Thromstop (BioDeep_00000842317)
代谢物信息卡片
化学式: C27H31N5O4S (521.2096646)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CCN(CC1)C(=O)C(CC2=CC=C(C=C2)C(=N)N)NC(=O)CNS(=O)(=O)C3=CC4=CC=CC=C4C=C3
InChI: InChI=1S/C27H31N5O4S/c28-26(29)21-10-8-19(9-11-21)16-24(27(34)32-14-4-1-5-15-32)31-25(33)18-30-37(35,36)23-13-12-20-6-2-3-7-22(20)17-23/h2-3,6-13,17,24,30H,1,4-5,14-16,18H2,(H3,28,29)(H,31,33)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Valery Golderman, Shany G Gofrit, Nicola Maggio, Orna Gera, Alexandra Gerasimov, Dar Laks, Joab Chapman, Efrat Shavit-Stein. A Novel Highly Sensitive Method for Measuring Inflammatory Neural-Derived APC Activity in Glial Cell Lines, Mouse Brain and Human CSF.
International journal of molecular sciences.
2020 Mar; 21(7):. doi:
10.3390/ijms21072422. [PMID: 32244492] - Zhouling Xie, Yongbing Tian, Xiao Lv, Xuan Xiao, Meimiao Zhan, Kai Cheng, Shiyu Li, Chenzhong Liao. The selectivity and bioavailability improvement of novel oral anticoagulants: An overview.
European journal of medicinal chemistry.
2018 Feb; 146(?):299-317. doi:
10.1016/j.ejmech.2018.01.067. [PMID: 29407959] - D Prasa, L Svendsen, J Stürzebecher. Inhibition of thrombin generation in plasma by inhibitors of factor Xa.
Thrombosis and haemostasis.
1997 Oct; 78(4):1215-20. doi:
10.1055/s-0038-1657717. [PMID: 9364987] - M Reers, R Koschinsky, G Dickneite, D Hoffmann, J Czech, W Stüber. Synthesis and characterisation of novel thrombin inhibitors based on 4-amidinophenylalanine.
Journal of enzyme inhibition.
1995; 9(1):61-72. doi:
10.3109/14756369509040681. [PMID: 8568567] - J Hauptmann, B Kaiser, M Paintz, F Markwardt. Pharmacological characterization of a new structural variant of 4-amidinophenylalanine amide-type synthetic thrombin inhibitor.
Die Pharmazie.
1989 Apr; 44(4):282-4. doi:
NULL. [PMID: 2772004] - A P Bode, D T Miller. Metabolic status of platelet concentrates during extended storage: improvement with pharmacological inhibitors and reduced surface-to-volume ratio.
Vox sanguinis.
1989; 57(1):19-24. doi:
10.1111/j.1423-0410.1989.tb04978.x. [PMID: 2477949] - J Hauptmann, B Kaiser, M Paintz, F Markwardt. Biliary excretion of synthetic benzamidine-type thrombin inhibitors in rabbits and rats.
Biomedica biochimica acta.
1987; 46(6):445-53. doi:
NULL. [PMID: 3675563] - B Kaiser, F Markwardt. Antithrombotic and haemorrhagic effects of synthetic and naturally occurring thrombin inhibitors.
Thrombosis research.
1986 Sep; 43(6):613-20. doi:
10.1016/0049-3848(86)90098-8. [PMID: 3764808] - B Kaiser, J Hauptmann, A Weiss, F Markwardt. Pharmacological characterization of a new highly effective synthetic thrombin inhibitor.
Biomedica biochimica acta.
1985; 44(7-8):1201-10. doi:
NULL. [PMID: 4084272] - L Svendsen, M Brogli, G Lindeberg, K Stocker. Differentiation of thrombin- and factor Xa-related amidolytic activity in plasma by means of a synthetic thrombin inhibitor.
Thrombosis research.
1984 Jun; 34(5):457-62. doi:
10.1016/0049-3848(84)90250-0. [PMID: 6377574]