7-Phenyl-7-(3-pyridyl)-6-heptenoic acid (BioDeep_00000842452)
代谢物信息卡片
化学式: C18H19NO2 (281.1415714)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C(=CCCCCC(=O)O)C2=CC=NC=C2
InChI: InChI=1S/C18H19NO2/c20-18(21)10-6-2-5-9-17(15-7-3-1-4-8-15)16-11-13-19-14-12-16/h1,3-4,7-9,11-14H,2,5-6,10H2,(H,20,21)/b17-9-
描述信息
D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents
D050299 - Fibrin Modulating Agents
D002317 - Cardiovascular Agents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Z Terashita, Y Imura, K Nishikawa. Inhibition of arachidonic acid induced-aggregation of rabbit platelets with CV-4151 (isbogrel), a selective thromboxane A2 (TXA2) synthase inhibitor: modulation of the antiplatelet action and prostanoid metabolism by rat aortic rings.
Journal of lipid mediators and cell signalling.
1996 Jan; 13(1):1-8. doi:
10.1016/0929-7855(95)00009-7. [PMID: 8821806] - Y Sasaki, N Ishiguro, T Miura. Effects of thromboxane A2 synthetase inhibitor (CV-4151) on reperfused skeletal muscle in rats.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
1994; 26(2):101-7. doi:
10.1159/000129324. [PMID: 8005166] - I S Watts, K A Wharton, B P White, P Lumley. Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti-aggregatory efficacy in human platelets.
British journal of pharmacology.
1991 Feb; 102(2):497-505. doi:
10.1111/j.1476-5381.1991.tb12200.x. [PMID: 1826620] - Y Imura, Z Terashita, K Nishikawa. The role of thromboxane (TX) A2 in rabbit arterial thrombosis induced by endothelial damage.
Thrombosis research.
1990 Jul; 59(1):195-205. doi:
10.1016/0049-3848(90)90284-j. [PMID: 2119075] - K Tanabe, H Toma, R Sagara, K Takahashi, S Teraoka, K Ota. Experimental model of chronic renal allograft rejection in rats and therapeutic efficacy of a new selective thromboxane A2 (TXA2) synthetase inhibitor (CV-4151).
Transplantation proceedings.
1989 Feb; 21(1 Pt 1):293-5. doi:
NULL. [PMID: 2650124] - T Kuzuya, Y Kimura, S Hoshida, K Kodama, N Nakamura, Y Hamanaka, A Kitabatake, T Kamada, M Tada. The effect of CV-4151, a selective inhibitor of thromboxane synthetase, on prostanoid formation and platelet aggregation in humans.
Cardiovascular drugs and therapy.
1988 Dec; 2(5):693-700. doi:
10.1007/bf00054211. [PMID: 3154645] - H Matsumura, Z Terashita, K Nishikawa, Y Imai. [Antagonism of collagen-induced ECG changes in rats by a thromboxane synthetase inhibitor, CV-4151].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1986 Apr; 87(4):397-404. doi:
10.1254/fpj.87.397. [PMID: 3755113] - Z Terashita, Y Imura, M Tanabe, K Kawazoe, K Nishikawa, K Kato, S Terao. CV-4151--a potent, selective thromboxane A2 synthetase inhibitor.
Thrombosis research.
1986 Jan; 41(2):223-37. doi:
10.1016/0049-3848(86)90231-8. [PMID: 3083523] - Y Shibouta, Z Terashita, Y Inada, K Nishikawa. Delay of the initiation of hypertension in spontaneously hypertensive rats by CV-4151, a specific thromboxane A2 synthetase inhibitor.
European journal of pharmacology.
1985 Feb; 109(2):135-44. doi:
10.1016/0014-2999(85)90414-5. [PMID: 3922775]