Centhaquine (BioDeep_00000842279)
代谢物信息卡片
化学式: C22H25N3 (331.204837)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=CC=C1)N2CCN(CC2)CCC3=NC4=CC=CC=C4C=C3
InChI: InChI=1S/C22H25N3/c1-18-5-4-7-21(17-18)25-15-13-24(14-16-25)12-11-20-10-9-19-6-2-3-8-22(19)23-20/h2-10,17H,11-16H2,1H3
描述信息
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Anil Gulati, Dinesh Jain, Nilesh Radheshyam Agrawal, Prashant Rahate, Rajat Choudhuri, Soumen Das, Deba Prasad Dhibar, Madhav Prabhu, Sameer Haveri, Rohit Agarwal, Manish S Lavhale. Resuscitative Effect of Centhaquine (Lyfaquin®) in Hypovolemic Shock Patients: A Randomized, Multicentric, Controlled Trial.
Advances in therapy.
2021 06; 38(6):3223-3265. doi:
10.1007/s12325-021-01760-4. [PMID: 33970455] - Anil Gulati, Rajat Choudhuri, Ajay Gupta, Saurabh Singh, S K Noushad Ali, Gursaran Kaur Sidhu, Parvez David Haque, Prashant Rahate, Aditya R Bothra, Gyan P Singh, Sanjiv Maheshwari, Deepak Jeswani, Sameer Haveri, Apurva Agarwal, Nilesh Radheshyam Agrawal. A Multicentric, Randomized, Controlled Phase III Study of Centhaquine (Lyfaquin®) as a Resuscitative Agent in Hypovolemic Shock Patients.
Drugs.
2021 Jun; 81(9):1079-1100. doi:
10.1007/s40265-021-01547-5. [PMID: 34061314] - Zinais Kontouli, Chryssoula Staikou, Nicoletta Iacovidou, Ioannis Mamais, Evaggelia Kouskouni, Apostolos Papalois, Panagiotis Papapanagiotou, Anil Gulati, Athanasios Chalkias, Theodoros Xanthos. Resuscitation with centhaquin and 6\% hydroxyethyl starch 130/0.4 improves survival in a swine model of hemorrhagic shock: a randomized experimental study.
European journal of trauma and emergency surgery : official publication of the European Trauma Society.
2019 Dec; 45(6):1077-1085. doi:
10.1007/s00068-018-0980-1. [PMID: 30006694] - S Briyal, R Gandhakwala, M Khan, M S Lavhale, A Gulati. Alterations in endothelin receptors following hemorrhage and resuscitation by centhaquin.
Physiological research.
2018 06; 67(Suppl 1):S199-S214. doi:
10.33549/physiolres.933856. [PMID: 29947540] - Konstantina Papalexopoulou, Athanasios Chalkias, Paraskevi Pliatsika, Apostolos Papalois, Panagiotis Papapanagiotou, Georgios Papadopoulos, Eleni Arnaoutoglou, Anastasios Petrou, Anil Gulati, Theodoros Xanthos. Centhaquin Effects in a Swine Model of Ventricular Fibrillation: Centhaquin and Cardiac Arrest.
Heart, lung & circulation.
2017 Aug; 26(8):856-863. doi:
10.1016/j.hlc.2016.11.008. [PMID: 28385449] - J Nicholas O'Donnell, E Paul O'Donnell, E Jeevan Kumar, Manish S Lavhale, Shridhar V Andurkar, Anil Gulati, Marc H Scheetz. Pharmacokinetics of centhaquin citrate in a dog model.
The Journal of pharmacy and pharmacology.
2016 Jun; 68(6):803-9. doi:
10.1111/jphp.12554. [PMID: 27109141] - J Nicholas O'Donnell, Anil Gulati, Manish S Lavhale, Shyam S Sharma, Arjun J Patel, Nathaniel J Rhodes, Marc H Scheetz. Pharmacokinetics of centhaquin citrate in a rat model.
The Journal of pharmacy and pharmacology.
2016 Jan; 68(1):56-62. doi:
10.1111/jphp.12498. [PMID: 26725913] - Panagiotis Papapanagiotou, Theodoros Xanthos, Anil Gulati, Athanasios Chalkias, Apostolos Papalois, Zinais Kontouli, Athanasios Alegakis, Nicoletta Iacovidou. Centhaquin improves survival in a swine model of hemorrhagic shock.
The Journal of surgical research.
2016 Jan; 200(1):227-35. doi:
10.1016/j.jss.2015.06.056. [PMID: 26216751] - Anil Gulati, Zhong Zhang, Amy Murphy, Manish S Lavhale. Efficacy of centhaquin as a small volume resuscitative agent in severely hemorrhaged rats.
The American journal of emergency medicine.
2013 Sep; 31(9):1315-21. doi:
10.1016/j.ajem.2013.05.032. [PMID: 23871440] - Manish S Lavhale, Suresh Havalad, Anil Gulati. Resuscitative effect of centhaquin after hemorrhagic shock in rats.
The Journal of surgical research.
2013 Jan; 179(1):115-24. doi:
10.1016/j.jss.2012.08.042. [PMID: 22964270] - S Briyal, M S Lavhale, A Gulati. Repeated administration of centhaquin to pregnant rats did not affect postnatal development and expression of endothelin receptors in the brain, heart or kidney of pups.
Arzneimittel-Forschung.
2012 Dec; 62(12):670-6. doi:
10.1055/s-0032-1329985. [PMID: 23154885] - Anil Gulati, Manish S Lavhale, David J Garcia, Suresh Havalad. Centhaquin improves resuscitative effect of hypertonic saline in hemorrhaged rats.
The Journal of surgical research.
2012 Nov; 178(1):415-23. doi:
10.1016/j.jss.2012.02.005. [PMID: 22487389]