Isoindole (BioDeep_00000842037)
代谢物信息卡片
Isoindole
化学式: C8H7N (117.0578)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC2=CNC=C2C=C1
InChI: InChI=1S/C8H7N/c1-2-4-8-6-9-5-7(8)3-1/h1-6,9H
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Junrong Wang, Zhifang Wang, Lei Li, Man Wang, Jiaying Chang, Minghong Gao, Dongmei Wang, Chunxia Li. Ultra-small Janus nanoparticle-induced activation of ferroptosis for synergistic tumor immunotherapy.
Acta biomaterialia.
2024 Jun; 181(?):362-374. doi:
10.1016/j.actbio.2024.04.032. [PMID: 38663684] - Sitong Lai, Bing Wang, Kunhui Sun, Fan Li, Qian Liu, Xie-An Yu, Lihe Jiang, Lisheng Wang. Self-Assembled Matrine-PROTAC Encapsulating Zinc(II) Phthalocyanine with GSH-Depletion-Enhanced ROS Generation for Cancer Therapy.
Molecules (Basel, Switzerland).
2024 Apr; 29(8):. doi:
10.3390/molecules29081845. [PMID: 38675664] - Sharayu Govardhane, Pravin Shende. Phthalocyanine-based glucose-responsive nanocochleates for dynamic prevention of β-cell damage in diabetes.
Journal of liposome research.
2024 Mar; 34(1):44-59. doi:
10.1080/08982104.2023.2209642. [PMID: 37171277] - Gang Xiang, Wensi Xu, Wenfeng Zhuge, Qing Huang, Cuizhong Zhang, Jinyun Peng. A Tröger's base-linked aluminium phthalocyanine polymer for discriminative electrochemical sensing of the antibiotic isoniazid.
Analytical methods : advancing methods and applications.
2024 02; 16(7):1012-1020. doi:
10.1039/d3ay02298f. [PMID: 38304962] - Danuta Jantas, Piotr Warszyński, Władysław Lasoń. Carnosic Acid Shows Higher Neuroprotective Efficiency than Edaravone or Ebselen in In Vitro Models of Neuronal Cell Damage.
Molecules (Basel, Switzerland).
2023 Dec; 29(1):. doi:
10.3390/molecules29010119. [PMID: 38202702] - Gang Xiang, Wensi Xu, Wenfeng Zhuge, Qing Huang, Cuizhong Zhang, Jinyun Peng. Conductive phthalocyanine-based porous organic polymer as sensing platform for rapid determination of vanillin.
The Analyst.
2023 Dec; 148(24):6274-6281. doi:
10.1039/d3an01758c. [PMID: 37969078] - Junjie Yao, Lina Wang, Peishan Liu, Mingyang Song, Jiayin Tian, Fan He, Xixiang Ying. A new alkaloid from Portulaca oleracea L. with its anti-inflammatory activity.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2023 Nov; 78(11-12):409-413. doi:
10.1515/znc-2022-0245. [PMID: 37698627] - Pawel Pabisz, Jerzy Bazak, Michal Sabat, Albert W Girotti, Witold Korytowski. Cholesterol Hydroperoxide Co-trafficking in Testosterone-generating Leydig Cells: GPx4 Inhibition of Cytotoxic and Anti-steroidogenic Effects.
Cell biochemistry and biophysics.
2023 Nov; ?(?):. doi:
10.1007/s12013-023-01194-5. [PMID: 37995086] - Itaru Miura, Sho Horikoshi, Mizue Ichinose, Yuhei Suzuki, Kenya Watanabe. Lurasidone for the Treatment of Schizophrenia: Design, Development, and Place in Therapy.
Drug design, development and therapy.
2023; 17(?):3023-3031. doi:
10.2147/dddt.s366769. [PMID: 37789971] - Mingyue Chang, Moru Zhang, Haihong Hu, Shucai Liang. Highly selective fluorescence detection of Pt4+ over Pd2+ and Pt2+ using a polyethyleneimine-based nanosensor prepared via facile three-component reaction.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Oct; 279(?):121466. doi:
10.1016/j.saa.2022.121466. [PMID: 35696970] - Valécia Natália Carvalho da Silva, Emanuel Airton de O Farias, Alyne R Araújo, Francisco Elezier Xavier Magalhães, Jacks Renan Neves Fernandes, Jéssica Maria Teles Souza, Carla Eiras, Durcilene Alves da Silva, Victor Hugo do Vale Bastos, Silmar Silva Teixeira. Rapid and selective detection of dopamine in human serum using an electrochemical sensor based on zinc oxide nanoparticles, nickel phthalocyanines, and carbon nanotubes.
Biosensors & bioelectronics.
2022 Aug; 210(?):114211. doi:
10.1016/j.bios.2022.114211. [PMID: 35468419] - Liu Hu, Huanghuang Chen, Meng Ju, Aiqin Hou, Kongliang Xie, Aiqin Gao. Self-Assembled Nanodot Actuator with Changeable Fluorescence by π-π Stacking Force Based on a Four-Armed Foldable Phthalocyanine Molecule and Its Supersensitive Molecular Recognition.
Nano letters.
2022 08; 22(15):6383-6390. doi:
10.1021/acs.nanolett.2c02244. [PMID: 35866680] - Zhenlong Xu, Lin Mei, Yanmei Shi, Mengyao Yun, Yidan Luan, Zhiqiang Miao, Zhimin Liu, Xiu-Min Li, Mingli Jiao. Multivalent Phthalocyanine-Based Cationic Polymers with Enhanced Photodynamic Activity for the Bacterial Capture and Bacteria-Infected Wound Healing.
Biomacromolecules.
2022 07; 23(7):2778-2784. doi:
10.1021/acs.biomac.2c00145. [PMID: 35666672] - Jing Ding, Yan Zhang, Shanqi Wan, Liu Yang, Xiaohua Cui, Caiping Zhao, Suo Zhang, Zhuocheng Meng. A novel and robust analytical method for the quantification of perospirone in human plasma using an LC-MS/MS system with self-internal standard calibration.
Clinical biochemistry.
2022 Jul; 105-106(?):49-56. doi:
10.1016/j.clinbiochem.2022.04.006. [PMID: 35436467] - Mustafa Akin, Neslihan Saki, Emre Guzel, Batuhan Orman, Ayse Nalbantsoy, Makbule B Kocak. Assessment of in vitro Cytotoxic, iNOS, Antioxidant and Photodynamic Antimicrobial Activities of Water-soluble Sulfonated Phthalocyanines.
Photochemistry and photobiology.
2022 07; 98(4):907-915. doi:
10.1111/php.13558. [PMID: 34748237] - Sijin Hang, Hui Chen, Wenhui Wu, Shiyi Wang, Yiwen Fang, Ruilong Sheng, Qidong Tu, Ruihua Guo. Progress in Isoindolone Alkaloid Derivatives from Marine Microorganism: Pharmacology, Preparation, and Mechanism.
Marine drugs.
2022 Jun; 20(6):. doi:
10.3390/md20060405. [PMID: 35736208] - Galina A Oleinik, Vladimir V Koval, Svetlana V Usova, Larisa N Shishkina, Alexander A Chernonosov. Development and Validation of a Method of Liquid Chromatography Coupled with Tandem Mass Spectrometry for Quantification of ST-246 (Tecovirimat) in Human Plasma.
Molecules (Basel, Switzerland).
2022 Jun; 27(11):. doi:
10.3390/molecules27113577. [PMID: 35684513] - Yikun Wu, Hua Shi, Yuangao Xu, Jun Pei, Shang Song, Wei Chen, Shuxiong Xu. Ebselen ameliorates renal ischemia-reperfusion injury via enhancing autophagy in rats.
Molecular and cellular biochemistry.
2022 Jun; 477(6):1873-1885. doi:
10.1007/s11010-022-04413-4. [PMID: 35338455] - Juliana A Prandini, Kelly A D F Castro, Juliana C Biazzotto, Guilherme T P Brancini, João P C Tomé, Leandro M O Lourenço, Gilberto Ú L Braga, Roberto S da Silva. Thiopyridinium phthalocyanine for improved photodynamic efficiency against pathogenic fungi.
Journal of photochemistry and photobiology. B, Biology.
2022 Jun; 231(?):112459. doi:
10.1016/j.jphotobiol.2022.112459. [PMID: 35512577] - Qianqian Tian, Jinfang Jiang, Hanwei Yin, Jiao Ma, Guozhen Deng, Jialan Zhou, Dafang Zhong. Quantification of the major circulating metabolite of BS1801, an ebselen analog, in human plasma.
Journal of pharmaceutical and biomedical analysis.
2022 Apr; 212(?):114638. doi:
10.1016/j.jpba.2022.114638. [PMID: 35149420] - Ryszard Kubiak, Jan Janczak. Synthesis, Structure, and UV-Vis Characterization of Antimony(III) Phthalocyanine: [(SbPc)2(Sb2I8)(SbBr3)]2.
Molecules (Basel, Switzerland).
2022 Mar; 27(6):. doi:
10.3390/molecules27061839. [PMID: 35335201] - Wilson Luna Machado Alencar, Tiago da Silva Arouche, Abel Ferreira Gomes Neto, Teodorico de Castro Ramalho, Raul Nunes de Carvalho Júnior, Antonio Maia de Jesus Chaves Neto. Interactions of Co, Cu, and non-metal phthalocyanines with external structures of SARS-CoV-2 using docking and molecular dynamics.
Scientific reports.
2022 02; 12(1):3316. doi:
10.1038/s41598-022-07396-w. [PMID: 35228662] - Hannah T Baddock, Sanja Brolih, Yuliana Yosaatmadja, Malitha Ratnaweera, Marcin Bielinski, Lonnie P Swift, Abimael Cruz-Migoni, Haitian Fan, Jeremy R Keown, Alexander P Walker, Garrett M Morris, Jonathan M Grimes, Ervin Fodor, Christopher J Schofield, Opher Gileadi, Peter J McHugh. Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
Nucleic acids research.
2022 02; 50(3):1484-1500. doi:
10.1093/nar/gkab1303. [PMID: 35037045] - Siegfried T D Thun-Hohenstein, Timothy F Suits, Tika R Malla, Anthony Tumber, Lennart Brewitz, Hani Choudhry, Eidarus Salah, Christopher J Schofield. Structure-Activity Studies Reveal Scope for Optimisation of Ebselen-Type Inhibition of SARS-CoV-2 Main Protease.
ChemMedChem.
2022 02; 17(4):e202100582. doi:
10.1002/cmdc.202100582. [PMID: 34850566] - Pawel Pabisz, Jerzy Bazak, Albert W Girotti, Witold Korytowski. Anti-steroidogenic effects of cholesterol hydroperoxide trafficking in MA-10 Leydig cells: Role of mitochondrial lipid peroxidation and inhibition thereof by selenoperoxidase GPx4.
Biochemical and biophysical research communications.
2022 02; 591(?):82-87. doi:
10.1016/j.bbrc.2021.12.117. [PMID: 34999258] - Zydrune Polianskyte-Prause, Tuomas A Tolvanen, Sonja Lindfors, Kanta Kon, Laura C Hautala, Hong Wang, Tsutomu Wada, Hiroshi Tsuneki, Toshiyasu Sasaoka, Sanna Lehtonen. Ebselen enhances insulin sensitivity and decreases oxidative stress by inhibiting SHIP2 and protects from inflammation in diabetic mice.
International journal of biological sciences.
2022; 18(5):1852-1864. doi:
10.7150/ijbs.66314. [PMID: 35342343] - Zhen Qiao, Ningning Wei, Lin Jin, Hongyi Zhang, Jiajie Luo, Yanru Zhang, KeWei Wang. The Mpro structure-based modifications of ebselen derivatives for improved antiviral activity against SARS-CoV-2 virus.
Bioorganic chemistry.
2021 12; 117(?):105455. doi:
10.1016/j.bioorg.2021.105455. [PMID: 34740055] - Mingwen Yang, Zekang Ye, Lianlian Mei, Inam Ullah, Chuchu Tan, Guoyu Wang, Qian Gu, Yi Lu, Samee Abdus, Lu Shi, Xiaoxuan Gong, Jianling Bai, John W Eikelboom, Chunjian Li. Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis.
European journal of clinical pharmacology.
2021 Dec; 77(12):1815-1823. doi:
10.1007/s00228-021-03177-y. [PMID: 34331551] - Scott Parker, June D'Angelo, R Mark Buller, Donald F Smee, Johan Lantto, Henriette Nielsen, Allan Jensen, Mark Prichard, Sarah L George. A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge.
Antiviral research.
2021 11; 195(?):105179. doi:
10.1016/j.antiviral.2021.105179. [PMID: 34530009] - Jonathan W Riess, Karen L Reckamp, Paul Frankel, Jeffrey Longmate, Karen A Kelly, David R Gandara, Caroline M Weipert, Victoria M Raymond, Harold N Keer, Philip C Mack, Edward M Newman, Primo N Lara. Erlotinib and Onalespib Lactate Focused on EGFR Exon 20 Insertion Non-Small Cell Lung Cancer (NSCLC): A California Cancer Consortium Phase I/II Trial (NCI 9878).
Clinical lung cancer.
2021 11; 22(6):541-548. doi:
10.1016/j.cllc.2021.05.001. [PMID: 34140248] - Fuhang Song, Na Yang, Zeinab G Khalil, Angela A Salim, Jiahui Han, Paul V Bernhardt, Rui Lin, Xiuli Xu, Robert J Capon. Bhimamycin J, a Rare Benzo[f]isoindole-dione Alkaloid from the Marine-Derived Actinomycete Streptomyces sp. MS180069.
Chemistry & biodiversity.
2021 Nov; 18(11):e2100674. doi:
10.1002/cbdv.202100674. [PMID: 34609053] - Paulo Sérgio da Silva Santos, Bernardo da Fonseca Orcina, Rafael Rahal Guaragna Machado, Fabiano Vieira Vilhena, Lucas Marques da Costa Alves, Mariana Schutzer Ragghianti Zangrando, Rodrigo Cardoso de Oliveira, Mariana Quirino Silveira Soares, Andréa Name Colado Simão, Emilene Cristine Izu Nakamura Pietro, Juliana Pescinelli Garcia Kuroda, Ivanilda Aparecida de Almeida Benjamim, Danielle Bastos Araujo, Sérgio Hiroshi Toma, Lourival Flor, Koiti Araki, Edison Luiz Durigon. Beneficial effects of a mouthwash containing an antiviral phthalocyanine derivative on the length of hospital stay for COVID-19: randomised trial.
Scientific reports.
2021 10; 11(1):19937. doi:
10.1038/s41598-021-99013-5. [PMID: 34620904] - Paulina Skupin-Mrugalska, Philipp A Elvang, Martin Brandl. Application of Asymmetrical Flow Field-Flow Fractionation for Characterizing the Size and Drug Release Kinetics of Theranostic Lipid Nanovesicles.
International journal of molecular sciences.
2021 Sep; 22(19):. doi:
10.3390/ijms221910456. [PMID: 34638795] - Guolan Wu, Huili Zhou, Jing Wu, Duo Lv, Lihua Wu, You Zhai, Meihua Lin, Jingzi J Wu, Jianzhong Shentu. Pharmacokinetics, Safety, and Tolerability of Ravidasvir, with and without Danoprevir/Ritonavir, in Healthy Subjects.
Antimicrobial agents and chemotherapy.
2021 09; 65(10):e0060021. doi:
10.1128/aac.00600-21. [PMID: 34252301] - Angela Parise, Isabella Romeo, Nino Russo, Tiziana Marino. The Se-S Bond Formation in the Covalent Inhibition Mechanism of SARS-CoV-2 Main Protease by Ebselen-like Inhibitors: A Computational Study.
International journal of molecular sciences.
2021 Sep; 22(18):. doi:
10.3390/ijms22189792. [PMID: 34575955] - Mohamed A Abdel-Lateef, Albandary Almahri. Micellar sensitized Resonance Rayleigh Scattering and spectrofluorometric methods based on isoindole formation for determination of Eflornithine in cream and biological samples.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2021 Sep; 258(?):119806. doi:
10.1016/j.saa.2021.119806. [PMID: 33933938] - Raluca Borlan, Daria Stoia, Luiza Gaina, Andreea Campu, Gabriel Marc, Maria Perde-Schrepler, Mihaela Silion, Dana Maniu, Monica Focsan, Simion Astilean. Fluorescent Phthalocyanine-Encapsulated Bovine Serum Albumin Nanoparticles: Their Deployment as Therapeutic Agents in the NIR Region.
Molecules (Basel, Switzerland).
2021 Aug; 26(15):. doi:
10.3390/molecules26154679. [PMID: 34361832] - Pablo Andrei Nogara, Folorunsho Bright Omage, Gustavo Roni Bolzan, Cássia Pereira Delgado, Michael Aschner, Laura Orian, João Batista Teixeira Rocha. In silico Studies on the Interaction between Mpro and PLpro From SARS-CoV-2 and Ebselen, its Metabolites and Derivatives.
Molecular informatics.
2021 08; 40(8):e2100028. doi:
10.1002/minf.202100028. [PMID: 34018687] - Jennifer C Milligan, Theresa U Zeisner, George Papageorgiou, Dhira Joshi, Christelle Soudy, Rachel Ulferts, Mary Wu, Chew Theng Lim, Kang Wei Tan, Florian Weissmann, Berta Canal, Ryo Fujisawa, Tom Deegan, Hema Nagaraj, Ganka Bineva-Todd, Clovis Basier, Joseph F Curran, Michael Howell, Rupert Beale, Karim Labib, Nicola O'Reilly, John F X Diffley. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease.
The Biochemical journal.
2021 07; 478(13):2499-2515. doi:
10.1042/bcj20210197. [PMID: 34198327] - Claudio Santi, Cecilia Scimmi, Luca Sancineto. Ebselen and Analogues: Pharmacological Properties and Synthetic Strategies for Their Preparation.
Molecules (Basel, Switzerland).
2021 Jul; 26(14):. doi:
10.3390/molecules26144230. [PMID: 34299505] - Le-Yun Sun, Cheng Chen, Jianpeng Su, Jia-Qi Li, Zhihui Jiang, Han Gao, Jia-Zhu Chigan, Huan-Huan Ding, Le Zhai, Ke-Wu Yang. Ebsulfur and Ebselen as highly potent scaffolds for the development of potential SARS-CoV-2 antivirals.
Bioorganic chemistry.
2021 07; 112(?):104889. doi:
10.1016/j.bioorg.2021.104889. [PMID: 33915460] - Lin Mei, Yanmei Shi, Fengyi Cao, Xuan Liu, Xiu-Min Li, Zhenlong Xu, Zhiqiang Miao. PEGylated Phthalocyanine-Functionalized Graphene Oxide with Ultrahigh-Efficient Photothermal Performance for Triple-Mode Antibacterial Therapy.
ACS biomaterials science & engineering.
2021 06; 7(6):2638-2648. doi:
10.1021/acsbiomaterials.1c00178. [PMID: 33938721] - Khaoula Khezami, Kevser Harmandar, Esra Bağda, Efkan Bağda, Gamze Şahin, Nurşen Karakodak, Mahmut Durmuş. BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc(II)phthalocyanines directly substituted with piperazine groups.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
2021 06; 26(4):455-465. doi:
10.1007/s00775-021-01868-6. [PMID: 33944997] - Olga I Yarovaya, Kseniya S Kovaleva, Anna A Zaykovskaya, Liudmila N Yashina, Nadezda S Scherbakova, Dmitry N Scherbakov, Sophia S Borisevich, Fedor I Zubkov, Alexandra S Antonova, Roman Yu Peshkov, Ilia V Eltsov, Oleg V Pyankov, Rinat A Maksyutov, Nariman F Salakhutdinov. New class of hantaan virus inhibitors based on conjugation of the isoindole fragment to (+)-camphor or (-)-fenchone hydrazonesv.
Bioorganic & medicinal chemistry letters.
2021 05; 40(?):127926. doi:
10.1016/j.bmcl.2021.127926. [PMID: 33705902] - Shaya Y Al-Raqa, Khaoula Khezami, Esra N Kaya, Abdulkadir Kocak, Mahmut Durmuş. Experimental and theoretical investigation of water-soluble silicon(IV) phthalocyanine and its interaction with bovine serum albumin.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
2021 05; 26(2-3):235-247. doi:
10.1007/s00775-021-01848-w. [PMID: 33558997] - Zihua Wang, Yunyun Wang, Shengnan Yang, Lan Xue, Wei Feng, Xinran Liu, Binshuai Li, Mengai Yin, Jun Jiao, Qiang Chen. Electrochemical sensor based on magnetic nanohybrids of multiple phthalocyanine doped ferrites/CMWCNTs for detection of rosmarinic acid.
Talanta.
2021 May; 226(?):122165. doi:
10.1016/j.talanta.2021.122165. [PMID: 33676707] - Kirill Sharshov, Mariya Solomatina, Olga Kurskaya, Ilya Kovalenko, Ekaterina Kholina, Vladimir Fedorov, Gennady Meerovich, Andrew Rubin, Marina Strakhovskaya. The Photosensitizer Octakis(cholinyl)zinc Phthalocyanine with Ability to Bind to a Model Spike Protein Leads to a Loss of SARS-CoV-2 Infectivity In Vitro When Exposed to Far-Red LED.
Viruses.
2021 04; 13(4):. doi:
10.3390/v13040643. [PMID: 33918615] - Neeraj S Thakur, Narattam Mandal, Gopal Patel, Seema Kirar, Y Nikhileshwar Reddy, Varun Kushwah, Sanyog Jain, Yogeshvar N Kalia, Jayeeta Bhaumik, Uttam C Banerjee. Co-administration of zinc phthalocyanine and quercetin via hybrid nanoparticles for augmented photodynamic therapy.
Nanomedicine : nanotechnology, biology, and medicine.
2021 04; 33(?):102368. doi:
10.1016/j.nano.2021.102368. [PMID: 33548477] - Ewelina Weglarz-Tomczak, Jakub M Tomczak, Michał Talma, Małgorzata Burda-Grabowska, Mirosław Giurg, Stanley Brul. Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2.
Scientific reports.
2021 02; 11(1):3640. doi:
10.1038/s41598-021-83229-6. [PMID: 33574416] - Christina L Hutson, Ashley V Kondas, Mathew R Mauldin, Jeffrey B Doty, Irma M Grossi, Clint N Morgan, Sharon Dietz Ostergaard, Christine M Hughes, Yoshinori Nakazawa, Chantal Kling, Brock E Martin, James A Ellison, Darin S Carroll, Nadia F Gallardo-Romero, Victoria A Olson. Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model.
mSphere.
2021 02; 6(1):. doi:
10.1128/msphere.00927-20. [PMID: 33536322] - Daifullah Al Aboud, Roua S Baty, Khalaf F Alsharif, Khalid Ebrahim Hassan, Ahmed S Zhery, Ola A Habotta, Ehab K Elmahallawy, Hatim K Amin, Ahmed E Abdel Moneim, Rami B Kassab. Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat.
Environmental science and pollution research international.
2021 Feb; 28(5):6195-6206. doi:
10.1007/s11356-020-10955-1. [PMID: 32989703] - Camilla Servidio, Francesco Stellacci. Therapeutic approaches against coronaviruses acute respiratory syndrome.
Pharmacology research & perspectives.
2021 02; 9(1):e00691. doi:
10.1002/prp2.691. [PMID: 33378565] - Zijing Zhu, Wei Liang, Zhaowei Chen, Jijia Hu, Jun Feng, Yun Cao, Yiqiong Ma, Guohua Ding. Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway.
Oxidative medicine and cellular longevity.
2021; 2021(?):1394486. doi:
10.1155/2021/1394486. [PMID: 34426758] - Sekhar Talluri. Molecular Docking and Virtual Screening Based Prediction of Drugs for COVID-19.
Combinatorial chemistry & high throughput screening.
2021; 24(5):716-728. doi:
10.2174/1386207323666200814132149. [PMID: 32798373] - Yifei Ma, Xuetao Li, Wenjie Zhang, Xixiang Ying, Didier Stien. A trace alkaloid, oleraisoindole A from Portulaca oleracea L. and its anticholinesterase effect.
Natural product research.
2021 Jan; 35(2):350-353. doi:
10.1080/14786419.2019.1627356. [PMID: 31180242] - Karina Mayumi Sakita, Isis Regina Grenier Capoci, Pollyanna Cristina Vincenzi Conrado, Franciele Abigail Vilugron Rodrigues-Vendramini, Daniella Renata Faria, Glaucia Sayuri Arita, Tânia Cristina Alexandrino Becker, Patricia de Souza Bonfim-Mendonça, Terezinha Inez Estivalet Svidzinski, Erika Seki Kioshima. Efficacy of Ebselen Against Invasive Aspergillosis in a Murine Model.
Frontiers in cellular and infection microbiology.
2021; 11(?):684525. doi:
10.3389/fcimb.2021.684525. [PMID: 34249777] - Julia Liang, Chris Karagiannis, Eleni Pitsillou, Kevion K Darmawan, Ken Ng, Andrew Hung, Tom C Karagiannis. Site mapping and small molecule blind docking reveal a possible target site on the SARS-CoV-2 main protease dimer interface.
Computational biology and chemistry.
2020 Dec; 89(?):107372. doi:
10.1016/j.compbiolchem.2020.107372. [PMID: 32911432] - C V Haritha, Khan Sharun, Bosco Jose. Ebselen, a new candidate therapeutic against SARS-CoV-2.
International journal of surgery (London, England).
2020 12; 84(?):53-56. doi:
10.1016/j.ijsu.2020.10.018. [PMID: 33120196] - Khanh T Do, Geraldine O'Sullivan Coyne, John L Hays, Jeffrey G Supko, Stephen V Liu, Kristin Beebe, Len Neckers, Jane B Trepel, Min-Jung Lee, Tomoko Smyth, Courtney Gannon, Jennifer Hedglin, Alona Muzikansky, Susana Campos, John Lyons, Percy Ivy, James H Doroshow, Alice P Chen, Geoffrey I Shapiro. Phase 1 study of the HSP90 inhibitor onalespib in combination with AT7519, a pan-CDK inhibitor, in patients with advanced solid tumors.
Cancer chemotherapy and pharmacology.
2020 12; 86(6):815-827. doi:
10.1007/s00280-020-04176-z. [PMID: 33095286] - Karen Loraine Macena Santos, Rafaella Moreno Barros, Diego Paulo da Silva Lima, Adenia Mirela Alves Nunes, Mariana Rillo Sato, Ricardo Faccio, Bolívar Ponciano Goulart de Lima Damasceno, João Augusto Oshiro-Junior. Prospective application of phthalocyanines in the photodynamic therapy against microorganisms and tumor cells: A mini-review.
Photodiagnosis and photodynamic therapy.
2020 Dec; 32(?):102032. doi:
10.1016/j.pdpdt.2020.102032. [PMID: 33017659] - Abid H Banday, Shameem A Shameem, Sheikh J Ajaz. Potential Repurposed Therapeutics and New Vaccines against COVID-19 and Their Clinical Status.
SLAS discovery : advancing life sciences R & D.
2020 12; 25(10):1097-1107. doi:
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Medicine.
2020 Nov; 99(48):e23357. doi:
10.1097/md.0000000000023357. [PMID: 33235105] - Zhicheng Zhang, Shumei Wang, Xianglin Tu, Xuping Peng, Yanxia Huang, Li Wang, Weihua Ju, Jianfeng Rao, Xue Li, Donghong Zhu, Huabao Sun, Hongyi Chen. A comparative study on the time to achieve negative nucleic acid testing and hospital stays between danoprevir and lopinavir/ritonavir in the treatment of patients with COVID-19.
Journal of medical virology.
2020 11; 92(11):2631-2636. doi:
10.1002/jmv.26141. [PMID: 32501538] - Giftson J Senapathy, Blassan P George, Heidi Abrahamse. Enhancement of Phthalocyanine Mediated Photodynamic Therapy by Catechin on Lung Cancer Cells.
Molecules (Basel, Switzerland).
2020 Oct; 25(21):. doi:
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Acta biomaterialia.
2020 10; 116(?):329-343. doi:
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2020 Oct; 153(?):105491. doi:
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Chemico-biological interactions.
2020 Oct; 330(?):109234. doi:
10.1016/j.cbi.2020.109234. [PMID: 32860823] - Jinsong Zhang, Ramy Saad, Ethan Will Taylor, Margaret P Rayman. Selenium and selenoproteins in viral infection with potential relevance to COVID-19.
Redox biology.
2020 10; 37(?):101715. doi:
10.1016/j.redox.2020.101715. [PMID: 32992282] - Ranjit K Mehta, Sanjima Pal, Koushik Kondapi, Merna Sitto, Cuyler Dewar, Theresa Devasia, Matthew J Schipper, Dafydd G Thomas, Venkatesha Basrur, Manjunath P Pai, Yoshihiro Morishima, Yoichi Osawa, William B Pratt, Theodore S Lawrence, Mukesh K Nyati. Low-Dose Hsp90 Inhibitor Selectively Radiosensitizes HNSCC and Pancreatic Xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020 10; 26(19):5246-5257. doi:
10.1158/1078-0432.ccr-19-3102. [PMID: 32718999] - Natalya Sh Lebedeva, Yury A Gubarev, Mikhail O Koifman, Oskar I Koifman. The Application of Porphyrins and Their Analogues for Inactivation of Viruses.
Molecules (Basel, Switzerland).
2020 Sep; 25(19):. doi:
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Journal of materials chemistry. B.
2020 09; 8(35):8022-8036. doi:
10.1039/d0tb01093f. [PMID: 32766661] - Alice Romeo, Federico Iacovelli, Mattia Falconi. Targeting the SARS-CoV-2 spike glycoprotein prefusion conformation: virtual screening and molecular dynamics simulations applied to the identification of potential fusion inhibitors.
Virus research.
2020 09; 286(?):198068. doi:
10.1016/j.virusres.2020.198068. [PMID: 32565126] - Kangsa Amporndanai, Michael Rogers, Seiji Watanabe, Koji Yamanaka, Paul M O'Neill, S Samar Hasnain. Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
EBioMedicine.
2020 Sep; 59(?):102980. doi:
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Science advances.
2020 09; 6(37):. doi:
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Journal of fluorescence.
2020 Sep; 30(5):1151-1160. doi:
10.1007/s10895-020-02584-1. [PMID: 32648171] - Helmut Sies, Michael J Parnham. Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections.
Free radical biology & medicine.
2020 08; 156(?):107-112. doi:
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Molecular pharmaceutics.
2020 08; 17(8):2779-2788. doi:
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The American journal of clinical nutrition.
2020 08; 112(2):447-448. doi:
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Journal of biomaterials science. Polymer edition.
2020 08; 31(11):1457-1474. doi:
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Dalton transactions (Cambridge, England : 2003).
2020 Jul; 49(28):9605-9617. doi:
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Journal of medicinal chemistry.
2020 07; 63(13):6876-6897. doi:
10.1021/acs.jmedchem.0c00233. [PMID: 32530624] - Bruna Cruz Weber Fulco, Juliano Ten Kathen Jung, Pietro Maria Chagas, Suzan Gonçalves Rosa, Vinicius Costa Prado, Cristina Wayne Nogueira. Diphenyl diselenide is as effective as Ebselen in a juvenile rat model of cisplatin-induced nephrotoxicity.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2020 Jul; 60(?):126482. doi:
10.1016/j.jtemb.2020.126482. [PMID: 32135444] - Beata Brozek-Pluska, Arkadiusz Jarota, Rafal Kania, Halina Abramczyk. Zinc Phthalocyanine Photochemistry by Raman Imaging, Fluorescence Spectroscopy and Femtosecond Spectroscopy in Normal and Cancerous Human Colon Tissues and Single Cells.
Molecules (Basel, Switzerland).
2020 Jun; 25(11):. doi:
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Journal of visualized experiments : JoVE.
2020 05; ?(159):. doi:
10.3791/60957. [PMID: 32421002] - Megan Scudellari. The sprint to solve coronavirus protein structures - and disarm them with drugs.
Nature.
2020 05; 581(7808):252-255. doi:
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ACS applied materials & interfaces.
2020 Apr; 12(15):17193-17206. doi:
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Mar; 228(?):117804. doi:
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Materials science & engineering. C, Materials for biological applications.
2020 Mar; 108(?):110462. doi:
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Molecular biology reports.
2020 Mar; 47(3):2205-2215. doi:
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International journal of nanomedicine.
2020; 15(?):8075-8095. doi:
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Journal of biomedical nanotechnology.
2020 Jan; 16(1):14-28. doi:
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Current topics in medicinal chemistry.
2020; 20(29):2681-2691. doi:
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Marine drugs.
2019 Nov; 17(12):. doi:
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Journal of biomaterials science. Polymer edition.
2019 11; 30(16):1559-1573. doi:
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Journal of agricultural and food chemistry.
2019 Oct; 67(39):10844-10852. doi:
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Photodiagnosis and photodynamic therapy.
2019 Sep; 27(?):39-43. doi:
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Scientific reports.
2019 08; 9(1):11485. doi:
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The journal of physical chemistry. B.
2019 08; 123(30):6515-6520. doi:
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Prostaglandins & other lipid mediators.
2019 08; 143(?):106327. doi:
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