N-(2-Hydroxyethyl)retinamide (BioDeep_00000841949)
代谢物信息卡片
化学式: C22H33NO2 (343.25111580000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NCCO)C)C
InChI: InChI=1S/C22H33NO2/c1-17(8-6-9-18(2)16-21(25)23-14-15-24)11-12-20-19(3)10-7-13-22(20,4)5/h6,8-9,11-12,16,24H,7,10,13-15H2,1-5H3,(H,23,25)/b9-6+,12-11+,17-8+,18-16+
描述信息
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- José Angel Campos-Sandoval, Clara Redondo, Gemma K Kinsella, Akos Pal, Geraint Jones, Gwen S Eyre, Simon C Hirst, John B C Findlay. Fenretinide derivatives act as disrupters of interactions of serum retinol binding protein (sRBP) with transthyretin and the sRBP receptor.
Journal of medicinal chemistry.
2011 Jul; 54(13):4378-87. doi:
10.1021/jm200256g. [PMID: 21591606] - D M McPhillips, J R Kalin, D L Hill. The pharmacokinetics of all-trans-retinoic acid and N-(2-hydroxyethyl)retinamide in mice as determined with a sensitive and convenient procedure. Solid-phase extraction and reverse-phase high performance liquid chromatography.
Drug metabolism and disposition: the biological fate of chemicals.
1987 Mar; 15(2):207-11. doi:
NULL. [PMID: 2882980] - J R Kalin, M J Wells, D L Hill. Effects of phenobarbital, 3-methylcholanthrene, and retinoid pretreatment on disposition of orally administered retinoids in mice.
Drug metabolism and disposition: the biological fate of chemicals.
1984 Jan; 12(1):63-7. doi:
NULL. [PMID: 6141914] - B P Sani, R G Meeks. Subacute toxicity of all-trans- and 13-cis-isomers of N-ethyl retinamide, N-2-hydroxyethyl retinamide, and N-4-hydroxyphenyl retinamide.
Toxicology and applied pharmacology.
1983 Sep; 70(2):228-35. doi:
10.1016/0041-008x(83)90098-4. [PMID: 6226123] - J R Kalin, M J Wells, D L Hill. Disposition of 13-cis-retinoic acid and N-(2-hydroxyethyl)retinamide in mice after oral doses.
Drug metabolism and disposition: the biological fate of chemicals.
1982 Jul; 10(4):391-8. doi:
NULL. [PMID: 6126340] - D F Birt, S Sayed, M H Davies, P Pour. Sex differences in the effects of retinoids on carcinogenesis by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters.
Cancer letters.
1981 Oct; 14(1):13-21. doi:
10.1016/0304-3835(81)90004-5. [PMID: 6457685] - C C Wang, S Campbell, R L Furner, D L Hill. Disposition of all-trans- and 13-cis-retinoic acids and n-hydroxyethylretinamide in mice after intravenous administration.
Drug metabolism and disposition: the biological fate of chemicals.
1980 Jan; 8(1):8-11. doi:
NULL. [PMID: 6102031]