S-Nitrosomercaptoethanol (BioDeep_00000842114)
代谢物信息卡片
S-Nitrosomercaptoethanol
化学式: C2H5NO2S (107.0041)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CSN=O)O
InChI: InChI=1S/C2H5NO2S/c4-1-2-6-3-5/h4H,1-2H2
描述信息
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors > D026403 - S-Nitrosothiols
D002317 - Cardiovascular Agents > D020030 - Nitric Oxide Donors
D000890 - Anti-Infective Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Martin Feelisch, Tienush Rassaf, Sanie Mnaimneh, Nisha Singh, Nathan S Bryan, David Jourd'Heuil, Malte Kelm. Concomitant S-, N-, and heme-nitros(yl)ation in biological tissues and fluids: implications for the fate of NO in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2002 Nov; 16(13):1775-85. doi:
10.1096/fj.02-0363com. [PMID: 12409320] - R O Cannon, A N Schechter, J A Panza, F P Ognibene, M E Pease-Fye, M A Waclawiw, J H Shelhamer, M T Gladwin. Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery.
The Journal of clinical investigation.
2001 Jul; 108(2):279-87. doi:
10.1172/jci12761. [PMID: 11457881] - K Senior. A possible molecular explanation for pre-eclampsia.
Lancet (London, England).
2001 Jun; 357(9271):1857. doi:
10.1016/s0140-6736(00)05016-9. [PMID: 11410202] - V A Tyurin, S X Liu, Y Y Tyurina, N B Sussman, C A Hubel, J M Roberts, R N Taylor, V E Kagan. Elevated levels of S-nitrosoalbumin in preeclampsia plasma.
Circulation research.
2001 Jun; 88(11):1210-5. doi:
10.1161/hh1101.092179. [PMID: 11397789] - K Wang, Z Wen, W Zhang, M Xian, J P Cheng, P G Wang. Equilibrium and kinetics studies of transnitrosation between S-nitrosothiols and thiols.
Bioorganic & medicinal chemistry letters.
2001 Feb; 11(3):433-6. doi:
10.1016/s0960-894x(00)00688-0. [PMID: 11212129] - P Moriel, I R Pereira, M C Bertolami, D S Abdalla. Is ceruloplasmin an important catalyst for S-nitrosothiol generation in hypercholesterolemia?.
Free radical biology & medicine.
2001 Feb; 30(3):318-26. doi:
10.1016/s0891-5849(00)00467-6. [PMID: 11165878] - I L Megson, N Sogo, F A Mazzei, A R Butler, J C Walton, D J Webb. Inhibition of human platelet aggregation by a novel S-nitrosothiol is abolished by haemoglobin and red blood cells in vitro: implications for anti-thrombotic therapy.
British journal of pharmacology.
2000 Dec; 131(7):1391-8. doi:
10.1038/sj.bjp.0703731. [PMID: 11090112] - D Jourd'heuil, L Gray, M B Grisham. S-nitrosothiol formation in blood of lipopolysaccharide-treated rats.
Biochemical and biophysical research communications.
2000 Jun; 273(1):22-6. doi:
10.1006/bbrc.2000.2892. [PMID: 10873557] - M Xian, K Wang, X Chen, Y Hou, A McGill, B Zhou, Z Y Zhang, J P Cheng, P G Wang. Inhibition of protein tyrosine phosphatases by low-molecular-weight S-nitrosothiols and S-nitrosylated human serum albumin.
Biochemical and biophysical research communications.
2000 Feb; 268(2):310-4. doi:
10.1006/bbrc.2000.2117. [PMID: 10679200] - D Jourd'heuil, K Hallén, M Feelisch, M B Grisham. Dynamic state of S-nitrosothiols in human plasma and whole blood.
Free radical biology & medicine.
2000 Feb; 28(3):409-17. doi:
10.1016/s0891-5849(99)00257-9. [PMID: 10699753] - R Marley, M Feelisch, S Holt, K Moore. A chemiluminescense-based assay for S-nitrosoalbumin and other plasma S-nitrosothiols.
Free radical research.
2000 Jan; 32(1):1-9. doi:
10.1080/10715760000300011. [PMID: 10625212] - S I Hammerman, E S Klings, K P Hendra, G R Upchurch, D C Rishikof, J Loscalzo, H W Farber. Endothelial cell nitric oxide production in acute chest syndrome.
The American journal of physiology.
1999 10; 277(4):H1579-92. doi:
10.1152/ajpheart.1999.277.4.h1579. [PMID: 10516198] - G Stubauer, A Giuffrè, P Sarti. Mechanism of S-nitrosothiol formation and degradation mediated by copper ions.
The Journal of biological chemistry.
1999 Oct; 274(40):28128-33. doi:
10.1074/jbc.274.40.28128. [PMID: 10497164] - K Inoue, T Akaike, Y Miyamoto, T Okamoto, T Sawa, M Otagiri, S Suzuki, T Yoshimura, H Maeda. Nitrosothiol formation catalyzed by ceruloplasmin. Implication for cytoprotective mechanism in vivo.
The Journal of biological chemistry.
1999 Sep; 274(38):27069-75. doi:
10.1074/jbc.274.38.27069. [PMID: 10480920] - B Gaston, E Fry, S Sears, W M Heroman, L Ignarro, J S Stamler. Umbilical arterial S-nitrosothiols in stressed newborns: role in perinatal circulatory transition.
Biochemical and biophysical research communications.
1998 Dec; 253(3):899-901. doi:
10.1006/bbrc.1998.9865. [PMID: 9918827] - J F Ewing, D R Janero. Specific S-nitrosothiol (thionitrite) quantification as solution nitrite after vanadium(III) reduction and ozone-chemiluminescent detection.
Free radical biology & medicine.
1998 Sep; 25(4-5):621-8. doi:
10.1016/s0891-5849(98)00083-5. [PMID: 9741600] - R K Goldman, A A Vlessis, D D Trunkey. Nitrosothiol quantification in human plasma.
Analytical biochemistry.
1998 May; 259(1):98-103. doi:
10.1006/abio.1998.2651. [PMID: 9606149] - J E Graves, S J Lewis, N W Kooy. Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols.
The American journal of physiology.
1998 03; 274(3):H1001-8. doi:
10.1152/ajpheart.1998.274.3.h1001. [PMID: 9530214] - M Nishikawa, E F Sato, M Kashiba, T Kuroki, K Utsumi, M Inoue. Role of glutathione in nitric oxide-dependent regulation of energy metabolism in rat hepatoma cells.
Hepatology (Baltimore, Md.).
1998 Feb; 27(2):422-6. doi:
10.1002/hep.510270216. [PMID: 9462640] - H Hu, N Chiamvimonvat, T Yamagishi, E Marban. Direct inhibition of expressed cardiac L-type Ca2+ channels by S-nitrosothiol nitric oxide donors.
Circulation research.
1997 Nov; 81(5):742-52. doi:
10.1161/01.res.81.5.742. [PMID: 9351448] - M Marzinzig, A K Nussler, J Stadler, E Marzinzig, W Barthlen, N C Nussler, H G Beger, S M Morris, U B Brückner. Improved methods to measure end products of nitric oxide in biological fluids: nitrite, nitrate, and S-nitrosothiols.
Nitric oxide : biology and chemistry.
1997 Apr; 1(2):177-89. doi:
10.1006/niox.1997.0116. [PMID: 9701056] - R L Davisson, M D Travis, J N Bates, S J Lewis. Hemodynamic effects of L- and D-S-nitrosocysteine in the rat. Stereoselective S-nitrosothiol recognition sites.
Circulation research.
1996 Aug; 79(2):256-62. doi:
10.1161/01.res.79.2.256. [PMID: 8756002] - J A Cook, S Y Kim, D Teague, M C Krishna, R Pacelli, J B Mitchell, Y Vodovotz, R W Nims, D Christodoulou, A M Miles, M B Grisham, D A Wink. Convenient colorimetric and fluorometric assays for S-nitrosothiols.
Analytical biochemistry.
1996 Jul; 238(2):150-8. doi:
10.1006/abio.1996.0268. [PMID: 8660604] - P Rauhala, K P Mohanakumar, I Sziraki, A M Lin, C C Chiueh. S-nitrosothiols and nitric oxide, but not sodium nitroprusside, protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo.
Synapse (New York, N.Y.).
1996 May; 23(1):58-60. doi:
10.1002/(sici)1098-2396(199605)23:1<58::aid-syn7>3.0.co;2-g. [PMID: 8723136] - J W Park. Attenuation of p47phox and p67phox membrane translocation as the inhibitory mechanism of S-nitrosothiol on the respiratory burst oxidase in human neutrophils.
Biochemical and biophysical research communications.
1996 Mar; 220(1):31-5. doi:
10.1006/bbrc.1996.0351. [PMID: 8602852] - J E Freedman, B Frei, G N Welch, J Loscalzo. Glutathione peroxidase potentiates the inhibition of platelet function by S-nitrosothiols.
The Journal of clinical investigation.
1995 Jul; 96(1):394-400. doi:
10.1172/jci118047. [PMID: 7615810] - J S Stamler. S-nitrosothiols and the bioregulatory actions of nitrogen oxides through reactions with thiol groups.
Current topics in microbiology and immunology.
1995; 196(?):19-36. doi:
10.1007/978-3-642-79130-7_4. [PMID: 7634823] - J S Scharfstein, J F Keaney, A Slivka, G N Welch, J A Vita, J S Stamler, J Loscalzo. In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols.
The Journal of clinical investigation.
1994 Oct; 94(4):1432-9. doi:
10.1172/jci117480. [PMID: 7929818] - B Gaston, J M Drazen, A Jansen, D A Sugarbaker, J Loscalzo, W Richards, J S Stamler. Relaxation of human bronchial smooth muscle by S-nitrosothiols in vitro.
The Journal of pharmacology and experimental therapeutics.
1994 Feb; 268(2):978-84. doi:
NULL. [PMID: 7906736] - A Jansen, J Drazen, J A Osborne, R Brown, J Loscalzo, J S Stamler. The relaxant properties in guinea pig airways of S-nitrosothiols.
The Journal of pharmacology and experimental therapeutics.
1992 Apr; 261(1):154-60. doi:
NULL. [PMID: 1560360] - J A Bauer, H L Fung. Differential hemodynamic effects and tolerance properties of nitroglycerin and an S-nitrosothiol in experimental heart failure.
The Journal of pharmacology and experimental therapeutics.
1991 Jan; 256(1):249-54. doi:
NULL. [PMID: 1899118] - S Chong, H L Fung. Thiol-mediated catalysis of nitroglycerin degradation by serum proteins. Increase in metabolism was not accompanied by S-nitrosothiol production.
Drug metabolism and disposition: the biological fate of chemicals.
1990 Jan; 18(1):61-7. doi:
NULL. [PMID: 1970779]
