Methyl (1-(4-fluorobenzyl)-1H-indazole-3-carbonyl)-DL-valinate (BioDeep_00000841970)
代谢物信息卡片
化学式: C21H22FN3O3 (383.1645)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)C(C(=O)OC)NC(=O)C1=NN(C2=CC=CC=C21)CC3=CC=C(C=C3)F
InChI: InChI=1S/C21H22FN3O3/c1-13(2)18(21(27)28-3)23-20(26)19-16-6-4-5-7-17(16)25(24-19)12-14-8-10-15(22)11-9-14/h4-11,13,18H,12H2,1-3H3,(H,23,26)
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- David Fabregat-Safont, María Mata-Pesquera, Manuela Barneo-Muñoz, Ferran Martinez-Garcia, Marie Mardal, Anders B Davidsen, Juan V Sancho, Félix Hernández, María Ibáñez. In-depth comparison of the metabolic and pharmacokinetic behaviour of the structurally related synthetic cannabinoids AMB-FUBINACA and AMB-CHMICA in rats.
Communications biology.
2022 02; 5(1):161. doi:
10.1038/s42003-022-03113-5. [PMID: 35210552] - Andrew M Brandon, Lysbeth H Antonides, Jennifer Riley, Ola Epemolu, Denise A McKeown, Kevin D Read, Craig McKenzie. A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market.
Molecules (Basel, Switzerland).
2021 Mar; 26(5):. doi:
10.3390/molecules26051396. [PMID: 33807614] - Jessica A Hvozdovich, Chris W Chronister, Barry K Logan, Bruce A Goldberger. Case Report: Synthetic Cannabinoid Deaths in State of Florida Prisoners.
Journal of analytical toxicology.
2020 Apr; 44(3):298-300. doi:
10.1093/jat/bkz092. [PMID: 31776572] - Florian Franz, Belal Haschimi, Leslie A King, Volker Auwärter. Extraordinary long detection window of a synthetic cannabinoid metabolite in human urine - Potential impact on therapeutic decisions.
Drug testing and analysis.
2020 Mar; 12(3):391-396. doi:
10.1002/dta.2770. [PMID: 31944614] - C S Johnson, C R Stansfield, V R Hassan, E Kolbe, H K Partington, D C Kappatos, R F Somerville. The phenomenon of para-Fluorophenylpiperazine (pFPP) in combination with the synthetic cannabinoid AMB-FUBINACA in seized plant material in New Zealand.
Forensic science international.
2020 Feb; 307(?):110107. doi:
10.1016/j.forsciint.2019.110107. [PMID: 31951949] - Piotr Adamowicz, Ewa Meissner, Marta Maślanka. Fatal intoxication with new synthetic cannabinoids AMB-FUBINACA and EMB-FUBINACA.
Clinical toxicology (Philadelphia, Pa.).
2019 Nov; 57(11):1103-1108. doi:
10.1080/15563650.2019.1580371. [PMID: 30806094] - Rachel Aldridge, Loretta Ford, Sally Bradberry. A curious case of cannabinoid toxicity.
Clinical toxicology (Philadelphia, Pa.).
2019 11; 57(11):1127-1128. doi:
10.1080/15563650.2019.1587449. [PMID: 30862203] - David Fabregat-Safont, Marie Mardal, Carolina Noble, Annelies Cannaert, Christophe P Stove, Juan V Sancho, Kristian Linnet, Félix Hernández, María Ibáñez. Comprehensive investigation on synthetic cannabinoids: Metabolic behavior and potency testing, using 5F-APP-PICA and AMB-FUBINACA as model compounds.
Drug testing and analysis.
2019 Sep; 11(9):1358-1368. doi:
10.1002/dta.2659. [PMID: 31192526] - Ivo D Ivanov, Silviya Stoykova, Elka Ivanova, Aleksandrina Vlahova, Nikola Burdzhiev, Ivayla Pantcheva, Vasil N Atanasov. A case of 5F-ADB / FUB-AMB abuse: Drug-induced or drug-related death?.
Forensic science international.
2019 Apr; 297(?):372-377. doi:
10.1016/j.forsciint.2019.02.005. [PMID: 30850157] - Thomas F Gamage, Charlotte E Farquhar, Timothy W Lefever, Julie A Marusich, Richard C Kevin, Iain S McGregor, Jenny L Wiley, Brian F Thomas. Molecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA.
The Journal of pharmacology and experimental therapeutics.
2018 05; 365(2):437-446. doi:
10.1124/jpet.117.246983. [PMID: 29549157] - Richard J Hamilton, Vadim Keyfes, Sahil S Banka. Synthetic Cannabinoid Abuse Resulting in ST-Segment Elevation Myocardial Infarction Requiring Percutaneous Coronary Intervention.
The Journal of emergency medicine.
2017 Apr; 52(4):496-498. doi:
10.1016/j.jemermed.2016.09.023. [PMID: 27769613] - Axel J Adams, Samuel D Banister, Lisandro Irizarry, Jordan Trecki, Michael Schwartz, Roy Gerona. 'Zombie' Outbreak Caused by the Synthetic Cannabinoid AMB-FUBINACA in New York.
The New England journal of medicine.
2017 01; 376(3):235-242. doi:
10.1056/nejmoa1610300. [PMID: 27973993]
