Bisindolylmaleimide IX (BioDeep_00000842049)

   


代谢物信息卡片


Bisindolylmaleimide IX

化学式: C25H23N5O2S (457.1572378)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCSC(=N)N
InChI: InChI=1S/C25H23N5O2S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32)

描述信息

C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D004791 - Enzyme Inhibitors

同义名列表

1 个代谢物同义名

Bisindolylmaleimide IX



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
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  • Tianhui Hu, John H Exton. Protein kinase Calpha translocates to the perinuclear region to activate phospholipase D1. The Journal of biological chemistry. 2004 Aug; 279(34):35702-8. doi: 10.1074/jbc.m402372200. [PMID: 15187091]
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  • Alberto Gómez-Ramos, Javier Díaz-Nido, Mark A Smith, George Perry, Jesús Avila. Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells. Journal of neuroscience research. 2003 Mar; 71(6):863-70. doi: 10.1002/jnr.10525. [PMID: 12605413]
  • Luisa Olivi, Jeanne Sisk, Joseph Bressler. The involvement of lipid activators of protein kinase C in the induction of ZIF268 in PC12 cells exposed to lead. Neurochemical research. 2003 Jan; 28(1):65-71. doi: 10.1023/a:1021696011920. [PMID: 12587664]
  • Alessandro Cavarape, Nicole Endlich, Roberta Assaloni, Ettore Bartoli, Michael Steinhausen, Niranjan Parekh, Karlhans Endlich. Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo. Journal of the American Society of Nephrology : JASN. 2003 Jan; 14(1):37-45. doi: 10.1097/01.asn.0000039568.93355.85. [PMID: 12506136]
  • Steven H Young, S Vincent Wu, Enrique Rozengurt. Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C. The Journal of biological chemistry. 2002 Dec; 277(49):46871-6. doi: 10.1074/jbc.m207083200. [PMID: 12356761]
  • Lorella Navazio, Roberto Moscatiello, Daniela Bellincampi, Barbara Baldan, Flavio Meggio, Marisa Brini, Chris Bowler, Paola Mariani. The role of calcium in oligogalacturonide-activated signalling in soybean cells. Planta. 2002 Aug; 215(4):596-605. doi: 10.1007/s00425-002-0776-7. [PMID: 12172842]
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