[(2-Hexylcyclopentylidene)amino]thiourea (BioDeep_00000842192)
代谢物信息卡片
[(2-Hexylcyclopentylidene)amino]thiourea
化学式: C12H23N3S (241.16125979999998)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCC1CCCC1=NNC(=S)N
InChI: InChI=1S/C12H23N3S/c1-2-3-4-5-7-10-8-6-9-11(10)14-15-12(13)16/h10H,2-9H2,1H3,(H3,13,15,16)/b14-11+
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wei Wang, Zhe Yan, Jie Hu, Wen-Jun Shen, Salman Azhar, Fredric B Kraemer. Scavenger receptor class B, type 1 facilitates cellular fatty acid uptake.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2020 02; 1865(2):158554. doi:
10.1016/j.bbalip.2019.158554. [PMID: 31678516] - Isabel Viera, Kewei Chen, José J Ríos, Itziar Benito, Antonio Pérez-Gálvez, María Roca. First-Pass Metabolism of Chlorophylls in Mice.
Molecular nutrition & food research.
2018 09; 62(17):e1800562. doi:
10.1002/mnfr.201800562. [PMID: 30028573] - Yue-Hua Feng, Lu Zheng, Jiang Wei, Miao-Mei Yu, Jun Zhang, Guang-Hua Luo, Ning Xu. Increased apolipoprotein M induced by lack of scavenger receptor BI is not activated via HDL-mediated cholesterol uptake in hepatocytes.
Lipids in health and disease.
2018 Aug; 17(1):200. doi:
10.1186/s12944-018-0849-7. [PMID: 30144814] - Kun Ren, Yan-Ju Lu, Zhong-Cheng Mo, Xing -Liu, Zhen-Li Tang, Yue Jiang, Xiao-Shan Peng, Li Li, Qing-Hai Zhang, Guang-Hui Yi. ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.
Journal of physiology and biochemistry.
2017 May; 73(2):287-296. doi:
10.1007/s13105-017-0553-5. [PMID: 28181168] - John V Cox, Yasser M Abdelrahman, Jan Peters, Nirun Naher, Robert J Belland. Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth.
Cellular microbiology.
2016 Mar; 18(3):305-18. doi:
10.1111/cmi.12523. [PMID: 26381674] - Chris Dockendorff, Patrick W Faloon, Jun Pu, Miao Yu, Stephen Johnston, Melissa Bennion, Marsha Penman, Thomas J F Nieland, Sivaraman Dandapani, José R Perez, Benito Munoz, Michelle A Palmer, Stuart L Schreiber, Monty Krieger. Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.
Bioorganic & medicinal chemistry letters.
2015; 25(10):2100-5. doi:
10.1016/j.bmcl.2015.03.073. [PMID: 25900219] - Miao Yu, Thomas Y Lau, Steven A Carr, Monty Krieger. Contributions of a disulfide bond and a reduced cysteine side chain to the intrinsic activity of the high-density lipoprotein receptor SR-BI.
Biochemistry.
2012 Dec; 51(50):10044-55. doi:
10.1021/bi301203x. [PMID: 23205738] - Emmanuelle Reboul, Zeina Soayfane, Aurélie Goncalves, Michela Cantiello, Romain Bott, Michel Nauze, François Tercé, Xavier Collet, Christine Coméra. Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies.
The British journal of nutrition.
2012 May; 107(9):1296-304. doi:
10.1017/s0007114511004405. [PMID: 21929836] - Yuki Sato, Risa Suzuki, Masaki Kobayashi, Shirou Itagaki, Takeshi Hirano, Toshihiro Noda, Satoshi Mizuno, Mitsuru Sugawara, Ken Iseki. Involvement of cholesterol membrane transporter Niemann-Pick C1-like 1 in the intestinal absorption of lutein.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2012; 15(2):256-64. doi:
10.18433/j38k56. [PMID: 22579005] - Young Hee Nam, Deulle Min, Hyoung-Pyo Kim, Kyoung-Ju Song, Kyeong Ah Kim, Young Ah Lee, Seong Hoon Kim, Myeong Heon Shin. Leukotriene B4 receptor BLT-mediated phosphorylation of NF-κB and CREB is involved in IL-8 production in human mast cells induced by Trichomonas vaginalis-derived secretory products.
Microbes and infection.
2011 Dec; 13(14-15):1211-20. doi:
10.1016/j.micinf.2011.07.006. [PMID: 21824526] - Miao Yu, Katherine A Romer, Thomas J F Nieland, Shangzhe Xu, Veronica Saenz-Vash, Marsha Penman, Ayce Yesilaltay, Steven A Carr, Monty Krieger. Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity.
Proceedings of the National Academy of Sciences of the United States of America.
2011 Jul; 108(30):12243-8. doi:
10.1073/pnas.1109078108. [PMID: 21746906] - Emmanuelle Reboul, Aurélie Goncalves, Christine Comera, Romain Bott, Marion Nowicki, Jean-François Landrier, Dominique Jourdheuil-Rahmani, Claire Dufour, Xavier Collet, Patrick Borel. Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters.
Molecular nutrition & food research.
2011 May; 55(5):691-702. doi:
10.1002/mnfr.201000553. [PMID: 21280209] - Hanna Paatela, Veera Vihma, Matti Jauhiainen, Eero Mervaala, Matti J Tikkanen. Dehydroepiandrosterone fatty acyl esters in high density lipoprotein: interaction with human vascular endothelial cells and vascular responses ex vivo.
Steroids.
2011 Mar; 76(4):376-80. doi:
10.1016/j.steroids.2010.12.007. [PMID: 21168430] - Margarita de la Llera-Moya, Denise Drazul-Schrader, Bela F Asztalos, Marina Cuchel, Daniel J Rader, George H Rothblat. The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages.
Arteriosclerosis, thrombosis, and vascular biology.
2010 Apr; 30(4):796-801. doi:
10.1161/atvbaha.109.199158. [PMID: 20075420] - Anna Gantman, Bianca Fuhrman, Michael Aviram, Tony Hayek. High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx.
Biochemical and biophysical research communications.
2010 Jan; 391(1):523-8. doi:
10.1016/j.bbrc.2009.11.091. [PMID: 19941833] - Elda Favari, Laura Calabresi, Maria Pia Adorni, Wendy Jessup, Sara Simonelli, Guido Franceschini, Franco Bernini. Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1.
Biochemistry.
2009 Nov; 48(46):11067-74. doi:
10.1021/bi901564g. [PMID: 19839639] - Demetrio Raldúa, Patrick J Babin. BLT-1, a specific inhibitor of the HDL receptor SR-BI, induces a copper-dependent phenotype during zebrafish development.
Toxicology letters.
2007 Dec; 175(1-3):1-7. doi:
10.1016/j.toxlet.2007.08.007. [PMID: 17890024]
