hagen Körschgen, Anna Cuppari, Carlo Schmitz, Michael Kuske, Irene Yiallouros, Julia Floehr, Willi Jahnen-Dechent, Walter Stöcker, F Xavier Gomis-Rüth. The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases.
Scientific reports.
2019 10; 9(1):14683. doi:
10.1038/s41598-019-51095-y. [PMID: 31604990] - Erwin E Sterchi, Walter Stöcker, Judith S Bond. Meprins, membrane-bound and secreted astacin metalloproteinases.
Molecular aspects of medicine.
2008 Oct; 29(5):309-28. doi:
10.1016/j.mam.2008.08.002. [PMID: 18783725] - V De Maere, I Vercauteren, P Geldhof, K Gevaert, J Vercruysse, E Claerebout. Molecular analysis of astacin-like metalloproteases of Ostertagia ostertagi.
Parasitology.
2005 Jan; 130(Pt 1):89-98. doi:
10.1017/s0031182004006274. [PMID: 15700760] - G D Johnson, J S Bond. Activation mechanism of meprins, members of the astacin metalloendopeptidase family.
The Journal of biological chemistry.
1997 Oct; 272(44):28126-32. doi:
10.1074/jbc.272.44.28126. [PMID: 9346968] - C H Hung, H R Huang, C J Huang, F L Huang, G D Chang. Purification and cloning of carp nephrosin, a secreted zinc endopeptidase of the astacin family.
The Journal of biological chemistry.
1997 May; 272(21):13772-8. doi:
10.1074/jbc.272.21.13772. [PMID: 9153232] - J S Bond, R J Beynon. The astacin family of metalloendopeptidases.
Protein science : a publication of the Protein Society.
1995 Jul; 4(7):1247-61. doi:
10.1002/pro.5560040701. [PMID: 7670368] - R L Wolz. A kinetic comparison of the homologous proteases astacin and meprin A.
Archives of biochemistry and biophysics.
1994 Apr; 310(1):144-51. doi:
10.1006/abbi.1994.1150. [PMID: 8161197] - D Corbeil, P E Milhiet, V Simon, J Ingram, A J Kenny, G Boileau, P Crine. Rat endopeptidase-24.18 alpha subunit is secreted into the culture medium as a zymogen when expressed by COS-1 cells.
FEBS letters.
1993 Dec; 335(3):361-6. doi:
10.1016/0014-5793(93)80420-y. [PMID: 8262184] - F X Gomis-Rüth, W Stöcker, R Huber, R Zwilling, W Bode. Refined 1.8 A X-ray crystal structure of astacin, a zinc-endopeptidase from the crayfish Astacus astacus L. Structure determination, refinement, molecular structure and comparison with thermolysin.
Journal of molecular biology.
1993 Feb; 229(4):945-68. doi:
10.1006/jmbi.1993.1098. [PMID: 8445658] - W Jiang, C M Gorbea, A V Flannery, R J Beynon, G A Grant, J S Bond. The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits.
The Journal of biological chemistry.
1992 May; 267(13):9185-93. doi:
10.1016/s0021-9258(19)50406-9. [PMID: 1374387] - E Dumermuth, E E Sterchi, W P Jiang, R L Wolz, J S Bond, A V Flannery, R J Beynon. The astacin family of metalloendopeptidases.
The Journal of biological chemistry.
1991 Nov; 266(32):21381-5. doi:
10.1016/s0021-9258(18)54648-2. [PMID: 1939172]
