Bathocuproine disulfonate (BioDeep_00000842120)

   


代谢物信息卡片


Bathocuproine disulfonate

化学式: C26H20N2O6S2 (520.076274)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC(=C2C=CC3=C(C=C(N=C3C2=N1)C)C4=CC=C(C=C4)S(=O)(=O)O)C5=CC=C(C=C5)S(=O)(=O)O
InChI: InChI=1S/C26H20N2O6S2/c1-15-13-23(17-3-7-19(8-4-17)35(29,30)31)21-11-12-22-24(14-16(2)28-26(22)25(21)27-15)18-5-9-20(10-6-18)36(32,33)34/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
D064449 - Sequestering Agents > D002614 - Chelating Agents

同义名列表

1 个代谢物同义名

Bathocuproine disulfonate



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Camila Peres Rubio, Asta Tvarijonaviciute, Silvia Martinez-Subiela, Josefa Hernández-Ruiz, José Joaquin Cerón. Validation of an automated assay for the measurement of cupric reducing antioxidant capacity in serum of dogs. BMC veterinary research. 2016 Jul; 12(1):137. doi: 10.1186/s12917-016-0760-2. [PMID: 27370026]
  • Lei Chen, Xiangxin Xue, Dayu Jiang, Jin Yang, Bing Zhao, Xiao Xia Han, Young Mee Jung. A Turn-On Resonance Raman Scattering (BCS/Cu+) Sensor for Quantitative Determination of Proteins. Applied spectroscopy. 2016 Feb; 70(2):355-62. doi: 10.1177/0003702815620560. [PMID: 26903569]
  • Ranjan Tamuli, Rekha Deka, Katherine A Borkovich. Calcineurin Subunits A and B Interact to Regulate Growth and Asexual and Sexual Development in Neurospora crassa. PloS one. 2016; 11(3):e0151867. doi: 10.1371/journal.pone.0151867. [PMID: 27019426]
  • Jianbin Wang, Tim Binks, Coral G Warr, Richard Burke. Vacuolar-type H(+)-ATPase subunits and the neurogenic protein big brain are required for optimal copper and zinc uptake. Metallomics : integrated biometal science. 2014 Nov; 6(11):2100-8. doi: 10.1039/c4mt00196f. [PMID: 25209718]
  • Ricardo Gutiérrez-García, Talía del Pozo, Miriam Suazo, Verónica Cambiazo, Mauricio González. Physiological copper exposure in Jurkat cells induces changes in the expression of genes encoding cholesterol biosynthesis proteins. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2013 Dec; 26(6):1033-40. doi: 10.1007/s10534-013-9680-9. [PMID: 24170205]
  • Fabio Gosmaro, Marco Bagnati, Silvia Berto, Giorgio Bellomo, Enrico Prenesti. Measurement of total antioxidant capacity of human plasma: setting and validation of the CUPRAC-BCS method on routine apparatus ADVIA 2400. Talanta. 2013 Oct; 115(?):526-32. doi: 10.1016/j.talanta.2013.06.015. [PMID: 24054628]
  • Esin Kondakçı, Mustafa Özyürek, Kubilay Güçlü, Reşat Apak. Novel pro-oxidant activity assay for polyphenols, vitamins C and E using a modified CUPRAC method. Talanta. 2013 Oct; 115(?):583-9. doi: 10.1016/j.talanta.2013.06.006. [PMID: 24054636]
  • Ryan C McCarthy, Daniel J Kosman. Ferroportin and exocytoplasmic ferroxidase activity are required for brain microvascular endothelial cell iron efflux. The Journal of biological chemistry. 2013 Jun; 288(24):17932-40. doi: 10.1074/jbc.m113.455428. [PMID: 23640881]
  • Scot C Leary, Paul A Cobine, Tamiko Nishimura, Robert M Verdijk, Ronald de Krijger, René de Coo, Mark A Tarnopolsky, Dennis R Winge, Eric A Shoubridge. COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux. Molecular biology of the cell. 2013 Mar; 24(6):683-91. doi: 10.1091/mbc.e12-09-0705. [PMID: 23345593]
  • Shinya Ogawa, Etsuro Yoshimura. Comparison of methanol and acetonitrile eluents for the quantitation of chelators specific to soft-metal ions by HPLC. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Nov; 909(?):34-6. doi: 10.1016/j.jchromb.2012.10.005. [PMID: 23153641]
  • Carlos Campos, Rodrigo Guzmán, Encarnación López-Fernández, Angela Casado. Evaluation of the copper(II) reduction assay using bathocuproinedisulfonic acid disodium salt for the total antioxidant capacity assessment: the CUPRAC-BCS assay. Analytical biochemistry. 2009 Sep; 392(1):37-44. doi: 10.1016/j.ab.2009.05.024. [PMID: 19464250]
  • Jie Chen, Changsheng Du, Jiuhong Kang, Jianmin Wang. Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis. Chemico-biological interactions. 2008 Jan; 171(1):26-36. doi: 10.1016/j.cbi.2007.09.004. [PMID: 17961528]
  • Dola Das, Nisha Tapryal, Shyamal K Goswami, Paul L Fox, Chinmay K Mukhopadhyay. Regulation of ceruloplasmin in human hepatic cells by redox active copper: identification of a novel AP-1 site in the ceruloplasmin gene. The Biochemical journal. 2007 Feb; 402(1):135-41. doi: 10.1042/bj20060963. [PMID: 17032174]
  • Emmanuel Bourdon, Nadine Loreau, Laurent Lagrost, Denis Blache. Differential effects of cysteine and methionine residues in the antioxidant activity of human serum albumin. Free radical research. 2005 Jan; 39(1):15-20. doi: 10.1080/10715760400024935. [PMID: 15875807]
  • Reiko Sanokawa-Akakura, Huachang Dai, Shin Akakura, David Weinstein, J Eduardo Fajardo, Steven E Lang, Scott Wadsworth, John Siekierka, Raymond B Birge. A novel role for the immunophilin FKBP52 in copper transport. The Journal of biological chemistry. 2004 Jul; 279(27):27845-8. doi: 10.1074/jbc.c400118200. [PMID: 15133031]
  • Vicente Sancenón, Sergi Puig, Isabel Mateu-Andrés, Eavan Dorcey, Dennis J Thiele, Lola Peñarrubia. The Arabidopsis copper transporter COPT1 functions in root elongation and pollen development. The Journal of biological chemistry. 2004 Apr; 279(15):15348-55. doi: 10.1074/jbc.m313321200. [PMID: 14726516]
  • Byung-Eun Kim, Kathryn Smith, Carisa K Meagher, Michael J Petris. A conditional mutation affecting localization of the Menkes disease copper ATPase. Suppression by copper supplementation. The Journal of biological chemistry. 2002 Nov; 277(46):44079-84. doi: 10.1074/jbc.m208737200. [PMID: 12221109]
  • Saori Furuta, Fausto Ortiz, Xiu Zhu Sun, Hsiao-Huei Wu, Andrew Mason, Jamil Momand. Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells. The Biochemical journal. 2002 Aug; 365(Pt 3):639-48. doi: 10.1042/bj20011251. [PMID: 11964141]
  • Orit Bittner, Sigal Gal, Ilya Pinchuk, Dganit Danino, Hadassah Shinar, Dov Lichtenberg. Copper-induced peroxidation of liposomal palmitoyllinoleoylphosphatidylcholine (PLPC), effect of antioxidants and its dependence on the oxidative stress. Chemistry and physics of lipids. 2002 Jan; 114(1):81-98. doi: 10.1016/s0009-3084(01)00208-0. [PMID: 11841827]
  • I Pinchuk, S Gal, D Lichtenberg. The dose-dependent effect of copper-chelating agents on the kinetics of peroxidation of low-density lipoprotein (LDL). Free radical research. 2001 Apr; 34(4):349-62. doi: 10.1080/10715760100300301. [PMID: 11328672]
  • M J Petris, D Strausak, J F Mercer. The Menkes copper transporter is required for the activation of tyrosinase. Human molecular genetics. 2000 Nov; 9(19):2845-51. doi: 10.1093/hmg/9.19.2845. [PMID: 11092760]
  • S H Chen, S H Liu, Y C Liang, J K Lin, S Y Lin-Shiau. Death signaling pathway induced by pyrrolidine dithiocarbamate-Cu(2+) complex in the cultured rat cortical astrocytes. Glia. 2000 Sep; 31(3):249-61. doi: 10.1002/1098-1136(200009)31:3<249::aid-glia60>3.0.co;2-l. [PMID: 10941151]
  • K C Chung, J H Park, C H Kim, H W Lee, N Sato, Y Uchiyama, Y S Ahn. Novel biphasic effect of pyrrolidine dithiocarbamate on neuronal cell viability is mediated by the differential regulation of intracellular zinc and copper ion levels, NF-kappaB, and MAP kinases. Journal of neuroscience research. 2000 Jan; 59(1):117-25. doi: 10.1002/(sici)1097-4547(20000101)59:1<117::aid-jnr14>3.0.co;2-q. [PMID: 10658192]
  • J L Wood, A Graham. Reduction of transition metals by human (THP-1) monocytes is enhanced by activators of protein kinase C. Free radical research. 1999 Nov; 31(5):367-79. doi: 10.1080/10715769900300941. [PMID: 10547182]
  • C H Kim, J H Kim, J Xu, C Y Hsu, Y S Ahn. Pyrrolidine dithiocarbamate induces bovine cerebral endothelial cell death by increasing the intracellular zinc level. Journal of neurochemistry. 1999 Apr; 72(4):1586-92. doi: 10.1046/j.1471-4159.1999.721586.x. [PMID: 10098865]
  • C Perugini, M Seccia, M Bagnati, C Cau, E Albano, G Bellomo. Different mechanisms are progressively recruited to promote Cu(II) reduction by isolated human low-density lipoprotein undergoing oxidation. Free radical biology & medicine. 1998 Sep; 25(4-5):519-28. doi: 10.1016/s0891-5849(98)00075-6. [PMID: 9741588]
  • M H Falk, T Meier, R D Issels, M Brielmeier, B Scheffer, G W Bornkamm. Apoptosis in Burkitt lymphoma cells is prevented by promotion of cysteine uptake. International journal of cancer. 1998 Feb; 75(4):620-5. doi: 10.1002/(sici)1097-0215(19980209)75:4<620::aid-ijc21>3.0.co;2-b. [PMID: 9466666]
  • G W Verhaegh, M J Richard, P Hainaut. Regulation of p53 by metal ions and by antioxidants: dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper. Molecular and cellular biology. 1997 Oct; 17(10):5699-706. doi: 10.1128/mcb.17.10.5699. [PMID: 9315628]
  • Y Li, P Kuppusamy, J L Zweier, M A Trush. Role of Cu/Zn-superoxide dismutase in xenobiotic activation. I. Chemical reactions involved in the Cu/Zn-superoxide dismutase-accelerated oxidation of the benzene metabolite 1,4-hydroquinone. Molecular pharmacology. 1996 Mar; 49(3):404-11. doi: NULL. [PMID: 8643079]
  • H D Lujan, T E Nash. The uptake and metabolism of cysteine by Giardia lamblia trophozoites. The Journal of eukaryotic microbiology. 1994 Mar; 41(2):169-75. doi: 10.1111/j.1550-7408.1994.tb01491.x. [PMID: 8167619]
  • M Duszenko, K Mühlstädt, A Broder. Cysteine is an essential growth factor for Trypanosoma brucei bloodstream forms. Molecular and biochemical parasitology. 1992 Feb; 50(2):269-73. doi: 10.1016/0166-6851(92)90224-8. [PMID: 1741014]
  • Y Yabu, T Takayanagi, S Sato. An effective axenic culture system for Trypanosoma brucei rhodesiense blood stream forms in vitro. The Southeast Asian journal of tropical medicine and public health. 1990 Dec; 21(4):564-7. doi: NULL. [PMID: 2098917]
  • M H Stipanuk, J De la Rosa, L L Hirschberger. Catabolism of cyst(e)ine by rat renal cortical tubules. The Journal of nutrition. 1990 May; 120(5):450-8. doi: 10.1093/jn/120.5.450. [PMID: 2111378]
  • T Ishii, Y Sugita, S Bannai. Full replacement of 2-mercaptoethanol by cysteine plus selenium compounds in augmenting DNA synthesis of mitogen-stimulated mouse spleen lymphocytes. Cell structure and function. 1989 Jun; 14(3):287-97. doi: 10.1247/csf.14.287. [PMID: 2776226]
  • Y Yabu, T Takayanagi, S Sato. Long-term culture and cloning system for Trypanosoma brucei gambiense bloodstream forms in semi-defined medium in vitro. Parasitology research. 1989; 76(2):93-7. doi: 10.1007/bf00930828. [PMID: 2616571]
  • B H Chua, K E Giger, B J Kleinhans, J D Robishaw, H E Morgan. Differential effects of cysteine on protein and coenzyme A synthesis in rat heart. The American journal of physiology. 1984 Jul; 247(1 Pt 1):C99-106. doi: 10.1152/ajpcell.1984.247.1.c99. [PMID: 6204541]
  • A Mohindru, J M Fisher, M Rabinovitz. Bathocuproine sulphonate: a tissue culture-compatible indicator of copper-mediated toxicity. Nature. 1983 May; 303(5912):64-5. doi: 10.1038/303064a0. [PMID: 6302514]