Imidazolone (BioDeep_00000842307)

   


代谢物信息卡片


Imidazolone

化学式: C3H2N2O (82.0167122)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC(=O)N=C1
InChI: InChI=1S/C3H2N2O/c6-3-4-1-2-5-3/h1-2H

描述信息

同义名列表

1 个代谢物同义名

Imidazolone



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Muniesh Muthaiyan Shanmugam, Jyotiska Chaudhuri, Durai Sellegounder, Amit Kumar Sahu, Sanjib Guha, Manish Chamoli, Brian Hodge, Neelanjan Bose, Charis Roberts, Dominique O Farrera, Gordon Lithgow, Richmond Sarpong, James J Galligan, Pankaj Kapahi. Methylglyoxal-derived hydroimidazolone, MG-H1, increases food intake by altering tyramine signaling via the GATA transcription factor ELT-3 in Caenorhabditis elegans. eLife. 2023 09; 12(?):. doi: 10.7554/elife.82446. [PMID: 37728328]
  • Wei Zhang, Beibei Zhang, Yang Ye, Hongkai Zhu. Methylglyoxal-hydroimidazolones (MG-Hs) instead of Nɛ-(carboxymethyl)-l-lysine (CML) is the major advanced glycation end-product during drying process in black tea. Food chemistry. 2020 Dec; 333(?):127499. doi: 10.1016/j.foodchem.2020.127499. [PMID: 32673957]
  • Kristina Antonova, Maria Vikhnina, Alena Soboleva, Tahir Mehmood, Marie-Louise Heymich, Tatiana Leonova, Mikhail Bankin, Elena Lukasheva, Sabrina Gensberger-Reigl, Sergei Medvedev, Galina Smolikova, Monika Pischetsrieder, Andrej Frolov. Analysis of Chemically Labile Glycation Adducts in Seed Proteins: Case Study of Methylglyoxal-Derived Hydroimidazolone 1 (MG-H1). International journal of molecular sciences. 2019 Jul; 20(15):. doi: 10.3390/ijms20153659. [PMID: 31357424]
  • Min Zhou, Hang-Ying Ma, Zhi-Hua Liu, Guang-Yu Yang, Gang Du, Yan-Qing Ye, Gan-Peng Li, Qiu-Fen Hu. (+)-Meyeniins A-C, Novel Hexahydroimidazo[1,5-c]thiazole Derivatives from the Tubers of Lepidium meyenii: Complete Structural Elucidation by Biomimetic Synthesis and Racemic Crystallization. Journal of agricultural and food chemistry. 2017 Mar; 65(9):1887-1892. doi: 10.1021/acs.jafc.6b05805. [PMID: 28212012]
  • Christopher P Mattison, Casey C Grimm, Yichen Li, Heidi J Chial, Darrell R McCaslin, Si-Yin Chung, Yvette Bren-Mattison, Richard L Wasserman. Identification and Characterization of Ana o 3 Modifications on Arginine-111 Residue in Heated Cashew Nuts. Journal of agricultural and food chemistry. 2017 Jan; 65(2):411-420. doi: 10.1021/acs.jafc.6b04134. [PMID: 27966914]
  • Zoltán Wagner, Péter Degrell, Balázs Lukáts, Toshimitsu Niwa, Gergo A Molnár, Lajos Markó, Zoltán Karádi, István Wittmann. Accumulation of renin and imidazolone in peritubular capillary endothelial cells in insulin-resistant hypertensive rats. Journal of nephrology. 2011 Sep; 24(5):656-64. doi: 10.5301/jn.2011.6520. [PMID: 21484732]
  • Michael J Kimzey, Hussein N Yassine, Brent M Riepel, George Tsaprailis, Terrence J Monks, Serrine S Lau. New site(s) of methylglyoxal-modified human serum albumin, identified by multiple reaction monitoring, alter warfarin binding and prostaglandin metabolism. Chemico-biological interactions. 2011 Jun; 192(1-2):122-8. doi: 10.1016/j.cbi.2010.09.032. [PMID: 20934417]
  • S A Manohara Reddy, Jayesh Mudgal, Punit Bansal, S G Vasanthraju, K K Srinivasan, C Mallikarjuna Rao, N Gopalan Kutty. Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives. Bioorganic & medicinal chemistry. 2011 Jan; 19(1):384-92. doi: 10.1016/j.bmc.2010.11.016. [PMID: 21146413]
  • Michelle R Baker, Sean K Benton, Christopher S Theisen, Chad A McClintick, Eugene E Fibuch, Norbert W Seidler. Isoflurane's Effect on Protein Conformation as a Proposed Mechanism for Preconditioning. Biochemistry research international. 2011; 2011(?):739712. doi: 10.1155/2011/739712. [PMID: 21918721]
  • Katsumi Mera, Kazuhiro Takeo, Miyoko Izumi, Toru Maruyama, Ryoji Nagai, Masaki Otagiri. Effect of reactive-aldehydes on the modification and dysfunction of human serum albumin. Journal of pharmaceutical sciences. 2010 Mar; 99(3):1614-25. doi: 10.1002/jps.21927. [PMID: 19760671]
  • Martin Busch, Andrea Göbert, Sybille Franke, Undine Ott, Jens Gerth, Andreas Müller, Günter Stein, Roland Bitsch, Gunter Wolf. Vitamin B6 metabolism in chronic kidney disease--relation to transsulfuration, advanced glycation and cardiovascular disease. Nephron. Clinical practice. 2010; 114(1):c38-46. doi: 10.1159/000245068. [PMID: 19816042]
  • Shahid P Baba, Oleg A Barski, Yonis Ahmed, Timothy E O'Toole, Daniel J Conklin, Aruni Bhatnagar, Sanjay Srivastava. Reductive metabolism of AGE precursors: a metabolic route for preventing AGE accumulation in cardiovascular tissue. Diabetes. 2009 Nov; 58(11):2486-97. doi: 10.2337/db09-0375. [PMID: 19651811]
  • Bente K Kilhovd, Auni Juutilainen, Seppo Lehto, Tapani Rönnemaa, Peter A Torjesen, Kristian F Hanssen, Markku Laakso. Increased serum levels of methylglyoxal-derived hydroimidazolone-AGE are associated with increased cardiovascular disease mortality in nondiabetic women. Atherosclerosis. 2009 Aug; 205(2):590-4. doi: 10.1016/j.atherosclerosis.2008.12.041. [PMID: 19185865]
  • Dag S Fosmark, Jens P Berg, Aase-Brith Jensen, Leiv Sandvik, Elisabet Agardh, Carl-David Agardh, Kristian F Hanssen. Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone. Acta ophthalmologica. 2009 Aug; 87(5):498-500. doi: 10.1111/j.1755-3768.2008.01300.x. [PMID: 18631328]
  • Rasul Ya Okmanov, Zafir U Samarov, Kambarali K Turgunov, Bakhodir Tashkhodjaev, Khusniddin M Shakhidoyatov. 6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one. Acta crystallographica. Section E, Structure reports online. 2009 Jul; 65(Pt 8):o1776. doi: 10.1107/s160053680902460x. [PMID: 21583484]
  • Yingchun Han, Edward Randell, Sudesh Vasdev, Vicki Gill, Matthew Curran, Leigh Anne Newhook, Marie Grant, Donna Hagerty, Celine Schneider. Plasma advanced glycation endproduct, methylglyoxal-derived hydroimidazolone is elevated in young, complication-free patients with Type 1 diabetes. Clinical biochemistry. 2009 May; 42(7-8):562-9. doi: 10.1016/j.clinbiochem.2008.12.016. [PMID: 19154730]
  • Waqar Ahmad, Lili Li, Yulin Deng. Identification of AGE-precursors and AGE formation in glycation-induced BSA peptides. BMB reports. 2008 Jul; 41(7):516-22. doi: 10.5483/bmbrep.2008.41.7.516. [PMID: 18682035]
  • George Suji, Santosh A Khedkar, Sreelekha K Singh, Nand Kishore, Evans C Coutinho, Vikrant M Bhor, S Sivakami. Binding of lipoic acid induces conformational change and appearance of a new binding site in methylglyoxal modified serum albumin. The protein journal. 2008 Jun; 27(4):205-14. doi: 10.1007/s10930-008-9126-3. [PMID: 18299972]
  • Mala Ranjan, Sujatha Nayak, Tanuja Kosuri, Beedu Sashidhar Rao. Immunochemical detection of glycated lens crystallins and their circulating autoantibodies in human serum during aging. Molecular vision. 2008; 14(?):2056-66. doi: NULL. [PMID: 19023447]
  • Dag S Fosmark, Ragnheidur Bragadóttir, Ingar Stene-Johansen, Jens P Berg, Tore J Berg, Terje Lund, Leiv Sandvik, Kristian F Hanssen. Increased vitreous levels of hydroimidazolone in type 2 diabetes patients are associated with retinopathy: a case-control study. Acta ophthalmologica Scandinavica. 2007 Sep; 85(6):618-22. doi: 10.1111/j.1600-0420.2007.00913.x. [PMID: 17488318]
  • Khaled A Ahmed, Sekaran Muniandy, Ikram S Ismail. Role of N-(carboxymethyl)lysine in the development of ischemic heart disease in type 2 diabetes mellitus. Journal of clinical biochemistry and nutrition. 2007 Sep; 41(2):97-105. doi: 10.3164/jcbn.2007014. [PMID: 18193103]
  • Sakurako Nakamura, Hongyan Li, Ayinuer Adijiang, Monika Pischetsrieder, Toshimitsu Niwa. Pyridoxal phosphate prevents progression of diabetic nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2007 Aug; 22(8):2165-74. doi: 10.1093/ndt/gfm166. [PMID: 17449494]
  • Moritz Butscheid, Christian Schäfer, Stefanie Brenner, Dominik Alscher, Thomas Mürdter, Toshimitsu Niwa, Matthias Frischmann, Monika Pischetsrieder, Ulrich Klotz. Unchanged serum levels of advanced glycation endproducts in patients with liver disease. Naunyn-Schmiedeberg's archives of pharmacology. 2007 Aug; 375(6):401-6. doi: 10.1007/s00210-007-0171-9. [PMID: 17571253]
  • Ying-hua Zhang, Xun-li Shi, Ya-lan Liu, Cui-ge Liu, Yong-ju Wei. [Fluorescence spectra of Dichroa febrifuga aqueous extraction]. Guang pu xue yu guang pu fen xi = Guang pu. 2007 Feb; 27(2):342-5. doi: . [PMID: 17514972]
  • Dag Sigurd Fosmark, Peter A Torjesen, Bente K Kilhovd, Tore J Berg, Leiv Sandvik, Kristian F Hanssen, Carl-David Agardh, Elisabet Agardh. Increased serum levels of the specific advanced glycation end product methylglyoxal-derived hydroimidazolone are associated with retinopathy in patients with type 2 diabetes mellitus. Metabolism: clinical and experimental. 2006 Feb; 55(2):232-6. doi: 10.1016/j.metabol.2005.08.017. [PMID: 16423631]
  • Nicole Schupp, Helga Stopper, Przemyslaw Rutkowski, Kristin Kobras, Michael Nebel, Udo Bahner, Jörg Vienken, August Heidland. Effect of different hemodialysis regimens on genomic damage in end-stage renal failure. Seminars in nephrology. 2006 Jan; 26(1):28-32. doi: 10.1016/j.semnephrol.2005.06.007. [PMID: 16412822]
  • K Kobras, N Schupp, K Nehrlich, M Adelhardt, U Bahner, J Vienken, A Heidland, K Sebekova, H Stopper. Relation between different treatment modalities and genomic damage of end-stage renal failure patients. Kidney & blood pressure research. 2006; 29(1):10-7. doi: 10.1159/000092482. [PMID: 16582572]
  • Katsumi Mera, Makoto Anraku, Kenichiro Kitamura, Keisuke Nakajou, Toru Maruyama, Kimio Tomita, Masaki Otagiri. Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients. Hypertension research : official journal of the Japanese Society of Hypertension. 2005 Dec; 28(12):973-80. doi: 10.1291/hypres.28.973. [PMID: 16671336]
  • Paul J Thornalley. Glycation free adduct accumulation in renal disease: the new AGE. Pediatric nephrology (Berlin, Germany). 2005 Nov; 20(11):1515-22. doi: 10.1007/s00467-005-2011-9. [PMID: 16133053]
  • Evangelia Fragedaki, Michael Nebel, Nicole Schupp, Katarina Sebekova, Wolfgang Völkel, André Klassen, Monika Pischetsrieder, Matthias Frischmann, Toshimitsu Niwa, Jörg Vienken, August Heidland, Helga Stopper. Genomic damage and circulating AGE levels in patients undergoing daily versus standard haemodialysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2005 Sep; 20(9):1936-43. doi: 10.1093/ndt/gfh898. [PMID: 15919695]
  • Naila Ahmed, Paul J Thornalley. Peptide mapping of human serum albumin modified minimally by methylglyoxal in vitro and in vivo. Annals of the New York Academy of Sciences. 2005 Jun; 1043(?):260-6. doi: 10.1196/annals.1333.031. [PMID: 16037246]
  • Paul J Thornalley. Dicarbonyl intermediates in the maillard reaction. Annals of the New York Academy of Sciences. 2005 Jun; 1043(?):111-7. doi: 10.1196/annals.1333.014. [PMID: 16037229]
  • Nikolaos Karachalias, Roya Babaei-Jadidi, Christian Kupich, Naila Ahmed, Paul J Thornalley. High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats. Annals of the New York Academy of Sciences. 2005 Jun; 1043(?):777-83. doi: 10.1196/annals.1333.090. [PMID: 16037305]
  • Naila Ahmed, Darin Dobler, Mark Dean, Paul J Thornalley. Peptide mapping identifies hotspot site of modification in human serum albumin by methylglyoxal involved in ligand binding and esterase activity. The Journal of biological chemistry. 2005 Feb; 280(7):5724-32. doi: 10.1074/jbc.m410973200. [PMID: 15557329]
  • Xiaohong Zhang, Matthias Frischmann, Rose Kientsch-Engel, Katharina Steinmann, Helga Stopper, Toshimitsu Niwa, Monika Pischetsrieder. Two immunochemical assays to measure advanced glycation end-products in serum from dialysis patients. Clinical chemistry and laboratory medicine. 2005; 43(5):503-11. doi: 10.1515/cclm.2005.089. [PMID: 15899672]
  • Tadashi Jono, Ryoji Nagai, Xia Lin, Naila Ahmed, Paul J Thornalley, Motohiro Takeya, Seikoh Horiuchi. Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone. Journal of biochemistry. 2004 Sep; 136(3):351-8. doi: 10.1093/jb/mvh124. [PMID: 15598892]
  • Martin Busch, Sybille Franke, Andreas Müller, Marco Wolf, Jens Gerth, Undine Ott, Toshimitsu Niwa, Günter Stein. Potential cardiovascular risk factors in chronic kidney disease: AGEs, total homocysteine and metabolites, and the C-reactive protein. Kidney international. 2004 Jul; 66(1):338-47. doi: 10.1111/j.1523-1755.2004.00736.x. [PMID: 15200442]
  • John D Williams, Nicholas Topley, Kathrine J Craig, Ruth K Mackenzie, Monika Pischetsrieder, Cristina Lage, Jutta Passlick-Deetjen. The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane. Kidney international. 2004 Jul; 66(1):408-18. doi: 10.1111/j.1523-1755.2004.00747.x. [PMID: 15200450]
  • René R Wenzel, Anna Mitchell, Winfried Siffert, Sandra Bührmann, Thomas Philipp, Rafael F Schäfers. The I1-imidazoline agonist moxonidine decreases sympathetic tone under physical and mental stress. British journal of clinical pharmacology. 2004 May; 57(5):545-51. doi: 10.1111/j.1365-2125.2003.02058.x. [PMID: 15089806]
  • N Karachalias, R Babaei-Jadidi, N Ahmed, P J Thornalley. Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochemical Society transactions. 2003 Dec; 31(Pt 6):1423-5. doi: 10.1042/bst0311423. [PMID: 14641079]
  • Sakurako Nakamura, Kazuki Tobita, Tetsuya Tachikawa, Suguru Akamatsu, Yoshifumi Ohno, Ayumi Kan, Misaki Katsuragawa, Koichi Yasumura, Shigeru Miyazaki, Shinji Sakai, Takashi Morita, Yoshihei Hirashawa, Toshimitsu Niwa. Immunohistochemical detection of an AGE, a ligand for macrophage receptor, in peritoneum of CAPD patients. Kidney international. Supplement. 2003 May; ?(84):S152-7. doi: 10.1046/j.1523-1755.63.s84.31.x. [PMID: 12694334]
  • Günter Stein, Martin Busch, Andreas Müller, Thoralf Wendt, Christiane Franke, Toshimitsu Niwa, Sybille Franke. Are advanced glycation end products cardiovascular risk factors in patients with CRF?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003 Mar; 41(3 Suppl 1):S52-6. doi: 10.1053/ajkd.2003.50085. [PMID: 12612953]
  • Andreas Tauer, Xiaohong Zhang, Thomas P Schaub, Thomas Zimmeck, Toshimitsu Niwa, Jutta Passlick-Deetjen, Monika Pischetsrieder. Formation of advanced glycation end products during CAPD. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003 Mar; 41(3 Suppl 1):S57-60. doi: 10.1053/ajkd.2003.50086. [PMID: 12612954]
  • Sakurako Nakamura, Tetsuya Tachikawa, Kazuki Tobita, Shigeru Miyazaki, Shinji Sakai, Takashi Morita, Yoshihei Hirasawa, Bernd Weigle, Monika Pischetsrieder, Toshimitsu Niwa. Role of advanced glycation end products and growth factors in peritoneal dysfunction in CAPD patients. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003 Mar; 41(3 Suppl 1):S61-7. doi: 10.1053/ajkd.2003.50087. [PMID: 12612955]
  • Maggi Burton, Catherine De Tollenaere, Jean-François Cavalier, Cécile Marchand, Frédérique Dussart, Jacqueline Marchand-Brynaert, Jean-François Rees. Synthesis, structure-activity relationship and in vitro evaluation of coelenterazine and coelenteramine derivatives as inhibitors of lipid peroxidation. Free radical research. 2003 Feb; 37(2):145-58. doi: 10.1080/1071576021000036443. [PMID: 12653203]
  • Sybille Franke, Friederike Stein, Jens Dawczynski, Marcus Blum, Ulrich Kubetschka, Günter Stein, Jürgen Strobel. Advanced glycation end-products in anterior chamber aqueous of cataractous patients. Journal of cataract and refractive surgery. 2003 Feb; 29(2):329-35. doi: 10.1016/s0886-3350(02)01524-9. [PMID: 12648645]
  • B K Kilhovd, I Giardino, P A Torjesen, K I Birkeland, T J Berg, P J Thornalley, M Brownlee, K F Hanssen. Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes. Metabolism: clinical and experimental. 2003 Feb; 52(2):163-7. doi: 10.1053/meta.2003.50035. [PMID: 12601626]
  • Ashraf Taha Khalil, Fang-Rong Chang, Yue-Han Lee, Chung-Yi Chen, Chih-Chuang Liaw, Patnam Ramesh, Shyng-Shiou F Yuan, Yang-Chang Wu. Chemical constituents from the Hydrangea chinensis. Archives of pharmacal research. 2003 Jan; 26(1):15-20. doi: 10.1007/bf03179924. [PMID: 12568351]
  • S Nakamura, S Miyazaki, S Sakai, T Morita, Y Hirasawa, T Niwa. Localization of imidazolone in the peritoneum of capd patients: a factor for a loss of ultrafiltration. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2001 Oct; 38(4 Suppl 1):S107-10. doi: 10.1053/ajkd.2001.27415. [PMID: 11576933]
  • G Xiang, R Schinzel, A Simm, G Münch, K Sebekova, M Kasper, T Niwa, C Schmitz, A Heidland. Advanced glycation end products (AGEs)-induced expression of TGF-beta 1 is suppressed by a protease in the tubule cell line LLC-PK1. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2001 Aug; 16(8):1562-9. doi: 10.1093/ndt/16.8.1562. [PMID: 11477156]
  • Gerald Cohen, Michael Rudnicki, Franziska Walter, Toshimitsu Niwa, Walter H Hörl. Glucose-modified proteins modulate essential functions and apoptosis of polymorphonuclear leukocytes. Journal of the American Society of Nephrology : JASN. 2001 Jun; 12(6):1264-1271. doi: 10.1681/asn.v1261264. [PMID: 11373351]
  • T Niwa. Dialysis-related amyloidosis: pathogenesis focusing on AGE modification. Seminars in dialysis. 2001 Mar; 14(2):123-6. doi: 10.1046/j.1525-139x.2001.00031.x. [PMID: 11264780]
  • A Tauer, T Knerr, T Niwa, T P Schaub, C Lage, J Passlick-Deetjen, M Pischetsrieder. In vitro formation of N(epsilon)-(carboxymethyl)lysine and imidazolones under conditions similar to continuous ambulatory peritoneal dialysis. Biochemical and biophysical research communications. 2001 Feb; 280(5):1408-14. doi: 10.1006/bbrc.2001.4294. [PMID: 11162688]
  • T Niwa, S Tsukushi. 3-deoxyglucosone and AGEs in uremic complications: inactivation of glutathione peroxidase by 3-deoxyglucosone. Kidney international. Supplement. 2001 Feb; 78(?):S37-41. doi: 10.1046/j.1523-1755.2001.59780037.x. [PMID: 11168980]
  • F Takayama, S Miyazaki, T Morita, Y Hirasawa, T Niwa. Dialysis-related amyloidosis of the heart in long-term hemodialysis patients. Kidney international. Supplement. 2001 Feb; 78(?):S172-6. doi: 10.1046/j.1523-1755.2001.59780172.x. [PMID: 11169005]
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