4-[2-[5,5-Dimethyl-8-(4-methylphenyl)-6H-naphthalen-2-yl]ethynyl]benzoic acid (BioDeep_00000842288)
代谢物信息卡片
化学式: C28H24O2 (392.17762039999997)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC=C(C=C1)C2=CCC(C3=C2C=C(C=C3)C#CC4=CC=C(C=C4)C(=O)O)(C)C
InChI: InChI=1S/C28H24O2/c1-19-4-11-22(12-5-19)24-16-17-28(2,3)26-15-10-21(18-25(24)26)7-6-20-8-13-23(14-9-20)27(29)30/h4-5,8-16,18H,17H2,1-3H3,(H,29,30)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yue Wang, Yunyi Chen, He Zhang, Jiebiao Chen, Jinping Cao, Qingjun Chen, Xian Li, Chongde Sun. Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2020 Dec; 146(?):111811. doi:
10.1016/j.fct.2020.111811. [PMID: 33058988] - Kyoung-Jae Won, Joo-Seop Park, Hyunyoung Jeong. Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid.
Journal of lipid research.
2019 04; 60(4):794-804. doi:
10.1194/jlr.m088880. [PMID: 30709899] - Shiamala D Manikam, Shiamala T Manikam, Johnson Stanslas. Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis.
The Journal of pharmacy and pharmacology.
2009 Jan; 61(1):69-78. doi:
10.1211/jpp/61.01.0010. [PMID: 19126299] - Istvan Szatmari, Attila Pap, Ralph Rühl, Jiang-Xing Ma, Petr A Illarionov, Gurdyal S Besra, Eva Rajnavolgyi, Balazs Dezso, Laszlo Nagy. PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells.
The Journal of experimental medicine.
2006 Oct; 203(10):2351-62. doi:
10.1084/jem.20060141. [PMID: 16982809] - Sharoni Jacobs, D Chichung Lie, Kathleen L DeCicco, Yanhong Shi, Luigi M DeLuca, Fred H Gage, Ronald M Evans. Retinoic acid is required early during adult neurogenesis in the dentate gyrus.
Proceedings of the National Academy of Sciences of the United States of America.
2006 Mar; 103(10):3902-7. doi:
10.1073/pnas.0511294103. [PMID: 16505366] - S Joshi, R Guleria, J Pan, D DiPette, U S Singh. Retinoic acid receptors and tissue-transglutaminase mediate short-term effect of retinoic acid on migration and invasion of neuroblastoma SH-SY5Y cells.
Oncogene.
2006 Jan; 25(2):240-7. doi:
10.1038/sj.onc.1209027. [PMID: 16158052] - Karine Hellemans, Krista Rombouts, Erik Quartier, Andrea S Dittié, Andreas Knorr, Liliane Michalik, Vera Rogiers, Frans Schuit, Walter Wahli, Andrea Geerts. PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation.
Journal of lipid research.
2003 Feb; 44(2):280-95. doi:
10.1194/jlr.m200376-jlr200. [PMID: 12576510] - A M Standeven, S M Thacher, Y D Yuan, M Escobar, V Vuligonda, R L Beard, R A Chandraratna. Retinoid X receptor agonist elevation of serum triglycerides in rats by potentiation of retinoic acid receptor agonist induction or by action as single agents.
Biochemical pharmacology.
2001 Dec; 62(11):1501-9. doi:
10.1016/s0006-2952(01)00803-6. [PMID: 11728386] - J M Lenhard, J E Weiel, M A Paulik, E S Furfine. Stimulation of vitamin A(1) acid signaling by the HIV protease inhibitor indinavir.
Biochemical pharmacology.
2000 May; 59(9):1063-8. doi:
10.1016/s0006-2952(00)00246-x. [PMID: 10704935] - A M Standeven, R L Beard, A T Johnson, M F Boehm, M Escobar, R A Heyman, R A Chandraratna. Retinoid-induced hypertriglyceridemia in rats is mediated by retinoic acid receptors.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1996 Oct; 33(2):264-71. doi:
10.1006/faat.1996.0164. [PMID: 8921345] - E S Klein, M E Pino, A T Johnson, P J Davies, S Nagpal, S M Thacher, G Krasinski, R A Chandraratna. Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists.
The Journal of biological chemistry.
1996 Sep; 271(37):22692-6. doi:
10.1074/jbc.271.37.22692. [PMID: 8798442]