2-[6,8-Dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,N-dipropylacetamide (BioDeep_00000842143)
代谢物信息卡片
化学式: C21H22Cl3N3O (437.08283720000003)
中文名称:
谱图信息:
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分子结构信息
SMILES: CCCN(CCC)C(=O)CC1=C(N=C2N1C=C(C=C2Cl)Cl)C3=CC=C(C=C3)Cl
InChI: InChI=1S/C21H22Cl3N3O/c1-3-9-26(10-4-2)19(28)12-18-20(14-5-7-15(22)8-6-14)25-21-17(24)11-16(23)13-27(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3
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代谢反应
0 个相关的代谢反应过程信息。
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- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Victor W Pike, Sabrina Taliani, Talakad G Lohith, David R J Owen, Isabella Pugliesi, Eleonora Da Pozzo, Jinsoo Hong, Sami S Zoghbi, Roger N Gunn, Christine A Parker, Eugenii A Rabiner, Masahiro Fujita, Robert B Innis, Claudia Martini, Federico Da Settimo. Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.
Journal of medicinal chemistry.
2011 Jan; 54(1):366-73. doi:
10.1021/jm101230g. [PMID: 21133364] - Kevin N Boyd, Sandeep Kumar, Todd K O'Buckley, Patrizia Porcu, A Leslie Morrow. Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesis.
Journal of neurochemistry.
2010 Feb; 112(3):784-96. doi:
10.1111/j.1471-4159.2009.06509.x. [PMID: 20021565] - Enrico Sanna, Giuseppe Talani, Fabio Busonero, Maria Giuseppina Pisu, Robert H Purdy, Mariangela Serra, Giovanni Biggio. Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2004 Jul; 24(29):6521-30. doi:
10.1523/jneurosci.0075-04.2004. [PMID: 15269263] - Mariangela Serra, M Giuseppina Pisu, Ivan Floris, Silvia Floris, Emanuela Cannas, Alessandra Mossa, Giuseppe Trapani, Andrea Latrofa, Robert H Purdy, Giovanni Biggio. Social isolation increases the response of peripheral benzodiazepine receptors in the rat.
Neurochemistry international.
2004 Jul; 45(1):141-8. doi:
10.1016/j.neuint.2003.11.013. [PMID: 15082231] - G Trapani, M Franco, A Latrofa, L Ricciardi, A Carotti, M Serra, E Sanna, G Biggio, G Liso. Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies.
Journal of medicinal chemistry.
1999 Sep; 42(19):3934-41. doi:
10.1021/jm991035g. [PMID: 10508441] - M Serra, P Madau, M F Chessa, M Caddeo, E Sanna, G Trapani, M Franco, G Liso, R H Purdy, M L Barbaccia, G Biggio. 2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.
British journal of pharmacology.
1999 May; 127(1):177-87. doi:
10.1038/sj.bjp.0702530. [PMID: 10369471] - G Trapani, M Franco, L Ricciardi, A Latrofa, G Genchi, E Sanna, F Tuveri, E Cagetti, G Biggio, G Liso. Synthesis and binding affinity of 2-phenylimidazo[1,2-alpha]pyridine derivatives for both central and peripheral benzodiazepine receptors. A new series of high-affinity and selective ligands for the peripheral type.
Journal of medicinal chemistry.
1997 Sep; 40(19):3109-18. doi:
10.1021/jm970112+. [PMID: 9301675]