3-[(2-Benzyl-3-sulfanylpropanoyl)amino]propanoic acid (BioDeep_00000841967)
代谢物信息卡片
3-[(2-Benzyl-3-sulfanylpropanoyl)amino]propanoic acid
化学式: C13H17NO3S (267.0929)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)CC(CS)C(=O)NCCC(=O)O
InChI: InChI=1S/C13H17NO3S/c15-12(16)6-7-14-13(17)11(9-18)8-10-4-2-1-3-5-10/h1-5,11,18H,6-9H2,(H,14,17)(H,15,16)
描述信息
D004791 - Enzyme Inhibitors
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- K Gurbanov, E Shuranyi, A Kaballa, E Fudim, S Blumberg, J Winaver. Renal effects of 2-mercaptoacetyl-L-leucyl-L-phenylalanine, a novel selective inhibitor of neutral endopeptidase 24.11 (Neprilysin): comparison with SQ 28,603.
General pharmacology.
1999 Sep; 33(3):277-81. doi:
10.1016/s0306-3623(99)00014-2. [PMID: 10480661] - M Scheuermann, R Dietz, R Willenbrock. Acute and chronic neutral endopeptidase inhibition and the natriuretic response to acute volume expansion.
European journal of pharmacology.
1998 Apr; 347(2-3):245-52. doi:
10.1016/s0014-2999(98)00106-x. [PMID: 9653889] - C Marie, C Mossiat, C Gros, T Monteil, J Bralet. Effect on prolonged inhibition of neutral endopeptidase on cardiac hypertrophy in rats with myocardial infarction.
Cardiovascular drugs and therapy.
1996 Nov; 10(5):593-8. doi:
10.1007/bf00051002. [PMID: 8950076] - A A Seymour, P D Mathers, B E Abboa-Offei, M M Asaad, H Weber. Renal and depressor activity of C-natriuretic peptide in conscious monkeys: effects of enzyme inhibitors.
Journal of cardiovascular pharmacology.
1996 Sep; 28(3):397-401. doi:
10.1097/00005344-199609000-00008. [PMID: 8877586] - R Willenbrock, M Scheuermann, K Höhnel, F C Luft, R Dietz. Acute and chronic neutral endopeptidase inhibition in rats with aortocaval shunt.
Hypertension (Dallas, Tex. : 1979).
1996 Jun; 27(6):1259-66. doi:
10.1161/01.hyp.27.6.1259. [PMID: 8641733] - A A Seymour, M M Asaad, B E Abboa-Offei, P L Smith, W L Rogers, C R Dorso. Determinants of in vivo activity of neutral endopeptidase 3.4.24.11 and angiotensin converting enzyme inhibitors.
The Journal of pharmacology and experimental therapeutics.
1996 Feb; 276(2):708-13. doi:
NULL. [PMID: 8632340] - A A Seymour, M M Asaad, J H Sheldon, P L Smith, W L Rogers. Atrial natriuretic peptide in chronically hypertensive dogs.
Hypertension (Dallas, Tex. : 1979).
1995 Oct; 26(4):634-41. doi:
10.1161/01.hyp.26.4.634. [PMID: 7558224] - Z A Abassi, S Kotob, E Golomb, F Pieruzzi, H R Keiser. Pulmonary and renal neutral endopeptidase EC 3.4.24.11 in rats with experimental heart failure.
Hypertension (Dallas, Tex. : 1979).
1995 Jun; 25(6):1178-84. doi:
10.1161/01.hyp.25.6.1178. [PMID: 7768560] - A A Seymour, B E Abboa-Offei, P L Smith, P D Mathers, M M Asaad, W L Rogers. Potentiation of natriuretic peptides by neutral endopeptidase inhibitors.
Clinical and experimental pharmacology & physiology.
1995 Jan; 22(1):63-9. doi:
10.1111/j.1440-1681.1995.tb01920.x. [PMID: 7768036] - A A Seymour, M M Asaad, B Abboa-Offei, P L Smith, W L Rogers. Sodium loads enhance the natriuretic responses to atrial natriuretic peptide and neutral endopeptidase inhibitors in conscious cynomolgus monkeys.
Clinical and experimental pharmacology & physiology.
1994 Nov; 21(11):845-56. doi:
10.1111/j.1440-1681.1994.tb02455.x. [PMID: 7882575] - A A Seymour, J H Sheldon, P L Smith, M Asaad, W L Rogers. Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs.
The Journal of pharmacology and experimental therapeutics.
1994 Apr; 269(1):263-70. doi:
NULL. [PMID: 8169834] - N C Trippodo, M Fox, V Natarajan, B C Panchal, C R Dorso, M M Asaad. Combined inhibition of neutral endopeptidase and angiotensin converting enzyme in cardiomyopathic hamsters with compensated heart failure.
The Journal of pharmacology and experimental therapeutics.
1993 Oct; 267(1):108-16. doi:
NULL. [PMID: 8229737] - A A Seymour, M M Asaad, V M Lanoce, K M Langenbacher, S A Fennell, W L Rogers. Systemic hemodynamics, renal function and hormonal levels during inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in conscious dogs with pacing-induced heart failure.
The Journal of pharmacology and experimental therapeutics.
1993 Aug; 266(2):872-83. doi:
NULL. [PMID: 8394922] - A A Seymour, M M Asaad, V M Lanoce, S A Fennell, H S Cheung, W L Rogers. Inhibition of neutral endopeptidase 3.4.24.11 in conscious dogs with pacing induced heart failure.
Cardiovascular research.
1993 Jun; 27(6):1015-23. doi:
10.1093/cvr/27.6.1015. [PMID: 8221758] - M M Asaad, C R Dorso, S M Moreland. Effects of neutral endopeptidase inhibition on the clearance of exogenously administered endothelin in Sprague-Dawley rats.
Journal of cardiovascular pharmacology.
1993 Apr; 21(4):633-6. doi:
10.1097/00005344-199304000-00018. [PMID: 7681910] - Z A Abassi, J Tate, S Hunsberger, H Klein, D Trachewsky, H R Keiser. Pharmacokinetics of ANF and urodilatin during cANF receptor blockade and neutral endopeptidase inhibition.
The American journal of physiology.
1992 Nov; 263(5 Pt 1):E870-6. doi:
10.1152/ajpendo.1992.263.5.e870. [PMID: 1443119] - L Legault, P Cernacek, M Levy, E Maher, D Farber. Renal tubular responsiveness to atrial natriuretic peptide in sodium-retaining chronic caval dogs. A possible role for kinins and luminal actions of the peptide.
The Journal of clinical investigation.
1992 Oct; 90(4):1425-35. doi:
10.1172/jci116009. [PMID: 1328299] - A A Seymour, M M Asaad, B E Abboa-Offei, P L Rovnyak, S Fennell, W L Rogers. Potentiation of brain natriuretic peptides by SQ 28,603, an inhibitor of neutral endopeptidase 3.4.24.11, in monkeys and rats.
The Journal of pharmacology and experimental therapeutics.
1992 Jul; 262(1):60-70. doi:
NULL. [PMID: 1385630] - J P Valentin, C B Qiu, E Wiedemann, D Gardner, M H Humphreys. Inhibition of neutral endopeptidase amplifies the effects of endogenous atrial natriuretic peptide on blood pressure and fluid partition.
American journal of hypertension.
1992 Feb; 5(2):88-91. doi:
10.1093/ajh/5.2.88. [PMID: 1532317] - K B Margulies, M A Perrella, L J McKinley, J C Burnett. Angiotensin inhibition potentiates the renal responses to neutral endopeptidase inhibition in dogs with congestive heart failure.
The Journal of clinical investigation.
1991 Nov; 88(5):1636-42. doi:
10.1172/jci115477. [PMID: 1658047] - A A Seymour, B Abboa-Offei, M M Asaad, W L Rogers. Evaluation of SQ 28,603, an inhibitor of neutral endopeptidase, in conscious monkeys.
Canadian journal of physiology and pharmacology.
1991 Oct; 69(10):1609-17. doi:
10.1139/y91-238. [PMID: 1663819] - N C Trippodo, R A Gabel, C M Harvey, M M Asaad, W L Rogers. Heart failure augments the cardiovascular and renal effects of neutral endopeptidase inhibition in rats.
Journal of cardiovascular pharmacology.
1991 Sep; 18(3):308-16. doi:
10.1097/00005344-199109000-00002. [PMID: 1720829] - K E Dickinson, A A Tymiak, R B Cohen, E C Liu, M L Webb, A Hedberg. Vascular A10 cell membranes contain an endothelin metabolizing neutral endopeptidase.
Biochemical and biophysical research communications.
1991 Apr; 176(1):423-30. doi:
10.1016/0006-291x(91)90941-y. [PMID: 2018530] - A A Seymour, J A Norman, M M Asaad, S A Fennell, B Abboa-Offei, D K Little, V J Kratunis, N G Delaney, J T Hunt, G Di Donato. Possible regulation of atrial natriuretic factor by neutral endopeptidase 24.11 and clearance receptors.
The Journal of pharmacology and experimental therapeutics.
1991 Mar; 256(3):1002-9. doi:
NULL. [PMID: 1826031] - A A Seymour, J A Norman, M M Asaad, S A Fennell, D K Little, V J Kratunis, W L Rogers. Antihypertensive and renal activity of SQ 28,603, an inhibitor of neutral endopeptidase.
Journal of cardiovascular pharmacology.
1991 Feb; 17(2):296-304. doi:
10.1097/00005344-199102000-00016. [PMID: 1709235] - K B Margulies, P G Cavero, A A Seymour, N G Delaney, J C Burnett. Neutral endopeptidase inhibition potentiates the renal actions of atrial natriuretic factor.
Kidney international.
1990 Jul; 38(1):67-72. doi:
10.1038/ki.1990.168. [PMID: 2143548]
