Rooperol (BioDeep_00000842593)
代谢物信息卡片
化学式: C17H14O4 (282.0892)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C=C1C=CCC#CC2=CC(=C(C=C2)O)O)O)O
InChI: InChI=1S/C17H14O4/c18-14-8-6-12(10-16(14)20)4-2-1-3-5-13-7-9-15(19)17(21)11-13/h2,4,6-11,18-21H,1H2/b4-2+
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ana Amić, Denisa Mastiľák Cagardová. DFT Study of the Direct Radical Scavenging Potency of Two Natural Catecholic Compounds.
International journal of molecular sciences.
2022 Nov; 23(22):. doi:
10.3390/ijms232214497. [PMID: 36430975] - Zachary T Schwartz, Peter D Theisen, Olaf T Bjornstal, Mary Rodebaugh, Mauricio A Jemal, Dallas Lee, Spencer D Shelton, Zhenze Zhao, Liqin Du, Sean M Kerwin. Scalable Synthesis and Cancer Cell Cytotoxicity of Rooperol and Analogues.
Molecules (Basel, Switzerland).
2022 Mar; 27(6):. doi:
10.3390/molecules27061792. [PMID: 35335155] - Yan-Zhen Zheng, Zhong-Min Fu, Geng Deng, Rui Guo, Da-Fu Chen. Role of C‒H bond in the antioxidant activities of rooperol and its derivatives: A DFT study.
Phytochemistry.
2020 Oct; 178(?):112454. doi:
10.1016/j.phytochem.2020.112454. [PMID: 32692658] - Celia M J Matyanga, Gene D Morse, Mazuru Gundidza, Charles F B Nhachi. African potato (Hypoxis hemerocallidea): a systematic review of its chemistry, pharmacology and ethno medicinal properties.
BMC complementary medicine and therapies.
2020 Jun; 20(1):182. doi:
10.1186/s12906-020-02956-x. [PMID: 32527245] - Sarah Ali Azouaou, Fathi Emhemmed, Noureddine Idris-Khodja, Annelise Lobstein, Valérie Schini-Kerth, Christian D Muller, Guy Fuhrmann. Selective ROS-dependent p53-associated anticancer effects of the hypoxoside derivative rooperol on human teratocarcinomal cancer stem-like cells.
Investigational new drugs.
2015 Feb; 33(1):64-74. doi:
10.1007/s10637-014-0182-6. [PMID: 25404486] - Gerhardt J Boukes, Maryna van de Venter. Rooperol as an antioxidant and its role in the innate immune system: an in vitro study.
Journal of ethnopharmacology.
2012 Dec; 144(3):692-9. doi:
10.1016/j.jep.2012.10.014. [PMID: 23085395] - Mwadham M Kabanda. Antioxidant activity of rooperol investigated through Cu (I and II) chelation ability and the hydrogen transfer mechanism: a DFT study.
Chemical research in toxicology.
2012 Oct; 25(10):2153-66. doi:
10.1021/tx300244z. [PMID: 22946567] - Peter M O Owira, John A O Ojewole. 'African potato' (Hypoxis hemerocallidea corm): a plant-medicine for modern and 21st century diseases of mankind? - a review.
Phytotherapy research : PTR.
2009 Feb; 23(2):147-52. doi:
10.1002/ptr.2595. [PMID: 18693293] - Agatha Nyinawumuntu, Emmanuel O Awe, John A O Ojewole. Uterolytic effect of Hypoxis hemerocallidea Fisch. & C.A. Mey. (Hypoxidaceae) corm [;African Potato'] aqueous extract.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.
2008 Oct; 44(5):167-76. doi:
10.1540/jsmr.44.167. [PMID: 19122381] - Olga Laporta, Lorena Funes, María T Garzón, Jose Villalaín, Vicente Micol. Role of membranes on the antibacterial and anti-inflammatory activities of the bioactive compounds from Hypoxis rooperi corm extract.
Archives of biochemistry and biophysics.
2007 Nov; 467(1):119-31. doi:
10.1016/j.abb.2007.08.013. [PMID: 17888867] - A Guzdek, H Rokita, J Cichy, A C Allison, A Koj. Rooperol tetraacetate decreases cytokine mRNA levels and binding capacity of transcription factors in U937 cells.
Mediators of inflammation.
1998; 7(1):13-8. doi:
10.1080/09629359891324. [PMID: 9839693] - C F Albrecht, E J Theron, P B Kruger. Morphological characterisation of the cell-growth inhibitory activity of rooperol and pharmacokinetic aspects of hypoxoside as an oral prodrug for cancer therapy.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
1995 Sep; 85(9):853-60. doi:
NULL. [PMID: 8545743] - P B Kruger, C F Albrecht, R W Liebenberg, P P van Jaarsveld. Studies on hypoxoside and rooperol analogues from Hypoxis rooperi and Hypoxis latifolia and their biotransformation in man by using high-performance liquid chromatography with in-line sorption enrichment and diode-array detection.
Journal of chromatography. B, Biomedical applications.
1994 Dec; 662(1):71-8. doi:
10.1016/0378-4347(94)00392-0. [PMID: 7894695]
