delta-8-Tetrahydrocannabinol (BioDeep_00000841976)
代谢物信息卡片
delta-8-Tetrahydrocannabinol
化学式: C21H30O2 (314.224568)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC1=CC(=C2C3CC(=CCC3C(OC2=C1)(C)C)C)O
InChI: InChI=1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9,12-13,16-17,22H,5-8,10-11H2,1-4H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kerollos Shaker, Andrea Nillas, Ross Ellison, Kelsey Martin, Jordan Trecki, Roy Gerona, Kim Aldy. Delta-8-Tetrahydrocannabinol Exposure and Confirmation in Four Pediatric Patients.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2023 04; 19(2):190-195. doi:
10.1007/s13181-022-00927-x. [PMID: 36757578] - Anders Helander, Malin Johansson, Annika Andersson, Tomas Villén. Analytical and medico-legal problems linked to the presence of delta-8-tetrahydrocannabinol (delta-8-THC): Results from urine drug testing in Sweden.
Drug testing and analysis.
2022 Feb; 14(2):371-376. doi:
10.1002/dta.3190. [PMID: 34734479] - Peter Akpunonu, Regan A Baum, Andrew Reckers, Blake Davidson, Ross Ellison, Matthew Riley, Jordan Trecki, Roy Gerona. Sedation and Acute Encephalopathy in a Pediatric Patient Following Ingestion of Delta-8-Tetrahydrocannabinol Gummies.
The American journal of case reports.
2021 Nov; 22(?):e933488. doi:
10.12659/ajcr.933488. [PMID: 34762615] - Sebastian Rzeppa, Joachim Große, Claudia Rautenberg, Detlef Thieme, Triin Lepp, Henn Vallimäe, Annekathrin M Keiler. Emergence of the less common cannabinoid Δ8 -Tetrahydrocannabinol in a doping sample.
Drug testing and analysis.
2021 Nov; 13(11-12):1936-1943. doi:
10.1002/dta.3159. [PMID: 34494719] - Fatemeh Majdi, Fereshteh Taheri, Pegah Salehi, Majid Motaghinejad, Sepideh Safari. Cannabinoids Δ9-tetrahydrocannabinol and cannabidiol may be effective against methamphetamine induced mitochondrial dysfunction and inflammation by modulation of Toll-like type-4(Toll-like 4) receptors and NF-κB signaling.
Medical hypotheses.
2019 Dec; 133(?):109371. doi:
10.1016/j.mehy.2019.109371. [PMID: 31465975] - Rakesh Awasthi, Guohua An, Maureen D Donovan, Laura L Boles Ponto. Relating Observed Psychoactive Effects to the Plasma Concentrations of Delta-9-Tetrahydrocannabinol and Its Active Metabolite: An Effect-Compartment Modeling Approach.
Journal of pharmaceutical sciences.
2018 02; 107(2):745-755. doi:
10.1016/j.xphs.2017.09.009. [PMID: 28942005] - Bhupendra Patel, Daniel Wene, Zhihua Tina Fan. Qualitative and quantitative measurement of cannabinoids in cannabis using modified HPLC/DAD method.
Journal of pharmaceutical and biomedical analysis.
2017 Nov; 146(?):15-23. doi:
10.1016/j.jpba.2017.07.021. [PMID: 28841427] - Christian D Schubart, Iris E C Sommer, Willemijn A van Gastel, Rogier L Goetgebuer, René S Kahn, Marco P M Boks. Cannabis with high cannabidiol content is associated with fewer psychotic experiences.
Schizophrenia research.
2011 Aug; 130(1-3):216-21. doi:
10.1016/j.schres.2011.04.017. [PMID: 21592732] - Satyanarayana Valiveti, Dana C Hammell, D Caroline Earles, Audra L Stinchcomb. In vitro/in vivo correlation studies for transdermal delta 8-THC development.
Journal of pharmaceutical sciences.
2004 May; 93(5):1154-64. doi:
10.1002/jps.20036. [PMID: 15067692] - P R Stout, C K Horn, D R Lesser. Loss of THCCOOH from urine specimens stored in polypropylene and polyethylene containers at different temperatures.
Journal of analytical toxicology.
2000 Oct; 24(7):567-71. doi:
10.1093/jat/24.7.567. [PMID: 11043661] - T Mavromoustakos, I Daliani. Effects of cannabinoids in membrane bilayers containing cholesterol.
Biochimica et biophysica acta.
1999 Aug; 1420(1-2):252-65. doi:
10.1016/s0005-2736(99)00106-6. [PMID: 10446308] - I Wirguin, R Mechoulam, A Breuer, E Schezen, J Weidenfeld, T Brenner. Suppression of experimental autoimmune encephalomyelitis by cannabinoids.
Immunopharmacology.
1994 Nov; 28(3):209-14. doi:
10.1016/0162-3109(94)90056-6. [PMID: 7852052] - D P Yang, T Mavromoustakos, K Beshah, A Makriyannis. Amphipathic interactions of cannabinoids with membranes. A comparison between delta 8-THC and its O-methyl analog using differential scanning calorimetry, X-ray diffraction and solid state 2H-NMR.
Biochimica et biophysica acta.
1992 Jan; 1103(1):25-36. doi:
10.1016/0005-2736(92)90053-o. [PMID: 1309660] - P Consroe, K Kennedy, K Schram. Assay of plasma cannabidiol by capillary gas chromatography/ion trap mass spectroscopy following high-dose repeated daily oral administration in humans.
Pharmacology, biochemistry, and behavior.
1991 Nov; 40(3):517-22. doi:
10.1016/0091-3057(91)90357-8. [PMID: 1666917] - T Mavromoustakos, D P Yang, W Broderick, D Fournier, A Makriyannis. Small angle x-ray diffraction studies on the topography of cannabinoids in synaptic plasma membranes.
Pharmacology, biochemistry, and behavior.
1991 Nov; 40(3):547-52. doi:
10.1016/0091-3057(91)90361-5. [PMID: 1666918] - A Charalambous, G Marciniak, C Y Shiue, S L Dewey, D J Schlyer, A P Wolf, A Makriyannis. PET studies in the primate brain and biodistribution in mice using (-)-5'-18F-delta 8-THC.
Pharmacology, biochemistry, and behavior.
1991 Nov; 40(3):503-7. doi:
10.1016/0091-3057(91)90354-5. [PMID: 1666914] - P Martel, F U Ahmed. Neutron diffraction from cannabinoids in phospholipid membranes.
Chemistry and physics of lipids.
1990 Mar; 53(4):331-9. doi:
10.1016/0009-3084(90)90030-u. [PMID: 2160334] - V M Papa, M L Shen, D W Ou. The effects of pH and temperature on the in vitro bindings of delta-9-tetrahydrocannabinol and other cannabinoids to bovine serum albumin.
Journal of pharmaceutical and biomedical analysis.
1990; 8(4):353-6. doi:
10.1016/0731-7085(90)80049-u. [PMID: 1966044] - A C Howlett, R M Fleming. Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes.
Molecular pharmacology.
1984 Nov; 26(3):532-8. doi:
NULL. [PMID: 6092901]
