Vatanidipine (BioDeep_00000842038)
代谢物信息卡片
化学式: C41H42N4O6 (686.3104192000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCCC2=CC=C(C=C2)N3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5)C6=CC(=CC=C6)[N+](=O)[O-])C(=O)OC
InChI: InChI=1S/C41H42N4O6/c1-28-36(40(46)50-3)38(33-15-10-16-35(27-33)45(48)49)37(29(2)42-28)41(47)51-26-21-30-17-19-34(20-18-30)43-22-24-44(25-23-43)39(31-11-6-4-7-12-31)32-13-8-5-9-14-32/h4-20,27,38-39,42H,21-26H2,1-3H3
描述信息
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
D000077264 - Calcium-Regulating Hormones and Agents
D049990 - Membrane Transport Modulators
C93038 - Cation Channel Blocker
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Y Matsumura, K Hayashi. Vatanidipine hydrochloride: a new long-lasting antihypertensive agent.
Expert opinion on investigational drugs.
2001 Jan; 10(1):139-55. doi:
10.1517/13543784.10.1.139. [PMID: 11116287] - T Yamasaki, M Ohmagari, I Tamai, K Hayashi, Y Matsumura. Inhibitory effects of AE0047, a new dihydropyridine Ca(2+) channel blocker, on renal nerve stimulation-induced renal actions in anesthetized dogs.
The Journal of pharmacology and experimental therapeutics.
2000 Jun; 293(3):1040-7. doi:
NULL. [PMID: 10869409] - K Hayashi, T Imada, T Yamauchi, H Kido, H Shinyama, S Matzno, N Nakamura, Y Kagitani. Possible mechanism for the anti-atherosclerotic action of the calcium channel blocker AE0047 in cholesterol-fed rabbits.
Clinical and experimental pharmacology & physiology.
1998 Jan; 25(1):17-25. doi:
10.1111/j.1440-1681.1998.tb02137.x. [PMID: 9493553] - K Hayashi, M Koyama, H Kido, Y Egi, Y Kubo, H Shinyama, M Iwamoto, N Nakamura, Y Kagitani. Preventative and therapeutic effects of AE0047 on renal injury in stroke-prone spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology.
1997 Nov; 24(11):831-40. doi:
10.1111/j.1440-1681.1997.tb02699.x. [PMID: 9363365] - K Yamanaga, H Shinyama, T Akira, M Iwamoto, T Uchida, N Nakamura, Y Kagitani. AE0047-mediated calcium channel blocking in vascular smooth muscles.
General pharmacology.
1997 Sep; 29(3):337-43. doi:
10.1016/s0306-3623(96)00515-0. [PMID: 9378237] - K Hayashi, M Gohda, S Matzno, Y Kubo, H Kido, T Yamauchi, N Nakamura. Possible mechanism of action of AE0047, a calcium antagonist, on triglyceride metabolism.
The Journal of pharmacology and experimental therapeutics.
1997 Aug; 282(2):882-90. doi:
NULL. [PMID: 9262355] - H Kido, M Nishikawa, K Hayashi, Y Kubo, Y Ohtaki, Y Fujino, Y Egi, H Ebisu, S Inoue, K Yamanaga, T Uchida, N Nakamura. [Antihypertensive effects of a novel calcium antagonist, AE0047, in various hypertensive models].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1997 Jun; 109(6):279-89. doi:
10.1254/fpj.109.279. [PMID: 9253775] - H Kido, M Nishikawa, K Hayashi, Y Kubo, H Ebisu, Y Egi, H Shinyama, N Nakamura. [Antihypertensive effects of long-term treatment with AE0047, a novel long-lasting calcium antagonist, in hypertensive models of rats and dogs].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1997 Jun; 109(6):291-301. doi:
10.1254/fpj.109.291. [PMID: 9253776] - K Hayashi, T Uchida, H Kido, H Shinyama, M Watanabe. Effects of AE0047 on renal haemodynamics and function in anaesthetized dogs.
Clinical and experimental pharmacology & physiology.
1993 Feb; 20(2):103-11. doi:
10.1111/j.1440-1681.1993.tb00582.x. [PMID: 8443973]