Modipafant racemate (BioDeep_00000842076)
代谢物信息卡片
化学式: C34H29ClN6O3 (604.1989554)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)NC3=CC=CC=N3)C)C4=CC=C(C=C4)N5C(=NC6=C5C=CN=C6)C
InChI: InChI=1S/C34H29ClN6O3/c1-4-44-34(43)31-30(24-9-5-6-10-25(24)35)29(33(42)40-28-11-7-8-17-37-28)20(2)38-32(31)22-12-14-23(15-13-22)41-21(3)39-26-19-36-18-16-27(26)41/h5-19,30,38H,4H2,1-3H3,(H,37,40,42)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Caroline Bélanger, Hanan Elimam, Julie Lefebvre, Pierre Borgeat, Sylvie Marleau. Involvement of endogenous leukotriene B4 and platelet-activating factor in polymorphonuclear leucocyte recruitment to dermal inflammatory sites in rats.
Immunology.
2008 Jul; 124(3):295-303. doi:
10.1111/j.1365-2567.2007.02767.x. [PMID: 18217950] - Danielle G Souza, Vanessa Pinho, Adriana C Soares, Takao Shimizu, Satoshi Ishii, Mauro M Teixeira. Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment.
British journal of pharmacology.
2003 Jun; 139(4):733-40. doi:
10.1038/sj.bjp.0705296. [PMID: 12812996] - A C Soares, V S Pinho, D G Souza, T Shimizu, S Ishii, J R Nicoli, M M Teixeira. Role of the platelet-activating factor (PAF) receptor during pulmonary infection with gram negative bacteria.
British journal of pharmacology.
2002 Nov; 137(5):621-8. doi:
10.1038/sj.bjp.0704918. [PMID: 12381675] - J M Miotla, P K Jeffery, P G Hellewell. Platelet-activating factor plays a pivotal role in the induction of experimental lung injury.
American journal of respiratory cell and molecular biology.
1998 Feb; 18(2):197-204. doi:
10.1165/ajrcmb.18.2.2846. [PMID: 9476906] - K E Norman, T J Williams, A G Rossi. Comparison of the reversed passive Arthus and local Shwartzman reactions of rabbit skin: effects of the long-acting PAF antagonist UK-74,505.
British journal of pharmacology.
1997 Apr; 120(7):1286-93. doi:
10.1038/sj.bjp.0701057. [PMID: 9105704] - M J Sanz, V B Weg, D T Walsh, T J Williams, S Nourshargh. Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.
British journal of pharmacology.
1994 Oct; 113(2):513-21. doi:
10.1111/j.1476-5381.1994.tb17019.x. [PMID: 7834203] - M J Parry, V A Alabaster, H E Cheeseman, K Cooper, R N deSouza, R F Keir. Pharmacological profile of UK-74,505, a novel and selective PAF antagonist with potent and prolonged oral activity.
Journal of lipid mediators and cell signalling.
1994 Sep; 10(3):251-68. doi:
". [PMID: 7812676] - B J O'Connor, S Uden, T J Carty, J D Eskra, P J Barnes, K F Chung. Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.
American journal of respiratory and critical care medicine.
1994 Jul; 150(1):35-40. doi:
10.1164/ajrccm.150.1.8025768. [PMID: 8025768] - F Pons, A G Rossi, K E Norman, T J Williams, S Nourshargh. Role of platelet-activating factor (PAF) in platelet accumulation in rabbit skin: effect of the novel long-acting PAF antagonist, UK-74,505.
British journal of pharmacology.
1993 May; 109(1):234-42. doi:
10.1111/j.1476-5381.1993.tb13559.x. [PMID: 8495241]