6-Chloro-5-methyl-N-(quinolin-5-yl)indoline-1-carboxamide (BioDeep_00000842087)
代谢物信息卡片
化学式: C19H16ClN3O (337.0981836)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC2=C(C=C1Cl)N(CC2)C(=O)NC3=CC=CC4=C3C=CC=N4
InChI: InChI=1S/C19H16ClN3O/c1-12-10-13-7-9-23(18(13)11-15(12)20)19(24)22-17-6-2-5-16-14(17)4-3-8-21-16/h2-6,8,10-11H,7,9H2,1H3,(H,22,24)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chihiro Yamada, Yayoi Saegusa, Koji Nakagawa, Shunsuke Ohnishi, Shuichi Muto, Miwa Nahata, Chiharu Sadakane, Tomohisa Hattori, Naoya Sakamoto, Hiroshi Takeda. Rikkunshito, a Japanese kampo medicine, ameliorates decreased feeding behavior via ghrelin and serotonin 2B receptor signaling in a novelty stress murine model.
BioMed research international.
2013; 2013(?):792940. doi:
10.1155/2013/792940. [PMID: 24288687] - Neil Moss, Younggi Choi, Derek Cogan, Adam Flegg, Andreas Kahrs, Pui Loke, Orietta Meyn, Raj Nagaraja, Spencer Napier, Ashley Parker, J Thomas Peterson, Philip Ramsden, Christopher Sarko, Donna Skow, Josh Tomlinson, Heather Tye, Mark Whitaker. A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties.
Bioorganic & medicinal chemistry letters.
2009 Apr; 19(8):2206-10. doi:
10.1016/j.bmcl.2009.02.126. [PMID: 19307114] - Hiroshi Takeda, Chiharu Sadakane, Tomohisa Hattori, Takehiko Katsurada, Tatsuya Ohkawara, Koichi Nagai, Masahiro Asaka. Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.
Gastroenterology.
2008 Jun; 134(7):2004-13. doi:
10.1053/j.gastro.2008.02.078. [PMID: 18439428] - Yao-Jen Liang, Ling-Ping Lai, Bao-Wei Wang, Shiow-Jen Juang, Che-Ming Chang, Jyh-Gang Leu, Kou-Gi Shyu. Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kappaB in cardiomyocytes.
Cardiovascular research.
2006 Nov; 72(2):303-12. doi:
10.1016/j.cardiores.2006.08.003. [PMID: 16962085] - Fabrice Jaffré, Jacques Callebert, Alexandre Sarre, Nelly Etienne, Canan G Nebigil, Jean-Marie Launay, Luc Maroteaux, Laurent Monassier. Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts.
Circulation.
2004 Aug; 110(8):969-74. doi:
10.1161/01.cir.0000139856.20505.57. [PMID: 15302781] - C Reavill, A Kettle, V Holland, G Riley, T P Blackburn. Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist.
British journal of pharmacology.
1999 Feb; 126(3):572-4. doi:
10.1038/sj.bjp.0702350. [PMID: 10188965]